Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_043283366.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043269341.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043271103.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_043270415.1	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70263	"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis"
XP_043279439.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_043284681.1	4	KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26	"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_043281089.1	6	MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-5663	"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_043283016.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043268557.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-3108214	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins"
XP_043268810.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_043272473.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_043273931.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043272642.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043283449.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043277944.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_043280393.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043286425.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043275406.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043275373.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043273643.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-196299	"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade"
XP_043275762.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043276170.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043276742.1	13	Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919	"ECM proteoglycans";"Extracellular matrix organization";"NCAM1 interactions";"Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Collagen degradation";"Collagen chain trimerization";"Signaling by PDGF";"Integrin cell surface interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils"
XP_043289488.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_043276690.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_043275081.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043276131.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043286929.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_043274276.1	5	Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-936440	"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling"
XP_043272755.1	8	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)"
XP_043288775.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043279276.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation"
XP_043290179.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043276206.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_043289042.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043280271.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_043268943.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation"
XP_043283611.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_043281318.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043289151.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043269368.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5689877	"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Josephin domain DUBs"
XP_043275991.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_043285890.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_043282533.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_043272842.1	52	Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-73762	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"mRNA Capping";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation"
XP_043289142.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_043288754.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121	"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI"
XP_043273642.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-432142	"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL"
XP_043278334.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043274347.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043280854.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043270580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043289376.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043271794.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043287361.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043269567.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043282858.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_043272151.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043272254.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043270259.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043276358.1	7	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_043279826.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043285822.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway"
XP_043281092.1	6	MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-7442	"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_043266882.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-177504	"Nef Mediated CD8 Down-regulation";"LDL clearance";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling"
XP_043275836.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_043274876.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_043270048.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043266871.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043287529.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043284302.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043267001.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_043285698.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5632684	"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state"
XP_043286469.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043287452.1	19	MetaCyc: PWY-7176;Reactome: R-HSA-380320;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7184;Reactome: R-HSA-380270;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227	"UTP and CTP de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_043269338.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043286494.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043268177.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5870	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_043287032.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_043285916.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_043279115.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_043270813.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_043286232.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_043276134.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_043268619.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043289767.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_043278685.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_043272778.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_043289878.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043289817.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_043283778.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_043266486.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_043283646.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043279714.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043273419.1	5	Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012	"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043289610.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043270118.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_043275113.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043282853.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_043282652.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_043270128.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_043283405.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043267389.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043271738.1	44	Reactome: R-HSA-5668599;Reactome: R-HSA-8939211;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-162658;Reactome: R-HSA-2559585;Reactome: R-HSA-2029482;Reactome: R-HSA-5675221;Reactome: R-HSA-9635465;Reactome: R-HSA-5674135;Reactome: R-HSA-445144;Reactome: R-HSA-170968;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9634638;Reactome: R-HSA-3371453;Reactome: R-HSA-2559580;Reactome: R-HSA-881907;Reactome: R-HSA-6802946;Reactome: R-HSA-198753;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-1295596;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-202670;Reactome: R-HSA-375165;Reactome: R-HSA-74749;Reactome: R-HSA-2871796;Reactome: R-HSA-6802948;Reactome: R-HSA-5673001;Reactome: R-HSA-879415;Reactome: R-HSA-5654733;Reactome: R-HSA-112409;Reactome: R-HSA-982772;Reactome: R-HSA-2559582;Reactome: R-HSA-5674499;Reactome: R-HSA-444257;Reactome: R-HSA-8943724;Reactome: R-HSA-9649948;Reactome: R-HSA-456926;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-450341;Reactome: R-HSA-9627069	"RHO GTPases Activate NADPH Oxidases";"ESR-mediated signaling";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Golgi Cisternae Pericentriolar Stack Reorganization";"Oncogene Induced Senescence";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of MAPK pathway";"Suppression of apoptosis";"MAP2K and MAPK activation";"Signal transduction by L1";"Frs2-mediated activation";"mTOR signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of HSF1-mediated heat shock response";"Oxidative Stress Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signaling by moderate kinase activity BRAF mutants";"ERK/MAPK targets";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Spry regulation of FGF signaling";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ERKs are inactivated";"NCAM signaling for neurite out-growth";"Signal attenuation";"FCERI mediated MAPK activation";"Signaling by high-kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR4 signaling";"RAF-independent MAPK1/3 activation";"Growth hormone receptor signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Negative feedback regulation of MAPK pathway";"RSK activation";"Regulation of PTEN gene transcription";"Signaling downstream of RAS mutants";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Activation of the AP-1 family of transcription factors";"Regulation of the apoptosome activity"
XP_043275603.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_043280131.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043284096.1	14	KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Ether lipid metabolism"
XP_043278870.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_043283664.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_043279487.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043266848.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_043284852.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043270076.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_043278806.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275727.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043272477.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_043272252.1	12	KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23	"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation"
XP_043275350.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268595.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_043276550.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_043274239.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_043274232.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_043283908.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043271828.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043276817.1	10	KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10	"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Butanoate metabolism"
XP_043282914.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043289060.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043270522.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_043272687.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043269007.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043269164.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043289663.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_043273208.1	11	Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_043285885.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_043278638.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043272240.1	14	KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-6969;Reactome: R-HSA-71403	"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)"
XP_043286780.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025	"Cilium Assembly";"Aggrephagy";"Gap junction assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Kinesins";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation"
XP_043275280.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation"
XP_043273568.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_043290064.1	3	Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2	"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway"
XP_043283294.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043283777.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_043288478.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043285863.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_043276790.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
XP_043266642.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043266530.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_043278793.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043274336.1	6	KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Oxidative phosphorylation";"Photosynthesis";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043275274.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_043281523.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043270712.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043280301.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043289594.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043272788.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism"
XP_043288740.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043269749.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043274709.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043270831.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_043267528.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043276115.1	4	MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_043278128.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation"
XP_043275872.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043282854.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_043283356.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043280801.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_043273439.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043274992.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-114604	"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade"
XP_043273187.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508	"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"HATs acetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_043281877.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043269712.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043276168.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_043286773.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043284166.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_043276288.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_043272243.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043284896.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_043277737.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043278554.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation"
XP_043280515.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043280357.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043278905.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043281194.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043284582.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_043281083.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_043284874.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_043272646.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_043277563.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043289387.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043277197.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043266574.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043278817.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043268036.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043277995.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043282741.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043278808.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043288975.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043281118.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_043273002.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043269522.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_043278824.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_043289516.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_043269008.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043271681.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043268705.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043273092.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043275111.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043284091.1	9	MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-70263;MetaCyc: PWY-6142	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_043269878.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;Reactome: R-HSA-983168	"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043269897.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043286649.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043277894.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_043268375.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_043284016.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043267238.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_043267487.1	6	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_043271986.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043277598.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_043273386.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043280307.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043268980.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043276232.1	18	MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Arginine biosynthesis";"(R)-cysteate degradation";"Tyrosine metabolism";"Cysteine and methionine metabolism"
XP_043286215.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043272566.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043282569.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043278474.1	6	MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13	"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_043272971.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043279060.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_043280409.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_043276110.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_043277193.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043266872.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_043274325.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_043275254.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043282860.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_043275841.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043287248.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_043289772.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043284869.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043278362.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043268180.1	12	MetaCyc: PWY-5872;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-6978;Reactome: R-HSA-1268020	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import"
XP_043286497.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043272305.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043275844.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_043270353.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_043268267.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_043279905.1	16	MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5749;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.4;KEGG: 00020+6.2.1.4;KEGG: 00720+6.2.1.5	"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Itaconate degradation";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_043280664.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043284037.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_043288131.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_043279976.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043287279.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043271298.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_043271285.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043288705.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043274277.1	7	Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_043267239.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_043280836.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_043279434.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_043266900.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_043268706.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043284529.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043271586.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_043277076.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043285180.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_043277603.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_043270601.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043280101.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_043270613.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043280331.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043269240.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043272661.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932	"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB"
XP_043282362.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043268319.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_043282186.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043274209.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_043289185.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_043279027.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091	"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Neddylation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells"
XP_043279525.1	17	KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1	"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Pyruvate metabolism";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_043279585.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043273500.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_043272149.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043281044.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_043281572.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043286314.1	5	Reactome: R-HSA-5668599;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756	"RHO GTPases Activate NADPH Oxidases";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation"
XP_043270716.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_043286072.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043281315.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043290063.1	3	Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807	"Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling"
XP_043272837.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-163560	"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism"
XP_043274016.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043268794.1	9	Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662	"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling"
XP_043274636.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043273925.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043271415.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043272493.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043267256.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043276360.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_043285981.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043273717.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043288033.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597	"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events"
XP_043283623.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043270953.1	3	KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691	"Caffeine metabolism";"Purine metabolism";"Urate conversion to allantoin I"
XP_043289044.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043284671.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_043281781.1	3	KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_043281981.1	3	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression"
XP_043273004.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_043283507.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043280761.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence"
XP_043288041.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043273735.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_043276956.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043273423.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_043271526.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_043270520.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043267129.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors"
XP_043277465.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_043283120.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043284089.1	9	MetaCyc: PWY-6142;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes"
XP_043285338.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043275355.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043278291.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_043282443.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043288269.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress"
XP_043268933.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043276150.1	4	MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_043282808.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_043270759.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_043278582.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043269925.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043275791.1	18	MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_043284247.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043276777.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043269150.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043286516.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate"
XP_043274382.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043279763.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043278900.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes"
XP_043268215.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043272437.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043283457.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043282211.1	14	MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-3841	"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate polyglutamylation";"Methane metabolism";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate";"Cyanoamino acid metabolism";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)"
XP_043287210.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043276166.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_043273754.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043269315.1	8	Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-163754;Reactome: R-HSA-6791055;Reactome: R-HSA-71336	"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway"
XP_043283183.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043275577.1	9	KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5	"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine metabolism";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism"
XP_043285185.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043266758.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043267028.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation"
XP_043266720.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_043273103.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043290173.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043283867.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21	"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism"
XP_043268671.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043286529.1	13	MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-6672;Reactome: R-HSA-71384;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1	"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Ethanol oxidation";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism"
XP_043276272.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043267282.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_043282929.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_043279443.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043272338.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043288151.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480	"Chylomicron clearance";"VLDL clearance";"LDL remodeling";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Chylomicron assembly";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of TLR by endogenous ligand";"LDL clearance";"Scavenging by Class A Receptors"
XP_043280392.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043268277.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043280303.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_043272605.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043279006.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043289324.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043272357.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;MetaCyc: PWY-7221	"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis"
XP_043278795.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043279201.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043290177.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_043282568.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043284659.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043270553.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_043280817.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043273265.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043286217.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043274295.1	12	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle";"mTOR signaling pathway";"Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043280129.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043276225.1	6	MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_043272609.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043268867.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043281935.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043269822.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5687128	"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Neddylation";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling"
XP_043284900.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-202733	"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall"
XP_043271035.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_043269232.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043266410.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_043275690.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043280215.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043267432.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_043289104.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043276231.1	25	Reactome: R-HSA-380270;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148	"Recruitment of mitotic centrosome proteins and complexes";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043285189.1	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_043275990.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_043289012.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_043280330.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043286510.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_043284573.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043280805.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-606279	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_043284328.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043289432.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043266780.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043279263.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043278941.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043276570.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043287058.1	13	KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-2261;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;Reactome: R-HSA-196836;MetaCyc: PWY-6370	"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Glutathione conjugation";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Ascorbate recycling (cytosolic)"
XP_043279125.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_043272630.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-6799198	"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis"
XP_043278801.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043280746.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_043273030.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_043287761.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043287673.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043279114.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_043268343.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_043272898.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events"
XP_043266576.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_043281706.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043272679.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_043268049.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_043270892.1	11	KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-7400;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-5154;MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;KEGG: 00240+6.3.5.5;Reactome: R-HSA-500753	"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_043271059.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043289299.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_043267634.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_043272524.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043279440.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043280622.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_043289700.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_043276029.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_043278462.1	8	MetaCyc: PWY-6664;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6580	"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_043273736.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_043274378.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096	"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation";"HS-GAG degradation"
XP_043287255.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-165054	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA"
XP_043268455.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253	"Generic Transcription Pathway";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock"
XP_043269948.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043269381.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043280598.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_043284894.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_043282805.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043272460.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043286503.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043279614.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043280204.1	15	Reactome: R-HSA-9665247;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9665249;Reactome: R-HSA-1227986;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-9665245;Reactome: R-HSA-9665233;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9665244;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382	"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"
XP_043272405.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043276588.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043276835.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_043288750.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135	"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual incision in TC-NER"
XP_043286414.1	8	KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;MetaCyc: PWY-8086;MetaCyc: PWY-6901	"Cysteine and methionine metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation"
XP_043271937.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043289867.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043280383.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_043268141.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_043269318.1	8	Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-163754;Reactome: R-HSA-6791055;MetaCyc: PWY-1861;MetaCyc: PWY-5723	"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt"
XP_043268202.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043275064.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043270810.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043286277.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_043272331.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043283052.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043271717.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043280454.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043279609.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_043270027.1	9	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol"
XP_043285905.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_043288884.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043280118.1	6	Reactome: R-HSA-3371599;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181	"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Biotin metabolism";"Lipoic acid metabolism"
XP_043269921.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_043277774.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_043283951.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043266841.1	11	KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-5381;MetaCyc: PWY-7185;MetaCyc: PWY-6607;MetaCyc: PWY-7821;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5	"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Pyrimidine metabolism"
XP_043284007.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043272641.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043276284.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043274536.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043280327.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043274056.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_043269947.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043275392.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_043286078.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043283057.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_043282175.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043268676.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_043277070.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_043272257.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043276980.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_043267518.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043266889.1	20	Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1	"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"mTOR signalling";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"mTOR signaling pathway";"Macroautophagy";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway"
XP_043283079.1	5	MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_043273626.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_043276641.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043289557.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043275763.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043267281.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_043275195.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043271466.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043270671.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043287435.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_043287399.1	3	Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669	"Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_043275918.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043289442.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_043275833.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_043289845.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_043279295.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043273603.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043273425.1	20	MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7606	"Propanoyl-coa degradation II";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_043278939.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043276120.1	3	MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96	"L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis"
XP_043285894.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043287747.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043268561.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_043287222.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-9603505;Reactome: R-HSA-167287	"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NTRK3 as a dependence receptor";"HIV elongation arrest and recovery"
XP_043288567.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_043272332.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043279004.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043279219.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_043278560.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043267135.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043286179.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043266635.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043271664.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_043280804.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043281688.1	30	Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-5610780;Reactome: R-HSA-2122947;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-2871837;Reactome: R-HSA-2644607;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5684264	"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Prolactin receptor signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Degradation of GLI1 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Iron uptake and transport";"FCERI mediated NF-kB activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_043274357.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043279543.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571	"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)"
XP_043277077.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043285352.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043286194.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_043278460.1	8	MetaCyc: PWY-2301;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-4661;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664	"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis"
XP_043277591.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043281239.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043273699.1	4	KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_043282990.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043274864.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_043279953.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_043271348.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_043277895.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_043289156.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-901042	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle"
XP_043267979.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_043282583.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_043286219.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043272608.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043281172.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043277651.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043268209.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_043271788.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043286403.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043283798.1	13	MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7254	"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)"
XP_043266958.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_043281527.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043282152.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043276560.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043287121.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043287809.1	14	Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110314	"Polymerase switching";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex"
XP_043276534.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043267431.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043267408.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043288942.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043285271.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043269207.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043288521.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043287604.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_043272179.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043271764.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043289859.1	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7902	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis"
XP_043268560.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_043283494.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_043282042.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043284479.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043284199.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs"
XP_043282255.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_043287989.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043278347.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043287230.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I"
XP_043282073.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043283901.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043278394.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043281251.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043282792.1	1	Reactome: R-HSA-419771	"Opsins"
XP_043286485.1	17	KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-69601;KEGG: 04150+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-69473;Reactome: R-HSA-8953750	"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"mTOR signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6"
XP_043272435.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043272306.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043268403.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-5080	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I"
XP_043280785.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043278491.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043272402.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043275402.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043279360.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043270278.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_043287402.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043281945.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin"
XP_043280450.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043279613.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043289514.1	4	Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_043269709.1	19	Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888	"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Chylomicron clearance";"VLDL clearance";"Retinoid metabolism and transport";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL clearance";"Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Chylomicron assembly"
XP_043266700.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_043275787.1	7	MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_043276758.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043271662.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043277168.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043271192.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043277992.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043283726.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043280964.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_043279829.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043284258.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_043272173.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043271838.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_043272190.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043272234.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_043289368.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043278688.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_043288430.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_043284303.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043284944.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_043276557.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043275032.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043285363.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043278357.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_043268881.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism"
XP_043288554.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_043281596.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043272406.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_043279204.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043280205.1	15	Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9665249;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-1227986;Reactome: R-HSA-9665245;Reactome: R-HSA-9665233;Reactome: R-HSA-9665250;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9665244	"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib"
XP_043278926.1	10	Reactome: R-HSA-1855191;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6369	"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis"
XP_043278061.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_043274192.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043274596.1	8	MetaCyc: PWY-5154;MetaCyc: PWY-5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-4983;MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Urea cycle";"Arginine biosynthesis"
XP_043288139.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043278816.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043284655.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_043281790.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043284597.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_043274275.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6351	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_043276960.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043271006.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043272096.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_043284242.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043276354.1	14	MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667	"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_043277959.1	22	Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6958;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7728;MetaCyc: PWY-7725;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_043277402.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_043279580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283338.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_043279074.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043286010.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043279485.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_043278818.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043269322.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_043281544.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_043271350.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"RAF activation"
XP_043286670.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_043288056.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043284670.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_043280849.1	7	MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7791	"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis III"
XP_043269970.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283605.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043287717.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822	"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)"
XP_043268154.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043272683.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043279086.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043282172.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043283660.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)"
XP_043271790.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616	"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043267527.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043268016.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043281269.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_043286792.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043280554.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043281127.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_043278522.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_043274756.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_043284816.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL"
XP_043275634.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043267800.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-8951664;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043287706.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043274647.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043276379.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_043278406.1	14	MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_043274659.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_043274661.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_043271529.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043267324.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_043274438.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043268374.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_043270276.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_043280896.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_043268908.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_043269085.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_043275637.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043279784.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_043286813.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043282981.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043269716.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043269575.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043270772.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_043284901.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043274511.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_043271720.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043278852.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043281062.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043288635.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043276125.1	4	MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_043289111.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_043270883.1	10	Reactome: R-HSA-2142789;MetaCyc: PWY-5891;MetaCyc: PWY-5890;MetaCyc: PWY-5895;MetaCyc: PWY-5844;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5839	"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis"
XP_043276948.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_043285650.1	11	MetaCyc: PWY-7560;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7102;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-7391	"Methylerythritol phosphate pathway II";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_043278521.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_043272625.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043269382.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043287751.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043268563.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_043276957.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_043289966.1	2	Reactome: R-HSA-2142789;Reactome: R-HSA-983168	"Ubiquinol biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043278495.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043280565.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043272092.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_043272270.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_043273929.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043282455.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_043274872.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_043269651.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_043267454.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_043286579.1	18	MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-6545	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_043275247.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043268257.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043279573.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278481.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043270619.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate cycle"
XP_043271605.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043287584.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043270074.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_043281045.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_043288469.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_043280686.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043279174.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043269039.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_043285354.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043290168.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043277204.1	9	MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Nitrogen metabolism"
XP_043269022.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043268454.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_043277645.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_043279047.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043286615.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043268373.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_043277597.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_043268481.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_043281598.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043285172.1	8	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Activation of RAC1"
XP_043286379.1	12	KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801	"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)"
XP_043284911.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043270761.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_043285580.1	42	Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-2299718;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-3214847	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"DNA methylation";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"HCMV Late Events";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Condensation of Prophase Chromosomes";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"HATs acetylate histones"
XP_043281953.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_043285753.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043272346.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043278396.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043273930.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043271674.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_043285915.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_043278947.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_043272098.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_043271018.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043269125.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043280589.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043285873.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_043276537.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043276261.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043289107.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_043278494.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043282469.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_043278684.1	4	KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)"
XP_043277075.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043266456.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_043273788.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_043275871.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043269129.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043279589.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043279135.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_043271070.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043279560.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043269693.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_043276966.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-5651801	"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair"
XP_043268015.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043281747.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043266385.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_043266390.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043283710.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_043271743.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_043288633.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043279850.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043289701.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_043269083.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_043287286.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043274708.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043288474.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043280736.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043267627.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_043279831.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043283432.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_043269463.1	16	Reactome: R-HSA-182218;Reactome: R-HSA-196025;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-8964038;Reactome: R-HSA-190873;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-177504	"Nef Mediated CD8 Down-regulation";"Formation of annular gap junctions";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"LDL clearance";"Gap junction degradation";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling"
XP_043271541.1	33	Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-4551638	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins"
XP_043267561.1	6	MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_043280095.1	1	Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH2"
XP_043284598.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_043278938.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-350562	"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)"
XP_043287289.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043272664.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952	"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions"
