Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_035724366.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035723273.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_035739878.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035718605.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035720367.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_035733270.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035718708.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035730217.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035717684.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_035718754.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035725906.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_035723465.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_035736690.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_035722585.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs"
XP_035727877.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035738003.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035738302.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035720208.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035722162.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_035719546.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035721305.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_035734973.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035718514.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035731534.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035726925.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_035739255.1	10	KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_035741744.1	17	Reactome: R-HSA-69205;Reactome: R-HSA-2559585;Reactome: R-HSA-139915;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-113501;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-8953750;Reactome: R-HSA-69231;Reactome: R-HSA-111448;Reactome: R-HSA-69202;Reactome: R-HSA-9616222;Reactome: R-HSA-1362277	"G1/S-Specific Transcription";"Oncogene Induced Senescence";"Activation of PUMA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional Regulation by E2F6";"Cyclin D associated events in G1";"Activation of NOXA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Transcriptional regulation of granulopoiesis";"Transcription of E2F targets under negative control by DREAM complex"
XP_035726164.1	13	KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9	"One carbon pool by folate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Folate transformations I";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"One carbon pool by folate"
XP_035725036.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035720393.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035728287.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035724843.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035720613.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035739796.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035735059.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035719381.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_035739519.1	5	MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;MetaCyc: PWY-5523;Reactome: R-HSA-196843;MetaCyc: PWY-7863	"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis"
XP_035729761.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035723050.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
XP_035724198.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035726012.1	16	Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-114604	"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"G alpha (q) signalling events";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"RET signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade"
XP_035730610.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035733677.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
YP_009915662.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035728371.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035739412.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_035733053.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035736297.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-2162123;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_035728967.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035725678.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids"
XP_035726309.1	4	KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_035720150.1	13	Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-168638	"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway"
XP_035743884.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_035730333.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_035721501.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035739503.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035735096.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035734446.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035717972.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035720609.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035728993.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736263.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_035737753.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_035738683.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035721594.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_035741383.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035733132.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035729948.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035730841.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_035730153.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035726260.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035742412.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_035731797.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_035726576.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035742998.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;MetaCyc: PWY-7511	"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Protein ubiquitination"
XP_035718061.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_035742232.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035729969.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Laminin interactions"
XP_035737729.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035724545.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035735322.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4	"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_035742805.1	13	Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-182218	"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation"
XP_035737815.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035734148.1	5	MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_035718775.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035743689.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035726221.1	29	Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_035742723.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_035739951.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035724712.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035721747.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035730866.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035742662.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_035740257.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035739805.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035743692.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035738757.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035718678.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_035722536.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_035720497.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035738943.1	12	MetaCyc: PWY-5872;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;MetaCyc: PWY-5870;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-6708;Reactome: R-HSA-2142789	"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
XP_035734461.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035732703.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_035726626.1	13	KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;Reactome: R-HSA-416482	"Relaxin signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events"
XP_035736454.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation"
XP_035717944.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_035735717.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035722883.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035726640.1	8	Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922	"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_035723718.1	8	Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756	"Lipophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation"
XP_035732559.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_035719700.1	8	Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035723615.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6798695	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Neutrophil degranulation"
XP_035722700.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_035718036.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035731171.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719	"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"RAF activation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors"
XP_035727179.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035735557.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035717710.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_035727283.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035732719.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035730343.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_035733566.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035729289.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035742170.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035732486.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900	"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_035719561.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_035740650.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription"
XP_035718279.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035729292.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035741487.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035733142.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035743939.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035720340.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035741597.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_035737280.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035724327.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_035729938.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035723720.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_035717993.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-69017	"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6"
XP_035728972.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035724251.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_035741379.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035743215.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_035742029.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation"
XP_035732692.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_035726849.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_035731975.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_035728058.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035736601.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-383280;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-212436	"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway"
XP_035733274.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035717680.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_035735960.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035726984.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035738679.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035732689.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035722999.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_035721533.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035730301.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035728934.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_035720250.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111459	"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Neutrophil degranulation";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage"
XP_035723785.1	12	Reactome: R-HSA-1839117;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1	"Signaling by cytosolic FGFR1 fusion mutants";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"Signaling by FGFR1 in disease";"Rho GTPase cycle";"Relaxin signaling pathway"
XP_035734269.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion"
XP_035739029.1	9	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_035730394.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035732727.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_035719956.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_035724002.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_035741726.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035718510.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035717967.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035731530.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035717625.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035730253.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_035733998.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_035723688.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_035724319.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_035740675.1	6	Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035723173.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035731567.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_035723008.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_035742335.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_035717930.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_035730614.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035720372.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035742566.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_035734238.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035725179.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_035740778.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035724682.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035725283.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035743880.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035719674.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035720657.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV"
XP_035739142.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_035720108.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035729887.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035734424.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_035734668.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035740347.1	7	Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-5689880	"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"Ub-specific processing proteases"
XP_035732009.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_035743559.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_035729504.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_035720334.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035739566.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_035725018.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035718877.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-389513	"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling"
XP_035735280.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035731593.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035743445.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_035736206.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_035721845.1	9	Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066	"Long-term potentiation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_035730070.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035728187.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035723736.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035734781.1	14	MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1	"Glycine betaine degradation I";"Methane metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate polyglutamylation";"Photorespiration ";"Glycine, serine and threonine metabolism"
XP_035730725.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035724894.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_035740088.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035732731.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_035742541.1	10	Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-8936459	"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035725471.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035739270.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035743523.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_035724407.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Pyruvate metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I"
XP_035724955.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035725877.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_035743911.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740213.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035729273.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042	"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Methane metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_035727279.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035727906.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_035720406.1	3	Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_035733255.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035728944.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035731895.1	15	Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)"
XP_035739541.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035742527.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_035720783.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_035729916.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035727036.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035731526.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035733242.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_035728889.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035740976.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035731540.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035725024.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis"
XP_035740209.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035722879.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035737059.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_035717508.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035735513.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_035719791.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-165054	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA"
XP_035721051.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035726644.1	10	KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis"
XP_035739386.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_035719704.1	8	Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035741928.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035726453.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035733519.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035722642.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035744199.1	11	MetaCyc: PWY-5695;KEGG: 00230+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-7821;MetaCyc: PWY-6606;MetaCyc: PWY-5381;MetaCyc: PWY-6608;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596	"Inosine 5'-phosphate degradation";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Pyrimidine metabolism";"Adenosine nucleotides degradation I"
XP_035730229.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha"
XP_035733796.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035738874.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035717714.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035735947.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_035739345.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035740337.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035735509.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_035740443.1	6	MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Pentose phosphate pathway"
XP_035721202.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035723948.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_035723500.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035726868.1	29	Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-73779	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_035731387.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035725750.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7	"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis"
XP_035738027.1	31	MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-6282;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWY-8047;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-4381;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-5142;Reactome: R-HSA-199220	"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism"
XP_035733759.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035723075.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_035734872.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035741793.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035730403.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035737152.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_035739276.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_035717265.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035728716.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_035730745.1	7	KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_035740535.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035723730.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035744089.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035728599.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_035724922.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035721188.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035727548.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035740366.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035728582.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035731585.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035737145.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_035736777.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310	"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway"
XP_035730648.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035731162.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955	"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Signaling downstream of RAS mutants";"Long-term potentiation";"Interferon gamma signaling";"Ion homeostasis";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_035734787.1	14	KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201	"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Photorespiration ";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Methane metabolism";"Glycine betaine degradation I";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Folate transformations I"
XP_035732737.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_035730864.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035725477.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035724807.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035737919.1	7	Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2	"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_035732305.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736348.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035739039.1	9	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)"
XP_035742547.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels"
XP_035743917.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035722534.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_035727612.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035731546.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035725871.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_035740970.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035726439.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035729865.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_035725044.1	52	Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785	"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Degradation of DVL";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome"
XP_035740331.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035741075.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035727067.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035739380.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035734472.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035735941.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_035735802.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_035717920.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy"
XP_035722763.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_035726127.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035725782.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035736456.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_035718034.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035719763.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_035738021.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035741948.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035730249.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035731381.1	19	MetaCyc: PWY-6728;Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;Reactome: R-HSA-71403;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-5538	"Methylaspartate cycle";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI"
XP_035735235.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035734228.1	6	KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22	"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism"
XP_035719797.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_035738474.1	22	MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7592;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7726;Reactome: R-HSA-75876;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7606;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_035742380.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035721057.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035735665.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035734434.1	8	KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1	"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism"
XP_035733564.1	8	KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5154;MetaCyc: PWY-4983;MetaCyc: PWY-4984;MetaCyc: PWY-7400;MetaCyc: PWY-5	"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis"
XP_035732484.1	7	MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7185	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I"
XP_035723928.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035740423.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035726853.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035739671.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_035744150.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035736592.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035729099.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_035718904.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035722797.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5578749	"Nuclear import of Rev protein";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs"
XP_035733812.1	5	Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755579	"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_035735768.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035736850.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_035723740.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035738060.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-2029482	"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_035720299.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035724364.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_035723726.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035730735.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035732721.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035733405.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035737135.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035728063.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_035737342.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_035732378.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035741785.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035720282.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035717686.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_035725904.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_035719950.1	16	Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8856828	"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"LDL clearance";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Gap junction degradation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis"
XP_035737043.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035739049.1	9	KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_035736338.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895	"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Degradation of DVL";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis"
XP_035718782.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035730268.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids"
XP_035728362.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
YP_009915671.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_035718799.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035726166.1	13	KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-6613	"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"One carbon pool by folate";"L-histidine degradation III";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_035738212.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035725034.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035727040.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035736191.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035722544.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035718516.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035731536.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035721445.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035719016.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_035742122.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035724113.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035721559.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035740341.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035738442.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_035726219.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-674695	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events"
XP_035731883.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035739794.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation"
XP_035734110.1	11	Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604	"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"PIP3 activates AKT signaling"
XP_035735245.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035721880.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035741938.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035742560.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_035740833.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_035729597.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_035739122.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035728918.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035730669.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_035721596.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035735001.1	26	Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Cilium Assembly";"Gap junction assembly";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion"
XP_035743886.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_035727569.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_035731561.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035734444.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035735094.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035730111.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_035736200.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035730076.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_035717281.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_035739560.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035721825.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_035734077.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_035743425.1	12	Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"NRAGE signals death through JNK";"Relaxin signaling pathway";"G alpha (q) signalling events";"Rho GTPase cycle"
XP_035727462.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035731982.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_035719048.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_035723734.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035721741.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_035739405.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_035724896.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035720458.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035735342.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035743747.1	13	MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5537	"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V"
XP_035726005.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_035738751.1	8	KEGG: 00030+5.3.1.6;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6	"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_035720491.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_035737415.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035730915.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange"
XP_035728946.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730860.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035718392.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_035732533.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_035723772.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_035742405.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035743721.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035722530.1	4	Reactome: R-HSA-4755609;MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_035731956.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035728769.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_035727034.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035724490.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_035739384.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035726646.1	10	MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11	"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism"
XP_035739176.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035719706.1	8	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035717165.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_035730431.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)"
XP_035735488.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035735598.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035723487.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_035717556.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035740682.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035741558.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035741481.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035723881.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035730022.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_035730837.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_035735711.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035725569.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035733560.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035717716.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035721009.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_035728265.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035717489.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_035726788.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_035738315.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_035744154.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035741718.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035744108.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035717492.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035731674.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035744073.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"HDMs demethylate histones"
XP_035721312.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035718900.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035733122.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035718548.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035732845.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035740407.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035723744.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035740955.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035719271.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_035735152.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_035724360.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_035726119.1	56	Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253	"Degradation of AXIN";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of DVL";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex"
XP_035732917.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_035733547.1	52	Reactome: R-HSA-749476;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-5250924;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-113418	"RNA Polymerase III Abortive And Retractive Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"B-WICH complex positively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex"
XP_035736696.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035740894.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035724088.1	3	KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383	"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism"
XP_035722038.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_035726661.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035728281.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035743737.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_035742478.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_035730139.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_035730396.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_035741465.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035742733.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243	"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035723865.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035735919.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035718195.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035726103.1	11	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-110314	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex"
XP_035723910.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035720361.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_035728936.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_035722895.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035733913.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035730211.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035717181.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035731879.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_035741724.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035725612.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035739478.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_035722908.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_035727871.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035732051.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_035724823.1	9	MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism"
XP_035728748.1	8	KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27	"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Pyruvate metabolism"
XP_035717362.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_035742812.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_035723383.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035725067.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_035734114.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035737235.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_035731758.1	6	Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36	"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_035729793.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_035731791.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035718040.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_035742564.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_035738959.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035727799.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035743501.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_035743760.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_035729767.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_035735090.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035730168.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035736204.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035733671.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948	"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants"
XP_035728686.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_035741050.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_035734885.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035737768.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035718538.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035732835.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035728961.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035729506.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_035720336.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035725093.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035731792.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035741200.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035724964.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035734279.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_035732045.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035743502.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_035735535.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_035743409.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_035730442.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)"
XP_035729408.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035737942.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_035732052.1	10	Reactome: R-HSA-442742;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035726170.1	13	MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757	"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"One carbon pool by folate";"One carbon pool by folate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines"
XP_035742811.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_035717361.1	7	Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693571	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)"
XP_035736292.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_035728962.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
YP_009915667.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035733672.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035736938.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035719350.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035731627.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035731810.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035723206.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035726017.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035738669.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_035743413.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035739811.1	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_035732294.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_035726662.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736746.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_035728282.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035741104.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035741607.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_035725840.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_035718461.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035720063.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035741191.1	13	KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-7118;Reactome: R-HSA-71384;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1	"Pyruvate metabolism";"Propanoate metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Ethanol oxidation";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis"
XP_035725595.1	14	KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-5690;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-7279	"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_035739576.1	6	KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_035717565.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035735151.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_035738735.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035723197.1	18	Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035724059.1	5	KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074	"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Mevalonate degradation"
XP_035736969.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738307.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_035735198.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_035722664.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_035719272.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_035725611.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_035727872.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035718893.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_035740665.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_035730212.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201	"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis"
XP_035717182.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035726998.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035738268.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035720362.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_035725169.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex"
XP_035720097.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035739221.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035719234.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035717863.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035731631.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035733702.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_035742313.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035741482.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035729297.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035723882.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035735459.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_035741850.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710	"SUMOylation of transcription cofactors";"Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy"