XP_043268568.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_043271364.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_043281438.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_043279989.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043289720.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_043272177.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043287523.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043272267.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_043281096.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043290048.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Recycling pathway of L1";"Aggrephagy";"Cilium Assembly";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Mitotic Prometaphase"
XP_043266878.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35	"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism"
XP_043287764.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043278136.1	18	Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_043283461.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043268033.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_043272476.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_043289467.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043270306.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043281746.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043273665.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043268132.1	10	KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15	"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism"
XP_043270212.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043277105.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_043272869.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043285167.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043268156.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043271441.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_043272666.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673000	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF activation"
XP_043276498.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043286812.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_043280758.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043286092.1	5	MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_043281594.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043285853.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_043268248.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043271883.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_043268917.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_043284713.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938	"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)"
XP_043276838.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043280029.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043273738.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_043287308.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_043284611.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043286400.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043287835.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043279830.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043284973.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_043267984.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043283030.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_043269148.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043285361.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043269060.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_043277958.1	22	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7727;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_043276238.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_043268032.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_043288124.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043286076.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043273060.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043280860.1	19	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728	"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle"
XP_043267005.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_043289981.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_043280041.1	11	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;Reactome: R-HSA-171007	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"p38MAPK events"
XP_043270072.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_043271343.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043280742.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_043288353.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043283866.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_043279691.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043285341.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043278162.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_043269946.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043277695.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_043275115.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043285082.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_043288105.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043278431.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_043280232.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043274521.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043285280.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043279787.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_043276300.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_043281592.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043269617.1	4	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_043267134.1	4	Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors"
XP_043286706.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043273181.1	12	Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-73762;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_043287763.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043272593.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043269174.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_043273009.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043277633.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_043283032.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043267559.1	6	MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_043288130.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_043267429.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043266577.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_043271543.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_043274173.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_043279930.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043268598.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_043281229.1	13	Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325	"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_043275775.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043268129.1	10	KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15	"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism"
XP_043278558.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043278013.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043266636.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043268496.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043270271.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043281052.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043289367.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043268228.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_043278723.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043266693.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043269601.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043279110.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_043270602.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043282894.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043289037.1	5	Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201	"Metabolism of folate and pterines";"Folate transformations II (plants)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations I"
XP_043288752.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_043281434.1	13	Reactome: R-HSA-8876725;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-532668	"Protein methylation";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"ABC-family proteins mediated transport";"HSF1 activation";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043289852.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_043270360.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043269223.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043272308.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043287708.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481	"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints"
XP_043288341.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043274710.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043289643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043270071.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_043275333.1	5	Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300	"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA"
XP_043279854.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043273056.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_043269136.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043288495.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043287762.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043283118.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043270929.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-68877	"Recycling pathway of L1";"RHO GTPases Activate Formins";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Mitotic Prometaphase"
XP_043287234.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_043274547.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_043271482.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5632684	"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state"
XP_043269535.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043274578.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_043288836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043276196.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043287606.1	9	KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476	"Inositol phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events"
XP_043272436.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043289632.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_043267756.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_043289604.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043271718.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043281190.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043278053.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043273346.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_043276962.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_043275967.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941	"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses"
XP_043282258.1	5	MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560	"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II"
XP_043274094.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_043281193.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043273675.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278154.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043268662.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043273635.1	12	MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_043272888.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043272917.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043271444.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043280997.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_043277605.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043283313.1	17	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043284250.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043283393.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043288134.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043276773.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_043270771.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043269320.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_043270104.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_043269711.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043285872.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_043280234.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043276310.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043269002.1	18	Reactome: R-HSA-1483166;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4	"Synthesis of PA";"Plasmalogen degradation";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism"
XP_043279524.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_043273753.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043280875.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043285104.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_043279209.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043272349.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043288468.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043272259.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_043274824.1	7	KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_043276844.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043285026.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043285272.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_043283060.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_043266671.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_043272759.1	3	Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_043280317.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_043280523.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043271921.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_043288796.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043288086.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
XP_043278907.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043268886.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043289978.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_043285966.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_043282575.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043278882.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043275465.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043276274.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043281468.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043275218.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_043287968.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_043275486.1	3	KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle"
XP_043272890.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins"
XP_043271694.1	7	MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-6471;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227	"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis"
XP_043282822.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043267447.1	6	Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_043268981.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043269531.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043284361.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_043275703.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043280810.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8	"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_043270384.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_043286981.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_043286705.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043289326.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_043278320.1	6	MetaCyc: PWY-7820;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22	"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism"
XP_043289152.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043278286.1	18	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_043270081.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_043287225.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043272256.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043283610.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043273678.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043289403.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_043282192.1	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_043289353.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408	"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Attenuation phase";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation"
XP_043285585.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043270578.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278390.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043272600.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_043277194.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043268552.1	10	Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043269525.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043272631.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043286707.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043281881.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_043272424.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_043266849.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_043286139.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043283358.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043279117.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_043278928.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6369;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_043288155.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_043276959.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043284371.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043289853.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_043277596.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_043288475.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043274619.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043286059.1	6	MetaCyc: PWY-6906;MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_043283028.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043279076.1	5	KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-8856828	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis"
XP_043271767.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_043278505.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_043272000.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043276517.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_043288978.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043268556.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043278635.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043276380.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_043272864.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043276233.1	18	MetaCyc: PWY-7117;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Tyrosine metabolism";"Cysteine and methionine metabolism"
XP_043287684.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043278562.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043275753.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043273724.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231	"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production"
XP_043281882.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_043280830.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_043271284.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043283394.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043276837.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043287252.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746	"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein"
XP_043268904.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043269456.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_043278213.1	11	Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196	"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling"
XP_043267000.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_043273000.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043280269.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_043279992.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043273696.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-72731	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP"
XP_043280273.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_043287031.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_043286042.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043273093.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)"
XP_043270606.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043274080.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043276488.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043269197.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling"
XP_043285821.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_043267007.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_043275764.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043284244.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043273246.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043280796.1	17	Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167238;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043277253.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_043272322.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_043283077.1	5	MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism"
XP_043288664.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043279615.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043269597.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043273926.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043286328.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_043271014.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_043283545.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043276267.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043277511.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_043269321.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_043280620.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_043280759.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043286515.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_043270618.1	8	MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-241	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_043278338.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043288939.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043278944.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043272368.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-6784531	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus"
XP_043273001.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043274852.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-373753	"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"COPI-mediated anterograde transport";"Nephrin family interactions"
XP_043278553.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340	"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation"
XP_043288121.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_043276489.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043272525.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043283659.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-3232118	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of transcription factors"
XP_043268379.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_043286818.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_043269198.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_043272413.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043269680.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043287743.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043285020.1	42	Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-3214858;Reactome: R-HSA-9616222	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"HCMV Early Events";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"DNA methylation";"Packaging Of Telomere Ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RMTs methylate histone arginines";"Transcriptional regulation of granulopoiesis"
XP_043272279.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Signaling by Hippo";"Relaxin signaling pathway";"Thermogenesis"
XP_043276246.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191	"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC"
XP_043283945.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273212.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_043270675.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043274978.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_043279203.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043278335.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043285407.1	5	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_043278057.1	14	Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-69273	"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_043270150.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043270233.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_043288006.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043272366.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_043286980.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043279688.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_043285937.1	6	Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043280097.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043282816.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043286420.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043277272.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_043270006.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_043286645.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043266648.1	10	MetaCyc: PWY-7184;MetaCyc: PWY-7199;MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45;Reactome: R-HSA-69205;MetaCyc: PWY-3841;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_043268369.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043276194.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043284528.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043270816.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_043272412.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423	"Chylomicron assembly";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class B Receptors";"LDL clearance";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Retinoid metabolism and transport";"VLDL clearance";"Chylomicron clearance";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly"
XP_043290183.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_043266890.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-6556;MetaCyc: PWY-7193;Reactome: R-HSA-73614;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5	"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_043271930.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043277271.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_043289249.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_043270608.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043276062.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_043272478.1	12	Reactome: R-HSA-6804756;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382	"Regulation of TP53 Activity through Phosphorylation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex"
XP_043271749.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6606	"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II"
XP_043289186.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_043267948.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043281577.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_043266860.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043273958.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_043282105.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway"
XP_043276919.1	12	Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340	"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Purine metabolism";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfate activation for sulfonation"
XP_043271459.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043268325.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043271380.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_043287453.1	19	MetaCyc: PWY-6545;Reactome: R-HSA-380270;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7176;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_043270604.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043276970.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_043273424.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_043268316.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_043289612.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043280449.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043277466.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_043267227.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043285340.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043285479.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_043272606.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043282055.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043289105.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_043273628.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_043286564.1	14	MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-1622;MetaCyc: PWY-7218;MetaCyc: PWY-6142	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Methane metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Formaldehyde assimilation I (serine pathway)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_043279517.1	17	MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression"
XP_043275114.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043271417.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043269877.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;Reactome: R-HSA-983168	"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043286417.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043286843.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043273532.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825	"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_043285487.1	4	Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20	"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism"
XP_043269319.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_043271892.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_043269264.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043281590.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043281095.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043277111.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_043274300.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043273833.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043273006.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043267372.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043285697.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_043274823.1	7	KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6121;MetaCyc: PWY-6277	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_043267277.1	18	Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_043274638.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_043280386.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043284758.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_043271583.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_043272893.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043267575.1	5	KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937	"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Iron uptake and transport"
XP_043281519.1	6	KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_043279856.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043269969.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043268208.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043279719.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043276776.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633	"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_043272340.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043283719.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_043277496.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043273394.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043273623.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_043276727.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043268995.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_043273775.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_043278391.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043287702.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043289613.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043278448.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_043290135.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_043271279.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_043278968.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_043281782.1	3	KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_043289611.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043270860.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043278564.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043282210.1	14	KEGG: 00670+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3661	"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Methane metabolism";"Metabolism of folate and pterines";"Glycine betaine degradation I"
XP_043285350.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043274432.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_043280747.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043285323.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)"
XP_043280308.1	11	Reactome: R-HSA-167161;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"HIV Transcription Initiation";"Ub-specific processing proteases";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_043267365.1	14	KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5078;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-7767;Reactome: R-HSA-70895;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057	"Cysteine and methionine metabolism";"L-leucine degradation III";"L-isoleucine degradation II";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"Branched-chain amino acid catabolism";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine degradation";"L-valine degradation II"
XP_043269603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278301.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"HIV Transcription Initiation"
XP_043272438.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043266412.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_043268353.1	29	Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation"
XP_043269189.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043267757.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_043287127.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275789.1	7	KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_043277804.1	12	Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043273408.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043274326.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_043282215.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_043274495.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_043282052.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043284775.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043271851.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_043279488.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043287758.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043269611.1	3	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_043280350.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043282297.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043277474.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_043279340.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_043270581.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283943.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043280274.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_043270318.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_043284114.1	10	MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway"
XP_043267119.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043271520.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043267558.1	6	MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5653	"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_043277653.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_043279208.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043280119.1	3	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_043269677.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180	"Neutrophil degranulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation"
XP_043285851.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043269437.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_043285862.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_043287401.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043281472.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043278744.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043271827.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_043279193.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043272228.1	3	Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_043266869.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043278284.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_043277256.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043281926.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_043284895.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_043279277.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662	"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling"
XP_043270710.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043268944.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514	"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_043280117.1	6	KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_043283800.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism"
XP_043271939.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043278569.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043289370.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043278568.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043288674.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043287428.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043278305.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_043277550.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_043282848.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043285919.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043283355.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043277625.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_043288888.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_043273863.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_043279057.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043270041.1	9	Reactome: R-HSA-6782315;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756	"tRNA modification in the nucleus and cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation"
XP_043281494.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043269237.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043273755.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043278492.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043286835.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_043286484.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043284811.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043287629.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_043280253.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_043279164.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043270264.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043285233.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043280969.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_043274245.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_043284358.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_043266858.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043283297.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043266450.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043278579.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043281390.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043274466.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043285171.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043270020.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-165054	"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA"
XP_043278125.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_043280825.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043286931.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043284581.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_043282562.1	10	Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043279988.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043280816.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043287720.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043287962.1	30	Reactome: R-HSA-69202;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-9634638;Reactome: R-HSA-389357;Reactome: R-HSA-6804758;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1358803;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-111447;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-8948751;Reactome: R-HSA-211163;Reactome: R-HSA-198693;Reactome: R-HSA-389513;Reactome: R-HSA-6804759;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-8876198;Reactome: R-HSA-9614399;Reactome: R-HSA-199418;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Activity through Acetylation";"PI3K-Akt signaling pathway";"RUNX2 regulates genes involved in cell migration";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Downregulation of ERBB2:ERBB3 signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Activation of BAD and translocation to mitochondria";"mTOR signaling pathway";"PIP3 activates AKT signaling";"Regulation of PTEN stability and activity";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the nucleus";"CTLA4 inhibitory signaling";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of localization of FOXO transcription factors";"Negative regulation of the PI3K/AKT network";"Cyclin A:Cdk2-associated events at S phase entry"
XP_043281379.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043269616.1	4	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_043275142.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043278330.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043288397.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043276188.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_043282470.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_043268663.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043270255.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043269571.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043284082.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_043272649.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF activation";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade"
XP_043286511.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_043273483.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_043278388.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043279046.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043287844.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043271063.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043275602.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_043270756.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043289773.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043270769.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_043287704.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043288050.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_043271438.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043274703.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_043279420.1	6	MetaCyc: PWY-6608;MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3	"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism"
XP_043283698.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043272717.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043287685.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043286709.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043276739.1	13	Reactome: R-HSA-2214320;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157	"Anchoring fibril formation";"Signaling by PDGF";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Extracellular matrix organization";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Laminin interactions"
XP_043282059.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043275750.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043286456.1	11	MetaCyc: PWY-6964;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2	"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Nitrogen metabolism";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism"
XP_043270611.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780	"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome"
XP_043282249.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043268300.1	8	Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_043266637.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043269977.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530	"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_043283724.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_043270694.1	7	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943	"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates"
XP_043270758.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_043286276.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_043287658.1	18	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-6803	"Ether lipid metabolism";"Plasmalogen degradation";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing"
XP_043276861.1	7	MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-6134	"L-phenylalanine degradation V";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"L-tyrosine biosynthesis IV"
XP_043269804.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043279522.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_043283363.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043273005.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_043285675.1	29	Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-427413	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression"
XP_043274512.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_043272271.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_043274405.1	13	KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3	"One carbon pool by folate";"Metabolism of folate and pterines";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Carbon fixation pathways in prokaryotes"
XP_043279764.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043268975.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043266618.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
XP_043278858.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043275747.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043284932.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_043279116.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_043266721.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_043270574.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275869.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043272580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043268635.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043277911.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043269519.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043271107.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043288523.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043284262.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043269685.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043290180.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_043272178.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043276728.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043281091.1	6	Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_043267557.1	6	MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1	"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_043285447.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043271069.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043280157.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043285101.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_043273051.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_043287042.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_043273169.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043274168.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043280158.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_043279206.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043282454.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_043283133.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_043274230.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_043286628.1	7	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex"
XP_043270826.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043286530.1	13	KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;Reactome: R-HSA-71384;MetaCyc: PWY-6672;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118	"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Ethanol oxidation";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol"
XP_043275060.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043287249.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_043286398.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043273924.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043284792.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043274730.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_043288717.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_043281015.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809	"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization"
XP_043280146.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043287285.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043284256.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_043280864.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043267976.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043287891.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043280787.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043278499.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_043272302.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_043269560.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043285349.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043288268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043281421.1	16	Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-194840;Reactome: R-HSA-389357	"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Rho GTPase cycle";"CD28 dependent PI3K/Akt signaling"
XP_043290096.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_043284728.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043267004.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_043275007.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_043285500.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043276719.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043278909.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268599.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-165054	"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA"
XP_043268942.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation"
XP_043275545.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043280208.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_043268669.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043284140.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_043282566.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043281459.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_043269919.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_043279347.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_043271539.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_043285545.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection"
XP_043281617.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_043271532.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043288742.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043269520.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_043276307.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5578749	"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs"
XP_043280135.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043271739.1	44	KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-9634638;Reactome: R-HSA-2559580;Reactome: R-HSA-170968;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-1295596;Reactome: R-HSA-6802952;Reactome: R-HSA-881907;Reactome: R-HSA-6802946;Reactome: R-HSA-198753;Reactome: R-HSA-162658;Reactome: R-HSA-2559585;Reactome: R-HSA-5668599;Reactome: R-HSA-8940973;Reactome: R-HSA-8939211;Reactome: R-HSA-5663213;Reactome: R-HSA-9635465;Reactome: R-HSA-5674135;Reactome: R-HSA-445144;Reactome: R-HSA-5675221;Reactome: R-HSA-2029482;Reactome: R-HSA-8943724;Reactome: R-HSA-444257;Reactome: R-HSA-5674499;Reactome: R-HSA-6811558;Reactome: R-HSA-9627069;Reactome: R-HSA-450341;Reactome: R-HSA-9649948;Reactome: R-HSA-456926;Reactome: R-HSA-5654727;Reactome: R-HSA-74749;Reactome: R-HSA-375165;Reactome: R-HSA-202670;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-879415;Reactome: R-HSA-5654733;Reactome: R-HSA-112409;Reactome: R-HSA-982772;Reactome: R-HSA-2559582;Reactome: R-HSA-2871796;Reactome: R-HSA-6802948	"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Oxidative Stress Induced Senescence";"Frs2-mediated activation";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Spry regulation of FGF signaling";"Signaling by BRAF and RAF fusions";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signaling by moderate kinase activity BRAF mutants";"ERK/MAPK targets";"Golgi Cisternae Pericentriolar Stack Reorganization";"Oncogene Induced Senescence";"RHO GTPases Activate NADPH Oxidases";"RUNX2 regulates osteoblast differentiation";"ESR-mediated signaling";"RHO GTPases Activate WASPs and WAVEs";"Suppression of apoptosis";"MAP2K and MAPK activation";"Signal transduction by L1";"Negative regulation of MAPK pathway";"Regulation of actin dynamics for phagocytic cup formation";"Regulation of PTEN gene transcription";"RSK activation";"Negative feedback regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of the apoptosome activity";"Activation of the AP-1 family of transcription factors";"Signaling downstream of RAS mutants";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR2 signaling";"Signal attenuation";"NCAM signaling for neurite out-growth";"ERKs are inactivated";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR4 signaling";"RAF-independent MAPK1/3 activation";"Growth hormone receptor signaling";"Senescence-Associated Secretory Phenotype (SASP)";"FCERI mediated MAPK activation";"Signaling by high-kinase activity BRAF mutants"
XP_043285130.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_043275772.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043273745.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7328;Reactome: R-HSA-70370;Reactome: R-HSA-5609977	"Galactose metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_043280299.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043279364.1	182	Reactome: R-HSA-8941858;Reactome: R-HSA-450302;Reactome: R-HSA-174154;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-5607761;Reactome: R-HSA-2408557;Reactome: R-HSA-5610785;Reactome: R-HSA-2173796;Reactome: R-HSA-937039;Reactome: R-HSA-205043;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-8849469;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-8876493;Reactome: R-HSA-9636383;Reactome: R-HSA-3785653;Reactome: R-HSA-5357956;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-975144;Reactome: R-HSA-5610780;Reactome: R-HSA-69541;Reactome: R-HSA-201681;Reactome: R-HSA-5610783;Reactome: R-HSA-168927;Reactome: R-HSA-180534;Reactome: R-HSA-937072;Reactome: R-HSA-6782210;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-2173791;Reactome: R-HSA-202424;Reactome: R-HSA-975110;Reactome: R-HSA-2979096;Reactome: R-HSA-3322077;Reactome: R-HSA-2559585;Reactome: R-HSA-6782135;Reactome: R-HSA-192823;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-8875360;Reactome: R-HSA-5655862;Reactome: R-HSA-5689877;Reactome: R-HSA-5656121;Reactome: R-HSA-975163;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5654727;Reactome: R-HSA-110320;Reactome: R-HSA-3134975;Reactome: R-HSA-72649;Reactome: R-HSA-5357905;Reactome: R-HSA-2894862;Reactome: R-HSA-5693607;Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-174490;Reactome: R-HSA-6781823;Reactome: R-HSA-72695;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-8866654;Reactome: R-HSA-9013507;Reactome: R-HSA-5654733;Reactome: R-HSA-5689901;Reactome: R-HSA-445989;Reactome: R-HSA-5362768;Reactome: R-HSA-977225;Reactome: R-HSA-2672351;Reactome: R-HSA-2559580;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-532668;Reactome: R-HSA-168928;Reactome: R-HSA-6804757;Reactome: R-HSA-917729;Reactome: R-HSA-69481;Reactome: R-HSA-1169408;Reactome: R-HSA-9033241;Reactome: R-HSA-1169091;Reactome: R-HSA-8866652;Reactome: R-HSA-8939236;Reactome: R-HSA-912631;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-6791226;Reactome: R-HSA-5696397;Reactome: R-HSA-975957;Reactome: R-HSA-195253;Reactome: R-HSA-917937;Reactome: R-HSA-8856828;Reactome: R-HSA-450408;Reactome: R-HSA-8948747;Reactome: R-HSA-5684264;Reactome: R-HSA-975956;Reactome: R-HSA-2691232;Reactome: R-HSA-75815;Reactome: R-HSA-6804756;Reactome: R-HSA-1253288;Reactome: R-HSA-400253;Reactome: R-HSA-174048;Reactome: R-HSA-5658442;Reactome: R-HSA-901032;Reactome: R-HSA-8948751;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-1234176;Reactome: R-HSA-162588;Reactome: R-HSA-2173788;Reactome: R-HSA-5689896;Reactome: R-HSA-2644606;Reactome: R-HSA-9645460;Reactome: R-HSA-9013973;Reactome: R-HSA-8863795;Reactome: R-HSA-937041;Reactome: R-HSA-2122947;Reactome: R-HSA-209543;Reactome: R-HSA-6804760;Reactome: R-HSA-175474;Reactome: R-HSA-5358346;Reactome: R-HSA-179409;Reactome: R-HSA-382556;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-180585;Reactome: R-HSA-5654726;Reactome: R-HSA-1295596;Reactome: R-HSA-72764;Reactome: R-HSA-1358803;Reactome: R-HSA-5696400;Reactome: R-HSA-9615710;Reactome: R-HSA-8856825;Reactome: R-HSA-72706;Reactome: R-HSA-68949;Reactome: R-HSA-72689;Reactome: R-HSA-8852276;Reactome: R-HSA-5656169;Reactome: R-HSA-2173795;Reactome: R-HSA-182971;Reactome: R-HSA-9637628;Reactome: R-HSA-168638;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-156827;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-209560;Reactome: R-HSA-9604323;Reactome: R-HSA-6807004;Reactome: R-HSA-3769402;Reactome: R-HSA-1236382;Reactome: R-HSA-5668541;Reactome: R-HSA-9613829;Reactome: R-HSA-937042;Reactome: R-HSA-5696394;Reactome: R-HSA-5654732;Reactome: R-HSA-110312;Reactome: R-HSA-450321;Reactome: R-HSA-5685942;Reactome: R-HSA-9014325;Reactome: R-HSA-2122948;Reactome: R-HSA-4641263;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-5675221;Reactome: R-HSA-2565942;Reactome: R-HSA-5675482;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"Regulation of RUNX3 expression and activity";"activated TAK1 mediates p38 MAPK activation";"APC/C:Cdc20 mediated degradation of Securin";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dectin-1 mediated noncanonical NF-kB signaling";"Selenocysteine synthesis";"GLI3 is processed to GLI3R by the proteasome";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"IRAK1 recruits IKK complex";"NRIF signals cell death from the nucleus";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"InlA-mediated entry of Listeria monocytogenes into host cells";"Prevention of phagosomal-lysosomal fusion";"Myoclonic epilepsy of Lafora";"TNFR1-induced NFkappaB signaling pathway";"Neddylation";"FCERI mediated NF-kB activation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Degradation of GLI1 by the proteasome";"Stabilization of p53";"TCF dependent signaling in response to WNT";"Degradation of GLI2 by the proteasome";"TICAM1, RIP1-mediated IKK complex recruitment";"Vpu mediated degradation of CD4";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downstream TCR signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Glycogen synthesis";"Oncogene Induced Senescence";"Dual incision in TC-NER";"Viral mRNA Translation";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Translesion synthesis by POLK";"Josephin domain DUBs";"Translesion synthesis by POLI";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of FGFR2 signaling";"Translesion Synthesis by POLH";"Regulation of innate immune responses to cytosolic DNA";"Translation initiation complex formation";"Regulation of TNFR1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Processing of DNA double-strand break ends";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"Membrane binding and targetting of GAG proteins";"Formation of TC-NER Pre-Incision Complex";"Formation of the ternary complex, and subsequently, the 43S complex";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"E3 ubiquitin ligases ubiquitinate target proteins";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR4 signaling";"Metalloprotease DUBs";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Amyloid fiber formation";"Stimuli-sensing channels";"Oxidative Stress Induced Senescence";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of TP53 Degradation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"G2/M Checkpoints";"ISG15 antiviral mechanism";"Peroxisomal protein import";"Activation of NF-kappaB in B cells";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of signaling by CBL";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Major pathway of rRNA processing in the nucleolus and cytosol";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Degradation of beta-catenin by the destruction complex";"Iron uptake and transport";"Clathrin-mediated endocytosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN localization";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of TP53 Activity through Phosphorylation";"Downregulation of ERBB4 signaling";"Circadian Clock";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of RAS by GAPs";"ER Quality Control Compartment (ERQC)";"Regulation of PTEN stability and activity";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Budding and maturation of HIV virion";"Downregulation of TGF-beta receptor signaling";"Ovarian tumor domain proteases";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Alpha-protein kinase 1 signaling pathway";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of ERBB2 signaling";"IKK complex recruitment mediated by RIP1";"NOTCH1 Intracellular Domain Regulates Transcription";"p75NTR recruits signalling complexes";"Regulation of TP53 Activity through Methylation";"Assembly Of The HIV Virion";"Hedgehog ligand biogenesis";"APC-Cdc20 mediated degradation of Nek2A";"ABC-family proteins mediated transport";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Vif-mediated degradation of APOBEC3G";"Negative regulation of FGFR1 signaling";"Spry regulation of FGF signaling";"Eukaryotic Translation Termination";"Downregulation of ERBB2:ERBB3 signaling";"Dual Incision in GG-NER";"Late endosomal microautophagy";"Cargo recognition for clathrin-mediated endocytosis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Orc1 removal from chromatin";"Formation of a pool of free 40S subunits";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Termination of translesion DNA synthesis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"EGFR downregulation";"Modulation by Mtb of host immune system";"NOD1/2 Signaling Pathway";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"NF-kB is activated and signals survival";"Negative regulation of NOTCH4 signaling";"Negative regulation of MET activity";"Deactivation of the beta-catenin transactivating complex";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TNFR2 non-canonical NF-kB pathway";"Chaperone Mediated Autophagy";"IRAK2 mediated activation of TAK1 complex";"DNA Damage Recognition in GG-NER";"Negative regulation of FGFR3 signaling";"Translesion synthesis by REV1";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"HDR through Homologous Recombination (HRR)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of FZD by ubiquitination";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Negative regulation of MAPK pathway";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of necroptotic cell death";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
XP_043273845.1	7	MetaCyc: PWY-7791;MetaCyc: PWY-5698;MetaCyc: PWY-5686;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790	"UMP biosynthesis III";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"UMP biosynthesis I";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"Pyrimidine metabolism";"UMP biosynthesis II"
XP_043288472.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043270410.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_043283253.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_043266760.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043288729.1	13	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043281319.1	12	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6804756	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation"
XP_043282194.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_043286413.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043280099.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1"
XP_043270307.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043277190.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043271596.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_043281924.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_043272583.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043286612.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043282526.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_043270424.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_043279591.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043269175.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043282043.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043272995.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_043272176.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043279202.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043268357.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_043268213.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72163	"Neutrophil degranulation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway"
XP_043267946.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167158	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex"
XP_043279423.1	6	Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-5497	"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)"
XP_043275279.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043270256.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043284773.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043271420.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043276562.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043271007.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043287766.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043289110.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_043287784.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043274877.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_043267381.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043288943.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_043280329.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043268366.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043267370.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_043285791.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043272076.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043268680.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043272690.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_043272517.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043272688.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_043285499.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043275725.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043279909.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043289078.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-8852276	"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"Cilium Assembly";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_043285357.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043289564.1	18	KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Tyrosine metabolism";"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms"
XP_043285550.1	9	Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043277582.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_043269345.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398	"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway"
XP_043277801.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_043280160.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_043286182.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043272906.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events"
XP_043275010.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_043269888.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid"
XP_043269819.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043277639.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_043274743.1	10	Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111457	"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria"
XP_043280188.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733	"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Neutrophil degranulation";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_043276239.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_043271953.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043268906.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043271062.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043284285.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-5619107	"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_043268145.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043272647.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_043276508.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043269528.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043288889.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_043273431.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043268678.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_043277797.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_043285685.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043289615.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_043284841.1	5	MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_043272329.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043270665.1	24	Reactome: R-HSA-389357;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-6804757;Reactome: R-HSA-354192;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1	"CD28 dependent PI3K/Akt signaling";"RSK activation";"FCERI mediated NF-kB activation";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Activation of AKT2";"Regulation of TP53 Degradation";"Integrin signaling";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"Human cytomegalovirus infection"
XP_043266862.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043273330.1	6	Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"T cell receptor signaling pathway"
XP_043275187.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043288938.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043267325.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043271796.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043277713.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_043273232.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043269436.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_043284846.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_043272643.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043281018.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809	"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"DAG and IP3 signaling";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization"
XP_043272725.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_043280296.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043269126.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273940.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_043271824.1	11	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043279590.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043266710.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-177929	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR"
XP_043271421.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043277540.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043288697.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_043279581.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043269600.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043283435.1	7	MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;Reactome: R-HSA-70221	"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation II";"Starch degradation V";"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)"
XP_043286805.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043277403.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_043273624.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_043284789.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_043287949.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_043277165.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043281745.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043266503.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043286214.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043274404.1	13	MetaCyc: PWY-6613;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5497	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"L-histidine degradation III";"One carbon pool by folate";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)"
XP_043278739.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043272825.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043274334.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043271065.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043268754.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_043282622.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-622	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Starch biosynthesis"
XP_043284856.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_043267516.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043277528.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_043284468.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_043274446.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_043271853.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_043273033.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_043278567.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043270016.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_043274572.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_043281106.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043281195.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043274977.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_043287580.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043280948.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043280490.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043270666.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761	"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_043284336.1	10	Reactome: R-HSA-1855204;MetaCyc: PWY-6365;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6362;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;Reactome: R-HSA-983231;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6366	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Factors involved in megakaryocyte development and platelet production";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"
XP_043280105.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_043284855.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_043278023.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043272691.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression"
XP_043278529.1	11	Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling"
XP_043273716.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043275693.1	57	Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768	"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neutrophil degranulation";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_043268266.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_043266670.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_043278931.1	10	MetaCyc: PWY-6369;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191	"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus"
XP_043268077.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043274617.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043290175.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043279791.1	7	MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Purine metabolism";"Adenine salvage";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Glyphosate degradation III"
XP_043280220.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043284868.1	5	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_043287601.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_043278884.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043266765.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043279920.1	10	MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757	"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Metabolism of folate and pterines"
XP_043280856.1	19	Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8856828	"VLDL assembly";"Chylomicron clearance";"VLDL clearance";"Retinoid metabolism and transport";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL clearance";"Chylomicron assembly";"Platelet sensitization by LDL";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis"
XP_043274673.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043283942.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043287251.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-191859	"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"snRNP Assembly"
XP_043284613.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_043286611.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043272091.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043276130.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_043269981.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530	"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_043289048.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043276862.1	7	MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456	"L-phenylalanine degradation V";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria"
XP_043283816.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination"
XP_043288934.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043279843.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_043284658.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043275208.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043277255.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043287109.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C"
XP_043276756.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043279045.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043280125.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043283312.1	17	Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_043287403.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043287542.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043275788.1	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;MetaCyc: PWY-4702;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_043268019.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043279539.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_043281252.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043275640.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_043283795.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"MHC class II antigen presentation";"Glycosphingolipid metabolism"
XP_043276775.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs"
XP_043279109.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_043281111.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043273581.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_043269141.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043273634.1	12	MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5857	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_043269081.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_043285383.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043277960.1	22	KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7728;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-7727;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-5353	"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"
XP_043273617.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_043269545.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043273633.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-7230	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_043271671.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043284603.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928	"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"HS-GAG biosynthesis"
XP_043270359.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
XP_043279637.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043288637.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043272632.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_043273234.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_043274073.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_043276398.1	3	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_043281065.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043273535.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043270224.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043282355.1	12	MetaCyc: PWY-5132;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1	"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes"
XP_043281048.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_043271457.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043274263.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043272189.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043288741.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043267286.1	4	Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741	"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043287207.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_043270366.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043272361.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221	"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis"
XP_043272710.1	4	KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-6823;MetaCyc: PWY-7887	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_043277541.1	5	Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis"
XP_043276643.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043270607.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043273541.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_043268985.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939236	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_043277404.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_043279723.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043286458.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043272273.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_043283404.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043285910.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_043279120.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043267537.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_043267087.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043289418.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_043272150.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043288656.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_043289824.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043275174.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043275349.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043282967.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043289674.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_043269794.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043272351.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066	"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_043266455.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_043290103.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043267834.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_043271412.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043283771.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043281980.1	3	Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459	"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_043285129.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_043285861.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_043281094.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043267873.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043289419.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_043277201.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043289113.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043276017.1	12	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Meiotic recombination"
XP_043284249.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043282930.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043272962.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_043277986.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043267409.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043267530.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043282660.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043278912.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043268683.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043282910.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043282859.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_043287122.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043274406.1	13	MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-7909;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"One carbon pool by folate"
XP_043288962.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043284004.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043280309.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043282184.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043285265.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043272968.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_043284608.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043273970.1	14	Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043271413.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043268997.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_043269263.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043289905.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043273722.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695	"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation"
XP_043286357.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_043270221.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_043269880.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043274972.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043283881.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043272844.1	52	Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-73779	"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"mRNA Capping";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043277517.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043284887.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043271066.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043280834.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_043270047.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_043285918.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043286220.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043284817.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex"
XP_043282363.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043272875.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043278054.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043269115.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_043270964.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043272658.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_043282611.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043275529.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043274439.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043277700.1	3	KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574;MetaCyc: PWY-7426	"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_043285355.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043286610.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043274468.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043277717.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_043277896.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_043280808.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043279975.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043274196.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_043274195.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043279792.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-7807;MetaCyc: PWY-6610;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805	"Neutrophil degranulation";"Adenine and adenosine salvage II";"Glyphosate degradation III";"Adenine salvage";"Purine salvage";"Purine metabolism";"(aminomethyl)phosphonate degradation"
XP_043271283.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043277506.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043268585.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043285111.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_043287626.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_043275034.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043283043.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043269544.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043275992.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_043272016.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_043268231.1	3	Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_043288186.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043289895.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_043290185.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_043282596.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043280300.1	7	KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;MetaCyc: PWY-7980	"Photosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"ATP biosynthesis"
XP_043269884.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043274577.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_043271046.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043282817.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043272897.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion"
XP_043277853.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043275055.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_043284864.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043282730.1	6	Reactome: R-HSA-196819;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6907;MetaCyc: PWY-6898	"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III"
XP_043283085.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_043270009.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043289348.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043283059.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_043287740.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043270519.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043275923.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043269350.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Cilium Assembly";"Aggrephagy";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Kinesins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_043283066.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_043280567.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043287290.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043285608.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043269214.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043288883.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043271527.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043283723.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_043271365.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_043280966.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_043289606.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043269301.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043279652.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400	"Energy dependent regulation of mTOR by LKB1-AMPK";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_043273023.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_043273096.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_043273465.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043273396.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043274443.1	6	Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110362	"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair"
XP_043272571.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043283898.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_043271033.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837	"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation"
XP_043266745.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_043287288.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043280760.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence"
XP_043286782.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043269086.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_043267118.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043285820.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway"
XP_043270829.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_043281093.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043279023.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043273551.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043272232.1	29	Reactome: R-HSA-3108214;Reactome: R-HSA-5656121;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-3371511;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-5693616	"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLI";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"HSF1 activation";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043269687.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043285688.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_043272650.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade"
XP_043289593.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043272786.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2	"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Taurine and hypotaurine metabolism"
XP_043286757.1	5	MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821	"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification"
XP_043287061.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043273676.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043284083.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_043275797.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043279338.1	3	Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation"
XP_043270004.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis"
XP_043266722.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_043274164.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_043286402.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043287603.1	9	Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"PLC beta mediated events";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_043283339.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_043267248.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_043286466.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_043281727.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_043286064.1	17	Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-1834949;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-3270619;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565	"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Cytosolic sensors of pathogen-associated DNA";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"IRF3-mediated induction of type I IFN";"Meiotic recombination";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043266888.1	20	Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-3371571	"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Macroautophagy";"mTOR signaling pathway";"mTOR signalling";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"HSF1-dependent transactivation"
XP_043267358.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
XP_043267974.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043289812.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_043278956.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043285967.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_043288999.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-1169408	"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism"
XP_043276273.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043288287.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043289584.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043274229.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_043278062.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_043266579.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043275776.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043280971.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_043285875.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043288984.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_043281115.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043271629.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043278349.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_043285692.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043276832.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"mTOR signaling pathway"
XP_043271676.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_043280284.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_043281977.1	3	Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206	"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha"
XP_043278840.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043278856.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043283940.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043268317.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_043282247.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043271873.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043273533.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-432722	"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis"
XP_043287827.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_043281732.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043287455.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_043274074.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_043274566.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043289846.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_043274194.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_043278666.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017	"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_043277887.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_043284730.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome"
XP_043281672.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_043284583.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_043275620.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043268976.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043275009.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_043282180.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043281814.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_043273059.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043288738.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273752.1	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_043272299.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043272845.1	52	Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-167243;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73863;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-5250924;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167152	"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Termination";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"mRNA Capping";"HIV Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_043273648.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813	"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids"
XP_043267265.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043280820.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043274879.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_043289216.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_043278233.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_043272311.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043270730.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043283071.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_043274233.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_043283988.1	11	Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_043266401.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043289388.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043271017.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043266777.1	12	MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_043280343.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_043288966.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043274806.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043273332.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043271693.1	13	KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5538	"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI"
XP_043273649.1	11	Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-68962	"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex"
XP_043276269.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043285110.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_043285387.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043268340.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_043275352.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043272337.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043280039.1	11	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043280568.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043280315.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_043282066.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043273235.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043283862.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_043288982.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043284198.1	5	Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity"
XP_043277322.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_043273095.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_043273750.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_043289103.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972	"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_043272358.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_043279192.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043274964.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_043286435.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279	"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_043285364.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043285542.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043284704.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938	"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)"
XP_043268935.1	5	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
XP_043286853.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis"
XP_043270352.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_043286142.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043289300.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_043267367.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_043274797.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_043272892.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_043273911.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_043283612.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_043288037.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043288407.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_043272663.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis"
XP_043276397.1	5	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism"
XP_043285321.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_043276740.1	13	Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919	"ECM proteoglycans";"NCAM1 interactions";"Extracellular matrix organization";"Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Collagen chain trimerization";"Collagen degradation";"Signaling by PDGF";"Integrin cell surface interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils"
XP_043276510.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043289980.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043273718.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043276549.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_043269796.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043275644.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043281456.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043285075.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_043275600.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043273842.1	8	MetaCyc: PWY-5154;MetaCyc: PWY-5;MetaCyc: PWY-7400;MetaCyc: PWY-4983;MetaCyc: PWY-4984;KEGG: 00220+4.3.2.1;Reactome: R-HSA-70635;KEGG: 00250+4.3.2.1	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Arginine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism"
XP_043285964.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_043279828.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043273956.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043268346.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_043282178.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043272878.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_043274214.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_043275652.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_043281937.1	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_043282314.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043283645.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043277113.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043275087.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043274729.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_043287427.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043266787.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_043288902.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043273303.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043278762.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_043269950.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043277996.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_043271289.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043275739.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043279773.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043268384.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043288470.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043272434.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043279689.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043289775.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043285451.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_043270882.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_043283573.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043283049.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_043275997.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043275765.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043269798.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043271830.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_043276112.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-6811434	"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Kinesins";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Cilium Assembly";"Aggrephagy";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043288085.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273980.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043272409.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043275261.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043267505.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"
XP_043277990.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043273613.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043269156.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation"
XP_043284186.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043282063.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043285976.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043279200.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043279414.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_043289412.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_043286180.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043279198.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043284776.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043287630.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_043286011.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043273702.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_043281205.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043275121.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043283064.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_043268953.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043275435.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_043280793.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043278608.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_043279954.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_043284136.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_043283387.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043283050.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043274445.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73930	"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_043282916.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_043275469.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_043285776.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043282318.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043271522.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043271505.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043272411.1	19	Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938	"Retinoid metabolism and transport";"LDL remodeling";"Chylomicron clearance";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"VLDL assembly";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"LDL clearance";"Regulation of TLR by endogenous ligand"
XP_043280474.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043272944.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043283327.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043269059.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_043269155.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843	"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation"
XP_043271719.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins"
XP_043271521.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_043273102.1	8	KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043280669.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043278386.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043281238.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043268305.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_043283712.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043273887.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043272154.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043274440.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043282077.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043287049.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_043281221.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043286178.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043284001.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043273922.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043284571.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043271127.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043288645.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043276451.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043275057.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_043288479.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043289722.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_043278384.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043280560.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043275137.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_043274914.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043270755.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043267280.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_043283976.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_043286380.1	12	KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9	"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Glycerolipid metabolism"
XP_043266669.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_043289590.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043275401.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043272303.1	11	Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948	"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_043289774.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043272652.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_043269975.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043281138.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043267522.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043280850.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043280762.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585	"Ca2+ pathway";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence"
XP_043268869.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043285884.1	6	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_043286309.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043280382.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_043286006.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043284006.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043287223.1	4	Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043283362.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043284861.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043268555.1	10	Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043285191.1	4	Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_043278186.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043284606.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043289511.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_043280452.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043277743.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043275112.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043266879.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043278680.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043289296.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_043281966.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-9645722;Reactome: R-HSA-140837	"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation"
XP_043267053.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5870	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_043277320.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_043271440.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043277196.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043268586.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_043270025.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043273920.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043288932.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043270007.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_043288941.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043273864.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043278033.1	11	MetaCyc: PWY-6352;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;Reactome: R-HSA-109704;Reactome: R-HSA-1660499;Reactome: R-HSA-168138;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137	"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"Synthesis of PIPs at the plasma membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system"
XP_043272199.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043267911.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814	"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes"
XP_043278994.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552	"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Signaling by Leptin"
XP_043281133.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043290019.1	40	Reactome: R-HSA-5578749;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-76042	"Transcriptional regulation by small RNAs";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"HIV Transcription Initiation";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_043270265.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043281871.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_043268484.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278855.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043267569.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043268219.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_043285714.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043281054.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043276564.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_043287254.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-168276	"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways"
XP_043286452.1	27	Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-191859;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-975957;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-72165;Reactome: R-HSA-77595;Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"snRNP Assembly";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Minor Pathway";"Processing of Intronless Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043280314.1	8	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-437239	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Recycling pathway of L1"
XP_043276767.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_043270388.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_043268839.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_043267567.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043280096.1	1	Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH2"
XP_043268023.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043280053.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043284882.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043277583.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043281807.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043286453.1	11	MetaCyc: PWY-6964;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963	"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I"
XP_043288220.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043281114.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043279713.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043284663.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043270127.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_043270721.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275729.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043269893.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"Formation of the beta-catenin:TCF transactivating complex";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_043277069.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_043286140.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043269788.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043269870.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_043273217.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_043285367.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043278459.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6664;MetaCyc: PWY-2301;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis"
XP_043273165.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695	"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_043276223.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043272077.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_043273434.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043279716.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043272113.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043276107.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_043289330.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043274272.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043278055.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_043274757.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_043279824.1	4	Reactome: R-HSA-391160;Reactome: R-HSA-216083;Reactome: R-HSA-202733;Reactome: R-HSA-6798695	"Signal regulatory protein family interactions";"Integrin cell surface interactions";"Cell surface interactions at the vascular wall";"Neutrophil degranulation"
XP_043279173.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043277791.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_043283987.1	60	KEGG: 00627+4.2.1.17;KEGG: 00720+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7654;MetaCyc: PWY-6863;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7778;Reactome: R-HSA-77346;MetaCyc: PWY-7094;Reactome: R-HSA-1482798;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;MetaCyc: PWY-5177;Reactome: R-HSA-77305;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;MetaCyc: PWY-5789;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00281+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7007;MetaCyc: PWY-6435;MetaCyc: PWY-6946;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7656;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17	"Aminobenzoate degradation";"Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Fermentation to 2-methylbutanoate";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid elongation";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"2-methylpropene degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid salvage";"Acyl chain remodeling of CL";"Carbon fixation pathways in prokaryotes";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Glutaryl-coa degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoate degradation";"Fatty acid elongation";"Fatty acid beta-oxidation II (plant peroxisome)";"Geraniol degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Lysine degradation";"Androstenedione degradation";"Butanoate metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Caprolactam degradation";"Benzoate degradation";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"beta-Alanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Spodoptera littoralis pheromone biosynthesis";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Tryptophan metabolism";"Limonene and pinene degradation"
XP_043267237.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_043279576.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_043275546.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043289440.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_043285437.1	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_043283296.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043284572.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043280967.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_043278718.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043280132.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043273385.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043282441.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_043273797.1	3	Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import"
XP_043275601.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_043268937.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_043276757.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284192.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_043269962.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_043275742.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043273582.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_043270858.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043275527.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043286844.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043270115.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043267882.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043278385.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043274463.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043267788.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043270672.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043285655.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043280578.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043285767.1	8	MetaCyc: PWY-8086;MetaCyc: PWY-6901;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Propanoate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_043289702.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_043282207.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652	"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_043284263.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043283622.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_043272686.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_043270821.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043268429.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043279588.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043287653.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_043273606.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043273230.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_043276171.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043283402.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_043272343.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043287534.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_043283011.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_043266673.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_043271659.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043287034.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_043285627.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_043286802.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043273971.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043282715.1	9	MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663	"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_043281528.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043277886.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_043279832.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043288288.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043288084.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043282927.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK"
XP_043274068.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043280889.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043282257.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560	"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II"
XP_043280895.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517	"cGMP effects";"Ca2+ pathway";"Rap1 signalling"
XP_043272163.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_043271304.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043288273.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278871.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_043281027.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-112043	"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events"
XP_043276990.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_043289089.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_043283286.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043270116.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_043272989.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043275839.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_043272161.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043278563.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043283503.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043282213.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043274133.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5467340	"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"RAF activation";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex"