XP_035723450.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035726796.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035737298.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_035740681.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237	"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2"
XP_035727300.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_035726519.1	12	Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_035721259.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_035722869.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_035737932.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035740966.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035735552.1	7	MetaCyc: PWY-7807;MetaCyc: PWY-6610;MetaCyc: PWY-7805;Reactome: R-HSA-74217;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;Reactome: R-HSA-6798695	"Glyphosate degradation III";"Adenine salvage";"(aminomethyl)phosphonate degradation";"Purine salvage";"Adenine and adenosine salvage II";"Purine metabolism";"Neutrophil degranulation"
XP_035739313.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_035718840.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035733121.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035735496.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_035732457.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035732905.1	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836;MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_035742309.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035739260.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis"
XP_035722140.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035725461.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035717491.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035726503.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035742630.1	31	MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-4381;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5989;MetaCyc: PWY-6519;Reactome: R-HSA-75105;MetaCyc: PWY-8049	"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis"
XP_035729310.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_035718595.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035731261.1	5	MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344	"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_035733868.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035735712.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035740370.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035726759.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035737974.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_035731079.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035732329.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035744000.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035720492.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_035720582.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035735341.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035728400.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_035736736.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426496	"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs"
XP_035727844.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_035742164.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_035721604.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_035721107.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_035721658.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035738745.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035731981.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_035738403.1	7	MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-7886	"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_035738512.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035734754.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035718138.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035734708.1	19	Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-983231;Reactome: R-HSA-5627123;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-114604;Reactome: R-HSA-2029482	"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate PAKs";"EGFR downregulation";"Rho GTPase cycle";"Myogenesis";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation"
XP_035739667.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-6804756	"Activation of AMPK downstream of NMDARs";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation"
XP_035740094.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035741777.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_035739164.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_035723771.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events"
XP_035738786.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035744287.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035718304.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035727668.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_035732776.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035734605.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035719267.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158	"Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V"
XP_035724815.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_035737459.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035741204.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_035732317.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035735303.1	24	Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;Reactome: R-HSA-5218921	"RHO GTPases activate PKNs";"Integrin signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Relaxin signaling pathway";"RSK activation";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"mTOR signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation"
XP_035733012.1	19	MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380320;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_035742868.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035739453.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade"
XP_035727148.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_035724960.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_035733630.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_035725639.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035740355.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035735251.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035740342.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035738441.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_035726053.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035733309.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-5621575	"Circadian Clock";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling"
XP_035724729.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035735932.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_035743905.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_035741316.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_035721857.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_035742121.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035739702.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035724687.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035724376.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035734997.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035722637.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035742453.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035724184.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035727461.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035718248.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035740043.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_035738821.1	11	MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6969	"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Glutathione metabolism";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_035723310.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_035720377.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035720686.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537	"HDACs deacetylate histones";"HCMV Early Events";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_035719293.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035738168.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035722308.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_035722354.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_035726345.1	10	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Regulation of TNFR1 signaling";"T cell receptor signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035728156.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA"
XP_035727867.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035742147.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035742644.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035735002.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467	"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs"
XP_035719134.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_035733313.1	26	Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-210744	"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Circadian Clock";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_035737341.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_035725844.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_035729065.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337	"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding"
XP_035720281.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_035733693.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035725116.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619	"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN"
XP_035736724.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism"
XP_035738359.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035739839.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_035732722.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_035722660.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_035736192.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035719987.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035725765.1	5	KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035729771.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_035731773.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862	"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035718781.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035723106.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;Reactome: R-HSA-446205	"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose"
XP_035720936.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035733667.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation"
YP_009915672.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035724937.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035736189.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035725668.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_035717698.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_035728977.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035739357.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_035735955.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_035727216.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035733640.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035735407.1	24	Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-420092	"G alpha (q) signalling events";"G alpha (s) signalling events";"G alpha (z) signalling events";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors"
XP_035721025.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035743294.1	4	Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Unwinding of DNA"
XP_035734877.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035725649.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events"
XP_035736718.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035741808.1	19	MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37	"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Methylaspartate cycle";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Methane metabolism"
XP_035738022.1	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_035727138.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035723454.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035741854.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_035739137.1	11	KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7206	"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_035731399.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035720738.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_035725781.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035718668.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035727304.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_035743353.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035727358.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035734471.1	8	KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1	"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism"
XP_035735801.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_035736615.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035721080.1	179	Reactome: R-HSA-3769402;Reactome: R-HSA-9615710;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-2173795;Reactome: R-HSA-5689896;Reactome: R-HSA-1253288;Reactome: R-HSA-72706;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-6782135;Reactome: R-HSA-168927;Reactome: R-HSA-5654733;Reactome: R-HSA-3322077;Reactome: R-HSA-2467813;Reactome: R-HSA-400253;Reactome: R-HSA-72764;Reactome: R-HSA-5362768;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-205043;Reactome: R-HSA-4608870;Reactome: R-HSA-9646399;Reactome: R-HSA-8854050;Reactome: R-HSA-5696394;Reactome: R-HSA-975956;Reactome: R-HSA-6781827;Reactome: R-HSA-8876493;Reactome: R-HSA-937041;Reactome: R-HSA-8939902;Reactome: R-HSA-6804760;Reactome: R-HSA-5689880;Reactome: R-HSA-2173788;Reactome: R-HSA-5656169;Reactome: R-HSA-9033241;Reactome: R-HSA-4641258;Reactome: R-HSA-5654732;Reactome: R-HSA-6782210;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-2173791;Reactome: R-HSA-450302;Reactome: R-HSA-5696395;Reactome: R-HSA-5654726;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-156902;Reactome: R-HSA-8939236;Reactome: R-HSA-977225;Reactome: R-HSA-9010553;Reactome: R-HSA-8849469;Reactome: R-HSA-450408;Reactome: R-HSA-5654727;Reactome: R-HSA-5655862;Reactome: R-HSA-174048;Reactome: R-HSA-8948751;Reactome: R-HSA-5693607;Reactome: R-HSA-937039;Reactome: R-HSA-5607761;Reactome: R-HSA-8948747;Reactome: R-HSA-1799339;Reactome: R-HSA-211733;Reactome: R-HSA-8875360;Reactome: R-HSA-174113;Reactome: R-HSA-6791226;Reactome: R-HSA-8863795;Reactome: R-HSA-6783310;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-901032;Reactome: R-HSA-2559585;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-2122947;Reactome: R-HSA-168638;Reactome: R-HSA-3134975;Reactome: R-HSA-201681;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69541;Reactome: R-HSA-975144;Reactome: R-HSA-2979096;Reactome: R-HSA-937042;Reactome: R-HSA-180534;Reactome: R-HSA-1236382;Reactome: R-HSA-1295596;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8856825;Reactome: R-HSA-912631;Reactome: R-HSA-975163;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-4641263;Reactome: R-HSA-5689877;Reactome: R-HSA-162588;Reactome: R-HSA-187577;Reactome: R-HSA-532668;Reactome: R-HSA-202424;Reactome: R-HSA-1358803;Reactome: R-HSA-2122948;Reactome: R-HSA-1169408;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-72689;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-9637628;Reactome: R-HSA-9013507;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-5685942;Reactome: R-HSA-9604323;Reactome: R-HSA-110320;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-8856828;Reactome: R-HSA-6781823;Reactome: R-HSA-9013973;Reactome: R-HSA-110312;Reactome: R-HSA-5632684;Reactome: R-HSA-5696400;Reactome: R-HSA-5675221;Reactome: R-HSA-2173796;Reactome: R-HSA-5610785;Reactome: R-HSA-5656121;Reactome: R-HSA-936440;Reactome: R-HSA-6804757;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-192823;Reactome: R-HSA-9636383;Reactome: R-HSA-1169091;Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-6804756;Reactome: R-HSA-975957;Reactome: R-HSA-936964;Reactome: R-HSA-9645460;Reactome: R-HSA-156827;Reactome: R-HSA-917729;Reactome: R-HSA-4641257;Reactome: R-HSA-5693565;Reactome: R-HSA-917937;Reactome: R-HSA-5358346;Reactome: R-HSA-3785653;Reactome: R-HSA-2565942;Reactome: R-HSA-110314;Reactome: R-HSA-5684264;Reactome: R-HSA-69017;Reactome: R-HSA-5689901;Reactome: R-HSA-175474;Reactome: R-HSA-5668541;Reactome: R-HSA-174490;Reactome: R-HSA-2691232;Reactome: R-HSA-174184;Reactome: R-HSA-5357905;Reactome: R-HSA-2559580;Reactome: R-HSA-9613829;Reactome: R-HSA-2672351;Reactome: R-HSA-5696397;Reactome: R-HSA-168928;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-2644606;Reactome: R-HSA-6807004;Reactome: R-HSA-1236974;Reactome: R-HSA-5675482;Reactome: R-HSA-8951664;Reactome: R-HSA-8866652	"Deactivation of the beta-catenin transactivating complex";"Late endosomal microautophagy";"EGFR downregulation";"Selenocysteine synthesis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Ovarian tumor domain proteases";"Downregulation of ERBB4 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Dual incision in TC-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"Negative regulation of FGFR4 signaling";"Glycogen synthesis";"Separation of Sister Chromatids";"Circadian Clock";"Eukaryotic Translation Termination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NRIF signals cell death from the nucleus";"Asymmetric localization of PCP proteins";"Aggrephagy";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"DNA Damage Recognition in GG-NER";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"InlA-mediated entry of Listeria monocytogenes into host cells";"IKK complex recruitment mediated by RIP1";"Regulation of RUNX2 expression and activity";"Regulation of TP53 Activity through Methylation";"Ub-specific processing proteases";"Downregulation of TGF-beta receptor signaling";"Termination of translesion DNA synthesis";"Peroxisomal protein import";"Degradation of DVL";"Negative regulation of FGFR3 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"activated TAK1 mediates p38 MAPK activation";"Formation of Incision Complex in GG-NER";"Negative regulation of FGFR1 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Peptide chain elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Amyloid fiber formation";"Regulation of expression of SLITs and ROBOs";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of FGFR2 signaling";"Translesion synthesis by POLK";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of PTEN stability and activity";"Processing of DNA double-strand break ends";"IRAK1 recruits IKK complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN localization";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"InlB-mediated entry of Listeria monocytogenes into host cell";"SCF-beta-TrCP mediated degradation of Emi1";"Major pathway of rRNA processing in the nucleolus and cytosol";"Downregulation of ERBB2 signaling";"Fanconi Anemia Pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER Quality Control Compartment (ERQC)";"Oncogene Induced Senescence";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOTCH1 Intracellular Domain Regulates Transcription";"NOD1/2 Signaling Pathway";"Regulation of innate immune responses to cytosolic DNA";"TCF dependent signaling in response to WNT";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Stabilization of p53";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"Vpu mediated degradation of CD4";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Spry regulation of FGF signaling";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of signaling by CBL";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of FZD by ubiquitination";"Josephin domain DUBs";"Budding and maturation of HIV virion";"SCF(Skp2)-mediated degradation of p27/p21";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downstream TCR signaling";"Downregulation of ERBB2:ERBB3 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"ISG15 antiviral mechanism";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"Formation of a pool of free 40S subunits";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Modulation by Mtb of host immune system";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"HDR through Homologous Recombination (HRR)";"Negative regulation of NOTCH4 signaling";"Translesion Synthesis by POLH";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"TICAM1-dependent activation of IRF3/IRF7";"Translesion synthesis by REV1";"Hedgehog 'on' state";"Dual Incision in GG-NER";"Negative regulation of MAPK pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"GLI3 is processed to GLI3R by the proteasome";"Translesion synthesis by POLI";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Degradation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"Viral mRNA Translation";"Prevention of phagosomal-lysosomal fusion";"Activation of NF-kappaB in B cells";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Alpha-protein kinase 1 signaling pathway";"L13a-mediated translational silencing of Ceruloplasmin expression";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Degradation of AXIN";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Iron uptake and transport";"Hedgehog ligand biogenesis";"Myoclonic epilepsy of Lafora";"Regulation of PLK1 Activity at G2/M Transition";"Recognition of DNA damage by PCNA-containing replication complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CDK-mediated phosphorylation and removal of Cdc6";"Metalloprotease DUBs";"Assembly Of The HIV Virion";"TNFR2 non-canonical NF-kB pathway";"Membrane binding and targetting of GAG proteins";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of TNFR1 signaling";"Oxidative Stress Induced Senescence";"Chaperone Mediated Autophagy";"Stimuli-sensing channels";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of MET activity";"ER-Phagosome pathway";"Regulation of necroptotic cell death";"Neddylation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_035718844.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035722816.1	39	Reactome: R-HSA-5673001;Reactome: R-HSA-190322;Reactome: R-HSA-1839122;Reactome: R-HSA-190372;Reactome: R-HSA-1839130;Reactome: R-HSA-5654706;Reactome: R-HSA-190375;Reactome: R-HSA-8853338;Reactome: R-HSA-5655302;Reactome: R-HSA-5654227;Reactome: R-HSA-1257604;Reactome: R-HSA-5654727;Reactome: R-HSA-5654689;Reactome: R-HSA-5654695;Reactome: R-HSA-109704;Reactome: R-HSA-5654710;Reactome: R-HSA-2033514;Reactome: R-HSA-2033519;Reactome: R-HSA-5654700;Reactome: R-HSA-5654687;Reactome: R-HSA-5654733;Reactome: R-HSA-5654726;Reactome: R-HSA-190373;Reactome: R-HSA-2219530;Reactome: R-HSA-5654688;Reactome: R-HSA-5654693;Reactome: R-HSA-5658623;Reactome: R-HSA-190371;Reactome: R-HSA-5654228;Reactome: R-HSA-5654704;Reactome: R-HSA-5654720;Reactome: R-HSA-5654712;Reactome: R-HSA-5654219;Reactome: R-HSA-5654699;Reactome: R-HSA-5654732;Reactome: R-HSA-5654719;Reactome: R-HSA-5655253;Reactome: R-HSA-6811558;Reactome: R-HSA-5654221	"RAF/MAP kinase cascade";"FGFR4 ligand binding and activation";"Signaling by activated point mutants of FGFR1";"FGFR3c ligand binding and activation";"Signaling by activated point mutants of FGFR3";"FRS-mediated FGFR3 signaling";"FGFR2c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade, FGFR3";"PIP3 activates AKT signaling";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR1";"PI-3K cascade:FGFR2";"PI3K Cascade";"PI-3K cascade:FGFR3";"FGFR3 mutant receptor activation";"Activated point mutants of FGFR2";"FRS-mediated FGFR2 signaling";"Downstream signaling of activated FGFR1";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR1 signaling";"FGFRL1 modulation of FGFR1 signaling";"FGFR3b ligand binding and activation";"Phospholipase C-mediated cascade, FGFR4";"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR4";"FRS-mediated FGFR4 signaling";"Phospholipase C-mediated cascade: FGFR1";"SHC-mediated cascade:FGFR2";"Negative regulation of FGFR3 signaling";"SHC-mediated cascade:FGFR4";"Signaling by FGFR2 in disease";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2"
XP_035731218.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_035727973.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035743978.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_035720473.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035722647.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035718992.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_035731136.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"snRNP Assembly";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase"
XP_035736591.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035732409.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035719144.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-6708	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_035742634.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_035740374.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_035733417.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035721368.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_035742429.1	7	MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_035734510.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_035744004.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035731603.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035727826.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035728404.1	9	MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_035729197.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035738466.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_035738149.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035721339.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035725834.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_035728581.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035721600.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_035720985.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_035724921.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035731448.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_035737151.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035737843.1	17	MetaCyc: PWY-5695;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-5532;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608	"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Pyrimidine metabolism";"Guanosine nucleotides degradation III"
XP_035743606.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation"
XP_035737423.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035733221.1	4	Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11	"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis"
XP_035734750.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035730923.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_035720769.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035727611.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035739160.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035740090.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035725872.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_035724947.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4	"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism"
XP_035726029.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_035720920.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035718300.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035719240.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035731161.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719	"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Signaling downstream of RAS mutants";"Long-term potentiation";"Interferon gamma signaling";"Ion homeostasis";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors"
XP_035724509.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257	"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion"
XP_035742849.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035727446.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035720946.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_035733817.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434	"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035718653.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I"
XP_035719416.1	12	KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13	"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Gluconeogenesis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism"
XP_035730870.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035727363.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035719789.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Activation of RAC1"
XP_035722792.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-180746	"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein"
XP_035743368.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_035738042.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_035727210.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035725818.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035718077.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035722641.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035721978.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035738055.1	18	MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes"
XP_035732809.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_035740964.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035743080.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035739219.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035722789.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_035719792.1	8	Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035721052.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035724739.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035739351.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_035718110.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035734871.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035739398.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035741643.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035734044.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_035735494.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_035743207.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_035731350.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035721201.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035739203.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035741454.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035740180.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035727397.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035737976.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_035721294.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_035725579.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-191859	"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"snRNP Assembly"
XP_035736734.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944	"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2"
XP_035733570.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035727846.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035734799.1	12	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange"
XP_035742449.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035742166.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_035727114.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-389661	"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation"
XP_035727820.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
XP_035722285.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_035742555.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035742542.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-400206	"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha"
XP_035725472.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_035719285.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035721606.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035737823.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035731428.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035744063.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035731167.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"HSF1-dependent transactivation";"Ion homeostasis";"Interferon gamma signaling";"Long-term potentiation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors"
XP_035732732.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_035739829.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035733241.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_035731234.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035729607.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_035739449.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035739166.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_035718214.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-7717;MetaCyc: PWY-5651	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
XP_035722246.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035734756.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035744097.1	8	MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6664;MetaCyc: PWY-2301;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_035735015.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035728587.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035727885.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035724768.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035722220.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035739542.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035728804.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_035720508.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035724927.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035728858.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_035720940.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035738784.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035733935.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-432720	"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
XP_035721190.1	13	MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969	"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_035728891.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035732223.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-9609523	"HATs acetylate histones";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035718306.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035732774.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_035730105.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035725214.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_035741475.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_035738032.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_035724681.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_035727128.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035737525.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035738610.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_035724966.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_035738827.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway"
XP_035740322.1	31	KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-6799;MetaCyc: PWY-7858;Reactome: R-HSA-163765	"Biotin metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression"
XP_035717250.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035741310.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035731414.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_035728613.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035739127.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035731869.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035732259.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035742853.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035741263.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035721905.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_035731126.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035720680.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035741633.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035737490.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035718579.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035724370.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035738841.1	24	Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-8853659;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;Reactome: R-HSA-4420097;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-422356;Reactome: R-HSA-111931;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-8963896;Reactome: R-HSA-9010642;Reactome: R-HSA-392517;Reactome: R-HSA-164378;Reactome: R-HSA-163560;Reactome: R-HSA-180024;Reactome: R-HSA-9634600;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610783;Reactome: R-HSA-5621575;Reactome: R-HSA-163358	"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"RET signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"VEGFA-VEGFR2 Pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Regulation of insulin secretion";"PKA-mediated phosphorylation of CREB";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"HDL assembly";"ROBO receptors bind AKAP5";"Rap1 signalling";"PKA activation in glucagon signalling";"Triglyceride catabolism";"DARPP-32 events";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"mTOR signaling pathway";"Degradation of GLI2 by the proteasome";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of key metabolic factors"
XP_035731140.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035727493.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_035718472.1	8	KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133	"Tyrosine metabolism";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II"
XP_035743498.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_035732296.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_035729499.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035724415.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_035738333.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_035723204.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035743588.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-113507	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_035728150.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_035723258.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035734373.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035742624.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_035739141.1	11	MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184	"Tunicamycin biosynthesis";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_035743770.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5358346	"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis"
XP_035719981.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_035732755.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_035736744.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_035738217.1	17	MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-200425	"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Carnitine metabolism"
XP_035736602.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"PPARA activates gene expression"
XP_035729777.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_035742439.1	6	MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_035717154.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035732107.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035726909.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-606279	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035722666.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_035723696.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035739574.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_035728971.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035726547.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_035719079.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_035724931.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035740557.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035720287.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035737347.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_035725653.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation"
XP_035736865.1	19	Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970	"Rho GTPase cycle";"Myogenesis";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1"
XP_035737433.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_035739439.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035735650.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035733945.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035719236.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035726913.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase"
XP_035739532.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_035728208.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035726521.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_035741983.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035735109.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15	"Synthesis of PA";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism"
XP_035724094.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035740888.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035720930.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035733468.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035731172.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9620244	"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion homeostasis";"HSF1-dependent transactivation";"Interferon gamma signaling";"Long-term potentiation"
XP_035732451.1	6	Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035718885.1	4	Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14	"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism"
XP_035721317.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740729.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035733127.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035727214.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035738229.1	57	Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113	"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Regulation of RAS by GAPs";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1"
XP_035717497.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035732498.1	16	MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.4;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.4;MetaCyc: PWY-6969;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728	"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"Citrate cycle (TCA cycle)";"Methylaspartate cycle"
XP_035724135.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_035727306.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_035740960.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035743084.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035735896.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex"
XP_035718617.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035733141.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035743259.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035739266.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035717275.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035722146.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035719562.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_035722814.1	39	Reactome: R-HSA-5654228;Reactome: R-HSA-190373;Reactome: R-HSA-5658623;Reactome: R-HSA-5654688;Reactome: R-HSA-5654693;Reactome: R-HSA-2219530;Reactome: R-HSA-5654733;Reactome: R-HSA-5654726;Reactome: R-HSA-190371;Reactome: R-HSA-6811558;Reactome: R-HSA-5654221;Reactome: R-HSA-5654720;Reactome: R-HSA-5654704;Reactome: R-HSA-5654699;Reactome: R-HSA-5654219;Reactome: R-HSA-5654712;Reactome: R-HSA-5654719;Reactome: R-HSA-5655253;Reactome: R-HSA-5654732;Reactome: R-HSA-1839122;Reactome: R-HSA-190322;Reactome: R-HSA-190375;Reactome: R-HSA-8853338;Reactome: R-HSA-1839130;Reactome: R-HSA-190372;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001;Reactome: R-HSA-5654710;Reactome: R-HSA-109704;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-5654687;Reactome: R-HSA-2033519;Reactome: R-HSA-2033514;Reactome: R-HSA-5655302;Reactome: R-HSA-5654227;Reactome: R-HSA-5654727;Reactome: R-HSA-5654689;Reactome: R-HSA-1257604	"Phospholipase C-mediated cascade, FGFR4";"FGFR1c ligand binding and activation";"FGFRL1 modulation of FGFR1 signaling";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR1 signaling";"FGFR3b ligand binding and activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR4";"Signaling by FGFR2 in disease";"Negative regulation of FGFR3 signaling";"Signaling by activated point mutants of FGFR1";"FGFR4 ligand binding and activation";"FGFR2c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"Signaling by activated point mutants of FGFR3";"FGFR3c ligand binding and activation";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR3";"PI3K Cascade";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"Downstream signaling of activated FGFR1";"Activated point mutants of FGFR2";"FGFR3 mutant receptor activation";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade, FGFR3";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR1";"PIP3 activates AKT signaling"
XP_035718846.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035729291.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735490.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035734040.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035719814.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_035740376.1	7	Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-429947	"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA"
XP_035725583.1	5	Reactome: R-HSA-392154;MetaCyc: PWY-4983;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39	"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Arginine and proline metabolism"
XP_035731308.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035741450.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035724043.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_035725493.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035719469.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-174154	"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Regulation of RAS by GAPs";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin"
XP_035737257.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
XP_035732349.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035736730.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism"
XP_035728406.1	9	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-1855204	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol"
XP_035738464.1	26	Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-1362277;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-8866654;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-4615885;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-6804114;Reactome: R-HSA-5655862;Reactome: R-HSA-69183;Reactome: R-HSA-69205;Reactome: R-HSA-174414	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Transcription of E2F targets under negative control by DREAM complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"SUMOylation of DNA replication proteins";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLK";"Processive synthesis on the lagging strand";"G1/S-Specific Transcription";"Processive synthesis on the C-strand of the telomere"
XP_035735675.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035725836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035733574.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035742945.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_035738819.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035727824.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_035744006.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035718062.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035742103.1	9	MetaCyc: PWY-4061;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450"