XP_043267366.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_043284036.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043279542.1	17	KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-4381	"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_043284080.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043286854.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_043268205.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043289038.1	5	MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757	"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines"
XP_043280741.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043281023.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809	"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Ca2+ pathway";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"FCERI mediated Ca+2 mobilization"
XP_043286613.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043281057.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043278387.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043276927.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_043279607.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043276013.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043290188.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043283582.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043275724.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043278557.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043284607.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043275779.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043280233.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043290187.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_043280270.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_043279210.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_043282143.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043283200.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043276111.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043279190.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043276559.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043271585.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_043289646.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283054.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043278726.1	4	Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50	"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism"
XP_043284665.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043274707.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043281955.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-8953750	"Neutrophil degranulation";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6"
XP_043268708.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043272503.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043267124.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043289944.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_043273382.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043272514.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043274660.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_043276602.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_043283078.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536	"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_043285404.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043274912.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043280278.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_043267532.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-174411	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere"
XP_043271736.1	7	KEGG: 00630+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;MetaCyc: PWY-6969;MetaCyc: PWY-7854;MetaCyc: PWY-7294	"Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV";"Chitin degradation to ethanol";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"D-xylose degradation IV"
XP_043280186.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091	"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells"
XP_043278959.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_043279955.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_043267254.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283034.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_043278060.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-450520;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_043276671.1	15	Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178	"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_043280495.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043270832.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_043286088.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_043267570.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_043266716.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation"
XP_043269542.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043280547.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_043289605.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043290146.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043266386.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_043288274.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_043272907.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_043282188.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043286405.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043278925.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_043279888.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043289861.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117	"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis"
XP_043278550.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340	"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation"
XP_043277094.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043287284.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043284790.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043276611.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043281017.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485	"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis"
XP_043269386.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_043286173.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_043282819.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043288946.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043273841.1	10	KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-5022;Reactome: R-HSA-916853;MetaCyc: PWY-6537;MetaCyc: PWY-4321	"beta-Alanine metabolism";"4-aminobutanoate degradation I";"Butanoate metabolism";"4-aminobutanoate degradation III";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism";"4-aminobutanoate degradation V";"Degradation of GABA";"4-aminobutanoate degradation II";"L-glutamate degradation IV"
XP_043274758.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_043286038.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043268760.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043274778.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043280734.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043268160.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_043280356.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_043271544.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9610379	"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events"
XP_043274422.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I"
XP_043277177.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043278903.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043278709.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043272371.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_043268554.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043275843.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043274751.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy"
XP_043268247.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043278655.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_043270605.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043267752.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_043268996.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_043284590.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043273429.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043284115.1	10	MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism"
XP_043275521.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_043276265.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043282989.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043267064.1	1	Reactome: R-HSA-446193	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_043289364.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043272644.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043279413.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_043279865.1	2	Reactome: R-HSA-4549349;Reactome: R-HSA-446193	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_043273256.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043276444.1	10	MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I"
XP_043266874.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_043280894.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043268078.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043269179.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043289515.1	4	Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_043279199.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043269613.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_043268035.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_043276226.1	6	Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_043278485.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043272363.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221	"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis"
XP_043277523.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043289637.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043271652.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043275457.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043285360.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043277765.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043272567.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043268843.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_043278339.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043280165.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043272815.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_043266498.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043277394.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_043276241.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043274489.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism"
XP_043275507.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_043278735.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043280728.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_043289792.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043268596.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport"
XP_043278743.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043286332.1	10	MetaCyc: PWY-5691;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695	"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Purine metabolism";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation"
XP_043280551.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043273263.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043289818.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043286426.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043274206.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_043281657.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_043283386.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043269063.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043281053.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043270253.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043278991.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043269037.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043268021.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043287009.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_043268452.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"RORA activates gene expression";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_043274575.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_043266483.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_043288002.1	1	Reactome: R-HSA-419771	"Opsins"
XP_043275731.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_043286043.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_043274571.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043285369.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043280559.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_043284566.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043267546.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_043284195.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_043282361.1	14	MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_043288799.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043289463.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043285899.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_043277898.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism"
XP_043276369.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043276381.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-7782	"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis"
XP_043279667.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043281849.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043280974.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_043267391.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043279221.1	6	Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-2151201	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis"
XP_043277491.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_043267568.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043266389.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043271391.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043280893.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043274510.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043275487.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_043284431.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_043288795.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043270073.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_043282758.1	14	MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation"
XP_043279962.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043287206.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis"
XP_043278958.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_043274598.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_043279502.1	17	MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780	"Glyoxylate assimilation";"Pyruvate metabolism";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism"
XP_043280040.1	11	Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007	"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"p38MAPK events"
XP_043269058.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_043280743.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043283348.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043287406.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043280663.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043269568.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043281136.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043269054.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
XP_043287229.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-446199	"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_043274599.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions"
XP_043276764.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043272895.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_043272662.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-3371571	"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"HSF1-dependent transactivation"
XP_043278804.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273600.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043288039.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043274583.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043283204.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043276173.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043276511.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043281055.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043285838.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043272891.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion"
XP_043279510.1	17	MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression"
XP_043280905.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571	"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation"
XP_043282850.1	3	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism"
XP_043282298.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043267359.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_043281453.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043266395.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_043286322.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043278863.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_043270664.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761	"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_043272703.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_043271442.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_043289851.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043282823.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043288646.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043269517.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043269540.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_043280275.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_043279496.1	5	MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88	"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Arginine and proline metabolism"
XP_043278792.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043288890.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_043283571.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043269908.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_043276601.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-6784531	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus"
XP_043283786.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_043278156.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043277469.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_043271784.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_043280766.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585	"Ca2+ pathway";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence"
XP_043277512.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_043280456.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043286617.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043284111.1	10	KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis IV (plant cytosol)"
XP_043275627.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043279195.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043277985.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043272508.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043287300.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043273446.1	4	Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_043271875.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043279425.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_043289254.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_043272568.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043274135.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-196299	"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade"
XP_043270351.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_043281471.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043286433.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_043288636.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043272314.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_043272309.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043290140.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_043272491.1	11	Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"AURKA Activation by TPX2"
XP_043281088.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-5663	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_043276755.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273220.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043286034.1	5	Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_043277590.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043272987.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043280623.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_043275179.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043276518.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043289334.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-69017	"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6"
XP_043281879.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_043285305.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_043269205.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_043283803.1	7	KEGG: 00220+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-6922;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;Reactome: R-HSA-70635	"Arginine biosynthesis";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Arginine and proline metabolism";"Canavanine degradation";"Urea cycle"
XP_043267125.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043269337.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043283776.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_043285029.1	42	Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-912446	"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Meiotic synapsis";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Meiotic recombination"
XP_043287600.1	9	MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"PLC beta mediated events"
XP_043289369.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043286983.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_043273381.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043275785.1	7	Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_043268977.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043273450.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183	"Polymerase switching";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand"
XP_043285980.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043289509.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_043280970.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_043278227.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_043286040.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043271341.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_043277489.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043279191.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043268799.1	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_043279442.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043280763.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884	"Ca2+ pathway";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX"
XP_043266881.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745	"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_043273927.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043268818.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_043281292.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043272165.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_043282718.1	12	KEGG: 00230+6.3.3.1;MetaCyc: PWY-6121;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6277;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9;Reactome: R-HSA-73817	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Biotin transport and metabolism";"Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis"
XP_043287960.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043285317.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043272993.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043281827.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043284045.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043269236.1	18	MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7416	"Plasmalogen degradation";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_043288435.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_043283637.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_043286468.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043284575.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043279257.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043268201.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043279136.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_043272307.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043289246.1	5	MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6	"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism"
XP_043284491.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043288481.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_043268153.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043267058.1	10	KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11	"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_043280745.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_043282296.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043275522.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043269573.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043275752.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043286772.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043285405.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043276921.1	12	KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-174362;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550	"Purine metabolism";"Sulfur metabolism";"Selenate reduction";"Purine metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Sulfur metabolism";"Monobactam biosynthesis";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
XP_043288437.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_043275974.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208	"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling"
XP_043278782.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_043290161.1	8	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;KEGG: 00970+2.1.2.9;Reactome: R-HSA-2426168;Reactome: R-HSA-389661;KEGG: 00670+2.1.2.9;Reactome: R-HSA-75105	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Aminoacyl-tRNA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate metabolism and glycine degradation";"One carbon pool by folate";"Fatty acyl-CoA biosynthesis"
XP_043266414.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_043281549.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_043282144.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_043272669.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling"
XP_043281020.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809	"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Ca2+ pathway";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Ion homeostasis";"FCERI mediated Ca+2 mobilization"
XP_043275771.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043267026.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_043269907.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_043271287.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043284013.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043269137.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043288730.1	13	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097	"Thermogenesis";"Relaxin signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_043287686.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043268406.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745	"Gap junction degradation";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_043280395.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631	"MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL"
XP_043278910.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043283621.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043266880.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"LDL clearance";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"VLDLR internalisation and degradation"
XP_043274919.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043282060.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043272147.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043289858.1	9	MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7385	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)"
XP_043283406.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043268146.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043267374.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043268204.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043282382.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_043275749.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043289958.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-1989781	"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression"
XP_043273630.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_043270706.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043272112.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043280709.1	10	Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-917729	"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_043286074.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-428543;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220;Reactome: R-HSA-5627123;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-3928662	"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"Inactivation of CDC42 and RAC1";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"EGFR downregulation";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins";"RHO GTPases activate PAKs";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"EPHB-mediated forward signaling"
XP_043274400.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043283434.1	7	Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724	"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation II"
XP_043268404.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_043274215.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_043283431.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_043266923.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043277545.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_043280408.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_043283456.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043282446.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043266454.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_043285351.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043279852.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043268368.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043272991.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043267457.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043273266.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043270516.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043284578.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_043290137.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043273888.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043281936.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043266453.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_043274509.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043282623.1	6	Reactome: R-HSA-3878781;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_043278196.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_043284888.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043273537.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043269227.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043270472.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043274765.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043277655.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_043270245.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043280756.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043281539.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043277107.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_043275270.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043270877.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_043287648.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043288779.1	7	Reactome: R-HSA-8964539;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2	"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism"
XP_043269526.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043273379.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043278292.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043280549.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043268866.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043269598.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043280815.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043288428.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_043285855.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043283661.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3232118	"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors"
XP_043275867.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
XP_043283172.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043289716.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-3561	"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Choline biosynthesis III"
XP_043280811.1	7	MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation"
XP_043286731.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043290035.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043269289.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_043269901.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_043270708.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043268294.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043269233.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043286710.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043282259.1	30	Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-2564830;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Cytosolic iron-sulfur cluster assembly";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_043284081.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043272304.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043288046.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_043287232.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167243	"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_043283349.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043279449.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043274492.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_043267526.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043274213.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_043284430.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_043284181.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043289251.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_043275732.1	4	KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I"
XP_043270909.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043283870.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_043268809.1	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043285912.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_043276647.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043268371.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043273889.1	11	MetaCyc: PWY-5913;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)"
XP_043281848.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043276600.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236	"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043277380.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_043278135.1	18	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits"
XP_043280481.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043282488.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043272469.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043271291.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_043273824.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043269457.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_043271759.1	32	Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-8851708	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM"
XP_043277191.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043277475.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_043273674.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043289558.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043287705.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043273843.1	8	KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4983;MetaCyc: PWY-4984;MetaCyc: PWY-7400;MetaCyc: PWY-5;MetaCyc: PWY-5154	"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_043289253.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_043280662.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043277828.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_043287541.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043278607.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_043281109.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043286060.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling"
XP_043268871.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism"
XP_043283053.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_043280735.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_043271286.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043283974.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_043281320.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_043282890.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_043272665.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_043283721.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_043287759.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043267738.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_043290144.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00051+5.3.1.1;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-6142	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Glycerol degradation to butanol";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_043285276.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_043271762.1	32	Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167158	"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"mRNA Capping";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex"
XP_043289059.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043276119.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_043277640.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_043270050.1	9	Reactome: R-HSA-6782315;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"tRNA modification in the nucleus and cytosol";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_043282087.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043288981.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043285450.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Signaling by BRAF and RAF fusions"
XP_043274487.1	3	KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_043282586.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043269184.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043282969.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_043284014.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043268401.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043266626.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043267462.1	6	Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis"
XP_043272094.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_043283485.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043278565.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043283954.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_043281382.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043276682.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_043274851.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"COPI-mediated anterograde transport";"Neutrophil degranulation";"Interaction between L1 and Ankyrins"
XP_043278601.1	8	Reactome: R-HSA-5340588;Reactome: R-HSA-4086398;Reactome: R-HSA-373080;Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900	"RNF mutants show enhanced WNT signaling and proliferation";"Ca2+ pathway";"Class B/2 (Secretin family receptors)";"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_043281058.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043287041.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_043267832.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_043270077.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_043270817.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_043273890.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_043277188.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043283058.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_043283353.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043266839.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043278763.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_043276520.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043279530.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043271036.1	6	Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events"
XP_043284532.1	5	MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-7082;MetaCyc: PWY-3781	"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)"
XP_043267398.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043276994.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_043278605.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_043284906.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_043271141.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_043280451.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043282857.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_043277849.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043268567.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_043285829.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_043282567.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043276224.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043269080.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_043283918.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_043271302.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043269894.1	5	MetaCyc: PWY-3781;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692	"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation"
XP_043287457.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043289640.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_043268258.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_043281167.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043282913.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043279554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043277601.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043284729.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome"
XP_043268318.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_043268529.1	28	Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-3371453;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400	"Meiotic recombination";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"HSF1 activation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER"
XP_043279077.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_043280133.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043272362.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221	"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis"
XP_043277813.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_043276249.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903	"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy"
XP_043287771.1	7	Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis"
XP_043277164.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043278833.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043279111.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_043288477.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043281493.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043282176.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043268181.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5873	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_043290072.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-69017	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6"
XP_043278127.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation"
XP_043277017.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043268868.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043279918.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_043274565.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275116.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043271731.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_043267272.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_043280737.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_043281042.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_043269326.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_043284185.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_043273022.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043283187.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043283157.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_043270577.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043268789.1	4	KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis"
XP_043279017.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043274041.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275331.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression"
XP_043274761.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_043269365.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043271249.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_043281316.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043288544.1	11	Reactome: R-HSA-114604;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-389948;Reactome: R-HSA-391160;Reactome: R-HSA-909733;Reactome: R-HSA-388841;Reactome: R-HSA-432142;Reactome: R-HSA-877312;Reactome: R-HSA-512988	"GPVI-mediated activation cascade";"Regulation of IFNA signaling";"Interleukin-37 signaling";"PECAM1 interactions";"PD-1 signaling";"Signal regulatory protein family interactions";"Interferon alpha/beta signaling";"Costimulation by the CD28 family";"Platelet sensitization by LDL";"Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_043274971.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043284966.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043268490.1	4	Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_043269690.1	4	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_043275728.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043269824.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-349425	"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_043289225.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_043273978.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043289202.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_043279597.1	17	Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1	"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Fanconi Anemia Pathway";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection"
XP_043276401.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2894862	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043285982.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043272353.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-447038	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"NrCAM interactions"
XP_043272474.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_043273977.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043269302.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043281548.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_043282478.1	2	Reactome: R-HSA-352230;Reactome: R-HSA-442660	"Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters"
XP_043268295.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043283697.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043288219.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043269790.1	10	KEGG: 05165+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-9027276	"Human papillomavirus infection";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"
XP_043272880.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_043281134.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043278902.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043279558.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043288739.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043290169.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043275835.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors"
XP_043278449.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism"
XP_043269771.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_043287940.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043284678.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043270229.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_043284090.1	9	MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-70263;MetaCyc: PWY-6142	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_043268704.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043276538.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268911.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_043272370.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_043267323.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_043279772.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043287143.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043280031.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043281022.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775	"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"Ion homeostasis"
XP_043274283.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-2221	"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_043278681.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043276109.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_043285630.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043267072.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_043269032.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_043266405.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_043280297.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043273976.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043289906.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_043271460.1	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_043283493.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043283398.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043276565.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_043279662.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043283132.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043289402.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_043278393.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043268941.1	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_043283801.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051	"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis I"
XP_043281043.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_043272093.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043288974.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043282372.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043284253.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_043279840.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043268945.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation"
XP_043289438.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043289264.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_043272339.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043280981.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_043277621.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043286012.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043289591.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043278906.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043271125.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_043271037.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-5099900	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4"
XP_043268065.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043280832.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_043284355.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378	"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling"
XP_043267008.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_043274471.1	10	MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7328	"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_043278155.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043268306.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation"
XP_043273615.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_043271485.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_043288443.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_043270707.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043284850.1	5	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_043272512.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043267390.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043285682.1	5	MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_043288935.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043290086.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_043268150.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043269705.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043273433.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043273292.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_043273580.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_043285192.1	4	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_043277863.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043279418.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_043268817.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_043267150.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043279732.1	12	Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Activation of AMPK downstream of NMDARs";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043282651.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043275266.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043290061.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043273668.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_043275455.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043274266.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043267357.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_043282893.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043281241.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043272300.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_043268423.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism"
XP_043279489.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_043272348.1	12	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules"
XP_043284854.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_043283617.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_043285449.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_043282714.1	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5664	"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_043275935.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043270258.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043268707.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043281112.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043281178.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_043282634.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109	"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_043287553.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043278924.1	4	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_043274678.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_043288758.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043275777.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043277510.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_043269625.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043272277.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Signaling by Hippo"
XP_043272881.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_043288442.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_043285384.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043286801.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043274208.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_043271481.1	7	KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064;Reactome: R-HSA-71403	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Citric acid cycle (TCA cycle)"
XP_043273468.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043284470.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_043274150.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_043288185.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043271786.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043269664.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_043275029.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400	"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_043289816.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion"
XP_043269626.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043288432.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_043278843.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043278859.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043277172.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_043276216.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_043280163.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_043285983.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_043281206.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043280128.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043273632.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_043273463.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043276286.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_043277189.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043287719.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2022857	"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation"
XP_043275760.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043281139.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043272290.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_043279435.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_043275757.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043285244.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_043271434.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_043270075.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_043278126.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation"
XP_043284897.1	20	MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837	"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_043281582.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043268212.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_043276240.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_043276483.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043281597.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043277411.1	6	MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
XP_043273708.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043275357.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043279668.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043286299.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043272672.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling"
XP_043279788.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_043282776.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_043275535.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043282187.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043289301.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_043278868.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_043272175.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043283051.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043268074.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043282576.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043267949.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043287713.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043290160.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_043276766.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043281759.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043288973.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043270847.1	179	Reactome: R-HSA-450302;Reactome: R-HSA-110314;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-6781827;Reactome: R-HSA-8941858;Reactome: R-HSA-937039;Reactome: R-HSA-2173796;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-205043;Reactome: R-HSA-5610785;Reactome: R-HSA-8849469;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-9636383;Reactome: R-HSA-8876493;Reactome: R-HSA-3785653;Reactome: R-HSA-2408557;Reactome: R-HSA-180534;Reactome: R-HSA-168927;Reactome: R-HSA-937072;Reactome: R-HSA-9633012;Reactome: R-HSA-6782210;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5357956;Reactome: R-HSA-5610780;Reactome: R-HSA-975144;Reactome: R-HSA-69541;Reactome: R-HSA-5610783;Reactome: R-HSA-201681;Reactome: R-HSA-9020702;Reactome: R-HSA-192823;Reactome: R-HSA-8875360;Reactome: R-HSA-983168;Reactome: R-HSA-5655862;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-2979096;Reactome: R-HSA-975110;Reactome: R-HSA-202424;Reactome: R-HSA-2173791;Reactome: R-HSA-3322077;Reactome: R-HSA-2559585;Reactome: R-HSA-6782135;Reactome: R-HSA-5654727;Reactome: R-HSA-110320;Reactome: R-HSA-2894862;Reactome: R-HSA-5357905;Reactome: R-HSA-3134975;Reactome: R-HSA-5693607;Reactome: R-HSA-5689877;Reactome: R-HSA-8854050;Reactome: R-HSA-975163;Reactome: R-HSA-5656121;Reactome: R-HSA-349425;Reactome: R-HSA-6781823;Reactome: R-HSA-174490;Reactome: R-HSA-174184;Reactome: R-HSA-9013507;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-5654733;Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-445989;Reactome: R-HSA-5362768;Reactome: R-HSA-5689901;Reactome: R-HSA-2672351;Reactome: R-HSA-977225;Reactome: R-HSA-156902;Reactome: R-HSA-2559580;Reactome: R-HSA-8866652;Reactome: R-HSA-8939236;Reactome: R-HSA-912631;Reactome: R-HSA-4641258;Reactome: R-HSA-5696397;Reactome: R-HSA-6791226;Reactome: R-HSA-187577;Reactome: R-HSA-532668;Reactome: R-HSA-168928;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-9033241;Reactome: R-HSA-1169408;Reactome: R-HSA-917729;Reactome: R-HSA-6804757;Reactome: R-HSA-1169091;Reactome: R-HSA-975956;Reactome: R-HSA-2691232;Reactome: R-HSA-75815;Reactome: R-HSA-174048;Reactome: R-HSA-400253;Reactome: R-HSA-1253288;Reactome: R-HSA-6804756;Reactome: R-HSA-901032;Reactome: R-HSA-5658442;Reactome: R-HSA-917937;Reactome: R-HSA-195253;Reactome: R-HSA-975957;Reactome: R-HSA-8856828;Reactome: R-HSA-450408;Reactome: R-HSA-5684264;Reactome: R-HSA-8948747;Reactome: R-HSA-2644606;Reactome: R-HSA-9013973;Reactome: R-HSA-9645460;Reactome: R-HSA-8863795;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-8948751;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-162588;Reactome: R-HSA-1234176;Reactome: R-HSA-5689896;Reactome: R-HSA-2173788;Reactome: R-HSA-69231;Reactome: R-HSA-180585;Reactome: R-HSA-72764;Reactome: R-HSA-1295596;Reactome: R-HSA-5654726;Reactome: R-HSA-1358803;Reactome: R-HSA-209543;Reactome: R-HSA-2122947;Reactome: R-HSA-937041;Reactome: R-HSA-5358346;Reactome: R-HSA-6804760;Reactome: R-HSA-175474;Reactome: R-HSA-179409;Reactome: R-HSA-382556;Reactome: R-HSA-5693565;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-72689;Reactome: R-HSA-9615710;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-72706;Reactome: R-HSA-9637628;Reactome: R-HSA-168638;Reactome: R-HSA-1799339;Reactome: R-HSA-5656169;Reactome: R-HSA-2173795;Reactome: R-HSA-182971;Reactome: R-HSA-3769402;Reactome: R-HSA-6807004;Reactome: R-HSA-9604323;Reactome: R-HSA-1236382;Reactome: R-HSA-9613829;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-156827;Reactome: R-HSA-68827;Reactome: R-HSA-209560;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5696394;Reactome: R-HSA-110312;Reactome: R-HSA-5654732;Reactome: R-HSA-937042;Reactome: R-HSA-4641263;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-5675221;Reactome: R-HSA-5675482;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5685942;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-2122948	"activated TAK1 mediates p38 MAPK activation";"Recognition of DNA damage by PCNA-containing replication complex";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of RUNX3 expression and activity";"IRAK1 recruits IKK complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"NRIF signals cell death from the nucleus";"GLI3 is processed to GLI3R by the proteasome";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Prevention of phagosomal-lysosomal fusion";"InlA-mediated entry of Listeria monocytogenes into host cells";"Myoclonic epilepsy of Lafora";"Selenocysteine synthesis";"Vpu mediated degradation of CD4";"TICAM1, RIP1-mediated IKK complex recruitment";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FCERI mediated NF-kB activation";"Neddylation";"TNFR1-induced NFkappaB signaling pathway";"Degradation of GLI1 by the proteasome";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Stabilization of p53";"Degradation of GLI2 by the proteasome";"TCF dependent signaling in response to WNT";"Interleukin-1 signaling";"Viral mRNA Translation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion synthesis by POLK";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Downstream TCR signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Glycogen synthesis";"Oncogene Induced Senescence";"Dual incision in TC-NER";"Negative regulation of FGFR2 signaling";"Translesion Synthesis by POLH";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of TNFR1 signaling";"Regulation of innate immune responses to cytosolic DNA";"Processing of DNA double-strand break ends";"Josephin domain DUBs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by POLI";"Autodegradation of the E3 ubiquitin ligase COP1";"Formation of TC-NER Pre-Incision Complex";"Membrane binding and targetting of GAG proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"Negative regulation of FGFR4 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Metalloprotease DUBs";"Stimuli-sensing channels";"Amyloid fiber formation";"Peptide chain elongation";"Oxidative Stress Induced Senescence";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of signaling by CBL";"Degradation of DVL";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF(Skp2)-mediated degradation of p27/p21";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Peroxisomal protein import";"ISG15 antiviral mechanism";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of TP53 Degradation";"Activation of NF-kappaB in B cells";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Cyclin B";"Circadian Clock";"Downregulation of ERBB4 signaling";"Regulation of TP53 Activity through Phosphorylation";"ER Quality Control Compartment (ERQC)";"Regulation of RAS by GAPs";"Iron uptake and transport";"Degradation of beta-catenin by the destruction complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Clathrin-mediated endocytosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PTEN localization";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TICAM1-dependent activation of IRF3/IRF7";"Alpha-protein kinase 1 signaling pathway";"Downregulation of ERBB2 signaling";"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Regulation of PTEN stability and activity";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Budding and maturation of HIV virion";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ovarian tumor domain proteases";"Downregulation of TGF-beta receptor signaling";"Cyclin D associated events in G1";"Vif-mediated degradation of APOBEC3G";"Eukaryotic Translation Termination";"Spry regulation of FGF signaling";"Negative regulation of FGFR1 signaling";"Downregulation of ERBB2:ERBB3 signaling";"p75NTR recruits signalling complexes";"NOTCH1 Intracellular Domain Regulates Transcription";"IKK complex recruitment mediated by RIP1";"Hedgehog ligand biogenesis";"Regulation of TP53 Activity through Methylation";"Assembly Of The HIV Virion";"APC-Cdc20 mediated degradation of Nek2A";"ABC-family proteins mediated transport";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of a pool of free 40S subunits";"Late endosomal microautophagy";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Modulation by Mtb of host immune system";"NOD1/2 Signaling Pathway";"SRP-dependent cotranslational protein targeting to membrane";"Termination of translesion DNA synthesis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"EGFR downregulation";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of MET activity";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Chaperone Mediated Autophagy";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"L13a-mediated translational silencing of Ceruloplasmin expression";"CDT1 association with the CDC6:ORC:origin complex";"NF-kB is activated and signals survival";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"DNA Damage Recognition in GG-NER";"Translesion synthesis by REV1";"Negative regulation of FGFR3 signaling";"IRAK2 mediated activation of TAK1 complex";"Regulation of FZD by ubiquitination";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of MAPK pathway";"Regulation of necroptotic cell death";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"HDR through Homologous Recombination (HRR)";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_043269902.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_043281300.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_043280824.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043276509.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043279964.1	5	MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Purine metabolism"
XP_043284095.1	14	MetaCyc: PWY-6453;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-8053	"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"Anandamide biosynthesis II"
XP_043273577.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-381676	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_043267284.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043271871.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043279721.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043279563.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_043282474.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_043280577.1	40	Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-5578749	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"HIV Transcription Initiation";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Transcriptional regulation by small RNAs"
XP_043266639.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_043285012.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043277897.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_043271004.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12	"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms"
XP_043270422.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_043266556.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_043279849.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043278059.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-450520	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA"
XP_043282006.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_043278146.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043289894.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_043270916.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043281208.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_043268193.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_043274965.1	11	Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-6782135	"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"DNA replication initiation";"Dual incision in TC-NER"
XP_043280670.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043270824.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_043269594.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858	"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Neddylation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity"
XP_043275092.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043274808.1	10	MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6886	"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)"
XP_043280829.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_043287745.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043288661.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278141.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043275999.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_043275146.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_043282383.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_043288844.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_043284749.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1234176	"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_043288580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043272990.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043285936.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043280617.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_043271525.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043280563.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043289047.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043287744.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043272912.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_043267407.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043286803.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043268293.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043283070.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_043269296.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043272655.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-936837	"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF activation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases"
XP_043288378.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_043268178.1	12	MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;MetaCyc: PWY-5856	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_043276370.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043271259.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_043267015.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_043287752.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_043272660.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673000	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF activation"
XP_043282324.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_043284764.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043281098.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043270012.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043284609.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043287227.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_043288737.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043277093.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043268073.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_043279844.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328	"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_043277697.1	3	KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574;MetaCyc: PWY-7426	"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_043282101.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043274165.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_043270270.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043281283.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043280359.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043280222.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043289441.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_043279679.1	9	MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation III (Serratia)"
XP_043275599.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_043279836.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043273672.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278930.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6369;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_043276915.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_043285425.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043275579.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043287278.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043280492.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043271418.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043284793.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043278839.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043272836.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-163560	"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism"
XP_043279931.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043270823.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043270162.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_043278238.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043274913.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043268269.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_043284819.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition"
XP_043286576.1	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_043275984.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_043272657.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_043282548.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_043288572.1	11	Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-389948;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-388841;Reactome: R-HSA-909733;Reactome: R-HSA-391160	"Regulation of IFNA signaling";"Interleukin-37 signaling";"PECAM1 interactions";"PD-1 signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"Costimulation by the CD28 family";"Interferon alpha/beta signaling";"Signal regulatory protein family interactions"
XP_043273552.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043268017.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043269300.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043269247.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8943723	"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation"
XP_043277604.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_043276351.1	14	MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453	"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis"
XP_043279119.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043268236.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_043273061.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043279963.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043271663.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_043267283.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043287396.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043287301.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043268949.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_043284657.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_043269490.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043279419.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_043283516.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043271099.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043272653.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-3371571	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"HSF1-dependent transactivation"
XP_043275260.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043267515.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"
XP_043268668.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043276382.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7411;Reactome: R-HSA-1483166	"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA"
XP_043290134.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043267836.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_043276958.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043278045.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_043280108.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043285335.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043266467.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043273164.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_043286721.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_043266640.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043279273.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_043274128.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_043281968.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043285190.1	4	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_043272865.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043279610.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_043279494.1	17	MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744	"Candicidin biosynthesis";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"Pyruvate metabolism";"Glyoxylate assimilation"
XP_043280838.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_043271437.1	12	Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948	"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_043270090.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043284476.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043283451.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_043284622.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_043268618.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043289212.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043279833.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043290171.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043289295.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_043282980.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_043267350.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_043281203.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043280388.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043274827.1	6	KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124	"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II"
XP_043275868.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043287043.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_043275130.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043287655.1	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4	"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Synthesis of PA";"Ether lipid metabolism"
XP_043285985.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_043279344.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043279657.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043275800.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation"
XP_043275520.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043282540.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_043281627.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043286629.1	7	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_043279846.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_043275095.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043269124.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_043272867.1	2	KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_043273825.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043269489.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043273703.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_043280100.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1"
XP_043280769.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_043267203.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_043272392.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043271081.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043288136.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_043267363.1	14	KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5078;MetaCyc: PWY-5103;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5104;Reactome: R-HSA-70895;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057	"Cysteine and methionine metabolism";"L-leucine degradation III";"L-isoleucine degradation II";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine degradation";"L-valine degradation II"
XP_043266411.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_043280792.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043286941.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043284267.1	8	Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750	"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6"
XP_043287464.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_043286036.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972	"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_043272255.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043267361.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_043288467.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_043274621.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043266712.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043276353.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782	"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis"
XP_043272258.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043282183.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043274269.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_043274713.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043273260.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043288685.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_043288945.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_043278708.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043280826.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043276400.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_043287054.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043268816.1	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_043266898.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043289860.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043282895.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043267430.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043279845.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_043269602.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043267145.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_043290172.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043270600.1	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783	"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome"
XP_043286172.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_043270996.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043279761.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043289096.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_043288933.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043283468.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043270765.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043276268.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043289397.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_043280807.1	7	MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7586	"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_043276847.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_043272570.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043281074.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043272651.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9649948	"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants"
XP_043270670.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043273627.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_043273299.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043289549.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_043272942.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_043269123.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_043271825.1	11	MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Purine metabolism"
XP_043268955.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043267433.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043273466.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043276546.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_043273426.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7338	"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_043286463.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043277658.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043268380.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043279686.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_043283160.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Collagen degradation";"Collagen chain trimerization"
XP_043278489.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043278336.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043275879.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation"
XP_043281651.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043274918.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043269342.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043281166.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043279534.1	17	KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;MetaCyc: PWY-4381;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722	"Pyruvate metabolism";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"Candicidin biosynthesis"
XP_043275470.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_043281032.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_043277202.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043280774.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043283384.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_043273097.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_043271351.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948	"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants"
XP_043276464.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_043280600.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_043280733.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_043287639.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043285514.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_043277763.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043281200.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_043281110.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043273602.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043271872.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043281070.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043270267.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043267477.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_043275008.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_043271414.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043268597.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043286671.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_043270180.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_043286781.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Gap junction assembly";"Cilium Assembly";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043276271.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043276408.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043286487.1	7	Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_043274132.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_043272780.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043273614.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043279834.1	18	MetaCyc: PWY-5046;KEGG: 00020+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-71064;KEGG: 00380+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00010+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00640+1.8.1.4	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Lysine catabolism";"Tryptophan metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Valine, leucine and isoleucine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine, serine and threonine metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism"
XP_043270713.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043281758.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043289634.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043279739.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_043283385.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043273570.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043281824.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_043279527.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043271517.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_043266742.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043288376.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_043274285.1	15	MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484	"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_043266449.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043268898.1	17	Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C"
XP_043279134.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_043271876.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043285181.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043271734.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_043269653.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_043284000.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_043281047.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043287874.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043271506.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043274441.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043288882.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_043276768.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_043272832.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043275058.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043287739.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043274303.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_043279923.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043272085.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6783310;Reactome: R-HSA-983168	"Protein ubiquitination";"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043278397.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043275147.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_043267196.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043278913.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268308.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043286281.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_043272146.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043283288.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043278571.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043277252.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_043282701.1	5	MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine metabolism"
XP_043273237.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043279133.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_043280187.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815	"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D"
XP_043266805.1	7	Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-8943724	"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription"
XP_043274620.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043266431.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043288751.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135	"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual incision in TC-NER"
XP_043282311.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471	"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"LDL remodeling";"VLDL clearance";"Chylomicron clearance";"VLDL assembly";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron assembly";"Scavenging by Class A Receptors";"LDL clearance";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors"
XP_043278056.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_043275408.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043274508.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043285430.1	42	Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-201722	"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Meiotic recombination";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"DNA methylation";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"Processing of DNA double-strand break ends";"HCMV Late Events";"PRC2 methylates histones and DNA";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Formation of the beta-catenin:TCF transactivating complex"
XP_043273776.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043275182.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043281066.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043274554.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043269799.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043272537.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_043268909.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_043276547.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_043284364.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043284346.1	57	Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5632684	"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state"
XP_043283460.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273007.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043275381.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_043275197.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_043273467.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043280694.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043283044.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043270426.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_043288188.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273677.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043272111.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043283891.1	22	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-5353;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_043276774.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043282449.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043276254.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043278748.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043273928.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043273488.1	9	Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110329;Reactome: R-HSA-5649702;Reactome: R-HSA-9656255;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding";"Cleavage of the damaged purine"
XP_043266715.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043278814.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043280968.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_043284168.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043284003.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043272654.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043289959.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043275733.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_043272242.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_043274981.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes"
XP_043273636.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043274962.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043274920.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043269001.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Synthesis of PA";"Plasmalogen degradation"
XP_043273712.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_043286399.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043289061.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043269547.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043268795.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules"
XP_043278058.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-450520;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins"
XP_043276504.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_043273124.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
XP_043272615.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_043272776.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_043288226.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043286614.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043266619.1	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
XP_043274973.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043286077.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043267803.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_043275136.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_043289465.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043279599.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043282307.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-202424	"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling"
XP_043276954.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043273688.1	5	KEGG: 00270+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00680+1.1.1.95	"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_043281851.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043271787.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043268152.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043271897.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_043288753.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135	"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Dual incision in TC-NER"
XP_043283907.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043267519.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043280965.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_043272448.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_043285900.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_043274455.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043276539.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_043274306.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_043285624.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_043288786.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043276706.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043278561.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043285709.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043280897.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_043280480.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_043272613.1	4	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation"
XP_043285339.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043269340.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043269317.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_043274097.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_043267236.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_043282632.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111458;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109	"Regulation of the apoptosome activity";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_043284094.1	14	KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Synthesis of PC";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism"
XP_043287461.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236	"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043288936.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043278133.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_043287760.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043271278.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_043273867.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_043287007.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_043271435.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_043272544.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043288732.1	13	KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Thermogenesis";"Relaxin signaling pathway"
XP_043272902.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events"
XP_043273647.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348	"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex"
XP_043269795.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043288187.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283900.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043284898.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043288944.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043278742.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043271789.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043285109.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_043274294.1	12	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-5655302;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle";"Signaling by FGFR1 in disease";"mTOR signaling pathway"
XP_043280710.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043280144.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits"
XP_043282041.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043269574.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043286711.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043282725.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7007	"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)"
XP_043270226.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043270856.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043288375.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_043268157.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043281436.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043278372.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043280946.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation"
XP_043282724.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7007	"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)"
XP_043281071.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043282683.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_043285888.1	6	Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368	"Rho GTPase cycle";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation"
XP_043286815.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043280936.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_043273125.1	5	MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_043287393.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_043280597.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-168325	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis"
XP_043272872.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043278933.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_043271831.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_043272336.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043270762.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_043271874.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_043278168.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_043284097.1	14	MetaCyc: PWY-6453;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053	"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II"
XP_043285102.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_043286513.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_043271045.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043290186.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_043282588.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_043274874.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_043273384.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043272467.1	42	MetaCyc: PWY-7779;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7778;MetaCyc: PWY-6863;MetaCyc: PWY-7654;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5789;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-7094;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7726;MetaCyc: PWY-6945;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6946;MetaCyc: PWY-6435	"Methyl tert-butyl ether degradation";"Geraniol degradation";"Toluene degradation";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"2-methylpropene degradation";"Pyruvate fermentation to hexanol (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Propanoate metabolism";"Fermentation to 2-methylbutanoate";"Butanoate metabolism";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Lysine degradation";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoate degradation";"Fatty acid elongation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid salvage";"Carbon fixation pathways in prokaryotes";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Tryptophan metabolism";"Limonene and pinene degradation";"Phenylalanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"beta-Alanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Valine, leucine and isoleucine degradation";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"4-hydroxybenzoate biosynthesis III (plants)"
XP_043280562.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043290143.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718	"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes"
XP_043275065.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043266761.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043272356.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221	"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis"
XP_043268411.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043277250.1	10	Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"RSK activation";"Recycling pathway of L1";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043281809.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043278920.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043268729.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_043269769.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_043287180.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043279578.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043277019.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043287582.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043270579.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043285666.1	29	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-6796648	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_043273873.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_043273432.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043268188.1	7	MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351	"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_043277560.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_043288338.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283624.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043281191.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043282442.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043275981.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_043273440.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043269759.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043268382.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043287951.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_043271366.1	9	MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Nitrogen metabolism"
XP_043283504.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043286020.1	7	KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11	"Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism"
XP_043283613.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_043277205.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation"
XP_043279186.1	6	MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5789	"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_043280953.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-6799198	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis"
XP_043268302.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_043283581.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043271015.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_043280354.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_043287176.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_043266788.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_043271085.1	20	Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69091	"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching"
XP_043267267.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043277602.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_043285187.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043282209.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043277199.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043266744.1	8	KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043276247.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751	"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity"
XP_043279663.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043286894.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043283135.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043279752.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043280748.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_043279564.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043277572.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_043284301.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043276707.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043277038.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043275211.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_043268710.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043282182.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043269976.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_043288527.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_043267973.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043272885.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins"
XP_043277991.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043282325.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_043287189.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043281141.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043283423.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268956.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043271100.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043272360.1	8	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_043275734.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_043269564.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043287298.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_043272624.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043281964.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043270117.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_043276253.1	12	Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-381033;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;KEGG: 00860+4.2.1.24	"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Heme biosynthesis";"Neutrophil degranulation";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"Porphyrin and chlorophyll metabolism"
XP_043274379.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695	"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation"
XP_043272682.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_043284178.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_043281595.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043278482.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_043288408.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043280339.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_043284652.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043279611.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_043269770.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_043274293.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-936440	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling"
XP_043276521.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043276603.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_043275278.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_043271430.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043289798.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043277620.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_043273883.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043275145.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_043278749.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043284913.1	13	MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7220	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_043285240.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_043282974.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"Zeatin biosynthesis"
XP_043267835.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_043288446.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_043272185.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_043274131.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane"
XP_043278152.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043272471.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_043270864.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043275721.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043278841.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043289979.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_043288444.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_043274447.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_043280336.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_043277207.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate cycle"
XP_043271294.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043282436.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880	"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases"
XP_043270518.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043287583.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043273374.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043272996.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_043277893.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_043284116.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11	"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism"
XP_043272601.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_043280590.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5578749	"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs"
XP_043280352.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_043272581.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275774.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043277850.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
XP_043286964.1	8	MetaCyc: PWY-5740;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47	"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043285921.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_043285365.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043285824.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway"
XP_043281979.1	3	Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459	"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_043277945.1	6	Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941	"Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Sucrose biosynthesis II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II"
XP_043270981.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043273489.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043272352.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043278747.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043273225.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043284163.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043269618.1	4	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16	"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_043287126.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043287140.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043267009.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_043271386.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043287530.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043272667.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_043272379.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_043274979.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"MHC class II antigen presentation"
XP_043280272.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_043274618.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043289213.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043275128.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043289112.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043271760.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_043269688.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043279568.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043285911.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_043288221.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043271673.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043271436.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_043274969.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043280952.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-166058	"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_043268948.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_043281587.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043272144.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043286960.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_043288138.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043270775.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
XP_043272901.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_043287985.1	5	Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883	"Neutrophil degranulation";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG"
XP_043281129.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_043272824.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043270861.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268645.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_043282489.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043277742.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043275085.1	15	Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402	"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex"
XP_043283804.1	7	KEGG: 00220+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-6922;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;Reactome: R-HSA-70635	"Arginine biosynthesis";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Arginine and proline metabolism";"Canavanine degradation";"Urea cycle"
XP_043278556.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043268994.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_043275031.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_043269615.1	4	Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16	"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_043289413.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159	"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling"
XP_043272871.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043279666.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_043274095.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043278687.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_043279990.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043282911.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043266377.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_043272458.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043268495.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043282075.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043282177.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043285238.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_043278815.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043288937.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043287123.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043267887.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_043266901.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043280697.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_043287250.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_043285852.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_043268151.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043278867.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_043274546.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_043271318.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_043274207.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_043289167.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_043277862.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043279838.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043289081.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_043283347.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043272998.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_043289791.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043281068.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043278942.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043281636.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043269787.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_043274082.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043272268.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_043280593.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043274514.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_043280214.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway"
XP_043269823.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5632684	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state"
XP_043288870.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283459.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043283401.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_043266510.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043289525.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043284669.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_043275288.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043280873.1	5	Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-205043;Reactome: R-HSA-5205685	"NF-kB is activated and signals survival";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy"
XP_043285337.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043289352.1	26	Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-1368082;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568	"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RORA activates gene expression";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase"
XP_043277549.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_043280038.1	11	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"p38MAPK events";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_043279707.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043271595.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_043287282.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043272616.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_043270010.1	9	Reactome: R-HSA-6782315;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"tRNA modification in the nucleus and cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_043289957.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes"
XP_043273957.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_043270524.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043272841.1	52	Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73863;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-167243;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-6782210	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"mRNA Capping";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_043280335.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_043286242.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_043271433.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_043276361.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_043277195.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043280434.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043278842.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043274331.1	14	MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_043281831.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043287977.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043287651.1	18	Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839	"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE"
XP_043270790.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_043284187.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_043267016.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_043280738.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_043273231.1	4	Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607761	"NIK-->noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_043277257.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043282317.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043290174.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043287482.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_043273646.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-432142	"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL"