XP_035742231.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035724488.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_035744281.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035718397.1	3	Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709	"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins"
XP_035739119.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035724598.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035738725.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035735778.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_035742078.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035737113.1	6	Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499	"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane"
XP_035743691.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035735433.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035730553.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_035742986.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_035718210.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035720889.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_035734462.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035729100.1	5	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_035722773.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035743604.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_035743742.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035730709.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035739945.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035742661.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862	"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035743658.1	4	KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerol degradation I"
XP_035739952.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035724711.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_035739103.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035719773.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035737109.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_035727444.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035731987.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035739078.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
XP_035739411.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_035721413.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035725210.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035735088.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035730031.1	14	Reactome: R-HSA-8854518;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5620912;Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Anchoring of the basal body to the plasma membrane";"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_035731375.1	18	KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383	"Methane metabolism";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_035738117.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035741979.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035734548.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7858	"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II"
YP_009915661.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035738614.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_035730278.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_035727629.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700	"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_035723087.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_035717254.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035719382.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035729762.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-187577	"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21"
XP_035735213.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035737922.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035726011.1	16	Reactome: R-HSA-912631;Reactome: R-HSA-194840;Reactome: R-HSA-416476;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6811558;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-1660499	"Regulation of signaling by CBL";"Rho GTPase cycle";"G alpha (q) signalling events";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin receptor SHC signaling";"RET signaling";"Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane"
XP_035742685.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035739817.1	4	Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_035738070.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6282;MetaCyc: PWY-5366;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;MetaCyc: PWY-5989;MetaCyc: PWY-6519;Reactome: R-HSA-75105;MetaCyc: PWY-8049;MetaCyc: PWY-7663;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-7746;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-8047;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-7858	"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Mycobacterial sulfolipid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II"
XP_035722218.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035718836.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035731816.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035730994.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035720684.1	6	Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692	"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity"
XP_035744265.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035719356.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_035719083.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_035743809.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035724374.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035733131.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035722136.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_035730842.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"Removal of the Flap Intermediate";"DNA replication initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_035730855.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035724919.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035728073.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_035717971.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035727787.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
XP_035728108.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_035739685.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035736726.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism"
XP_035725820.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035742935.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035736740.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism"
XP_035725846.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_035729573.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_035731571.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_035735823.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_035720058.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035734067.1	9	MetaCyc: PWY-6118;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-5667	"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I"
XP_035739570.1	6	KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
XP_035742241.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035726743.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling"
XP_035741163.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035743732.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035740947.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035725885.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035722828.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035735443.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035734093.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035738253.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035718128.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035741197.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035732912.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_035732196.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_035723104.1	7	MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-7586	"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_035719828.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_035720934.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035738301.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035721243.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035719050.1	13	MetaCyc: PWY-8052;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204	"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Generation of second messenger molecules";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol"
XP_035732386.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035737943.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_035721790.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035738687.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168333	"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035728997.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736267.1	10	MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;KEGG: 00900+2.3.3.10	"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Butanoate metabolism";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Terpenoid backbone biosynthesis"
XP_035732053.1	10	Reactome: R-HSA-442742;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035724821.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_035742115.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035724427.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035743503.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_035734156.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035727554.1	33	Reactome: R-HSA-69656;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-8939236;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-69202;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-69231	"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin E associated events during G1/S transition";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Cyclin D associated events in G1"
XP_035727940.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035725934.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_035724168.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035729758.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_035737105.1	11	MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"L-glutamine biosynthesis III"
XP_035730608.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035720426.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035727926.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035738960.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035724616.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_035738815.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035731767.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_035720846.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035723670.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_035742507.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035743412.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_035739115.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035743796.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035740578.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)"
XP_035727714.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_035721564.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_035736293.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_035728963.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035735066.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035733673.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_035736637.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035733188.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035735842.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035732270.1	16	Reactome: R-HSA-1251985;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1250342;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-2219530	"Nuclear signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB4 signaling";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_035735901.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_035724211.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035743255.1	58	Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5689901;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895	"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of DVL";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Metalloprotease DUBs";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis"
XP_035717279.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035739731.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035735994.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035734361.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_035728283.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035719465.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand"
XP_035741954.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_035726663.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035741540.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035731730.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035734977.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035724396.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035741526.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_035720062.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035738225.1	17	MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-6722	"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Candicidin biosynthesis"
XP_035726194.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_035728179.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_035724139.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_035720210.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035726101.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035718889.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_035723520.1	29	Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-113418	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex"
XP_035740725.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_035727873.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035718892.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_035724359.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_035738007.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035729879.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_035741038.1	5	MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841	"Folate transformations I";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)"
XP_035718550.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035717183.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035730213.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_035727287.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035730347.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_035737933.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035733880.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_035728024.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_035725889.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism"
XP_035739939.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035736410.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_035717514.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035733445.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035736621.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035717862.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035733703.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_035742312.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035733559.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035727930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035723883.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035741483.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_035736375.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_035722887.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035724837.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035732335.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035726502.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035728877.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_035717754.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_035732707.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_035717708.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_035726409.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035727000.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035733596.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_035722504.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_035728471.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_035740614.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035724431.1	15	MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886	"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)"
XP_035744238.1	5	KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Branched-chain amino acid catabolism"
XP_035740117.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_035736816.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_035735027.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_035723028.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035738402.1	7	MetaCyc: PWY-7782;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;Reactome: R-HSA-1483191	"Plasmalogen biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC"
XP_035734863.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035730580.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377	"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins"
XP_035731740.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035718091.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035720493.1	8	MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_035738947.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;MetaCyc: PWY-5870;MetaCyc: PWY-5872;KEGG: 00130+2.5.1.39	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_035718004.1	7	Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2	"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism"
XP_035731726.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035724915.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035730859.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035738509.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035741530.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035720583.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_035720467.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035741975.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035727967.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_035734491.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035727625.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398	"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway"
XP_035730525.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_035727371.1	5	MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-7817	"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_035731379.1	19	MetaCyc: PWY-7384;MetaCyc: PWY-6969;Reactome: R-HSA-163765;Reactome: R-HSA-71403;Reactome: R-HSA-75105;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism"
XP_035718934.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035742689.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035743274.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035734897.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035743723.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035721794.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035733288.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035729883.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035719054.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_035740343.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035727889.1	11	Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475	"Defective EXT2 causes exostoses 2";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035732170.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035739559.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_035723632.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035726978.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_035740437.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_035720653.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV"
XP_035717179.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035724076.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035739445.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035735302.1	24	Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"RSK activation";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"Integrin signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_035731597.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035739452.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_035722173.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035740831.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_035743707.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-5663;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_035725930.1	42	Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-5617472;Reactome: R-HSA-5625886;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-1912408;Reactome: R-HSA-9610379;Reactome: R-HSA-3214815;Reactome: R-HSA-212300;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-606279;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"DNA methylation";"Packaging Of Telomere Ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"G2/M DNA damage checkpoint";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Pre-NOTCH Transcription and Translation";"HCMV Late Events";"HDACs deacetylate histones";"PRC2 methylates histones and DNA";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Estrogen-dependent gene expression";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression"
XP_035727550.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_035739880.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035726045.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_035724669.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035718873.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_035738125.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035738964.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_035728279.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035731563.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_035737713.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_035742559.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_035739486.1	44	Reactome: R-HSA-5674135;Reactome: R-HSA-202670;Reactome: R-HSA-8940973;Reactome: R-HSA-6802952;Reactome: R-HSA-5663213;Reactome: R-HSA-444257;Reactome: R-HSA-881907;Reactome: R-HSA-445144;Reactome: R-HSA-5675221;Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-2029482;Reactome: R-HSA-112409;Reactome: R-HSA-198753;Reactome: R-HSA-2559582;Reactome: R-HSA-6811558;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.24;Reactome: R-HSA-982772;Reactome: R-HSA-9627069;Reactome: R-HSA-8943724;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-5654732;Reactome: R-HSA-375165;Reactome: R-HSA-9649948;Reactome: R-HSA-9635465;Reactome: R-HSA-450341;Reactome: R-HSA-9634638;Reactome: R-HSA-456926;Reactome: R-HSA-5668599;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-74749;Reactome: R-HSA-162658;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-879415;Reactome: R-HSA-2559580;Reactome: R-HSA-5674499;Reactome: R-HSA-2871796;Reactome: R-HSA-5654727;Reactome: R-HSA-2559585	"MAP2K and MAPK activation";"ERKs are inactivated";"RUNX2 regulates osteoblast differentiation";"Signaling by BRAF and RAF fusions";"RHO GTPases Activate WASPs and WAVEs";"RSK activation";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signal transduction by L1";"Negative regulation of MAPK pathway";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"Regulation of actin dynamics for phagocytic cup formation";"RAF-independent MAPK1/3 activation";"ERK/MAPK targets";"Senescence-Associated Secretory Phenotype (SASP)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Growth hormone receptor signaling";"Regulation of the apoptosome activity";"Regulation of PTEN gene transcription";"ESR-mediated signaling";"Frs2-mediated activation";"Negative regulation of FGFR3 signaling";"NCAM signaling for neurite out-growth";"Signaling downstream of RAS mutants";"Suppression of apoptosis";"Activation of the AP-1 family of transcription factors";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"RHO GTPases Activate NADPH Oxidases";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signal attenuation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Advanced glycosylation endproduct receptor signaling";"Oxidative Stress Induced Senescence";"Negative feedback regulation of MAPK pathway";"FCERI mediated MAPK activation";"Negative regulation of FGFR2 signaling";"Oncogene Induced Senescence"
XP_035719292.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035733312.1	26	Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575	"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling"
XP_035735003.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_035725575.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035720110.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035723177.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035732017.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_035739825.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_035742880.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035734651.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_035736130.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_035717283.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035719289.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035740042.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_035736428.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_035732723.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035726606.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_035722969.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69205;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_035737832.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_035725680.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035740784.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-164944;Reactome: R-HSA-4420097;Reactome: R-HSA-8849471	"Regulation of actin dynamics for phagocytic cup formation";"Nef and signal transduction";"VEGFA-VEGFR2 Pathway";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_035742215.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_035733692.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035738096.1	25	Reactome: R-HSA-8941858;Reactome: R-HSA-9616222;Reactome: R-HSA-8939243;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-8939247;Reactome: R-HSA-8939242;Reactome: R-HSA-8934593;Reactome: R-HSA-8941284;Reactome: R-HSA-8949275;Reactome: R-HSA-9018519;Reactome: R-HSA-8939256;Reactome: R-HSA-8878166;Reactome: R-HSA-8939246;Reactome: R-HSA-8941326;Reactome: R-HSA-8951936;Reactome: R-HSA-8941333;Reactome: R-HSA-8935964;Reactome: R-HSA-8931987;Reactome: R-HSA-8877330;Reactome: R-HSA-8941332;Reactome: R-HSA-8936459;Reactome: R-HSA-8939245;Reactome: R-HSA-8939902;Reactome: R-HSA-8951911	"Regulation of RUNX3 expression and activity";"Transcriptional regulation of granulopoiesis";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates chondrocyte maturation";"RUNX3 Regulates Immune Response and Cell Migration";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates bone development";"RUNX3 regulates p14-ARF";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX2 expression and activity";"RUNX3 regulates RUNX1-mediated transcription"
XP_035741544.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035741950.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035728061.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism"
XP_035731734.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035730257.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035718714.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035733968.1	10	MetaCyc: PWY-5691;Reactome: R-HSA-975634;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171	"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Urate conversion to allantoin II";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions"
XP_035726190.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_035723956.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035717997.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_035728678.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_035737041.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035725625.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035719785.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035720306.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035730364.1	3	Reactome: R-HSA-8955332;Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Carboxyterminal post-translational modifications of tubulin";"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_035722785.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_035736193.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_035744148.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_035736234.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035718554.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035736848.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035718940.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_035734299.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_035738059.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-69231	"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1"
XP_035718508.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035730015.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035739435.1	11	Reactome: R-HSA-5687128;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8943724;Reactome: R-HSA-2871796;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-8862803;Reactome: R-HSA-5617472	"MAPK6/MAPK4 signaling";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN gene transcription";"FCERI mediated MAPK activation";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035718625.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_035735943.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_035743352.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035736414.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_035717510.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035732796.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_035744169.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035718728.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035741797.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_035740074.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_035735105.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_035733949.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035729014.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome"
XP_035740153.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_035727934.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035725940.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035723518.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035726851.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_035742435.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_035737679.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1"
XP_035720228.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035740421.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738322.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035719948.1	16	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-164939;Reactome: R-HSA-8856825;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8856828	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis"
XP_035728085.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035739057.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035721325.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035736140.1	4	KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism"
XP_035727004.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035743174.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_035726457.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035740610.1	11	MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-6538;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5497	"Inosine 5'-phosphate degradation";"Purine metabolism";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)"
XP_035726905.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035727972.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035743386.1	7	MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25	"Phytate degradation I";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system"
XP_035718993.1	14	Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-8055	"Synthesis of PA";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis"
XP_035720472.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035724512.1	11	Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035730494.1	7	MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-31;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922	"Urea cycle";"Arginine biosynthesis";"Putrescine biosynthesis III";"Canavanine degradation";"Urea cycle";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_035721276.1	11	Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery"
XP_035737901.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035730401.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035731602.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035731744.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035722736.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035718000.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035729495.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_035735476.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_035724864.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035743541.1	5	Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007	"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events"
XP_035741534.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035737529.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035728514.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_035739523.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035723879.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035726776.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035741479.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035735870.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035720629.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035737278.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035718930.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_035731865.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035731910.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035725873.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_035728862.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_035744138.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035740217.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035740427.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_035740168.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035717516.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035721386.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035739098.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_035721053.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035733760.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035737212.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035735923.1	17	Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-1834949;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-3270619;Reactome: R-HSA-5693554	"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Cytosolic sensors of pathogen-associated DNA";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRF3-mediated induction of type I IFN";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035719793.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling"
XP_035735511.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
XP_035727362.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035722793.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-203927	"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis"
XP_035736185.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035718652.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_035741518.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_035725920.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035723763.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035738043.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035742835.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035737388.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_035717756.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_035740441.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination"
XP_035738342.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_035739202.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035741655.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_035742051.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035729069.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337	"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding"
XP_035722506.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035736814.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_035744114.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035736469.1	4	Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_035736146.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035729387.1	10	Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Inhibition of membrane repair";"Ub-specific processing proteases"
XP_035737060.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_035733594.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_035724803.1	7	MetaCyc: PWY-6596;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-6798695	"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Inosine 5'-phosphate degradation";"Neutrophil degranulation"
XP_035737037.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035742543.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022702	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands"
XP_035719730.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_035723572.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_035732733.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_035740396.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_035734783.1	14	MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3841	"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"Methane metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)"
XP_035744062.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035731724.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035718006.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035729271.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11	"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis"
XP_035743039.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_035726349.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035717295.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_035726770.1	10	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Ub-specific processing proteases";"Thermogenesis";"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035739543.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035734406.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_035730407.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_035724819.1	9	MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_035732222.1	2	Reactome: R-HSA-9609523;Reactome: R-HSA-3214847	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"HATs acetylate histones"
XP_035728195.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_035743909.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035730942.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035743547.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035718936.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035731916.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035733305.1	26	Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2122947;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-5617472;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-8866907	"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_035730894.1	5	MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;MetaCyc: PWY-6012;MetaCyc: PWY-6289;KEGG: 00770+2.7.8.7	"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Pantothenate and CoA biosynthesis"
XP_035724725.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035731615.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035740323.1	31	MetaCyc: PWY-7858;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-8049;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5366;MetaCyc: PWY-6282;MetaCyc: PWY-5971;MetaCyc: PWY-5973;MetaCyc: PWY-5147	"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Gondoate biosynthesis (anaerobic)";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)"
XP_035742852.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035741262.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035723171.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035732176.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035739425.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035726207.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035728612.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035720765.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_035724505.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_035738033.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_035742845.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_035720668.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand"
XP_035727924.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035720424.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035718738.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035734154.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035737568.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035725936.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-212436	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway"
XP_035727492.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_035720071.1	21	MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7219;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7224	"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_035720992.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_035728900.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_035724614.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_035742425.1	7	MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_035739480.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341	"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors"
XP_035740431.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_035738332.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_035720844.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035741632.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035736136.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035718265.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035743794.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035727716.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_035736218.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_035730699.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700	"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling"
XP_035720989.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_035738152.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035727489.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_035735112.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_035719726.1	4	Reactome: R-HSA-189085;Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_035726600.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins"
XP_035717991.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174184	"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_035724394.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035743049.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035730002.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035726339.1	10	Reactome: R-HSA-5357956;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357905;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"TNFR1-induced NFkappaB signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"Regulation of TNFR1 signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035741524.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035718985.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_035736603.1	14	KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-975634;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4	"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism"
XP_035722726.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_035741956.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035720639.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035726196.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_035735959.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035741982.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035723950.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_035725645.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035730303.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_035726912.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_035739533.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_035721531.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_035725652.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_035719379.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035741999.1	7	MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4	"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Ether lipid metabolism"
XP_035730298.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035730251.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035718920.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035736828.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035720300.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035730932.1	18	MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_035736789.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035728871.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035733886.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035741561.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035722881.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035736416.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_035733764.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035740669.1	6	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis"
XP_035732701.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_035729016.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_035729171.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_035731173.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Interferon gamma signaling";"Ion homeostasis";"HSF1-dependent transactivation";"RAF activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_035720436.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035723567.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035740076.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_035725582.1	5	KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
XP_035727281.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035733845.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_035724042.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_035725492.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035732560.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_035743176.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_035743384.1	7	KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702	"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phytate degradation I"