XP_043283343.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043283455.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284818.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_043283346.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043272516.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043287905.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043272284.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043269151.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043285412.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-191859;Reactome: R-HSA-400206;Reactome: R-HSA-381340	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation"
XP_043281202.1	4	KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241	"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Peroxisomal protein import"
XP_043286668.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043279518.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300	"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors"
XP_043279665.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_043280740.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043281978.1	3	Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206	"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha"
XP_043285543.1	9	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol"
XP_043289389.1	31	Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-5147;MetaCyc: PWYG-321;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-8012;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-5989;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-6799;MetaCyc: PWY-8049;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-6113	"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"";"Bacterial bioluminescence";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis"
XP_043279447.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043275983.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_043272592.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043277092.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043281228.1	13	Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-975163	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_043287742.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043284113.1	10	KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;Reactome: R-HSA-70171	"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis"
XP_043284605.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043269741.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043274488.1	3	KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
XP_043271128.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043271044.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043281135.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043287746.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043282464.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043267775.1	4	MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7849	"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin III"
XP_043279650.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043274693.1	33	Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-73772;Reactome: R-HSA-75953	"mRNA Capping";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_043274928.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_043274079.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043285882.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043278850.1	1	Reactome: R-HSA-446199	"Synthesis of Dolichyl-phosphate"
XP_043271956.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043286423.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043272772.1	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565	"ESR-mediated signaling";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043273793.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_043279566.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275155.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_043269052.1	1	Reactome: R-HSA-446193	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_043275689.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_043273378.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043272341.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043273723.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_043280624.1	3	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984	"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_043276819.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_043267852.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043271074.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043275922.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043273046.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043282804.1	8	MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_043266794.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_043290138.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043277643.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_043277082.1	8	MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_043283340.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043279717.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043284654.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_043278746.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043268979.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043280821.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043288433.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_043280043.1	11	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043288672.1	11	Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"Mitochondrial protein import"
XP_043274826.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_043287652.1	18	Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051	"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Plasmalogen degradation";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I"
XP_043276121.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_043269548.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043285024.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043275478.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043289508.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_043280982.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_043279555.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043277173.1	4	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation"
XP_043282944.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043275481.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_043281422.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_043283879.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock"
XP_043272757.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_043287605.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_043271672.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043284246.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043289361.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043288349.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043273486.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_043284257.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_043280945.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-1660662	"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism"
XP_043277375.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_043282160.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043287718.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)"
XP_043282721.1	6	MetaCyc: PWY-6908;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-6898	"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III"
XP_043267886.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043267881.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_043268978.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043277642.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_043274953.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_043290142.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043269577.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043282170.1	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_043272656.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802952	"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions"
XP_043284875.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_043267226.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import"
XP_043275993.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
XP_043270828.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043285892.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_043276172.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043269563.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043276192.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043269191.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_043269438.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_043267554.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043280576.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043268797.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066	"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_043282056.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043275673.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72165	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_043275813.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-349425	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_043289631.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_043267574.1	5	KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_043268061.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043276548.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043283629.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228	"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix"
XP_043288337.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043285030.1	42	Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-110329	"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"HCMV Late Events";"PRC2 methylates histones and DNA";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"DNA methylation";"Packaging Of Telomere Ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine"
XP_043281869.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_043278682.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144	"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_043277989.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043272882.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_043271750.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_043273631.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_043281418.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043271038.1	6	Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events"
XP_043272328.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043289842.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_043279793.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043289815.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_043272604.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043286811.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_043288038.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043266501.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043285903.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_043282044.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043288632.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043275819.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-6811440;Reactome: R-HSA-5620916;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Retrograde transport at the Trans-Golgi-Network";"VxPx cargo-targeting to cilium";"COPI-mediated anterograde transport"
XP_043285311.1	3	Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_043267266.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043290181.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_043288355.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_043277646.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_043273644.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-432142	"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL"
XP_043282509.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_043286171.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_043283687.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-376172	"mTOR signaling pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions"
XP_043282761.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043277234.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_043280479.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_043281880.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_043280584.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5668541	"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway"
XP_043278389.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043273474.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_043274917.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043284766.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043267495.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_043272327.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043276243.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043277551.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_043278805.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043268564.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_043274399.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043272391.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043283903.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043284972.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_043272645.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_043271082.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043289903.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_043282609.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133	"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1"
XP_043279928.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
XP_043286493.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043283614.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_043281374.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043280213.1	8	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043285176.1	5	Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2	"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis"
XP_043277683.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043266736.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_043267904.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_043279436.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_043275082.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043271747.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_043281540.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-3214858	"PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines"
XP_043273572.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_043269532.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043275920.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_043278348.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043278869.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_043279586.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043270213.1	8	Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Activation of RAC1";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_043278751.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043267137.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043267811.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043287287.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043283433.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_043279693.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043280387.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043272367.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_043266781.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery"
XP_043285609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043267531.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043287433.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_043270612.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043280316.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_043269882.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-191859	"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly"
XP_043272899.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_043272526.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043279956.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_043287662.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043271359.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043269360.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Cilium Assembly";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors"
XP_043284183.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_043269336.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043284452.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043276638.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043285083.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_043281420.1	16	Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-1660499;Reactome: R-HSA-9009391;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-912526;Reactome: R-HSA-2219530;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-194840	"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Synthesis of PIPs at the plasma membrane";"Extra-nuclear estrogen signaling";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Interleukin receptor SHC signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"Rho GTPase cycle"
XP_043269900.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043271439.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043276944.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043287114.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_043288436.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_043288480.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_043274442.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043282631.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043287010.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043280983.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_043276656.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5610783	"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome"
XP_043272689.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression"
XP_043281808.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043285979.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043277237.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043271919.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_043289366.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043273031.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_043285275.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408	"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation"
XP_043282062.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043273885.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043272887.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion"
XP_043271401.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434	"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Cilium Assembly";"Aggrephagy";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043278727.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_043283833.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_043280255.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_043286783.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_043269530.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043277539.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043275982.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_043269010.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043289297.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_043278131.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043275998.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043288224.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043289484.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes"
XP_043275744.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_043270019.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043285100.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043275181.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043287463.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043283476.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043274976.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_043275332.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression"
XP_043286084.1	17	Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-174417	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis"
XP_043288774.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043269316.1	8	Reactome: R-HSA-6791055;Reactome: R-HSA-163754;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505	"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_043286039.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043271920.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920	"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability"
XP_043280588.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_043276156.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_043274810.1	7	Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-983168	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043269529.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043276480.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043272432.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043280827.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043271142.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_043286436.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043274046.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_043273872.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_043282181.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043275837.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_043275786.1	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;MetaCyc: PWY-4702;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_043287986.1	5	Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695	"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation"
XP_043268259.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043281855.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Gap junction assembly";"Aggrephagy";"Recycling pathway of L1";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors"
XP_043277178.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043289777.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043274563.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043287697.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043267275.1	18	Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_043271340.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_043274459.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_043275059.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_043280839.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_043268677.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_043272145.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043273608.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043288347.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043280161.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_043283287.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043267621.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_043270818.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043267908.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_043277619.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_043276174.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043272876.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_043275635.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043268381.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043287362.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043274927.1	9	Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695	"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Neutrophil degranulation"
XP_043273705.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_043280564.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043281440.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_043273830.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_043287785.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043286683.1	7	Reactome: R-HSA-110362;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-5696400	"POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER"
XP_043287247.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_043278555.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression"
XP_043276834.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_043284169.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_043278493.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043271519.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043270722.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043281454.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043267424.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043280888.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043276741.1	13	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-2214320;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Laminin interactions";"NCAM1 interactions";"Extracellular matrix organization";"ECM proteoglycans";"Anchoring fibril formation";"Signaling by PDGF";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions"
XP_043283448.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_043266413.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_043274431.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_043280483.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043279529.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043274714.1	6	KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_043275653.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_043270385.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043286448.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043274677.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_043288638.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043278794.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043270260.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043278911.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043272184.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043273866.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_043281658.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043274244.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_043275143.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043269537.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043279253.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_043286170.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_043279085.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043284151.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_043270827.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_043267104.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_043284283.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043277441.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043276833.1	8	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_043288731.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_043267533.1	10	MetaCyc: PWY-7661;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83;Reactome: R-HSA-913709;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719360	"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_043267623.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_043280678.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043267386.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-179409	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A"
XP_043273734.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_043278151.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043279025.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043288418.1	4	Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043290170.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043267204.1	8	Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Photosynthesis";"Ion channel transport"
XP_043285331.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_043270261.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043281013.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-112043	"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"DAG and IP3 signaling";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"PLC beta mediated events"
XP_043269979.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_043287404.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043280349.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043280581.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_043266480.1	5	Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_043269313.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043279582.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043271748.1	11	MetaCyc: PWY-6538;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4	"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism"
XP_043279024.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043281063.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043273923.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043282262.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_043278606.1	9	Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043277158.1	17	Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606	"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_043288047.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_043273393.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043288773.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043269605.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278604.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043277397.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043269817.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043272403.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_043281437.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_043288466.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_043273886.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043275135.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_043284866.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_043280695.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043276484.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043268666.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043281925.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043278159.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043290033.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043280680.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_043280333.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043278153.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043282809.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_043269599.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043278319.1	6	KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;MetaCyc: PWY-7346	"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_043284576.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_043270911.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_043289843.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_043281069.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043279432.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5678895	"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis"
XP_043269192.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043288985.1	6	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"One carbon pool by folate"
XP_043270820.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_043270246.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043277108.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_043281016.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5607763	"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Regulation of insulin secretion";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_043275052.1	12	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_043288778.1	7	KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2	"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism"
XP_043266407.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_043279348.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_043277167.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043289556.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043289263.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_043281585.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043268641.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043277821.1	10	MetaCyc: PWY-6317;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2	"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043274809.1	7	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)"
XP_043275030.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_043268189.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_043281542.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043275969.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
XP_043273449.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_043275968.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975	"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA"
XP_043269836.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_043281507.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043278750.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043274380.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291	"HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C"
XP_043282928.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_043289595.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043268345.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043270575.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043267144.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_043278456.1	12	MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-6683;Reactome: R-HSA-174362	"Sulfate activation for sulfonation";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Monobactam biosynthesis";"Purine metabolism";"Sulfite oxidation III";"Purine metabolism";"Sulfur metabolism";"Selenate reduction";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS"
XP_043275919.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_043272904.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043277482.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_043289499.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_043270717.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_043277362.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043277026.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043276644.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043280794.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043288976.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043286893.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043285935.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043287656.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043274084.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043288036.1	31	MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-5147;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-8012;MetaCyc: PWYG-321;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-6799;MetaCyc: PWY-5966-1;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-5366;Reactome: R-HSA-9029558;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-6113;Reactome: R-HSA-163765	"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitoleate biosynthesis II (plants and bacteria)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression"
XP_043270603.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043283727.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043287283.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043275134.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_043276332.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043278021.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_043284372.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043267010.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_043268079.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043284165.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043271523.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043272266.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_043276349.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism"
XP_043271716.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043273733.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_043276765.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_043288310.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043267240.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_043289807.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043284562.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043280732.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_043276973.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_043280703.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043268765.1	16	MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-7124;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-5723	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt"
XP_043273542.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_043279427.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_043289077.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-380320	"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Kinesins";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes"
XP_043272509.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043285457.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952	"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions"
XP_043282664.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043287407.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043270567.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_043270013.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_043285923.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043276264.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043280696.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_043279207.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043274822.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_043275622.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043288912.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043279722.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043287397.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043266859.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043288892.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043280800.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043285651.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_043284171.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043286509.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_043280295.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_043278716.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043289862.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_043280455.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043275773.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043267255.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043279855.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043282067.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043276536.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_043286483.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043279921.1	10	MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-6613	"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_043281543.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha"
XP_043270884.1	14	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-1632852	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Macroautophagy"
XP_043270757.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043281829.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043273616.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_043289036.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_043282308.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043278484.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043274850.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165	"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth"
XP_043284270.1	5	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-446388;Reactome: R-HSA-194840;Reactome: R-HSA-8964616	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"Rho GTPase cycle";"G beta:gamma signalling through CDC42"
XP_043269569.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043284905.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043284638.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_043267465.1	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_043286467.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_043273003.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043285021.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764	"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling"
XP_043269992.1	9	Reactome: R-HSA-6782315;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"tRNA modification in the nucleus and cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043283904.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043280494.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043280730.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_043269910.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_043269576.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043274453.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043270662.1	10	Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764	"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling"
XP_043286445.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043287599.1	9	MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"PLC beta mediated events"
XP_043269572.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043279718.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043285017.1	42	Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-2299718;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-3214847	"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Meiotic synapsis";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"PRC2 methylates histones and DNA";"HCMV Late Events";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Condensation of Prophase Chromosomes";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"HATs acetylate histones"
XP_043280254.1	19	KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00710+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-6728;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37	"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation in photosynthetic organisms";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism"
XP_043280892.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043275452.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-1222556	"Photosynthesis";"Ion channel transport";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ATP biosynthesis";"ROS and RNS production in phagocytes"
XP_043286609.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043272272.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_043277072.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043280812.1	7	Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8	"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043268383.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043279587.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284170.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_043283068.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_043272447.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_043284341.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_043279292.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043270262.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043269347.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_043286411.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043283365.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043284965.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_043269323.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_043283701.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043270011.1	24	Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Aggrephagy";"Cilium Assembly";"Gap junction assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Kinesins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043274071.1	3	Reactome: R-HSA-189085;Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043275523.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043278447.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043286035.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_043289261.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_043279715.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043288159.1	13	Reactome: R-HSA-74259;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7821;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187	"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_043271902.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-389357	"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling"
XP_043269652.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_043272407.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043283575.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043286648.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043286963.1	8	MetaCyc: PWY-5740;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47	"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_043266528.1	14	MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-418217;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-500657;KEGG: 00562+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"G beta:gamma signalling through PLC beta";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Presynaptic function of Kainate receptors";"Inositol phosphate metabolism";"Ca2+ pathway";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"PLC beta mediated events"
XP_043279288.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043271815.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_043275834.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_043272462.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043287741.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043267866.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043281708.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_043268520.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_043284044.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_043270080.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_043283700.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043269696.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043285897.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043271640.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043280837.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_043276996.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043280618.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_043286298.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043277078.1	4	Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10	"Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043281956.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_043272419.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_043276492.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043279922.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043268315.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_043280229.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_043283875.1	11	MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7456	"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Beta-(1,4)-mannan degradation"
XP_043279765.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043280328.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043282081.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043284924.1	3	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_043266628.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043270151.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_043279946.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_043278929.1	10	KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6369;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158	"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism"
XP_043286650.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043272986.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043267458.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043274574.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_043286895.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits"
XP_043276778.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178	"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans"
XP_043270857.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
XP_043282709.1	5	KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)"
XP_043268679.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043288660.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043276482.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043273941.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_043269892.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation"
XP_043277851.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043287716.1	13	KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_043275225.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_043274798.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043269837.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043284241.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043274081.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043283009.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_043268058.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_043266939.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_043286073.1	19	Reactome: R-HSA-8950505;Reactome: R-HSA-4420097;Reactome: R-HSA-428543;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-5663220;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-114604	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"VEGFA-VEGFR2 Pathway";"Inactivation of CDC42 and RAC1";"Myogenesis";"EGFR downregulation";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate Formins";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade"
XP_043288398.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043286459.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_043279161.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_043271682.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_043275235.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_043280162.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_043274675.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043274467.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043273607.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043272586.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121	"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI"
XP_043280668.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043283902.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043271319.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_043284184.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_043287369.1	8	Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Photosynthesis";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_043279837.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043268320.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_043270814.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_043281116.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_043280218.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_043280840.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_043267014.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_043287035.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_043279948.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043288048.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_043284240.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043288716.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_043279486.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043268149.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043281024.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis"
XP_043270517.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043284243.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043267299.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043281439.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_043267975.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043275562.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-2173789	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"UCH proteinases";"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs"
XP_043277696.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_043274581.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043285013.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043268250.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043285366.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043266500.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043276945.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_043273789.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_043280276.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_043288553.1	11	Reactome: R-HSA-909733;Reactome: R-HSA-391160;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-210990;Reactome: R-HSA-389948;Reactome: R-HSA-912694;Reactome: R-HSA-9008059	"Interferon alpha/beta signaling";"Signal regulatory protein family interactions";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"PECAM1 interactions";"PD-1 signaling";"Regulation of IFNA signaling";"Interleukin-37 signaling"
XP_043279616.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043282216.1	18	Reactome: R-HSA-1483166;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4	"Synthesis of PA";"Plasmalogen degradation";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_043281428.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_043281137.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043267368.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_043290182.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_043287581.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043281218.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043268812.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_043288631.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_043286947.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_043268206.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_043271540.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408	"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Separation of Sister Chromatids";"ISG15 antiviral mechanism"
XP_043281019.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-422356	"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Ca2+ pathway";"Regulation of insulin secretion"
XP_043274768.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043277515.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043277994.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043271528.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_043269713.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043283999.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_043274460.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_043288928.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043281220.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043269732.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_043268422.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism"
XP_043276544.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_043277848.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043276055.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268	"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_043287535.1	13	KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Hyaluronan uptake and degradation"
XP_043280823.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043283620.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_043274434.1	4	KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603	"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine"
XP_043274402.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043280044.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_043278551.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression"
XP_043280976.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_043266829.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_043280933.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043271735.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_043276263.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043286446.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043274304.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_043276363.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_043289362.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043266743.1	8	KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Fructose and mannose metabolism";"Starch and sucrose metabolism"
XP_043278641.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043274040.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043266776.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043287906.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043278239.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043286240.1	13	Reactome: R-HSA-9027277;Reactome: R-HSA-2871809;Reactome: R-HSA-202433;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-2424491;Reactome: R-HSA-2029485;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796	"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"DAP12 signaling";"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"FCERI mediated MAPK activation"
XP_043266699.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_043267207.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043289166.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_043274712.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043272345.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043285127.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_043277831.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043282968.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043269800.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043288562.1	11	Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-877312;Reactome: R-HSA-114604;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-389948;Reactome: R-HSA-210990	"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"Regulation of IFNG signaling";"GPVI-mediated activation cascade";"Regulation of IFNA signaling";"Interleukin-37 signaling";"PD-1 signaling";"PECAM1 interactions"
XP_043273641.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-432142	"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"RAF activation";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL"
XP_043271068.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043283579.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043289325.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_043273671.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043288634.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043281576.1	3	Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320	"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH"
XP_043277997.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_043280453.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043277080.1	5	KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;Reactome: R-HSA-432720	"Glycosaminoglycan degradation";"Neutrophil degranulation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis"
XP_043280355.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043281830.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043275206.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043270231.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_043280237.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043285426.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043266899.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_043276863.1	7	MetaCyc: PWY-6134;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-7158	"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V"
XP_043281522.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043276989.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_043273979.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043272347.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043282185.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043269250.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_043270069.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_043285944.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287	"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery"
XP_043287692.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043278144.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_043272582.1	52	Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-167161;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167162	"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape"
XP_043282636.1	5	Reactome: R-HSA-111458;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069	"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity"
XP_043278935.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_043276348.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782	"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis"
XP_043282357.1	12	KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-6672;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5133	"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis"
XP_043276347.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051	"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis I"
XP_043282356.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_043281046.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043269684.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_043273422.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_043269190.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043269536.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043269578.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043278477.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_043272183.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-912446	"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination"
XP_043287715.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-1660662	"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism"
XP_043274711.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043284579.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_043282649.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_043288317.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching"
XP_043270711.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043270863.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346	"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis"
XP_043276955.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043272191.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987	"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2"
XP_043283618.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_043270406.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate"
XP_043268762.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043271947.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043273942.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_043280571.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043289252.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_043278609.1	9	Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043273737.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_043276869.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043285368.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043288977.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043274427.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043286437.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_043281524.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043277699.1	3	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_043283773.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043268144.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043278552.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206	"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha"