XP_035738739.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035744110.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_035719563.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_035735047.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035721274.1	11	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035719734.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035742102.1	9	KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-4061	"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione-mediated detoxification I"
XP_035718063.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_035740268.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_035738768.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035737112.1	6	Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66	"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_035717538.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035728756.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_035730496.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035738665.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_035739378.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035731720.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_035736285.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035735474.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_035738927.1	16	Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11	"Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis / Gluconeogenesis"
XP_035721662.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035731746.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_035722734.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_035734891.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035739747.1	15	Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-111465	"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Apoptotic cleavage of cellular proteins"
XP_035739102.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035740735.1	17	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167152;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Th1 and Th2 cell differentiation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035720148.1	13	Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-168638	"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway"
XP_035719772.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035742721.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_035739953.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035721998.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035728516.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_035720893.1	8	Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Photosynthesis";"Oxidative phosphorylation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Ion channel transport"
XP_035732049.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_035729950.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035731785.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_035736220.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_035742378.1	4	MetaCyc: PWY-6906;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210	"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_035735432.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035744214.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035730890.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035735212.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035730423.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035729763.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035719383.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035737511.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_035726259.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035721796.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035732380.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035738370.1	14	Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-1474228;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of the extracellular matrix";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells"
XP_035724447.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035725097.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035727920.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035721412.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035734150.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035736631.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035729622.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035737751.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_035738681.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035739594.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_035728991.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035728072.1	4	Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_035719099.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-400042	"G-protein activation";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_035738966.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035721503.1	10	MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6536;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-5022	"L-glutamate degradation IV";"Butanoate metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation III";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation V"
XP_035732325.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035724827.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241	"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_035728958.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035739484.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_035729797.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_035723069.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035727985.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035720485.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035730198.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035730843.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_035733202.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035743790.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035723038.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035742305.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_035740419.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035718582.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035740786.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035741162.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035721878.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_035723271.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035726604.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation"
XP_035735037.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035738286.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035726658.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035718489.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035724390.1	40	Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73779	"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_035725918.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035718716.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_035727265.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035733917.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035729572.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_035738094.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035741546.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035718599.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035735455.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035734089.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035721242.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035723908.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035724217.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035727635.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling"
XP_035723954.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035718556.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035726515.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035722910.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_035722865.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_035741585.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035743733.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation"
XP_035720304.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035718924.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035730366.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035735442.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035738252.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035734971.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_035729571.1	7	Reactome: R-HSA-8964208;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1	"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylketonuria";"Phenylalanine metabolism"
XP_035735427.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035721005.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035738974.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035732984.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035717485.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035738002.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035718897.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_035720093.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035723272.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035718404.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_035719197.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_035717840.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035718581.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035720067.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035738251.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035734972.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_035735441.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035726968.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_035738298.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035720392.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_035743247.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_035717446.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035741603.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_035738303.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_035721241.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035722163.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035741448.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_035723234.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_035725182.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035735847.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-113507	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_035723193.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035733978.1	10	MetaCyc: PWY-7849;Reactome: R-HSA-975634;MetaCyc: PWY-5691;Reactome: R-HSA-977225;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171	"Urate conversion to allantoin III";"Retinoid metabolism and transport";"Urate conversion to allantoin I";"Amyloid fiber formation";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Non-integrin membrane-ECM interactions"
XP_035736632.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035741136.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_035737864.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_035727806.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035730919.1	4	MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases"
XP_035724855.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035730033.1	14	MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6969	"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_035737786.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_035721411.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035717358.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_035720612.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035717216.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035730186.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_035724842.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035726013.1	16	Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-194840;Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-1257604	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"RET signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Rho GTPase cycle";"G alpha (q) signalling events";"Regulation of signaling by CBL";"PIP3 activates AKT signaling"
XP_035721646.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035726939.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035729410.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035737512.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_035728989.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035731808.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035743626.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035729647.1	11	Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"IRF3-mediated induction of type I IFN"
XP_035737745.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans";"Syndecan interactions"
XP_035739409.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_035719314.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065676;Reactome: R-HSA-3065678	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_035733133.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035741382.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035721788.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035739502.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035720548.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035718320.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035720900.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035737752.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_035738682.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035728071.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_035717973.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035733086.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035736262.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_035728992.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035730145.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_035728116.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_035719206.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_035732672.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_035721661.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035739663.1	10	Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-163680	"Lipophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity"
XP_035735323.1	5	Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035730711.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035734550.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_035725320.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035737111.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_035719065.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035724709.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035743164.1	6	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock"
XP_035744283.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035742233.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_035732839.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035742663.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_035730598.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035738894.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035722771.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035738942.1	12	Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-6978;MetaCyc: PWY-5872;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5857	"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_035720195.1	6	Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6606	"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II"
XP_035743693.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035739697.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_035738407.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035739194.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035740064.1	60	Reactome: R-HSA-77305;MetaCyc: PWY-5136;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77350;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00280+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5138;MetaCyc: PWY-5109;KEGG: 00640+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-7216;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-1361;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;Reactome: R-HSA-77346;MetaCyc: PWY-7779;MetaCyc: PWY-7726;Reactome: R-HSA-77310;KEGG: 00410+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5177;MetaCyc: PWY-7401;MetaCyc: PWY-7778;KEGG: 00310+4.2.1.17;MetaCyc: PWY-6944;Reactome: R-HSA-77288;Reactome: R-HSA-77348	"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Phenylalanine metabolism";"Benzoate degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Caprolactam degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Geraniol degradation";"Fatty acid salvage";"Valine, leucine and isoleucine degradation";"Acyl chain remodeling of CL";"Limonene and pinene degradation";"Butanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fermentation to 2-methylbutanoate";"Propanoate metabolism";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Tryptophan metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoyl-coa degradation I (aerobic)";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"beta-Alanine metabolism";"Tryptophan metabolism";"Butanoate metabolism";"Fatty acid degradation";"Fatty acid elongation";"Fatty acid degradation";"Toluene degradation";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Lysine degradation";"Androstenedione degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA"
XP_035721231.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852	"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy"
XP_035739233.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035719771.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035739101.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035724713.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_035726884.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_035741120.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_035741814.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531	"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus"
XP_035724205.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_035723414.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035722899.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035741469.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_035727256.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
XP_035735915.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035718199.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035732453.1	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035735860.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035721636.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_035724027.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035732147.1	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation"
XP_035732702.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_035743260.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_035722882.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035741562.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035724832.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035727299.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_035736518.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_035740959.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035725897.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism"
XP_035717867.1	13	MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52	"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_035729637.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035731204.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035737735.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_035733143.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035731316.1	4	Reactome: R-HSA-3232142;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664	"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation"
XP_035733905.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035719856.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035723126.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_035724041.1	7	MetaCyc: PWY-5265;MetaCyc: PWY-6470;Reactome: R-HSA-4549356;MetaCyc: PWY-6471;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035725491.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035718336.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035737638.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035729308.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_035728248.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035729354.1	7	Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10	"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_035724874.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035735149.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_035735466.1	10	Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-438066	"Synaptic adhesion-like molecules";"Long-term potentiation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_035727282.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035741236.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035726188.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_035730001.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-983168	"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735669.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035727346.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_035732693.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_035724933.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_035717116.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_035724019.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035717992.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-141430	"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_035728973.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035735111.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I"
XP_035727320.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_035734287.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_035729095.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_035717238.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035742776.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035717844.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035743839.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_035730252.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035728304.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_035717424.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035725698.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_035732164.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035725651.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035718806.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035742329.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_035733697.1	10	KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_035728138.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_035741981.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035735239.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035731348.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035721532.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035737837.1	17	KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-5532;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-5695	"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine salvage";"Purine metabolism";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation"
XP_035730245.1	29	Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-6803207;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;Reactome: R-HSA-6803204;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-5693571;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-69541;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616	"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of Caspase Activators and Caspases";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Nonhomologous End-Joining (NHEJ)";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Sensing of DNA Double Strand Breaks";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Stabilization of p53";"Relaxin signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_035739776.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035717765.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035719106.1	33	Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-4570464	"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"snRNP Assembly";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins"
XP_035737915.1	7	Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism"
XP_035732309.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_035728169.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5685942	"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)"
XP_035735268.1	7	Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-9018681;Reactome: R-HSA-9023661;Reactome: R-HSA-9018676;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695	"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of protectins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation"
XP_035720373.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035739035.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035736014.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035741261.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035726435.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035721468.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_035742851.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035743868.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736	"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis"
XP_035723172.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035731456.1	16	Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035728611.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035719297.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035738423.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_035723308.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035731850.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035738151.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035738198.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035741631.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_035731592.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_035739457.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_035739905.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_035735307.1	24	Reactome: R-HSA-202424;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-2871837;Reactome: R-HSA-354192;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1	"Downstream TCR signaling";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"RSK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"FCERI mediated NF-kB activation";"Integrin signaling";"RHO GTPases activate PKNs";"Relaxin signaling pathway"
XP_035721141.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases"
XP_035739143.1	11	KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_035720958.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_035723134.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_035727458.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035734371.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_035728840.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035720904.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035726673.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_035723637.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035718324.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035725282.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035737149.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_035737466.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035726057.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035734967.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035720991.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_035722310.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035727491.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_035740212.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_035724105.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035721715.1	5	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-917937	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Iron uptake and transport"
XP_035743522.1	33	Reactome: R-HSA-8939236;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-69656;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-69273;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-69202;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Cyclin E associated events during G1/S transition";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_035734508.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035741246.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035718299.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035727156.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035729272.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_035738496.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035743429.1	20	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Relaxin signaling pathway";"Macroautophagy";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035725324.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035744061.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035717248.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035739606.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035732576.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_035724943.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_035723571.1	3	Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271	"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_035738586.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_035718256.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035726215.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_035720782.1	11	Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-1660499;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-5668599;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-1632852	"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system";"Toll Like Receptor 9 (TLR9) Cascade";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Macroautophagy"
XP_035734714.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_035731104.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_035731158.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Long-term potentiation";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity"
XP_035729848.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920	"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability"
XP_035730941.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035732221.1	2	Reactome: R-HSA-9609523;Reactome: R-HSA-3214847	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"HATs acetylate histones"
XP_035728893.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_035742606.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_035730235.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035720516.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_035723240.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035728148.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035735249.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035741965.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_035722643.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035727977.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_035737396.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035735786.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_035740037.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_035727361.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G alpha (q) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035724476.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035737211.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035735512.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_035720044.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035721219.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035718795.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035743264.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035723621.1	14	MetaCyc: PWY-6367;Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-418217;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;Reactome: R-HSA-399997;Reactome: R-HSA-434316;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-500657	"D-myo-inositol-5-phosphate metabolism";"Ca2+ pathway";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G beta:gamma signalling through PLC beta";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Presynaptic function of Kainate receptors"
XP_035726445.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035742133.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035731087.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035732626.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_035740455.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_035739086.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035743137.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035734873.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035731200.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035741792.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035738833.1	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_035735745.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035744279.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257	"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion"
XP_035720295.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035742052.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_035726486.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-174411	"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere"
XP_035718962.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_035726719.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_035741416.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035723144.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035728830.1	4	KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_035733409.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_035721203.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035737139.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035739201.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035740442.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion"
XP_035729350.1	7	KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790	"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II"
XP_035731694.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035728583.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035736048.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035739339.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_035738859.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-1445148	"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035722573.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035731197.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035731601.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035741226.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_035732227.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_035727330.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_035732570.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_035739159.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035737841.1	17	MetaCyc: PWY-5695;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608	"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Pyrimidine metabolism";"Guanosine nucleotides degradation III"
XP_035730402.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035717228.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035724923.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035720750.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-114508	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis"
XP_035734769.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757	"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation"
XP_035724511.1	11	Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862	"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035742196.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035719573.1	7	KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1483226	"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PI"
XP_035742339.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035743618.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_035721429.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035740679.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035737421.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035718250.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035737610.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168333	"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035735578.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_035737827.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035731163.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-442982	"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Long-term potentiation";"Interferon gamma signaling";"Ion homeostasis";"HSF1-dependent transactivation";"RAF activation";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_035724798.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_035728128.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_035723220.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_035743715.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035720510.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_035735229.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035728467.1	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_035740066.1	60	Reactome: R-HSA-77346;MetaCyc: PWY-7779;MetaCyc: PWY-7726;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5177;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7778;MetaCyc: PWY-6944;Reactome: R-HSA-77288;Reactome: R-HSA-77348;MetaCyc: PWY-6945;MetaCyc: PWY-7216;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00380+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-5138;MetaCyc: PWY-5109;KEGG: 00640+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00720+4.2.1.17;MetaCyc: PWY-5136;Reactome: R-HSA-77305;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00360+4.2.1.17;Reactome: R-HSA-77350;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5789;Reactome: R-HSA-77285;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;Reactome: R-HSA-1482798	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Tryptophan metabolism";"Fatty acid degradation";"Fatty acid elongation";"Butanoate metabolism";"Toluene degradation";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Androstenedione degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Tryptophan metabolism";"Benzoyl-coa degradation I (aerobic)";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"Butanoate metabolism";"Butanoate metabolism";"Geraniol degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fermentation to 2-methylbutanoate";"Propanoate metabolism";"Lysine degradation";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to hexanol (engineered)";"Benzoate degradation";"Caprolactam degradation";"Phenylalanine metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Benzoate degradation";"Fatty acid salvage";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Acyl chain remodeling of CL"
XP_035741647.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_035719762.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_035726886.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035737390.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2	"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism"
XP_035744030.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035734265.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_035735780.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_035723416.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_035735803.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_035742368.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis"
XP_035734473.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035721634.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_035725783.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035740855.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_035729399.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035717629.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035722762.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_035736593.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035720471.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035740278.1	52	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_035729218.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035717787.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035738778.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035718108.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035741375.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_035718154.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035727367.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035735725.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035734738.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035739080.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_035729356.1	7	Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I"
XP_035737217.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035732685.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035722995.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_035735464.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035724876.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_035726480.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035723124.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_035719854.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035718334.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035726852.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035738321.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035740422.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035737437.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_035728062.1	18	KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7416	"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_035723666.1	13	Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"mTOR signalling"
XP_035739349.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_035741230.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035720283.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035725657.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_035732986.1	19	MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;Reactome: R-HSA-380320;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6	"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism"
XP_035734936.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035743532.1	5	Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-171007	"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"p38MAPK events"
XP_035718406.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813	"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids"
XP_035729438.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607761	"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_035737831.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_035729773.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_035731771.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035722659.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035738213.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_035718800.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035724064.1	7	Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351	"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_035717444.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035729224.1	14	MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4	"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Ether lipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism"
XP_035730007.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition"
XP_035742349.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035738360.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035738088.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_035737042.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035728210.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_035723236.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035728363.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035733515.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_035744195.1	11	KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-5381;MetaCyc: PWY-6608;MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-6606;MetaCyc: PWY-7821;MetaCyc: PWY-5695;KEGG: 00230+3.1.3.5	"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"Purine metabolism"
XP_035730225.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035731899.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035738157.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035738608.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_035735394.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108	"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_035739498.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035727858.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035739451.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_035735301.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035741637.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035740832.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_035728885.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035726098.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035722875.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035734377.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054	"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway"
XP_035727497.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_035717214.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035730687.1	34	Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9639288;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168333	"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Amino acids regulate mTORC1";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035738705.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035741308.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035729814.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_035733296.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_035734748.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035740041.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_035729120.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_035743624.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_035742451.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035721868.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_035730729.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-350562	"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)"
XP_035728820.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_035733311.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-5617472	"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Circadian Clock";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035733084.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035728114.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_035727275.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035724959.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_035730815.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035737460.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035741244.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035739755.1	6	KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_035727154.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035722777.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035731690.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035720605.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035743103.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035727657.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_035718092.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_035743078.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035734924.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035734165.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_035738401.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_035732574.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035718089.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035731983.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_035738584.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_035719777.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035736479.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035725326.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035717836.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035721237.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035739604.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_035731106.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_035739515.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_035740178.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035734599.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_035719348.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035717430.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
XP_035730717.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035725779.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035734582.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_035728629.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035718393.1	3	Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985	"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose"
XP_035737117.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_035742691.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035742107.1	9	KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061	"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I"
XP_035723224.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_035720514.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035725858.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_035728434.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035726760.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis"
XP_035730023.1	12	KEGG: 00670+2.1.2.9;Reactome: R-HSA-196780;MetaCyc: PWY-6277;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;KEGG: 00970+2.1.2.9;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2	"One carbon pool by folate";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"One carbon pool by folate"
XP_035724474.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035735784.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_035731633.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination"
XP_035725497.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_035743266.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035739259.1	10	KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_035737253.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_035717128.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035723185.1	5	Reactome: R-HSA-977347;KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95	"Serine biosynthesis";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_035733498.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035721630.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035725587.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035720046.1	19	Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038	"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"VLDL assembly";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"VLDL clearance";"Chylomicron clearance";"Post-translational protein phosphorylation";"LDL clearance"
XP_035717493.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035721260.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_035722482.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_035739084.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_035718150.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_035744072.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"HDMs demethylate histones"
XP_035721313.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035724539.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035741869.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035729261.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_035731263.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_035724021.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035735129.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035726501.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035718330.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_035738257.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_035734097.1	24	Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861	"Recycling pathway of L1";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly"
XP_035735447.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8	"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism"
XP_035725609.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035726378.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035718463.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_035729285.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035723448.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035733159.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035724212.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035742774.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035717846.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035732829.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035725330.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035718804.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035719338.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035729577.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035733912.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035732555.1	4	KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_035729220.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_035724060.1	5	KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4	"Geraniol degradation";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies"
XP_035722607.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035720775.1	4	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation elongation"
XP_035725613.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035738364.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035732166.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035732449.1	6	Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035729246.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_035728306.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_035726102.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035723828.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035741428.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035734063.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_035741664.1	4	MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26	"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_035739223.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035720678.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035737229.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_035742732.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-445144	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Signal transduction by L1"
XP_035739774.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035724388.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_035722338.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_035723619.1	14	Reactome: R-HSA-4086398;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-418217;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;Reactome: R-HSA-399997;MetaCyc: PWY-8052;Reactome: R-HSA-434316;MetaCyc: PWY-6351;Reactome: R-HSA-500657	"Ca2+ pathway";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G beta:gamma signalling through PLC beta";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"2-arachidonoylglycerol biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Presynaptic function of Kainate receptors"
XP_035719087.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_035736016.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035741130.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114	"G0 and Early G1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_035722369.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035743685.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035727800.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_035729792.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_035732219.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035733025.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035727783.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035729789.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_035742813.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_035717210.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_035724037.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_035731454.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035739809.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_035725367.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035721417.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_035743620.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis"
XP_035724907.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035718340.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035743411.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_035723218.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035723136.1	18	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-975957	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035724549.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035735217.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035737464.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035737628.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035729309.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035728249.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035743354.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035733882.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_035735148.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035727303.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_035737639.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035742475.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_035743134.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035740958.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035723453.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035736519.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035742263.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035727932.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035727298.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_035717860.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_035742310.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035742297.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035740373.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035724020.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035723121.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035729313.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_035722905.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035738324.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_035718331.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035743267.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_035725496.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035718198.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035721261.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239	"Cilium Assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1"
XP_035741468.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_035722143.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035720474.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035737269.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035727974.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035741127.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114	"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_035719905.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_035719457.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-2206291;Reactome: R-HSA-2024096	"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation"
XP_035726075.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_035727002.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035722898.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035718843.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035738400.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_035742106.1	4	MetaCyc: PWY-6906;MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_035721079.1	179	Reactome: R-HSA-69541;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-975144;Reactome: R-HSA-2979096;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-1236382;Reactome: R-HSA-180534;Reactome: R-HSA-1295596;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-901032;Reactome: R-HSA-2559585;Reactome: R-HSA-3134975;Reactome: R-HSA-201681;Reactome: R-HSA-9014325;Reactome: R-HSA-2122947;Reactome: R-HSA-168638;Reactome: R-HSA-211733;Reactome: R-HSA-8948747;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-174113;Reactome: R-HSA-8863795;Reactome: R-HSA-6791226;Reactome: R-HSA-8875360;Reactome: R-HSA-6783310;Reactome: R-HSA-174048;Reactome: R-HSA-5655862;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-8849469;Reactome: R-HSA-5654727;Reactome: R-HSA-937039;Reactome: R-HSA-5607761;Reactome: R-HSA-5693607;Reactome: R-HSA-195253;Reactome: R-HSA-5696395;Reactome: R-HSA-2173791;Reactome: R-HSA-450302;Reactome: R-HSA-4641258;Reactome: R-HSA-2894862;Reactome: R-HSA-6782210;Reactome: R-HSA-5654732;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-977225;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5654726;Reactome: R-HSA-156902;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-6781827;Reactome: R-HSA-937041;Reactome: R-HSA-8876493;Reactome: R-HSA-5696394;Reactome: R-HSA-975956;Reactome: R-HSA-2173788;Reactome: R-HSA-9033241;Reactome: R-HSA-5656169;Reactome: R-HSA-6804760;Reactome: R-HSA-5689880;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-1253288;Reactome: R-HSA-72706;Reactome: R-HSA-68949;Reactome: R-HSA-5689896;Reactome: R-HSA-2173795;Reactome: R-HSA-205043;Reactome: R-HSA-5362768;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-9646399;Reactome: R-HSA-4608870;Reactome: R-HSA-3322077;Reactome: R-HSA-168927;Reactome: R-HSA-6782135;Reactome: R-HSA-5654733;Reactome: R-HSA-72764;Reactome: R-HSA-2467813;Reactome: R-HSA-400253;Reactome: R-HSA-3769402;Reactome: R-HSA-9615710;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-8951664;Reactome: R-HSA-8866652;Reactome: R-HSA-2672351;Reactome: R-HSA-9613829;Reactome: R-HSA-5610783;Reactome: R-HSA-5696397;Reactome: R-HSA-168928;Reactome: R-HSA-2559580;Reactome: R-HSA-1236974;Reactome: R-HSA-5675482;Reactome: R-HSA-174154;Reactome: R-HSA-2644606;Reactome: R-HSA-6807004;Reactome: R-HSA-2565942;Reactome: R-HSA-3785653;Reactome: R-HSA-5689901;Reactome: R-HSA-175474;Reactome: R-HSA-110314;Reactome: R-HSA-5684264;Reactome: R-HSA-69017;Reactome: R-HSA-5693565;Reactome: R-HSA-5358346;Reactome: R-HSA-917937;Reactome: R-HSA-5357905;Reactome: R-HSA-2691232;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-174490;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-6804756;Reactome: R-HSA-937072;Reactome: R-HSA-192823;Reactome: R-HSA-9636383;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-917729;Reactome: R-HSA-156827;Reactome: R-HSA-9645460;Reactome: R-HSA-4641257;Reactome: R-HSA-936964;Reactome: R-HSA-975957;Reactome: R-HSA-9013973;Reactome: R-HSA-110312;Reactome: R-HSA-6804757;Reactome: R-HSA-5696400;Reactome: R-HSA-5675221;Reactome: R-HSA-5632684;Reactome: R-HSA-5656121;Reactome: R-HSA-936440;Reactome: R-HSA-2173796;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-9637628;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-6781823;Reactome: R-HSA-8856828;Reactome: R-HSA-5676590;Reactome: R-HSA-9013507;Reactome: R-HSA-69231;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-2122948;Reactome: R-HSA-1169408;Reactome: R-HSA-1358803;Reactome: R-HSA-72689;Reactome: R-HSA-5689603;Reactome: R-HSA-8866654;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-4641263;Reactome: R-HSA-5689877;Reactome: R-HSA-975163;Reactome: R-HSA-8856825;Reactome: R-HSA-912631;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-532668;Reactome: R-HSA-202424;Reactome: R-HSA-162588	"Stabilization of p53";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Vpu mediated degradation of CD4";"Spry regulation of FGF signaling";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"ER Quality Control Compartment (ERQC)";"Oncogene Induced Senescence";"Regulation of innate immune responses to cytosolic DNA";"TCF dependent signaling in response to WNT";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOTCH1 Intracellular Domain Regulates Transcription";"NOD1/2 Signaling Pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN localization";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downregulation of ERBB2 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"InlB-mediated entry of Listeria monocytogenes into host cell";"Fanconi Anemia Pathway";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion synthesis by POLK";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Negative regulation of FGFR2 signaling";"IRAK1 recruits IKK complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Processing of DNA double-strand break ends";"Degradation of beta-catenin by the destruction complex";"Formation of Incision Complex in GG-NER";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"activated TAK1 mediates p38 MAPK activation";"Degradation of DVL";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Negative regulation of FGFR3 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Amyloid fiber formation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR1 signaling";"Peptide chain elongation";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"IKK complex recruitment mediated by RIP1";"InlA-mediated entry of Listeria monocytogenes into host cells";"DNA Damage Recognition in GG-NER";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Downregulation of TGF-beta receptor signaling";"Peroxisomal protein import";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Methylation";"Ub-specific processing proteases";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downregulation of ERBB4 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Orc1 removal from chromatin";"Ovarian tumor domain proteases";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"NRIF signals cell death from the nucleus";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Aggrephagy";"Asymmetric localization of PCP proteins";"Glycogen synthesis";"TICAM1, RIP1-mediated IKK complex recruitment";"Dual incision in TC-NER";"Negative regulation of FGFR4 signaling";"Eukaryotic Translation Termination";"Separation of Sister Chromatids";"Circadian Clock";"Deactivation of the beta-catenin transactivating complex";"Late endosomal microautophagy";"EGFR downregulation";"Selenocysteine synthesis";"Neddylation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Stimuli-sensing channels";"Chaperone Mediated Autophagy";"Degradation of GLI2 by the proteasome";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Oxidative Stress Induced Senescence";"ER-Phagosome pathway";"Regulation of necroptotic cell death";"APC/C:Cdc20 mediated degradation of Securin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of MET activity";"Regulation of PLK1 Activity at G2/M Transition";"Myoclonic epilepsy of Lafora";"Metalloprotease DUBs";"Assembly Of The HIV Virion";"Recognition of DNA damage by PCNA-containing replication complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CDK-mediated phosphorylation and removal of Cdc6";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Hedgehog ligand biogenesis";"Iron uptake and transport";"Regulation of TNFR1 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Membrane binding and targetting of GAG proteins";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"Regulation of TP53 Activity through Phosphorylation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Viral mRNA Translation";"Prevention of phagosomal-lysosomal fusion";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Alpha-protein kinase 1 signaling pathway";"Degradation of AXIN";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TICAM1-dependent activation of IRF3/IRF7";"Translesion synthesis by REV1";"Regulation of TP53 Degradation";"Dual Incision in GG-NER";"Negative regulation of MAPK pathway";"Hedgehog 'on' state";"Translesion synthesis by POLI";"Negative regulators of DDX58/IFIH1 signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Modulation by Mtb of host immune system";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Formation of TC-NER Pre-Incision Complex";"Clathrin-mediated endocytosis";"NIK-->noncanonical NF-kB signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Activated NOTCH1 Transmits Signal to the Nucleus";"ISG15 antiviral mechanism";"Downregulation of ERBB2:ERBB3 signaling";"Formation of a pool of free 40S subunits";"UCH proteinases";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of FZD by ubiquitination";"Josephin domain DUBs";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of signaling by CBL";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downstream TCR signaling";"Budding and maturation of HIV virion"
XP_035730492.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035743987.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_035724514.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-205043	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus"
XP_035728745.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035730716.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition"
XP_035725833.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_035741532.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035730599.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035731742.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035731604.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035744003.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035731107.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_035717837.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035732838.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035725327.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035742690.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035739106.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_035719776.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035734888.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035728512.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_035721118.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_035738806.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035724605.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035735436.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035727656.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_035733771.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_035722776.1	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_035730924.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_035735216.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035723634.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035723137.1	18	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_035719052.1	13	KEGG: 04070+3.1.4.11;Reactome: R-HSA-202433;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"Generation of second messenger molecules";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_035717211.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_035721792.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035734125.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035726054.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035722045.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035721789.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035722052.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_035729640.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035741131.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA"
XP_035739454.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_035731809.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035728988.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035725366.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035739408.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_035741203.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_035742643.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035726938.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035719133.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035718341.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035724036.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035721627.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035728111.1	7	Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;MetaCyc: PWY-7980	"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Mitochondrial protein import";"Cristae formation";"ATP biosynthesis"
XP_035743410.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_035738962.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035729811.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis"
XP_035730918.1	4	MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases"
XP_035728669.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_035743375.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035736017.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035742454.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035723264.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs"
XP_035743621.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_035732350.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035742408.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035726720.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_035721285.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035741555.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035740782.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035725331.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035741166.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035741449.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation"
XP_035737834.1	7	Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_035729247.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_035717427.1	5	Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
XP_035732167.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738299.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035736274.1	18	KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643	"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"Arginine biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II"
XP_035731732.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035722606.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_035732664.1	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_035720060.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035718712.1	12	Reactome: R-HSA-73776;Reactome: R-HSA-2029482;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-5663213;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Regulation of actin dynamics for phagocytic cup formation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate WASPs and WAVEs";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_035725198.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis"
XP_035725843.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_035733694.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035729576.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_035724775.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035733197.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035741542.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035725423.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_035744105.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_035717847.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035718545.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035718552.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035731774.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862	"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035736232.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035724061.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035729221.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_035728268.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035718890.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_035735446.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035735169.1	1	Reactome: R-HSA-419771	"Opsins"
XP_035734096.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035728022.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_035717512.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035733454.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035730635.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035737138.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035732375.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035737216.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035729357.1	7	Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I"
XP_035727366.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035728431.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035726615.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_035717786.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035718656.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035724471.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035744278.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054	"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA"
XP_035725942.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035737391.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_035742314.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035744031.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035717864.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735781.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism"
XP_035721136.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035724024.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035731080.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035721218.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035726504.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035740612.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035727970.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_035720470.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035741646.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_035729672.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035739081.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035740067.1	60	KEGG: 00640+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00650+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-7094;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5789;Reactome: R-HSA-77285;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00280+4.2.1.17;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00360+4.2.1.17;Reactome: R-HSA-77305;MetaCyc: PWY-5136;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7778;MetaCyc: PWY-7656;MetaCyc: PWY-5177;Reactome: R-HSA-77288;Reactome: R-HSA-77348;MetaCyc: PWY-6944;MetaCyc: PWY-7726;MetaCyc: PWY-7779;Reactome: R-HSA-77346;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00410+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6583;MetaCyc: PWY-6945;MetaCyc: PWY-7606;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7007	"Propanoate metabolism";"Fermentation to 2-methylbutanoate";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"Geraniol degradation";"Butanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Limonene and pinene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid salvage";"Geraniol degradation";"alpha-Linolenic acid metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Benzoate degradation";"Acyl chain remodeling of CL";"Valine, leucine and isoleucine degradation";"Benzoate degradation";"Caprolactam degradation";"Phenylalanine metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Androstenedione degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl tert-butyl ether degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid elongation";"Fatty acid degradation";"Butanoate metabolism";"Fatty acid degradation";"Toluene degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"beta-Alanine metabolism";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Tryptophan metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)"
XP_035718319.1	5	MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)"
XP_035732571.1	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
XP_035738404.1	7	MetaCyc: PWY-7886;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-7782;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism"
XP_035735248.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_035737840.1	17	KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-7179;MetaCyc: PWY-6620;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6644	"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine salvage";"Purine metabolism";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis"
XP_035731339.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035720751.1	13	Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763	"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation"
XP_035721603.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035737826.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035724510.1	11	Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862	"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035737595.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035742163.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_035731159.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Ion homeostasis";"Interferon gamma signaling";"Long-term potentiation";"Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions"
XP_035734513.1	5	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates"
XP_035731600.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035734921.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035742197.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035738863.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_035721619.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091	"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of DVL";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells"
XP_035743428.1	12	Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1	"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway"
XP_035718303.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035743167.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_035717249.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035732226.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_035718298.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_035740093.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035734509.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035739163.1	6	KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-913709	"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins"
XP_035728915.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_035731196.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035718932.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035737420.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035734753.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035730920.1	4	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437	"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation"
XP_035718251.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035739899.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_035727459.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035741266.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035734960.1	26	Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion"
XP_035737148.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_035731588.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035738199.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035733633.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035727890.1	11	Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475	"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035717268.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035724963.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_035735300.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035739450.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_035725932.1	29	Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-113418	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex"
XP_035727552.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035733297.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_035723309.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035733310.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-9018519;Reactome: R-HSA-918233;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Estrogen-dependent gene expression";"TRAF3-dependent IRF activation pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035732293.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_035728821.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035743414.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_035730686.1	34	Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9639288;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142	"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Amino acids regulate mTORC1";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins"
XP_035725319.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434	"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035727496.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_035734376.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_035721469.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035721146.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035737461.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035729868.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236974	"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Degradation of DVL";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway"
XP_035719290.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_035744027.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035741636.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035738565.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035729121.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_035727712.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_035732308.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035742450.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035735269.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035738156.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035742882.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035721562.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035722663.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_035741945.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035723237.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035725682.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035728139.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state"
XP_035740195.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035731349.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035735238.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035737830.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035742328.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_035720064.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035730006.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_035741231.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_035726465.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3371453	"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response"
XP_035721438.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_035719663.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-901032;MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_035743838.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_035725699.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_035741103.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035735989.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035743095.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_035728211.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_035741986.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035724018.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035726192.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_035727327.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035726916.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035735765.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035731770.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;MetaCyc: PWY-7511	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination"
XP_035726189.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_035734937.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035718801.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035725656.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_035735668.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035718894.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_035723667.1	13	Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-166208	"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Macroautophagy";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"mTORC1-mediated signalling"
XP_035738361.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035742850.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035741260.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035724958.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_035726056.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035737467.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035719259.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_035723636.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035733875.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035735214.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035724991.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035717253.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035741313.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035735306.1	24	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"Thermogenesis";"Human immunodeficiency virus 1 infection";"RSK activation";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway";"Integrin signaling";"RHO GTPases activate PKNs";"Activation of AKT2";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection"
XP_035721869.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_035739456.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_035738613.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_035730728.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035721414.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway"
XP_035734749.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035742499.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_035721140.1	10	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_035719296.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035741309.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035726099.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035728074.1	4	Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_035739592.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_035731457.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation"
XP_035733316.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035727490.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_035722311.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035733258.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_035724373.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035738150.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035730993.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035738609.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_035720683.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569	"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"HCMV Early Events";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_035728447.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035739499.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_035719107.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142	"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins"
XP_035726602.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_035739777.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035741164.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035741925.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035735110.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051	"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I"
XP_035731329.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035717505.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035733696.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035742348.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035734931.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035718807.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035719755.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035730000.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035725113.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035720933.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035721244.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035741980.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035723952.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035726910.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035729439.1	11	MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782	"Anandamide biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Sphingolipid metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis"
XP_035723103.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035723078.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_035718922.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035733100.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035720302.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035738254.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035730930.1	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7187;Reactome: R-HSA-499943	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates"
XP_035735444.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035725109.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035723945.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_035725650.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035741237.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1236974	"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Regulation of RAS by GAPs";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway"
XP_035717803.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis"
XP_035733762.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035735818.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035743083.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035719809.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_035727088.1	12	Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TNF signaling";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation"
XP_035723620.1	14	Reactome: R-HSA-1855204;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-418217;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;MetaCyc: PWY-6351;Reactome: R-HSA-434316;MetaCyc: PWY-8052;Reactome: R-HSA-399997;Reactome: R-HSA-112043	"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"G beta:gamma signalling through PLC beta";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"2-arachidonoylglycerol biosynthesis";"Acetylcholine regulates insulin secretion";"PLC beta mediated events"