XP_043276968.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_043283069.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_043277200.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043277071.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043282048.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043280698.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_043286421.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043278232.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_043284763.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043269978.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001	"PIP3 activates AKT signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade"
XP_043278197.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_043272900.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_043284188.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043277166.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043281825.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_043288940.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043284018.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043285359.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043284561.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043270881.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_043278337.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043283799.1	13	MetaCyc: PWY-561;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2	"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)"
XP_043269982.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-109704	"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"PI3K Cascade"
XP_043276630.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043282765.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043287472.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1	"Neutrophil degranulation";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation II"
XP_043282774.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_043274284.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233	"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway"
XP_043275723.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043284662.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_043283008.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_043289046.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043277235.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043285886.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_043270798.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043268365.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_043270216.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043284338.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043267002.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_043283254.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_043280739.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_043274748.1	13	KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7222;Reactome: R-HSA-499943	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates"
XP_043275263.1	1	Reactome: R-HSA-156590	"Glutathione conjugation"
XP_043289603.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043270822.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_043287277.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043275838.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors"
XP_043289664.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043277951.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043290184.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_043272833.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043285132.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_043268370.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043284112.1	10	KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11	"Pentose phosphate pathway";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism"
XP_043289776.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_043290099.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_043269818.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043289769.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_043279044.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_043277175.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_043270079.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_043275180.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043288476.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_043267242.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_043285435.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_043272585.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043277544.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_043281441.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_043281108.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043267521.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043269201.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043277083.1	8	MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_043279924.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043280332.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043280575.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043284802.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_043271590.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043274755.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_043268553.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043280460.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"Kinesins";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Cilium Assembly";"Gap junction assembly";"Aggrephagy"
XP_043276108.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_043268482.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043269906.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_043288837.1	12	MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051	"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I"
XP_043286079.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043274616.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043288122.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154	"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Neutrophil degranulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Neddylation";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin"
XP_043273436.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043266759.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043279113.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Plasmalogen degradation";"Ether lipid metabolism"
XP_043287616.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043272310.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043280389.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043273126.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_043286689.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043282064.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043266895.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_043270833.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043268179.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5873	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_043267520.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043288803.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043269596.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043272475.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_043272459.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043273021.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043269127.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043272269.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_043280635.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-349425	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_043286218.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043286791.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_043268631.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043267412.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043285431.1	42	Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-5250924;Reactome: R-HSA-8939236;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-2299718;Reactome: R-HSA-73728	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"DNA methylation";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening"
XP_043283702.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043283868.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_043277273.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_043283876.1	11	MetaCyc: PWY-5659;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8	"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_043288339.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043267909.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_043278667.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695	"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation"
XP_043287224.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway"
XP_043286395.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_043284734.1	13	KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_043272941.1	13	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946	"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants"
XP_043275178.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043285704.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_043282595.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043283722.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_043290167.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_043268562.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_043283121.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043281274.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043283124.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043281227.1	13	Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460	"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway"
XP_043289645.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043269521.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_043278923.1	4	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_043268720.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043283035.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_043274057.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_043275807.1	14	KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-6969;Reactome: R-HSA-71403	"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)"
XP_043282665.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043285674.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_043281868.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_043289129.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_043286508.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_043277547.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_043266844.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation"
XP_043285488.1	4	KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558	"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine"
XP_043280032.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043286799.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_043283357.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043271288.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043287892.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043282766.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043270926.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043272162.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_043285544.1	9	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol"
XP_043276561.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237	"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2"
XP_043267373.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043283056.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043276969.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_043268262.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-2894862;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-75893;Reactome: R-HSA-1251985	"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Growth hormone receptor signaling";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"TNF signaling";"Nuclear signaling by ERBB4"
XP_043285896.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043280216.1	8	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043271812.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_043270485.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043278581.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043282445.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043273291.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_043269491.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043282061.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043282321.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_043278420.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_043276846.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_043267070.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043268863.1	14	KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417	"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_043272834.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043276551.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_043269801.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043278022.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_043266896.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation"
XP_043272884.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_043278584.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043278490.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043281120.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_043281805.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043278637.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043286842.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043272298.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043270015.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes"
XP_043268761.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043282095.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043284507.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250	"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_043273455.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043271423.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043271290.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-193692	"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR"
XP_043281117.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_043279774.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043270663.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590	"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling"
XP_043281458.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043277872.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_043290139.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_043267027.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_043283752.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_043268264.1	12	Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-75893;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-982772;Reactome: R-HSA-5362798	"Collagen degradation";"Signaling by EGFR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"TNF signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell"
XP_043281168.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043285480.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_043283458.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043282820.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043286188.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043277081.1	8	MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7187;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates"
XP_043281616.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043280853.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_043274072.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_043289011.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_043269730.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
XP_043269792.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043287790.1	3	KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_043278719.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043280390.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043273921.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043289789.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043281419.1	16	Reactome: R-HSA-194840;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-912631	"Rho GTPase cycle";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL"
XP_043280221.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043278961.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_043287405.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043272588.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7717	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_043268350.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043279189.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043267399.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043281435.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043288290.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043274134.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-389513	"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"RAF activation";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling"
XP_043272843.1	52	Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-73776;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-73980	"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination"
XP_043282293.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_043287360.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_043290065.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_043281060.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043272207.1	5	KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556	"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes"
XP_043272164.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_043275736.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043280391.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043286845.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043276275.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043280353.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_043267978.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_043279973.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043273782.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_043271402.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"Kinesins";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Cilium Assembly";"Gap junction assembly";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs"
XP_043274301.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043283663.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_043272137.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043277987.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043270610.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043269031.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_043287037.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_043275589.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism"
XP_043273430.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043277701.1	7	KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;MetaCyc: PWY-6470;Reactome: R-HSA-446193;Reactome: R-HSA-4549356;MetaCyc: PWY-5265	"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis II (staphylococci)"
XP_043271140.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_043270937.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811434	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043273487.1	18	MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_043283155.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043282557.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_043286457.1	11	KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6964;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381	"Arginine biosynthesis";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)"
XP_043274522.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043272342.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043287468.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043280407.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_043274029.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis"
XP_043278340.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_043266770.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043284137.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
XP_043280183.1	57	Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408	"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Neutrophil degranulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_043278580.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043269909.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
XP_043271075.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043267257.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043286512.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_043274167.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043279124.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_043285513.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_043273865.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_043280566.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043287737.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043272994.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043273162.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection"
XP_043282345.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_043287253.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-168325	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis"
XP_043287231.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167243	"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery"
XP_043285898.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043278813.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043273229.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043284580.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_043268910.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043268405.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828	"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis"
XP_043280809.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586	"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_043289813.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion"
XP_043272621.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043274083.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043273008.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_043266580.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043282076.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043285901.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859	"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly"
XP_043272988.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_043276770.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043280482.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043275354.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043281927.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043276545.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_043287400.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043284791.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043285512.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_043273321.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-6142	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_043267428.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043269543.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043274513.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_043271013.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_043269546.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043274679.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_043289758.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043278134.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_043278914.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268034.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_043287030.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_043288264.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043280326.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043280731.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043290020.1	40	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"mRNA Capping";"HIV Transcription Initiation"
XP_043270421.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_043271545.1	33	Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408	"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism"
XP_043274426.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043274069.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043271653.1	52	Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481	"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints"
XP_043269492.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043283869.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_043269731.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043277542.1	5	Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_043274968.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043288980.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043284751.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043281140.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043280536.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_043285188.1	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_043275346.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043286930.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_043280219.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein"
XP_043268062.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043284466.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_043282720.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043284024.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_043274963.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043270149.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043286817.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_043287722.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662	"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism"
XP_043286419.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043282349.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_043274428.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043266641.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043287607.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism"
XP_043281828.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043273509.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043282276.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043269194.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_043273611.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043285631.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5	"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_043275741.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043285978.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043275598.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_043285977.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043275792.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis"
XP_043282508.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043271650.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043288755.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_043276485.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043270907.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043281064.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043275506.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_043274156.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-437239	"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1"
XP_043270021.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746	"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein"
XP_043276571.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043286765.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_043279559.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043275738.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043273173.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HATs acetylate histones";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression"
XP_043272291.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_043288123.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043286877.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043274623.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_043286434.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome"
XP_043273609.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043281604.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_043282824.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043286626.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_043271342.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_043289090.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_043288465.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043279820.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-391160;Reactome: R-HSA-6798695;Reactome: R-HSA-202733	"Integrin cell surface interactions";"Signal regulatory protein family interactions";"Neutrophil degranulation";"Cell surface interactions at the vascular wall"
XP_043270811.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043286616.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043268421.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism"
XP_043271597.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_043266575.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043285031.1	42	Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-5250924;Reactome: R-HSA-8939236;Reactome: R-HSA-110331;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-2299718;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-9609690	"G2/M DNA damage checkpoint";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged purine";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Meiotic recombination";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"Condensation of Prophase Chromosomes";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"HCMV Late Events";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events"
XP_043284344.1	9	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-113501	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching";"DNA replication initiation";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_043275848.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043269048.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043287226.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043287113.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_043281635.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_043283300.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043275409.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043281942.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_043280358.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043275594.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_043282300.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_043274155.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Aggrephagy";"Gap junction assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors"
XP_043269082.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_043280491.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043274802.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_043267755.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_043278132.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_043282731.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_043286837.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043281188.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_043289904.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043288925.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68616	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_043278476.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_043271911.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400	"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_043290106.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_043288663.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043289034.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_043274967.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_043289715.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-3561	"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Choline biosynthesis III"
XP_043278446.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043276604.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_043270078.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_043276709.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043267243.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_043282058.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043275597.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043271808.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043284585.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_043266495.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043284245.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043288979.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043278142.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_043283570.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_043280184.1	57	Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346	"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Hedgehog 'on' state";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis"
XP_043284313.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043266583.1	5	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis"
XP_043270378.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043285860.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_043280580.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043290136.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_043286667.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043289883.1	29	Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-3371453;Reactome: R-HSA-5656121;Reactome: R-HSA-3108214;Reactome: R-HSA-5656169	"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLI";"SUMOylation of DNA damage response and repair proteins";"Termination of translesion DNA synthesis"
XP_043275805.1	14	MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-71403;Reactome: R-HSA-611105;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1	"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)"
XP_043285676.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_043266548.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_043285823.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_043289106.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043281804.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043285696.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043280719.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043281378.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_043287833.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_043274268.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_043285893.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_043278212.1	11	Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604	"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling"
XP_043287966.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_043281920.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_043284569.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043269009.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043268268.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_043278130.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043273651.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043276783.1	7	MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;Reactome: R-HSA-73817;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205	"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Neutrophil degranulation";"Purine metabolism"
XP_043274915.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043266451.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043282444.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043275987.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043268667.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043268270.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-879415	"Asparagine N-linked glycosylation";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling"
XP_043285694.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043270925.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043281192.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043289713.1	7	Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039	"Synthesis of PG";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Choline biosynthesis III";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_043266499.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043284212.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043286080.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043274980.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_043284248.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043286655.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275351.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043269446.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467	"Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs"
XP_043268344.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043276759.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043277269.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_043268303.1	8	Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_043275619.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043271732.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_043288529.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043276793.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043283298.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043288222.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043272999.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_043271048.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043286308.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043271422.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043270423.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_043287367.1	8	Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712	"Insulin receptor recycling";"ATP biosynthesis";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Photosynthesis";"Ion channel transport"
XP_043280996.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_043275398.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_043283775.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_043286890.1	4	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism"
XP_043287654.1	18	KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1483166	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Plasmalogen degradation";"Synthesis of PA"
XP_043276673.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043266870.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043286847.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043266629.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_043276245.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903	"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy"
XP_043271531.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632	"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis"
XP_043271670.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043273452.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043287734.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043272709.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_043268796.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662	"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling"
XP_043278737.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043279777.1	52	Reactome: R-HSA-75953;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-73772;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-167287	"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"HIV Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"FGFR2 alternative splicing";"HIV elongation arrest and recovery"
XP_043273891.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_043274320.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_043280751.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043283615.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_043266531.1	14	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-418217;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-500657;KEGG: 04070+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"G beta:gamma signalling through PLC beta";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Ca2+ pathway";"Inositol phosphate metabolism";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"Phosphatidylinositol signaling system"
XP_043280891.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043274767.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043273454.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043284890.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043282525.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_043281470.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043282648.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_043275348.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043286618.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043281189.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043266709.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091	"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells"
XP_043277373.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_043281811.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043282173.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043266947.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_043274760.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_043272916.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-3232142;Reactome: R-HSA-983168;Reactome: R-HSA-1234176	"Neddylation";"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_043280727.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_043289703.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_043277554.1	10	Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72731	"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP"
XP_043278161.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043289278.1	6	MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00030+5.1.3.1	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_043283975.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_043266741.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_043267801.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043287017.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_043279426.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_043280932.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043280185.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-1169091	"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells"
XP_043281391.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043273451.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043288926.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin"
XP_043282527.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_043266717.1	7	Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826	"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_043271432.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043278864.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_043278861.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043280217.1	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway"
XP_043288500.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_043282379.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043268865.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043275621.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043282204.1	10	KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23	"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Other glycan degradation"
XP_043279767.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043284784.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs"
XP_043282865.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_043278395.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_043279827.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043271524.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_043283380.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043273571.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043272889.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_043274974.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043280909.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043278800.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043267276.1	18	Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167287	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery"
XP_043284604.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043287036.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_043275980.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_043270358.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
XP_043269154.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation"
XP_043290176.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_043270908.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043269208.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043275756.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043289398.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_043273629.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_043282970.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_043270268.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043273194.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508	"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_043286816.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_043281648.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_043273749.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_043272905.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events"
XP_043287703.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043286275.1	4	KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030	"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis"
XP_043277952.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043279835.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043287750.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway"
XP_043277595.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939236	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_043270119.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043271620.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043268864.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043288458.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_043286117.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_043289276.1	5	MetaCyc: PWY-7177;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176	"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis"
XP_043270068.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_043277187.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043268766.1	16	MetaCyc: PWY-7124;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-5484;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-1622;MetaCyc: PWY-2221;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11	"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism"
XP_043288160.1	13	KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;Reactome: R-HSA-74259;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7821	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Tunicamycin biosynthesis"
XP_043284167.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_043284012.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043282510.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_043277323.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_043276352.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051	"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis I"
XP_043282358.1	12	KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132	"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis"
XP_043282855.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_043286733.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043266491.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding"
XP_043266539.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_043284567.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043269739.1	3	Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4	"Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_043286489.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043268763.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_043273327.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043277084.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043275917.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043283041.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043283354.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043276642.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043268681.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043286429.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_043281107.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043268022.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043285825.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1	"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism"
XP_043273880.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_043266719.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_043274943.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_043281760.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_043288688.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_043272623.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_043284642.1	25	Reactome: R-HSA-8951936;Reactome: R-HSA-8949275;Reactome: R-HSA-8939242;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245;Reactome: R-HSA-8939246;Reactome: R-HSA-8934593;Reactome: R-HSA-8931987;Reactome: R-HSA-8941326;Reactome: R-HSA-8951911;Reactome: R-HSA-8939247;Reactome: R-HSA-8941333;Reactome: R-HSA-8939236;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8939256;Reactome: R-HSA-8939243;Reactome: R-HSA-8941858;Reactome: R-HSA-8935964;Reactome: R-HSA-8877330;Reactome: R-HSA-8941332;Reactome: R-HSA-8941284;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222	"RUNX3 regulates p14-ARF";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates bone development";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX3 expression and activity";"RUNX1 regulates expression of components of tight junctions";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates chondrocyte maturation";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis"
XP_043273293.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_043285243.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_043270225.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043287801.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746	"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein"
XP_043283359.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043273961.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_043272174.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987	"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2"
XP_043285382.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043281941.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_043280385.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043282574.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_043277656.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_043266529.1	14	KEGG: 04070+3.1.4.11;Reactome: R-HSA-500657;MetaCyc: PWY-8052;Reactome: R-HSA-434316;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-418217;Reactome: R-HSA-1855204;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"PLC beta mediated events";"Ca2+ pathway";"Inositol phosphate metabolism";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism"
XP_043268355.1	7	MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;Reactome: R-HSA-1660662	"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_043268148.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043268207.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_043279789.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_043274096.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043272389.1	8	KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-71336;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P"
XP_043275109.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043278803.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043286804.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043288144.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_043280516.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043269062.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_043274830.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_043289768.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043282473.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_043280207.1	15	Reactome: R-HSA-1227986;Reactome: R-HSA-9652282;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-9665249;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665233	"Signaling by ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to trastuzumab"
XP_043274318.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043278507.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043288986.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043275748.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043286138.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043273604.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043283952.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043272992.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043271973.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043288471.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043278802.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043288715.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_043282563.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_043272678.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_043289108.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_043273597.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733	"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_043280030.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043274363.1	40	Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-9018519	"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"mRNA Capping";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression"
XP_043288777.1	7	Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921	"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_043272982.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_043275870.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043284078.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_043274549.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-180585	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G"
XP_043275636.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043290145.1	14	Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-1474228;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862	"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043279841.1	4	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism"
XP_043267787.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043286095.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_043268322.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_043274759.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_043283045.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043273453.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043279197.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043272513.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043277079.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2206305	"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D"
XP_043281072.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043288004.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_043283906.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043275194.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043280394.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043285620.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043273610.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043285410.1	4	Reactome: R-HSA-189483;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937	"Heme degradation";"Heme degradation I";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport"
XP_043269686.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043274552.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043279853.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043267573.1	57	Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174113	"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1"
XP_043279187.1	6	MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-4381	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_043267149.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043271795.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043269562.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043271785.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_043267400.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043277468.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_043276450.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043273034.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_043277892.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism"
XP_043285133.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_043283699.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043279762.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043273534.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043283368.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043282892.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_043273043.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_043266942.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_043288640.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043276113.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_043278945.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043285549.1	9	Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323	"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol"
XP_043283352.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043280859.1	19	MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5392	"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II"
XP_043267411.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043286216.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043274970.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043275061.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043287753.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_043272761.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_043273032.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_043269533.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043274231.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_043279438.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_043279993.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043281500.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_043269046.1	19	Reactome: R-HSA-3214858;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-8876725;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"RMTs methylate histone arginines";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Protein methylation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_043283446.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043276700.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043278044.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_043279450.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043276972.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_043288117.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284015.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043288626.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043282472.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_043273948.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_043270035.1	9	Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315	"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol"
XP_043269518.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043286679.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_043282074.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043269262.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043288641.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043281767.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_043267011.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_043274807.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043276248.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191	"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC"
XP_043289559.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043270189.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275086.1	15	Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5467337	"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding"
XP_043270609.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043274865.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043288431.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_043275500.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_043287972.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_043279842.1	4	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism"
XP_043274267.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_043275842.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_043278736.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043273040.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_043269493.1	6	Reactome: R-HSA-446210;MetaCyc: PWY-7077;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25	"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism"
XP_043268709.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043270420.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_043275488.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_043289045.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043269715.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043276988.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_043283647.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_043278524.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043275356.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043279441.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043277644.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_043277467.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_043267619.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_043279596.1	17	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Fanconi Anemia Pathway";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"PI3K-Akt signaling pathway";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Human papillomavirus infection"
XP_043277321.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_043287398.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043266820.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043268147.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043282316.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043289365.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043266842.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-5381;MetaCyc: PWY-7185	"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine metabolism";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I"
XP_043277613.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268946.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation"
XP_043278500.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043268905.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043289385.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043283033.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_043282635.1	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;MetaCyc: PWY-4361;Reactome: R-HSA-9627069	"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity"