XP_035726487.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035735629.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035742200.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035738779.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035718109.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_035729219.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035727213.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035734739.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035727360.1	24	Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-420092	"G alpha (q) signalling events";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors"
XP_035743136.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035739087.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_035740279.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_035728055.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_035731086.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035732810.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_035725494.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035717628.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035732965.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035736560.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035723685.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035725584.1	5	MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Arginine biosynthesis"
XP_035733995.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035739200.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035719813.1	6	Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6	"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism"
XP_035729351.1	7	KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790	"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II"
XP_035731353.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035724477.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035740036.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_035722813.1	39	Reactome: R-HSA-5654228;Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-5654693;Reactome: R-HSA-5654688;Reactome: R-HSA-5658623;Reactome: R-HSA-2219530;Reactome: R-HSA-190373;Reactome: R-HSA-190371;Reactome: R-HSA-6811558;Reactome: R-HSA-5654221;Reactome: R-HSA-5654219;Reactome: R-HSA-5654699;Reactome: R-HSA-5654712;Reactome: R-HSA-5654704;Reactome: R-HSA-5654720;Reactome: R-HSA-5654732;Reactome: R-HSA-5655253;Reactome: R-HSA-5654719;Reactome: R-HSA-190322;Reactome: R-HSA-1839122;Reactome: R-HSA-5654706;Reactome: R-HSA-190372;Reactome: R-HSA-1839130;Reactome: R-HSA-190375;Reactome: R-HSA-8853338;Reactome: R-HSA-5673001;Reactome: R-HSA-5654695;Reactome: R-HSA-5654710;Reactome: R-HSA-109704;Reactome: R-HSA-2033519;Reactome: R-HSA-2033514;Reactome: R-HSA-5654687;Reactome: R-HSA-5654700;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-1257604;Reactome: R-HSA-5654727;Reactome: R-HSA-5654689	"Phospholipase C-mediated cascade, FGFR4";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR1";"FGFRL1 modulation of FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFR1c ligand binding and activation";"FGFR3b ligand binding and activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2";"Phospholipase C-mediated cascade: FGFR1";"SHC-mediated cascade:FGFR2";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR4";"Negative regulation of FGFR3 signaling";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR4";"FGFR4 ligand binding and activation";"Signaling by activated point mutants of FGFR1";"FRS-mediated FGFR3 signaling";"FGFR3c ligand binding and activation";"Signaling by activated point mutants of FGFR3";"FGFR2c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR2";"PI-3K cascade:FGFR3";"PI3K Cascade";"Activated point mutants of FGFR2";"FGFR3 mutant receptor activation";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR2 signaling";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"PIP3 activates AKT signaling";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR1"
XP_035744037.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_035731201.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035735787.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_035727209.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035737114.1	6	Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66	"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_035744060.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035735228.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035720517.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_035742607.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035735579.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_035740775.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-8849471;Reactome: R-HSA-2029482;Reactome: R-HSA-164944	"VEGFA-VEGFR2 Pathway";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of actin dynamics for phagocytic cup formation";"Nef and signal transduction"
XP_035742104.1	9	KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061	"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I"
XP_035723570.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122	"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035719732.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035721428.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035727823.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
XP_035731606.1	17	Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-8951664;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-69017	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Neddylation";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6"
XP_035740678.1	6	Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035733573.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035723005.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_035718257.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035730714.1	14	MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-561	"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_035743619.1	4	MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_035738587.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_035724756.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035732220.1	2	Reactome: R-HSA-9609523;Reactome: R-HSA-3214847	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"HATs acetylate histones"
XP_035732577.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035739607.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035727443.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035723241.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035720943.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035729449.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035717229.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035719774.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035738497.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035744212.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035743603.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_035720105.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035722774.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_035741247.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035739338.1	3	KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
XP_035734665.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035730940.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035735434.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035738858.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_035719207.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_035724548.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035741264.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035742854.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035733087.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035737629.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035742808.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_035728614.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035729411.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035734145.1	4	Reactome: R-HSA-189483;MetaCyc: PWY-5874;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18	"Heme degradation";"Heme degradation I";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism"
XP_035718433.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035725360.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_035727922.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035723131.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis"
XP_035734374.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035739808.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035721647.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_035720901.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035723203.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035743789.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035732218.1	2	Reactome: R-HSA-9609523;Reactome: R-HSA-3214847	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"HATs acetylate histones"
XP_035730187.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035728070.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_035730684.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035741357.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035729788.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_035727494.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_035743792.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035722368.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035718778.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035738154.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035725976.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735397.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035727807.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035741634.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035728505.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035722339.1	9	Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-2871809	"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization"
XP_035739573.1	6	KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_035735846.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_035723618.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_035726726.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035732603.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_035735617.1	6	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_035718580.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_035717841.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035717153.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035737228.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_035720679.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035729570.1	7	KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-7158	"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V"
XP_035729227.1	14	MetaCyc: PWY-8052;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969	"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Synthesis of PC";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Triglyceride biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina"
XP_035717447.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035732448.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035736743.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_035724392.1	9	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-9656255	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Defective OGG1 Substrate Binding"
XP_035730058.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035725823.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035719339.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035741522.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035718859.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_035720066.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035721240.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_035741984.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035724093.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035719196.1	20	Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends"
XP_035726914.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035727015.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes"
XP_035729935.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035732828.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035741849.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710	"SUMOylation of transcription cofactors";"Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy"
XP_035723166.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035723449.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_035718896.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_035728301.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_035717421.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035735440.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035737434.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_035738250.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035725654.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events"
XP_035735467.1	10	Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Long-term potentiation";"Synaptic adhesion-like molecules";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_035737214.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035742291.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035735128.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962	"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex"
XP_035722498.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_035718337.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035743261.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_035740963.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035724538.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035725525.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_035723127.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_035731317.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8934593	"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity"
XP_035741121.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_035729636.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035721267.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035718608.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035727364.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035717784.1	13	Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_035718654.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_035719498.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-211733	"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of DVL";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_035724040.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_035721293.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_035739258.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13	"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism"
XP_035724026.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035717129.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035721637.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_035738344.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_035739204.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035735493.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035741644.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_035733592.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_035720205.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035741147.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_035735583.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-8854050	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_035721308.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_035737110.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035725321.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_035737824.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035728819.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_035728628.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_035725675.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035720713.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_035739696.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_035742100.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_035718209.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035719349.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035721660.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035734598.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035729119.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_035727113.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12	"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_035730710.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035731722.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035734551.1	5	KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88	"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism"
XP_035740179.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035734488.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035724195.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035736733.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8934593	"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity"
XP_035743666.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035732773.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_035729945.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035732224.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_035718088.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035721230.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035739100.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_035719770.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035730889.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035728803.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035743079.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035721987.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035729103.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035736222.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_035729952.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035737963.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035731721.1	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_035729274.1	10	KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11	"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Methane metabolism"
XP_035740214.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_035741049.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_035743524.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-4420097	"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"p38MAPK events";"DSCAM interactions";"VEGFA-VEGFR2 Pathway"
XP_035734890.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035742688.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035734459.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035724148.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_035731378.1	19	KEGG: 00640+6.2.1.5;MetaCyc: PWY-5172;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-6969;Reactome: R-HSA-163765;MetaCyc: PWY-7384	"Propanoate metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_035728517.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_035725322.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730275.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_035717832.1	13	KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_035731102.1	9	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68689	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex"
XP_035738940.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;MetaCyc: PWY-5872	"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_035730858.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035736221.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_035729951.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035718059.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7227	"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_035720866.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Regulation of RAS by GAPs";"Degradation of DVL";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_035733395.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_035742969.1	11	MetaCyc: PWY-7356;Reactome: R-HSA-532668;Reactome: R-HSA-196819;MetaCyc: PWY-6907;Reactome: R-HSA-901042;MetaCyc: PWY-6908;Reactome: R-HSA-381426;KEGG: 00730+2.7.6.2;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;MetaCyc: PWY-6898	"Thiamine salvage IV (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Calnexin/calreticulin cycle";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Thiamine metabolism";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Thiamine salvage III"
XP_035741537.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035719215.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035738926.1	16	MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-6901;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-1622	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)"
XP_035724867.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_035743999.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035730497.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035734586.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_035723029.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035728757.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_035728943.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735046.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035720055.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035732883.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035727007.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035738873.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035744239.1	5	Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4	"Branched-chain amino acid catabolism";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation"
XP_035726408.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035722703.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_035726454.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035743177.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_035730779.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035719703.1	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035743262.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035728870.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035722880.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035726643.1	10	KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism"
XP_035741560.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035742938.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035717709.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_035737179.1	3	Reactome: R-HSA-8950505;Reactome: R-HSA-3214847;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"HATs acetylate histones";"Methionine salvage pathway"
XP_035739054.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035732700.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_035735514.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)"
XP_035732561.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_035737283.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035741794.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035733558.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035735605.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035733504.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_035723566.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035720343.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035729017.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_035733591.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_035739938.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035722825.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_035727280.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035718125.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035736417.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_035719719.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035717713.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035724391.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035741913.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_035738000.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035741039.1	5	MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20	"Folate transformations I";"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes"
XP_035730367.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035726983.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035736693.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_035719188.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_035743879.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035729878.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_035733273.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035732585.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Neddylation"
XP_035718888.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_035737877.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035717842.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035738575.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6804756	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation"
XP_035728178.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_035735906.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035721572.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035735279.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035717994.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174184	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_035724138.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-983231	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production"
XP_035733192.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035720390.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035741547.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035733916.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035731305.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_035718717.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_035730254.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035732162.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035728302.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_035717422.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035734970.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035731737.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035729255.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035738287.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035717278.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035742736.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-445144	"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Signal transduction by L1"
XP_035736667.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035732546.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035724973.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035721534.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035728933.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035727921.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035738728.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035736630.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035724595.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035742075.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035729796.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_035730613.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035729412.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035724826.1	9	MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-6142	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_035737510.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_035736309.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_035735678.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035723174.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035742500.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_035721622.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_035724840.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035742948.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Signaling by Hippo";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035720447.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-5789	"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_035731594.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035728683.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_035730609.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035743791.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035726310.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692	"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation"
XP_035729503.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_035724446.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_035724169.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035720333.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035741380.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035738680.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035723132.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_035740434.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_035743655.1	4	Reactome: R-HSA-5661270;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Glycerol degradation I";"Glycerolipid metabolism";"Pentose and glucuronate interconversions"
XP_035725284.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035739948.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035717679.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_035720902.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035731917.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035729270.1	10	Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis";"Methane metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_035734942.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035735471.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035744139.1	4	MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603	"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine"
XP_035740210.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_035739273.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035741478.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_035723878.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035730406.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035727125.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035719731.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035737279.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035734955.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_035731543.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035743495.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_035738944.1	12	KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_035738892.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035718007.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035723255.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035729386.1	10	Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Negative regulation of MET activity";"Inhibition of membrane repair"
XP_035736147.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035740846.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_035729053.1	11	Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_035725921.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035719884.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035722507.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_035740617.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035724834.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035724248.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_035741564.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035733761.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035723519.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035736453.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_035732758.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway"
XP_035735510.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202	"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition"
XP_035717757.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_035732704.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_035730175.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035731202.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035733948.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035721069.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035729345.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_035740885.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035737061.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_035723503.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035727284.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035744168.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035729352.1	7	KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10	"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes"
XP_035742050.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035717517.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035721387.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035718960.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism"
XP_035736868.1	19	Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-983231	"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"Rho GTPase cycle";"Myogenesis";"EGFR downregulation";"RHO GTPases activate PAKs";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production"
XP_035740426.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_035718815.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035723662.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035738004.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035736849.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_035718509.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035734298.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_035738058.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213	"Cyclin D associated events in G1";"Myogenesis";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs"
XP_035735963.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035738972.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035717683.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_035726197.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_035725815.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035722727.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035723805.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408	"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_035720394.1	11	Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947	"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035726163.1	13	MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757	"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines"
XP_035730250.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035731533.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035720301.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_035718921.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035734974.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035718513.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035735997.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035739395.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035725687.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_035720253.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035723951.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_035721567.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_035727717.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_035719288.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035731425.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035736634.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035736137.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035724116.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035719013.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_035737514.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_035742504.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035732010.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943	"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_035720614.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035742558.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_035722288.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_035724844.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035724238.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035725937.1	7	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035730073.1	10	Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821	"Galactose catabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification"
XP_035720505.1	7	Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220	"WNT mediated activation of DVL";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"PCP/CE pathway";"RHO GTPases Activate Formins"
XP_035724668.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_035731590.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035741384.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035736264.1	10	KEGG: 00280+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7571;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524	"Valine, leucine and isoleucine degradation";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"PPARA activates gene expression";"Butanoate metabolism";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)"
XP_035726979.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_035726206.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035732177.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035738684.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035737754.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_035739591.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_035732674.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035730334.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_035739504.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035739481.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_035743883.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035724765.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035740430.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_035727888.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035719009.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035736829.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
XP_035741232.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_035718665.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035730299.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035727355.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_035720307.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035725749.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466	"Betanidin degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis"
XP_035735958.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035737538.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_035736715.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035717996.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_035730282.1	10	Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)"
XP_035723957.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035738063.1	17	MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6	"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism"
XP_035735991.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035725681.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events"
XP_035727135.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035723743.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035725415.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035730256.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035741723.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035738362.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035718941.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168333	"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035743048.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_035718802.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035738097.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_035733914.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035726191.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035721536.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035731215.1	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_035741662.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_035736166.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035743975.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_035726104.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_035726607.1	5	Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035742734.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Neutrophil degranulation"
XP_035737040.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035728212.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035731559.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035725931.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_035720988.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_035727551.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035740830.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_035739881.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_035730698.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events"
XP_035742563.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_035736219.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_035731445.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_035734113.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565	"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants"
XP_035729701.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_035732016.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035723176.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035744055.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035728549.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_035732171.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035739487.1	44	Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-5654732;Reactome: R-HSA-9627069;Reactome: R-HSA-8943724;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.24;Reactome: R-HSA-982772;Reactome: R-HSA-2559582;Reactome: R-HSA-6811558;Reactome: R-HSA-1295596;Reactome: R-HSA-2029482;Reactome: R-HSA-112409;Reactome: R-HSA-198753;Reactome: R-HSA-445144;Reactome: R-HSA-881907;Reactome: R-HSA-5654726;Reactome: R-HSA-5675221;Reactome: R-HSA-5654733;Reactome: R-HSA-444257;Reactome: R-HSA-5663213;Reactome: R-HSA-5674135;Reactome: R-HSA-202670;Reactome: R-HSA-8940973;Reactome: R-HSA-6802952;Reactome: R-HSA-5654727;Reactome: R-HSA-2559585;Reactome: R-HSA-6802946;Reactome: R-HSA-879415;Reactome: R-HSA-2559580;Reactome: R-HSA-5674499;Reactome: R-HSA-2871796;Reactome: R-HSA-162658;Reactome: R-HSA-6802948;Reactome: R-HSA-5668599;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-74749;Reactome: R-HSA-9635465;Reactome: R-HSA-450341;Reactome: R-HSA-9634638;Reactome: R-HSA-456926;Reactome: R-HSA-9649948;Reactome: R-HSA-375165	"ESR-mediated signaling";"Frs2-mediated activation";"Negative regulation of FGFR3 signaling";"Regulation of the apoptosome activity";"Regulation of PTEN gene transcription";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Growth hormone receptor signaling";"Senescence-Associated Secretory Phenotype (SASP)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Spry regulation of FGF signaling";"Regulation of actin dynamics for phagocytic cup formation";"RAF-independent MAPK1/3 activation";"ERK/MAPK targets";"Signal transduction by L1";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative regulation of FGFR1 signaling";"Negative regulation of MAPK pathway";"Negative regulation of FGFR4 signaling";"RSK activation";"RHO GTPases Activate WASPs and WAVEs";"MAP2K and MAPK activation";"ERKs are inactivated";"RUNX2 regulates osteoblast differentiation";"Signaling by BRAF and RAF fusions";"Negative regulation of FGFR2 signaling";"Oncogene Induced Senescence";"Signaling by moderate kinase activity BRAF mutants";"Advanced glycosylation endproduct receptor signaling";"Oxidative Stress Induced Senescence";"Negative feedback regulation of MAPK pathway";"FCERI mediated MAPK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by high-kinase activity BRAF mutants";"RHO GTPases Activate NADPH Oxidases";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signal attenuation";"Suppression of apoptosis";"Activation of the AP-1 family of transcription factors";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling downstream of RAS mutants";"NCAM signaling for neurite out-growth"
XP_035728455.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_035724824.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241	"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_035727711.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_035718739.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035741170.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035725094.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035731719.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_035721561.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_035739563.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_035734109.1	11	Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631	"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility"
XP_035742881.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035725001.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035738918.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035720669.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation"
XP_035731596.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035736203.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035724077.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035737462.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035740436.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_035726200.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_035728822.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035742487.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_035740216.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_035743526.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035727152.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_035743908.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738716.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_035744217.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_035729276.1	10	MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042	"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_035724818.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;Reactome: R-HSA-1475029	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide"
XP_035726777.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723733.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035741255.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035732572.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035730400.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035718931.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035727033.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035735477.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_035743038.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_035718252.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035731911.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_035729913.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035722737.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035723222.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_035721277.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035720512.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035742744.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035721520.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_035734584.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_035718245.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035736624.1	14	MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-975634	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport"
XP_035737392.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_035743387.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5856;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5872	"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_035744032.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035726456.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035728432.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035719760.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_035724472.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035739056.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035735516.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035740485.1	7	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism"
XP_035729068.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-111465;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated"
XP_035737389.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I"
XP_035717511.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035720249.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111463	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Neutrophil degranulation";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs"
XP_035736853.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_035741519.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_035739082.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035725927.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism"
XP_035741796.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035740611.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035733506.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035727090.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation"
XP_035725665.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events"
XP_035719501.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035734015.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_035726850.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_035740420.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035739099.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_035733767.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035740446.1	6	KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_035740169.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035725903.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_035737295.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_035741541.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035733744.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035728064.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035731731.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035729733.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035725332.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723909.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035724363.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_035735900.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_035717822.1	13	KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_035724210.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035723547.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_035740781.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035741527.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035724397.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035718598.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035722543.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_035725919.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_035725033.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035718551.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035736945.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035732540.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035721879.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_035726659.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035726100.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035723521.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_035737044.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035742730.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Signal transduction by L1";"Neutrophil degranulation";"Receptor Mediated Mitophagy"
XP_035736636.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035735067.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035721655.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035727802.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035722098.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035729790.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035723068.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035738748.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035743797.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035717212.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035719051.1	13	Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;MetaCyc: PWY-6351;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;MetaCyc: PWY-8052	"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"DAP12 signaling";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis"
XP_035739793.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035721791.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035742506.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035728959.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035730182.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_035724846.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035720847.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035742928.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection"
XP_035724617.1	12	MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1	"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism"
XP_035724820.1	9	MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-6142	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_035719098.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-416476	"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"G-protein activation";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"G alpha (q) signalling events"
XP_035727235.1	5	MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_035741174.1	18	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_035727927.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035720427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035743622.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_035727665.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_035724440.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_035722202.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_035740872.1	7	KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation"
XP_035734654.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035734157.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_035734608.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035724426.1	3	Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import"
XP_035732069.1	9	Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-70263	"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Gluconeogenesis"
XP_035718135.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035735093.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035734443.1	8	KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_035731115.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Activation of ATR in response to replication stress"
XP_035734705.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035733082.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035721518.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110362	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair"
XP_035728996.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736266.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_035723671.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035732676.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035728112.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_035724885.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035718090.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035729743.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_035731741.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035734896.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035732975.1	14	Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121	"Polymerase switching";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI"
XP_035729405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035741531.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_035743544.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035731689.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035721999.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035739740.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035724128.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_035732048.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_035734525.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035720149.1	13	Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-9020702	"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling"
XP_035720466.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035725043.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035731727.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035738946.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-6978	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II"
XP_035734859.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035744253.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_035720860.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035737034.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035736935.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035727370.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035735026.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_035736817.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_035738738.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035732567.1	11	Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035733597.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_035727252.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_035727931.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035718033.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035744117.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035738635.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_035733881.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis"
XP_035734675.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035724836.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035722886.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035738265.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035727001.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035718903.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035728470.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_035726808.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035732593.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_035740668.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_035740424.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035730346.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_035733563.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035718145.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_035731986.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_035724944.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035744280.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035724892.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035727669.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_035743106.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035718139.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035742987.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_035727076.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_035734709.1	182	Reactome: R-HSA-211733;Reactome: R-HSA-8948747;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-8875360;Reactome: R-HSA-174113;Reactome: R-HSA-8863795;Reactome: R-HSA-6791226;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-174048;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-8849469;Reactome: R-HSA-5654727;Reactome: R-HSA-937039;Reactome: R-HSA-5607761;Reactome: R-HSA-5693607;Reactome: R-HSA-2871837;Reactome: R-HSA-69541;Reactome: R-HSA-2979096;Reactome: R-HSA-975144;Reactome: R-HSA-937042;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-1236382;Reactome: R-HSA-1295596;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-901032;Reactome: R-HSA-2559585;Reactome: R-HSA-201681;Reactome: R-HSA-3134975;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-2122947;Reactome: R-HSA-72706;Reactome: R-HSA-1253288;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-68949;Reactome: R-HSA-2173795;Reactome: R-HSA-5689896;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-5362768;Reactome: R-HSA-205043;Reactome: R-HSA-4608870;Reactome: R-HSA-9646399;Reactome: R-HSA-5654733;Reactome: R-HSA-168927;Reactome: R-HSA-6782135;Reactome: R-HSA-3322077;Reactome: R-HSA-400253;Reactome: R-HSA-2467813;Reactome: R-HSA-72764;Reactome: R-HSA-9615710;Reactome: R-HSA-3769402;Reactome: R-HSA-182971;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-195253;Reactome: R-HSA-450302;Reactome: R-HSA-2173791;Reactome: R-HSA-5696395;Reactome: R-HSA-4641258;Reactome: R-HSA-5654732;Reactome: R-HSA-6782210;Reactome: R-HSA-2894862;Reactome: R-HSA-8939236;Reactome: R-HSA-977225;Reactome: R-HSA-9010553;Reactome: R-HSA-5654726;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-156902;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-975956;Reactome: R-HSA-5696394;Reactome: R-HSA-937041;Reactome: R-HSA-8876493;Reactome: R-HSA-6781827;Reactome: R-HSA-2173788;Reactome: R-HSA-5656169;Reactome: R-HSA-9033241;Reactome: R-HSA-6804760;Reactome: R-HSA-5689880;Reactome: R-HSA-3785653;Reactome: R-HSA-2565942;Reactome: R-HSA-69017;Reactome: R-HSA-5684264;Reactome: R-HSA-110314;Reactome: R-HSA-175474;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-917937;Reactome: R-HSA-5358346;Reactome: R-HSA-72649;Reactome: R-HSA-174184;Reactome: R-HSA-2691232;Reactome: R-HSA-5357905;Reactome: R-HSA-5668541;Reactome: R-HSA-174490;Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-6804756;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091;Reactome: R-HSA-9636383;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9645460;Reactome: R-HSA-917729;Reactome: R-HSA-4641257;Reactome: R-HSA-975957;Reactome: R-HSA-936964;Reactome: R-HSA-8951664;Reactome: R-HSA-8866652;Reactome: R-HSA-9613829;Reactome: R-HSA-2672351;Reactome: R-HSA-168928;Reactome: R-HSA-5696397;Reactome: R-HSA-5610783;Reactome: R-HSA-2559580;Reactome: R-HSA-1236974;Reactome: R-HSA-5675482;Reactome: R-HSA-2644606;Reactome: R-HSA-174154;Reactome: R-HSA-6807004;Reactome: R-HSA-2122948;Reactome: R-HSA-1169408;Reactome: R-HSA-1358803;Reactome: R-HSA-72689;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-179409;Reactome: R-HSA-4641263;Reactome: R-HSA-983168;Reactome: R-HSA-5689877;Reactome: R-HSA-8856825;Reactome: R-HSA-912631;Reactome: R-HSA-975163;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-532668;Reactome: R-HSA-162588;Reactome: R-HSA-9013973;Reactome: R-HSA-110312;Reactome: R-HSA-72695;Reactome: R-HSA-6804757;Reactome: R-HSA-5675221;Reactome: R-HSA-5632684;Reactome: R-HSA-5696400;Reactome: R-HSA-5610785;Reactome: R-HSA-2173796;Reactome: R-HSA-936440;Reactome: R-HSA-5656121;Reactome: R-HSA-349425;Reactome: R-HSA-9637628;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-8856828;Reactome: R-HSA-6781823;Reactome: R-HSA-69231;Reactome: R-HSA-9013507;Reactome: R-HSA-5676590;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-69481	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN localization";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"SCF-beta-TrCP mediated degradation of Emi1";"Downregulation of ERBB2 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Negative regulation of FGFR2 signaling";"IRAK1 recruits IKK complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Processing of DNA double-strand break ends";"FCERI mediated NF-kB activation";"Stabilization of p53";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Spry regulation of FGF signaling";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"ER Quality Control Compartment (ERQC)";"Oncogene Induced Senescence";"TCF dependent signaling in response to WNT";"Regulation of innate immune responses to cytosolic DNA";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Downregulation of ERBB4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Orc1 removal from chromatin";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Ovarian tumor domain proteases";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NRIF signals cell death from the nucleus";"Asymmetric localization of PCP proteins";"Aggrephagy";"Negative regulation of FGFR4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Dual incision in TC-NER";"Glycogen synthesis";"Circadian Clock";"Separation of Sister Chromatids";"Eukaryotic Translation Termination";"Late endosomal microautophagy";"Deactivation of the beta-catenin transactivating complex";"EGFR downregulation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Degradation of beta-catenin by the destruction complex";"activated TAK1 mediates p38 MAPK activation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Formation of Incision Complex in GG-NER";"Degradation of DVL";"Negative regulation of FGFR3 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Amyloid fiber formation";"Regulation of expression of SLITs and ROBOs";"Negative regulation of FGFR1 signaling";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Peptide chain elongation";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"DNA Damage Recognition in GG-NER";"IKK complex recruitment mediated by RIP1";"InlA-mediated entry of Listeria monocytogenes into host cells";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Downregulation of TGF-beta receptor signaling";"Termination of translesion DNA synthesis";"Peroxisomal protein import";"Regulation of TP53 Activity through Methylation";"Ub-specific processing proteases";"Myoclonic epilepsy of Lafora";"Regulation of PLK1 Activity at G2/M Transition";"CDK-mediated phosphorylation and removal of Cdc6";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Recognition of DNA damage by PCNA-containing replication complex";"Assembly Of The HIV Virion";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Iron uptake and transport";"Hedgehog ligand biogenesis";"Translation initiation complex formation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of TNFR1 signaling";"TNFR2 non-canonical NF-kB pathway";"Membrane binding and targetting of GAG proteins";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells";"Prevention of phagosomal-lysosomal fusion";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Alpha-protein kinase 1 signaling pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Degradation of AXIN";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Neddylation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Chaperone Mediated Autophagy";"Stimuli-sensing channels";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Degradation of GLI2 by the proteasome";"Oxidative Stress Induced Senescence";"ER-Phagosome pathway";"Regulation of necroptotic cell death";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of MET activity";"Activated NOTCH1 Transmits Signal to the Nucleus";"ISG15 antiviral mechanism";"Downregulation of ERBB2:ERBB3 signaling";"Formation of a pool of free 40S subunits";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of FZD by ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of signaling by CBL";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Budding and maturation of HIV virion";"TICAM1-dependent activation of IRF3/IRF7";"Translesion synthesis by REV1";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of TP53 Degradation";"Negative regulation of MAPK pathway";"Hedgehog 'on' state";"Dual Incision in GG-NER";"GLI3 is processed to GLI3R by the proteasome";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulators of DDX58/IFIH1 signaling";"Translesion synthesis by POLI";"Autodegradation of the E3 ubiquitin ligase COP1";"Modulation by Mtb of host immune system";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Cyclin D associated events in G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NIK-->noncanonical NF-kB signaling";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints"
XP_035724710.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035728942.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035737698.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035730195.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035720488.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_035718396.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_035738781.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_035721659.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035743690.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035744007.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035718211.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035731103.1	9	Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616	"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_035729101.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_035725837.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035731078.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035738649.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035742660.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;MetaCyc: PWY-7511	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination"
XP_035737795.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035733869.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035737256.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035742637.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_035726642.1	10	KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism"
XP_035740961.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035743263.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035742134.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035726758.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035719702.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035733414.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035740377.1	7	Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72702	"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition"
XP_035742308.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035723035.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035736507.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250	"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_035732450.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway"
XP_035730026.1	12	Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6277;MetaCyc: PWY-6613;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9	"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Biotin transport and metabolism";"One carbon pool by folate"
XP_035722147.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035743475.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis"
XP_035739267.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035721875.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_035722702.1	7	Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events";"Platelet degranulation";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_035726655.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035722644.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035726518.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_035722868.1	32	Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-113418	"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex"
XP_035741451.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035721291.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_035735581.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_035733140.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035720342.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035738834.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035735458.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_035717496.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035743297.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_035734874.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035741857.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
XP_035723905.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035717586.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035721316.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035729290.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_035735491.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035717843.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_035717151.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035733167.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035738269.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035726999.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035728974.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035736689.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_035739571.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system"
XP_035724934.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_035732694.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_035742240.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035736692.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_035718466.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035726982.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035725821.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035719984.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035733272.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035735336.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035736741.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_035731570.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_035724058.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035730392.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035736968.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_035718860.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035724004.1	22	MetaCyc: PWY-8013;MetaCyc: PWY-7238;MetaCyc: PWY-7385;MetaCyc: PWY-5384;MetaCyc: PWY-5514;MetaCyc: PWY-3801;Reactome: R-HSA-70263;Reactome: R-HSA-6798695;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-6981;MetaCyc: PWY-622;MetaCyc: PWY-6992;MetaCyc: PWY-7347;MetaCyc: PWY-5659;KEGG: 00010+5.3.1.9;MetaCyc: PWY-621;MetaCyc: PWY-5054;KEGG: 00030+5.3.1.9;KEGG: 00500+5.3.1.9;Reactome: R-HSA-5628897;KEGG: 00520+5.3.1.9	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Gluconeogenesis";"Neutrophil degranulation";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Chitin biosynthesis";"Starch biosynthesis";"1,5-anhydrofructose degradation";"Sucrose biosynthesis III";"GDP-mannose biosynthesis";"Glycolysis / Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"D-sorbitol biosynthesis I";"Pentose phosphate pathway";"Starch and sucrose metabolism";"TP53 Regulates Metabolic Genes";"Amino sugar and nucleotide sugar metabolism"
XP_035735199.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035739226.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035719522.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_035742571.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)"
XP_035738300.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035741600.1	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_035725847.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_035732163.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035717423.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035728303.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_035736727.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_035736288.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035735977.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174184	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_035725396.1	7	KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7219;MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II"
XP_035738424.1	18	Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-1221632;MetaCyc: PWY-7511;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554	"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Meiotic synapsis";"Protein ubiquitination";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035741080.1	3	Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2	"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway"
XP_035738668.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_035727786.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476	"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1"
XP_035726632.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_035742144.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035739410.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_035736939.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035736013.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_035730030.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035740265.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035717535.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035720374.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035738765.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-191859	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"snRNP Assembly"
XP_035730612.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035734901.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
YP_009915660.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035718837.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035739816.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_035717970.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035720903.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035739144.1	11	MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis"
XP_035729409.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035723133.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825	"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis"
XP_035738992.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723086.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_035738071.1	1	Reactome: R-HSA-156581	"Methylation"
XP_035728682.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_035741207.1	7	MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis"
XP_035734031.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_035738116.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_035720145.1	13	Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-9014325	"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_035719264.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_035736009.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035733130.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035721995.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035729502.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_035734278.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_035737156.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_035718307.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035724508.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035744284.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035742234.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035742848.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035737565.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_035726028.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035742193.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035718735.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035724926.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035734105.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035744096.1	8	MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-2301;MetaCyc: PWY-6372;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4	"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis"
XP_035733571.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035734757.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035731618.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035735324.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_035722247.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_035739167.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035729606.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_035727821.1	3	Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807	"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling"
XP_035720768.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_035739664.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035724714.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_035731166.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775	"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis"
XP_035731449.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_035720941.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035719221.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_035727441.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035721607.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035728890.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035740063.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035738148.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035743694.1	6	Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067	"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_035734517.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_035731542.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035721338.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035742167.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035727847.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035743601.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_035742428.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282	"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_035738893.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035742664.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_035722221.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035721369.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_035725864.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035737977.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_035727396.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035743081.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035717942.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035736452.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359	"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation"
XP_035719626.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035732454.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway"
XP_035742350.1	4	Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_035732408.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035730871.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035741813.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins"
XP_035729052.1	11	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_035723413.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_035727211.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035722640.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035731219.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035729353.1	7	KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10	"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes"
XP_035718669.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035724873.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035721200.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035739130.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035723502.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035730295.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035744125.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_035727359.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-400042	"G-protein activation";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_035731398.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035729086.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035720739.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_035731131.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035718076.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035733144.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035739350.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_035729201.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035731203.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035736486.1	4	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis"
XP_035722811.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035725648.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035729329.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_035736188.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035726495.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035725669.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035718403.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_035741515.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944	"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2"
XP_035734302.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035719237.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035728970.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035720094.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035724930.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035725111.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035743771.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_035739095.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_035740165.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035737346.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_035717682.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_035735962.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035720286.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035718864.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_035723194.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035723101.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_035720252.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035738358.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035722164.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_035718419.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_035726520.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_035738304.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_035735698.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_035732106.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Purine salvage";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation"
XP_035720931.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035723233.1	25	Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Gap junction assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids"
XP_035726162.1	13	MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757	"L-histidine degradation III";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines"
XP_035724575.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_035737385.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis"
XP_035741604.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_035729776.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_035735795.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_035738216.1	17	MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Carnitine metabolism";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism"
XP_035718512.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035731532.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035734683.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035717251.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035719012.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_035726014.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695	"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Rho GTPase cycle";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling"
XP_035720415.1	7	Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400	"WNT mediated activation of DVL";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"PCP/CE pathway"
XP_035738446.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_035722309.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035732297.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_035727860.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_035718249.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035719309.1	18	KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00400+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1	"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Arginine biosynthesis";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism"
XP_035724680.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_035730034.1	14	MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)"
XP_035720370.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035731624.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035738611.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
YP_009915664.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_035738485.1	22	MetaCyc: PWY-5353;MetaCyc: PWY-7602;MetaCyc: PWY-6958;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7592;MetaCyc: PWY-7724;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7726;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-6598	"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Sciadonate biosynthesis"
XP_035722313.1	14	Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055	"Synthesis of PA";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_035720749.1	13	Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398	"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway"
XP_035735299.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035739126.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035725735.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_035724728.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035733308.1	26	Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-8941856	"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling"
XP_035739140.1	11	MetaCyc: PWY-7184;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism"
XP_035743899.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_035720681.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035725638.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_035737491.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035732310.1	13	KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66	"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine catabolism";"Purine metabolism"
XP_035730991.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035724371.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035737458.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035733134.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035731141.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035720966.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_035741259.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035721589.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035728209.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035729349.1	7	KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10	"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_035723691.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035718725.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035740889.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_035743348.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035735108.1	5	KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_035723742.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035720937.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035738062.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs"
XP_035723658.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035727831.1	5	Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20	"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism"
XP_035739438.1	11	Reactome: R-HSA-8862803;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-6796648;Reactome: R-HSA-2871796;Reactome: R-HSA-8943724	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Transcription of DNA Repair Genes";"FCERI mediated MAPK activation";"Regulation of PTEN gene transcription"
XP_035741233.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_035718819.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_035718464.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035719986.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035725070.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_035718780.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035732100.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_035726526.1	23	Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-418217	"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (z) signalling events";"G alpha (q) signalling events";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"G-protein activation";"G beta:gamma signalling through PLC beta"
XP_035739773.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_035741663.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_035734064.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_035738363.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035725614.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035741722.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035725117.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619	"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN"
XP_035742438.1	6	KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;Reactome: R-HSA-73817	"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis"
XP_035736543.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_035718803.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035729770.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_035738440.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_035735250.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035723259.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035727866.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035725394.1	7	MetaCyc: PWY-7219;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2	"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine metabolism"
XP_035742814.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_035743499.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035728157.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035738426.1	18	Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-1221632	"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Protein ubiquitination";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic synapsis"
XP_035739185.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035729498.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035728705.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-2151201	"UCH proteinases";"HATs acetylate histones";"Transcriptional activation of mitochondrial biogenesis"
XP_035720687.1	8	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035742562.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_035720376.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035724961.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_035728443.1	13	Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-5689877;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511	"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"Josephin domain DUBs";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"HSF1 activation"
XP_035731644.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_035734112.1	11	Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631	"PIP3 activates AKT signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility"