XP_043279766.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043285454.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043276266.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043274273.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043289614.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043270000.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043286116.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_043288292.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273605.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043269559.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043271383.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043269195.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_043285984.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_043287395.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043266713.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_043271280.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043271484.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_043280599.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_043269363.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043274820.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_043288462.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043272760.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_043284134.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria"
XP_043277988.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043281424.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_043279991.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043275965.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_043283672.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_043286122.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043289404.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043286486.1	17	KEGG: 04150+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-8953750;Reactome: R-HSA-69473;Reactome: R-HSA-69601;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Transcriptional Regulation by E2F6";"G2/M DNA damage checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection"
XP_043274099.1	26	Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-8866654;Reactome: R-HSA-5656121;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-110320	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by POLI";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"Translesion Synthesis by POLH"
XP_043282057.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043271126.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_043285318.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043282570.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043281652.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043284477.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043271483.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_043272579.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043280384.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043281812.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043280042.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043276141.1	4	MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_043281197.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043286730.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284478.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043277978.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_043272354.1	12	Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-399719	"NrCAM interactions";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors"
XP_043286061.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling"
XP_043279544.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_043268853.1	14	KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634	"Ether lipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport"
XP_043272433.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043288049.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_043287430.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_043281541.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082	"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression"
XP_043277051.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043284865.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_043284063.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_043286358.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_043278486.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043272108.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_043289262.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043286447.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043268954.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043287540.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_043274470.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7328;Reactome: R-HSA-70370;Reactome: R-HSA-5609977	"Galactose metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_043281603.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_043279218.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_043282339.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_043271592.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_043272903.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_043286004.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism"
XP_043287757.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043289560.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043270692.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043283186.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate"
XP_043285386.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_043288794.1	7	KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3	"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_043281090.1	6	Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_043275544.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043281237.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043274548.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2	"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism"
XP_043285322.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_043267851.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043274639.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_043283266.1	29	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-6781823	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex"
XP_043273435.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043280493.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_043285583.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_043267560.1	6	KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)"
XP_043283442.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043281014.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809	"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization"
XP_043283547.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_043281119.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_043283217.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_043266811.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043283351.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043269714.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043277864.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043289050.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_043282150.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043279126.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_043274211.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_043275701.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043276708.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043275672.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043286744.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043281591.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043276923.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043274728.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_043270465.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_043280279.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_043286091.1	5	MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism"
XP_043269534.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043268304.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation"
XP_043287936.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043288756.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110320	"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH"
XP_043272265.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_043283708.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_043286046.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043268155.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043279651.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-165181	"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB"
XP_043277270.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043275596.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043268307.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043277600.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_043266478.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043270222.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_043285795.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043271771.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043283686.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24	"DSCAM interactions";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"mTOR signaling pathway"
XP_043277206.1	9	MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation"
XP_043286800.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043280818.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043280209.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_043286897.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043269153.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043281823.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_043276157.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_043287276.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043270476.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_043283884.1	32	Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-76042	"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_043285889.1	15	Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043269196.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_043280975.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_043279839.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043273057.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043281520.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043273704.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_043283944.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043286476.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_043278510.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_043280661.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043281703.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043288088.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Nitrogen metabolism"
XP_043287948.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_043273790.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043266714.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043268142.1	5	KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_043288639.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_043270723.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284920.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043287683.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043270269.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043282912.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043267114.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_043288445.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_043286774.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_043279056.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043287950.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043285436.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_043287080.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043279299.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043270005.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043271657.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_043281173.1	4	KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16	"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_043288429.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_043285548.1	9	Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_043283126.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043267517.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043281230.1	13	Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-9645460	"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway"
XP_043273947.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_043269768.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_043273029.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_043283341.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043277546.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_043272870.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043267905.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563	"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription"
XP_043283865.1	5	Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21	"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism"
XP_043279196.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043271067.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043282148.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_043267796.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532	"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer"
XP_043278583.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043286141.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043289814.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor"
XP_043278717.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043280615.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_043289464.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043274637.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1"
XP_043267241.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_043274076.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043284574.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043285356.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043277236.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043272494.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_043268830.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_043284570.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043289082.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_043284117.1	4	Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Propanoate metabolism"
XP_043283941.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043288767.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043288748.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043284211.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043272911.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_043282571.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-9610379	"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events"
XP_043282719.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_043282873.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_043284925.1	3	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_043278883.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-381183	"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_043272648.1	5	KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013	"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_043270774.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_043270786.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_043274278.1	7	Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_043285547.1	9	Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_043276195.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043289717.1	7	MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-3561	"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Synthesis of PA";"Choline biosynthesis III"
XP_043280828.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_043282471.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_043268907.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_043275063.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043288851.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284886.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043286540.1	7	KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis"
XP_043274766.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268711.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043286005.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism"
XP_043289844.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_043278807.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275093.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043278566.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043278129.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_043275234.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043270230.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_043275334.1	5	Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427	"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins"
XP_043285128.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_043273206.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912	"MHC class II antigen presentation";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane"
XP_043275715.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043275743.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043272963.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)"
XP_043280619.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_043277626.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_043284085.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043273591.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_043274385.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-382556	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport"
XP_043276158.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi"
XP_043274398.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043281113.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043272671.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-3371571	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"HSF1-dependent transactivation"
XP_043266408.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_043287767.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043269896.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043266894.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_043275566.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_043280210.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_043280457.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043285677.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_043280904.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_043281589.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043272877.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins"
XP_043278603.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043277834.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_043283084.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_043287280.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043285943.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167287	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery"
XP_043268020.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043289399.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_043274875.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_043286892.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043271064.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_043285468.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952	"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions"
XP_043280749.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043281593.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043268934.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Recycling pathway of L1";"Aggrephagy";"Gap junction assembly";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Mitotic Prometaphase"
XP_043287890.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043280570.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043266864.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043277396.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition"
XP_043279421.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism"
XP_043268131.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)"
XP_043278904.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043274335.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043270614.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043282803.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_043286115.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_043267635.1	12	KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-5484	"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)"
XP_043269570.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210	"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_043271679.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_043278738.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043283042.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043286181.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043274119.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_043282248.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_043279526.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043272507.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_043273673.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043288040.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_043267410.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043283477.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_043276971.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_043272330.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043289363.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043283024.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043276939.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_043271419.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043285441.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852	"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Macroautophagy"
XP_043283364.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043287843.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043271546.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-2467813	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Separation of Sister Chromatids"
XP_043275069.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043274226.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043276486.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043267455.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_043286412.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043275878.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-182218	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation"
XP_043283360.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043280649.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_043281429.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_043272247.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043279349.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_043272350.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism"
XP_043273505.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_043284011.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043285108.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_043274684.1	33	Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-8939236;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"HIV Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_043286152.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043271352.1	5	Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946	"Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants"
XP_043285358.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043283252.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_043281904.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043269064.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043288379.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_043268417.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_043288256.1	33	Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200	"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"HIV Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_043266568.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-196025	"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions"
XP_043282323.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_043285975.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043272599.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_043279437.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_043275148.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_043268551.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins"
XP_043267364.1	14	KEGG: 00770+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5076;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-7767;Reactome: R-HSA-70895;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5108	"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"L-leucine degradation III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V"
XP_043272359.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"RAF/MAP kinase cascade"
XP_043274186.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_043274564.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_043277584.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_043282312.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_043275751.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043270571.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043279577.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043270129.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_043269566.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043278844.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043266843.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043278798.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043272781.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043270785.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043283285.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043285336.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043275253.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043286889.1	4	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism"
XP_043269767.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_043271737.1	44	Reactome: R-HSA-5674499;Reactome: R-HSA-8943724;Reactome: R-HSA-444257;Reactome: R-HSA-9649948;Reactome: R-HSA-456926;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-450341;Reactome: R-HSA-9627069;Reactome: R-HSA-6802955;Reactome: R-HSA-202670;Reactome: R-HSA-74749;Reactome: R-HSA-375165;Reactome: R-HSA-2871796;Reactome: R-HSA-6802948;Reactome: R-HSA-5673001;Reactome: R-HSA-879415;Reactome: R-HSA-5654733;Reactome: R-HSA-112409;Reactome: R-HSA-982772;Reactome: R-HSA-2559582;Reactome: R-HSA-170968;KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-9634638;Reactome: R-HSA-2559580;Reactome: R-HSA-6802946;Reactome: R-HSA-881907;Reactome: R-HSA-198753;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-1295596;Reactome: R-HSA-6802952;Reactome: R-HSA-5668599;Reactome: R-HSA-8940973;Reactome: R-HSA-8939211;Reactome: R-HSA-5663213;Reactome: R-HSA-162658;Reactome: R-HSA-2559585;Reactome: R-HSA-5675221;Reactome: R-HSA-2029482;Reactome: R-HSA-9635465;Reactome: R-HSA-5674135;Reactome: R-HSA-445144	"Negative feedback regulation of MAPK pathway";"Regulation of PTEN gene transcription";"RSK activation";"Signaling downstream of RAS mutants";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Activation of the AP-1 family of transcription factors";"Regulation of the apoptosome activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ERKs are inactivated";"Signal attenuation";"NCAM signaling for neurite out-growth";"FCERI mediated MAPK activation";"Signaling by high-kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR4 signaling";"RAF-independent MAPK1/3 activation";"Growth hormone receptor signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Frs2-mediated activation";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Oxidative Stress Induced Senescence";"Signaling by moderate kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"ERK/MAPK targets";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Spry regulation of FGF signaling";"Signaling by BRAF and RAF fusions";"RHO GTPases Activate NADPH Oxidases";"RUNX2 regulates osteoblast differentiation";"ESR-mediated signaling";"RHO GTPases Activate WASPs and WAVEs";"Golgi Cisternae Pericentriolar Stack Reorganization";"Oncogene Induced Senescence";"Negative regulation of MAPK pathway";"Regulation of actin dynamics for phagocytic cup formation";"Suppression of apoptosis";"MAP2K and MAPK activation";"Signal transduction by L1"
XP_043282723.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_043276244.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903	"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy"
XP_043289205.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043288218.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043275755.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043290101.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043289596.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043276122.1	3	MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099	"L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling"
XP_043269176.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043276843.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043276684.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_043268354.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation"
XP_043267600.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_043282054.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043286646.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043286495.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043271516.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_043287233.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_043270784.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043271295.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043273036.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043281743.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043288679.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-179409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A"
XP_043268130.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I"
XP_043284017.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_043288918.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043282565.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_043281025.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-112043	"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"Regulation of insulin secretion";"PLC beta mediated events"
XP_043272378.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_043288223.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043282818.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043286231.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_043271281.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043273619.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_043269527.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043266672.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_043281075.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_043283134.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_043280795.1	17	Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167287	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery"
XP_043280552.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043283454.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043273756.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_043286418.1	3	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043281240.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043274286.1	6	Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Methane metabolism";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_043268356.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043280764.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884	"Ca2+ pathway";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX"
XP_043274961.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043271877.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_043282608.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry"
XP_043267624.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_043279247.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043270572.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043281586.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043280729.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_043280693.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043267769.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_043274465.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043278943.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043275754.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043282039.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043287057.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;Reactome: R-HSA-196836;MetaCyc: PWY-7112	"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification"
XP_043267395.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_043286081.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043287392.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_043276199.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_043285887.1	6	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_043274386.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785	"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome"
XP_043270014.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_043289097.1	6	KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165	"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_043280744.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043273960.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_043285353.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043273876.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043268923.1	7	KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074	"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Synthesis of Ketone Bodies";"Mevalonate degradation"
XP_043267369.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_043275730.1	4	MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14	"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism"
XP_043283031.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_043273579.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_043288736.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043268246.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043287931.1	17	MetaCyc: PWY-5532;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6644;MetaCyc: PWY-6620;Reactome: R-HSA-74259	"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Pyrimidine metabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Purine catabolism"
XP_043270227.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_043268260.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043280458.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043288104.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043274496.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787	"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state"
XP_043284848.1	5	KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68	"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_043287721.1	13	KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_043271658.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_043271570.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_043285478.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_043282637.1	5	KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Methionine salvage pathway";"Regulation of the apoptosome activity"
XP_043267360.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017	"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6"
XP_043274039.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043276920.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_043273383.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043267965.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_043271680.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_043278024.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_043288874.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_043286162.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043278866.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_043281040.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043268703.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043287967.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_043277483.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_043267146.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_043287209.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043283574.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043280266.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043268203.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_043272536.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_043278307.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043289354.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-918233;Reactome: R-HSA-381340	"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Attenuation phase";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_043279235.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043275056.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_043284335.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043281219.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043277264.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_043289900.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043267884.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043278596.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043272233.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_043278783.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_043269327.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_043288225.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043278050.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_043278575.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043269554.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_043288662.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_043275131.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043287256.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-165054	"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA"
XP_043272997.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043266404.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_043285348.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043286093.1	5	MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_043280553.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043277212.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_043280972.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_043268483.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043280298.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043267754.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_043273919.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_043281164.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_043272879.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_043272681.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043284851.1	5	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_043287930.1	17	MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1	"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Purine catabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Purine metabolism";"Pyrimidine metabolism"
XP_043286460.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043281165.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043289783.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043289942.1	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
XP_043271972.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_043273209.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_043269299.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043282319.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043287208.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Luteolin triglucuronide degradation";"Betanidin degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_043269797.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043283772.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043280831.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_043270109.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_043283080.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451	"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_043285362.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043277248.1	10	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Recycling pathway of L1";"mTOR signaling pathway";"RSK activation"
XP_043288399.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043279343.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043275986.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation"
XP_043274954.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_043289644.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278211.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631	"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility"
XP_043283065.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_043272659.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_043276270.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043280579.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043283369.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_043279528.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043275989.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043272886.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_043270299.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043269607.1	10	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5357956	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Regulation of TNFR1 signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"mTOR signaling pathway";"TNFR1-induced NFkappaB signaling pathway"
XP_043275175.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043278039.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_043270191.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043282191.1	3	KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis"
XP_043280973.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_043279149.1	1	KEGG: 00970+6.1.1.1	"Aminoacyl-tRNA biosynthesis"
XP_043286758.1	5	MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6	"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism"
XP_043275110.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043282329.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_043284885.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043269539.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_043272913.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043272216.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043269740.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043270215.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_043288032.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway"
XP_043269835.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_043284266.1	8	Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_043282647.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;MetaCyc: PWY-7511	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Protein ubiquitination"
XP_043275784.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25	"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_043268913.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_043280947.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)"
XP_043287921.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043271311.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043279448.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043283478.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_043278577.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001	"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade"
XP_043283616.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_043274205.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_043268713.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043278194.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043274101.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043269061.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043272148.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043271675.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_043275759.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043280651.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043268682.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043275428.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043268811.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_043287011.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_043286532.1	13	KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-6672;Reactome: R-HSA-71384;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108	"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Ethanol oxidation";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V"
XP_043279301.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043286207.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_043280931.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043267464.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_043278740.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043270667.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761	"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_043284577.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_043286424.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043273058.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043274680.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_043272355.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade"
XP_043288776.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043286514.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_043286422.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043275129.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043270362.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_043275740.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_043274210.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_043275996.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_043270070.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_043268509.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_043273380.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043277095.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043275758.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_043275471.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_043279822.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-202733;Reactome: R-HSA-216083;Reactome: R-HSA-391160	"Neutrophil degranulation";"Cell surface interactions at the vascular wall";"Integrin cell surface interactions";"Signal regulatory protein family interactions"
XP_043280502.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_043287391.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_043281076.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043271751.1	11	KEGG: 00230+1.17.1.4;MetaCyc: PWY-5497;MetaCyc: PWY-6999;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-6607;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6538;Reactome: R-HSA-8851680	"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Butyrophilin (BTN) family interactions"
XP_043286208.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043267466.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;Reactome: R-HSA-73817	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_043272983.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043269551.1	18	KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913	"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)"
XP_043280487.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_043272274.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043270674.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043283055.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043271938.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043288568.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_043282208.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_043283046.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043281196.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043278741.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043267857.1	10	Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111463	"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs"
XP_043272075.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_043269723.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043275877.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043273389.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043289884.1	29	Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-3108214;Reactome: R-HSA-5656121;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-110320	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HSF1 activation";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLI";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH"
XP_043279821.1	4	Reactome: R-HSA-202733;Reactome: R-HSA-6798695;Reactome: R-HSA-391160;Reactome: R-HSA-216083	"Cell surface interactions at the vascular wall";"Neutrophil degranulation";"Signal regulatory protein family interactions";"Integrin cell surface interactions"
XP_043280607.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043273272.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043288080.1	9	MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5744	"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation"
XP_043270263.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043279708.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043271431.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043286381.1	12	KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Galactose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism"
XP_043286097.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043272502.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043276487.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043285891.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043280765.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043280963.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043288727.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043287160.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_043279422.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-7442	"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis"
XP_043287707.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043271852.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_043287969.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043284002.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043267469.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_043282294.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043278857.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043286297.1	8	MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581	"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Tyrosine metabolism";"Catecholamine biosynthesis";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"(S)-reticuline biosynthesis I"
XP_043275011.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043280036.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_043286455.1	11	KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;MetaCyc: PWY-6964;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2	"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Nitrogen metabolism"
XP_043276610.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043285695.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043273387.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043272213.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043288406.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043281897.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_043282815.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043282978.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_043272943.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043267456.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_043286852.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043268364.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043279823.1	4	Reactome: R-HSA-202733;Reactome: R-HSA-6798695;Reactome: R-HSA-391160;Reactome: R-HSA-216083	"Cell surface interactions at the vascular wall";"Neutrophil degranulation";"Signal regulatory protein family interactions";"Integrin cell surface interactions"
XP_043279165.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043281313.1	9	Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11	"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism"
XP_043281314.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043283513.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_043283295.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043266406.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_043282065.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_043284255.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_043287899.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_043283125.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043284889.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043273601.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043268764.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043283399.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043284732.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_043276639.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043271826.1	11	MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism"
XP_043276283.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_043287476.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_043289478.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_043272063.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_043267547.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_043282367.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043272685.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_043267006.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_043272981.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043281982.1	3	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression"
XP_043275437.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_043270008.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_043283911.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_043273981.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043285965.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_043273282.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043282764.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043275988.1	5	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_043289372.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043272511.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043286848.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043288642.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043280835.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_043279222.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_043272584.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043281789.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043272470.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043272289.1	6	Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537	"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_043289131.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_043275561.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043283703.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043288035.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_043271733.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_043280819.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043284610.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043277837.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043279293.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_043288513.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043282852.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043279296.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043266897.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_043270228.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_043286177.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043272408.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043280377.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043285019.1	42	Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-73728;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110328;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-5625886;Reactome: R-HSA-3214858;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-171306;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-110330	"Processing of DNA double-strand break ends";"HCMV Late Events";"PRC2 methylates histones and DNA";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"RNA Polymerase I Promoter Opening";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RMTs methylate histone arginines";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_043269561.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043277993.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_043270254.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043273695.1	33	MetaCyc: PWY-5078;MetaCyc: PWY-5076;KEGG: 00980+1.1.1.1;Reactome: R-HSA-71384;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5486;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5082;MetaCyc: PWY-6313;MetaCyc: PWY-7118;MetaCyc: PWY-7013;MetaCyc: PWY-5057;MetaCyc: PWY-6802;MetaCyc: PWY-6587;MetaCyc: PWY-6871;KEGG: 00010+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00260+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00830+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-1801;MetaCyc: PWY-5751;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-5079	"L-isoleucine degradation II";"L-leucine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Ethanol oxidation";"Naphthalene degradation";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol II";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to isobutanol (engineered)";"L-methionine degradation III";"Serotonin degradation";"Chitin degradation to ethanol";"(S)-propane-1,2-diol degradation";"L-valine degradation II";"Salidroside biosynthesis";"Pyruvate fermentation to ethanol III";"3-methylbutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol I";"Drug metabolism - cytochrome P450";"Butanol and isobutanol biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"Tyrosine metabolism";"Acetaldehyde biosynthesis I";"Retinol metabolism";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Phenylethanol biosynthesis";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"Protein S-nitrosylation and denitrosylation";"L-phenylalanine degradation III"
XP_043273746.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism"
XP_043270776.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_043270573.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043274993.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-114604	"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade"
XP_043283010.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_043276346.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_043272253.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043278501.1	22	MetaCyc: PWY-5514;KEGG: 00500+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-5659;MetaCyc: PWY-8013;Reactome: R-HSA-6798695;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.9;MetaCyc: PWY-621;MetaCyc: PWY-5384;MetaCyc: PWY-6992;Reactome: R-HSA-5628897;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-7347;MetaCyc: PWY-622;MetaCyc: PWY-6981;MetaCyc: PWY-5054;MetaCyc: PWY-7238;MetaCyc: PWY-7385;KEGG: 00520+5.3.1.9;KEGG: 00030+5.3.1.9	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Neutrophil degranulation";"Glycolysis";"Glycolysis / Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation IV (sucrose phosphorylase)";"1,5-anhydrofructose degradation";"TP53 Regulates Metabolic Genes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Sucrose biosynthesis III";"Starch biosynthesis";"Chitin biosynthesis";"D-sorbitol biosynthesis I";"Sucrose biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway"
XP_043275380.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379	"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres"
XP_043270859.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043274264.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043287937.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043270763.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_043274085.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043273945.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_043281026.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921	"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Ca2+ pathway";"Regulation of insulin secretion";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation"
XP_043269188.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043285182.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043276967.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-110362	"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair"
XP_043283899.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043270527.1	5	Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397	"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_043285481.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_043268323.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_043270825.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043269541.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_043272896.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events"
XP_043286239.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_043279026.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_043275177.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043275410.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043270851.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043286404.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043268367.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043277393.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_043269971.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043268230.1	3	MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_043278893.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes"
XP_043272095.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_043280935.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043283720.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043275722.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043281056.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043275212.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_043266481.1	5	Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_043270163.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043278574.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043267439.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_043283946.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043281204.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043281059.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043267833.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_043287738.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_043281784.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_043273464.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043287125.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043285324.1	15	Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939	"Processing of DNA double-strand break ends";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)"
XP_043278143.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_043266708.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043285920.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_043287875.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043284557.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043284556.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043279087.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"