XP_035733631.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035734996.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9619483	"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs"
XP_035724377.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035724686.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035731868.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_035721856.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035720729.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_035723296.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035739120.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035724748.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_035739562.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_035738846.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035734959.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332	"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Gap junction assembly";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin"
XP_035727460.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035724645.1	14	MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_035738820.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035736202.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035732316.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035737275.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_035719266.1	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
XP_035727129.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_035720947.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Removal of the Flap Intermediate";"DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_035727447.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035723732.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035721601.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035737609.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333	"snRNP Assembly";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035720753.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775	"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"Ion homeostasis"
XP_035724920.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035731984.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_035720509.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035737150.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_035732573.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035724946.1	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4	"Arachidonic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism"
XP_035733285.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"DNA replication initiation";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_035730750.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_035727074.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_035729600.1	12	MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340	"Sulfite oxidation III";"Selenocompound metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Sulfur metabolism";"Selenate reduction";"Monobactam biosynthesis";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation"
XP_035734511.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_035724769.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035720402.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035727153.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035743607.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-983231	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production"
XP_035723774.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035720513.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035734695.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035718301.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035723223.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_035731160.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9620244	"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion homeostasis";"HSF1-dependent transactivation";"Interferon gamma signaling";"Long-term potentiation"
XP_035738861.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035718394.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035718253.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035740058.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_035729912.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035734751.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035733220.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035738467.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_035733246.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035725578.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_035727610.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035740091.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035719935.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_035725780.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035733416.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035739382.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035734470.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035739399.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035733641.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035735783.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_035731634.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_035744033.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035736425.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_035731137.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107	"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_035722646.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035737393.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_035724473.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035722817.1	39	Reactome: R-HSA-5654228;Reactome: R-HSA-5654693;Reactome: R-HSA-5654688;Reactome: R-HSA-2219530;Reactome: R-HSA-5658623;Reactome: R-HSA-190373;Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-190371;Reactome: R-HSA-6811558;Reactome: R-HSA-5654221;Reactome: R-HSA-5654219;Reactome: R-HSA-5654712;Reactome: R-HSA-5654699;Reactome: R-HSA-5654720;Reactome: R-HSA-5654704;Reactome: R-HSA-5655253;Reactome: R-HSA-5654719;Reactome: R-HSA-5654732;Reactome: R-HSA-1839122;Reactome: R-HSA-190322;Reactome: R-HSA-190375;Reactome: R-HSA-8853338;Reactome: R-HSA-5654706;Reactome: R-HSA-1839130;Reactome: R-HSA-190372;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-5654710;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-5654687;Reactome: R-HSA-2033519;Reactome: R-HSA-2033514;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-5654689;Reactome: R-HSA-5654727;Reactome: R-HSA-1257604	"Phospholipase C-mediated cascade, FGFR4";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFRL1 modulation of FGFR1 signaling";"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"FGFR3b ligand binding and activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2";"Phospholipase C-mediated cascade: FGFR1";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR2";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR3";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR4";"Negative regulation of FGFR3 signaling";"Signaling by activated point mutants of FGFR1";"FGFR4 ligand binding and activation";"FGFR2c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"FRS-mediated FGFR3 signaling";"Signaling by activated point mutants of FGFR3";"FGFR3c ligand binding and activation";"RAF/MAP kinase cascade";"PI3K Cascade";"PI-3K cascade:FGFR3";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"Downstream signaling of activated FGFR1";"Activated point mutants of FGFR2";"FGFR3 mutant receptor activation";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"PI-3K cascade:FGFR1";"Negative regulation of FGFR2 signaling";"PIP3 activates AKT signaling"
XP_035734315.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035728433.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035730024.1	12	KEGG: 00670+2.1.2.9;Reactome: R-HSA-196780;MetaCyc: PWY-6613;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;Reactome: R-HSA-73817	"One carbon pool by folate";"Biotin transport and metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_035742356.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035744145.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_035724738.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035722788.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_035721206.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035736845.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-3769402;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Deactivation of the beta-catenin transactivating complex";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids"
XP_035731264.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_035732808.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768	"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_035718505.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases"
XP_035743087.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035725819.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035739083.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_035721314.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035737089.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035736852.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035719788.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035734876.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035717494.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035732995.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_035736590.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035735406.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-418555	"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"G alpha (q) signalling events";"G alpha (s) signalling events"
XP_035727217.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035739356.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035733448.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-6842;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-2261;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;Reactome: R-HSA-156590	"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation"
XP_035724362.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_035735150.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_035720096.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035722715.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035719715.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035725841.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_035720284.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035736721.1	5	MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_035722829.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035729732.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035718784.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_035738306.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_035732104.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_035720059.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035723196.1	18	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition"
XP_035739220.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035742285.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035725421.1	10	Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-5628897	"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes"
XP_035723912.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035739577.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_035732338.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035722542.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_035725610.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035729223.1	14	Reactome: R-HSA-1483213;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4	"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Triglyceride biosynthesis";"Synthesis of PC";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism"
XP_035724063.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_035741606.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_035729774.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_035725032.1	3	KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle"
XP_035736747.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_035738214.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-6722;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679	"Carnitine metabolism";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"Pyruvate metabolism";"Fatty acid biosynthesis";"Propanoate metabolism";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis"
XP_035717705.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_035739792.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035717213.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035737800.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035724918.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035717360.1	7	Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693571	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)"
XP_035742810.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_035723207.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035726016.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035742124.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035731626.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035727803.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
YP_009915666.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035723025.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035722219.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035735393.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2	"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Photosynthesis"
XP_035730036.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035735092.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035734442.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035722351.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035728113.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_035739810.1	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_035719131.1	4	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism"
XP_035717209.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_035742641.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035734549.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035733136.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035740873.1	7	KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_035727628.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-9029569	"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_035743623.1	4	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_035722131.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035727819.1	3	Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807	"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling"
XP_035734455.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035734907.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035719351.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035742789.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_035735089.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035729813.1	3	MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17	"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism"
XP_035731811.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035719574.1	7	KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1483226	"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PI"
XP_035724165.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035739079.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
XP_035724924.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035731980.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035744286.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035738787.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035726479.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035744001.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035743659.1	4	KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;Reactome: R-HSA-5661270	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Formation of xylulose-5-phosphate"
XP_035730708.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706	"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling"
XP_035729742.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_035739666.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035735340.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035722574.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035725831.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_035720888.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_035731693.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035728584.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035740575.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
XP_035723770.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_035739118.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035724599.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_035735779.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_035742079.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035721106.1	4	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake"
XP_035724716.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_035731925.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035731164.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946	"RAF activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants"
XP_035724489.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035730862.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_035738818.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035736737.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519	"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression"
XP_035730514.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_035725042.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_035727614.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035722532.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_035736305.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035717347.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_035727117.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035721633.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035740680.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783	"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type"
XP_035725784.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035727301.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_035738434.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_035734474.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_035717525.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035731630.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035733185.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_035741898.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_035718610.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035732456.1	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035735497.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_035741851.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035723451.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035718333.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035731313.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_035740625.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins"
XP_035729084.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035741035.1	5	MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate"
XP_035740371.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_035732482.1	7	MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_035733562.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035718153.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035718841.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035718902.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035732499.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924	"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Macroautophagy";"Intraflagellar transport"
XP_035735275.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_035729296.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035733146.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035722141.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035740728.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035717490.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_035738579.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_035725460.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038	"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"VLDL assembly";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Chylomicron clearance";"Post-translational protein phosphorylation";"LDL clearance"
XP_035741480.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035738024.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035727933.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035718031.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035723880.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035743938.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035740154.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035729939.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035735889.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_035733700.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-5619078;Reactome: R-HSA-6787639	"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis"
XP_035718278.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035740073.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_035727302.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_035736413.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_035729288.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_035717717.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035733883.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_035735944.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_035723703.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035734323.1	6	KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Chitin derivatives degradation"
XP_035718994.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_035723825.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035719155.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-191859	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"snRNP Assembly"
XP_035722142.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035720675.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035718842.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035718901.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035727003.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035738877.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035723486.1	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901	"Scavenging by Class F Receptors";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"LDL remodeling";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"VLDL clearance";"Chylomicron clearance";"Post-translational protein phosphorylation";"LDL clearance";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron remodeling"
XP_035717557.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035719335.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035740372.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_035732558.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_035718855.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035723719.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354	"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Lipophagy"
XP_035733561.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035722155.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035726647.1	10	KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_035741533.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035729692.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035725832.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035731957.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035725027.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035744002.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035731743.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035729741.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_035720490.1	8	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_035718066.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_035734860.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035743688.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035730493.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035742524.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_035721740.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035728947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035734149.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035725874.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_035733536.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-110362	"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair"
XP_035724404.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_035725041.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_035724491.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_035724897.1	6	Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis"
XP_035732395.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035739956.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035730861.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_035742999.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN"
XP_035728513.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_035718874.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_035729507.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_035720337.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035724336.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035722174.1	6	KEGG: 00300+4.3.3.7;MetaCyc: PWY-8088;MetaCyc: PWY-5097;MetaCyc: PWY-2941;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2942	"Lysine biosynthesis";"Dipicolinate biosynthesis";"L-lysine biosynthesis VI";"L-lysine biosynthesis II";"Monobactam biosynthesis";"L-lysine biosynthesis III"
XP_035727757.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035720705.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_035729949.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035743500.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_035720654.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_035732050.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_035736317.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035739704.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035729766.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_035727105.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_035740344.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035743075.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035721793.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035737940.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035729884.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035730114.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_035733670.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802955	"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_035722345.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809	"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization"
XP_035725679.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_035719352.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035741051.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035730617.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035728960.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035736290.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035728815.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035740175.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035742704.1	7	Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381042	"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"Platelet degranulation";"PERK regulates gene expression"
XP_035735004.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_035742642.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035719345.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035738963.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_035722352.1	31	MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-4381;MetaCyc: PWY-7746;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-8049;MetaCyc: PWY-5973;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-5366;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;Reactome: R-HSA-9029558	"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Pederin biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_035731564.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_035735187.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_035718713.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_035731733.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035729731.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035717125.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035735684.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035741543.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035725842.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035722527.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_035740783.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035725855.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_035728937.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_035732273.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035724361.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_035732724.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751	"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity"
XP_035742879.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035720209.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035730397.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035730210.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201	"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis"
XP_035743736.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_035725031.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_035718553.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035717180.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035736233.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035727870.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035723911.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035720360.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035739879.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035723884.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035738020.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035741484.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035731380.1	19	MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-163765;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-6798695	"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Neutrophil degranulation"
XP_035720015.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035738046.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_035733758.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035740609.1	11	Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-5695	"Purine catabolism";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation II";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Inosine 5'-phosphate degradation"
XP_035723949.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_035717513.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035739381.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035735554.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035735940.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_035717921.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy"
XP_035731068.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035721056.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035725105.1	8	KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27	"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_035719796.1	8	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241	"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_035740613.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035734249.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035732075.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035721082.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_035733518.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035741929.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035729673.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035730228.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035736851.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035744198.1	11	MetaCyc: PWY-6608;MetaCyc: PWY-6607;MetaCyc: PWY-5381;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-7185;MetaCyc: PWY-6606;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5	"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Purine metabolism";"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism"
XP_035732500.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_035736905.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_035735714.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035736457.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_035742381.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_035726126.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035737972.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035717753.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_035717509.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035737058.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035739670.1	10	Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-2151209	"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_035726095.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035728888.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035720584.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
XP_035720401.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035722878.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035738708.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035731547.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035720494.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035727994.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035734512.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035738605.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_035742546.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206	"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha"
XP_035736329.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_035724806.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035721744.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972	"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035727855.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035721602.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_035723731.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035732736.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_035734786.1	14	KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201	"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Photorespiration ";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Methane metabolism";"Glycine betaine degradation I";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Folate transformations I"
XP_035727278.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035740971.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035743273.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035740092.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035729911.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035734752.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035729523.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_035718933.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035738862.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035734745.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035721865.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_035728717.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_035742585.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-163765	"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression"
XP_035739520.1	5	MetaCyc: PWY-6168;Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism"
XP_035740089.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035718870.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_035734111.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631	"Signaling by ERBB2";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility"
XP_035743591.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035742561.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_035725019.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035739883.1	33	KEGG: 00625+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-7111;MetaCyc: PWY-6587;KEGG: 00982+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5078;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7798;KEGG: 00071+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-7118;MetaCyc: PWY-7396;Reactome: R-HSA-71384;MetaCyc: PWY-6871;MetaCyc: PWY-6333;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5082;MetaCyc: PWY-6313;MetaCyc: PWY-5480;MetaCyc: PWY-6342;MetaCyc: PWY-1801;KEGG: 00626+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5076;MetaCyc: PWY-3162;MetaCyc: PWY-5057	"Chloroalkane and chloroalkene degradation";"L-phenylalanine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Pyruvate fermentation to ethanol III";"Drug metabolism - cytochrome P450";"alpha-Linolenic acid metabolism";"Metabolism of xenobiotics by cytochrome P450";"(S)-propane-1,2-diol degradation";"Glycine, serine and threonine metabolism";"Phenylethanol biosynthesis";"L-isoleucine degradation II";"Glycolysis / Gluconeogenesis";"Protein S-nitrosylation and denitrosylation";"Fatty acid degradation";"Tyrosine metabolism";"Salidroside biosynthesis";"Chitin degradation to ethanol";"Butanol and isobutanol biosynthesis (engineered)";"Ethanol oxidation";"3-methylbutanol biosynthesis (engineered)";"Acetaldehyde biosynthesis I";"Retinol metabolism";"Pyruvate fermentation to ethanol II";"L-methionine degradation III";"Serotonin degradation";"Pyruvate fermentation to ethanol I";"Noradrenaline and adrenaline degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Naphthalene degradation";"Methane metabolism";"L-leucine degradation III";"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II"
XP_035728180.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_035730077.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_035731794.1	40	Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167200	"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_035725933.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-72086	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"mRNA Capping"
XP_035724962.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_035740326.1	5	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_035732054.1	9	KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;Reactome: R-HSA-70263;Reactome: R-HSA-196780;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis";"Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism"
XP_035720650.1	6	MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis"
XP_035732008.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943	"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_035743887.1	8	Reactome: R-HSA-191273;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922	"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I"
XP_035734669.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035719170.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_035729452.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_035721597.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035723013.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_035740340.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation"
XP_035723939.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_035720109.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035736201.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035733674.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_035729596.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_035733177.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035717280.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035740779.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035739561.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035721563.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035728964.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035736294.1	5	MetaCyc: PWY-7919;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_035727713.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_035725178.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_035723009.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035735000.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-389960	"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Gap junction assembly";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC"
XP_035743615.1	4	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_035731560.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_035727027.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_035723689.1	22	KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-6958;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7726;Reactome: R-HSA-75876;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7035	"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_035731537.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035718517.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035728284.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035726664.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035719662.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035726167.1	13	MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9	"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"One carbon pool by folate";"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes"
XP_035722274.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_035723741.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035738061.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"Macroautophagy";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035719274.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_035734268.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434	"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035738678.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333	"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035717687.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_035730214.1	9	Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472	"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035735967.1	7	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-373753;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-203641;Reactome: R-HSA-418885	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Nephrin family interactions";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"NOSTRIN mediated eNOS trafficking";"DCC mediated attractive signaling"
XP_035732688.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation"
XP_035736190.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035727874.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035726848.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_035723727.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035720364.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism"
XP_035730306.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035726193.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_035742028.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway"
XP_035734735.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035732785.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_035741378.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_035738612.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_035736207.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_035717245.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035718876.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5358752	"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated"
XP_035739567.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035734070.1	9	MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_035740346.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_035736025.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735936.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_035724657.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_035729886.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035721718.1	5	Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-166208	"AKT phosphorylates targets in the cytosol";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTORC1-mediated signalling"
XP_035720656.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_035719384.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035719011.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-977225	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Amyloid fiber formation"
XP_035741312.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035717252.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035730424.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035730668.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035729764.1	6	MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Galactose metabolism"
XP_035724372.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035741939.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035730844.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
XP_035728145.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_035718315.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035720682.1	6	Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537	"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_035730992.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035743487.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035743881.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035721481.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035739483.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_035730989.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035739593.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_035731155.1	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_035736600.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_035727047.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035717681.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_035718751.1	6	MetaCyc: PWY-6731;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238	"Starch degradation III";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II"
XP_035738093.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_035735961.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035725112.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035743772.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_035735686.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035722405.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035741727.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035742530.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_035732726.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_035726603.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway"
XP_035736339.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035732379.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035718511.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740897.1	12	KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Ether lipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
XP_035718923.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035720303.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035731531.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035733950.1	10	MetaCyc: PWY-5691;Reactome: R-HSA-975634;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171	"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Urate conversion to allantoin II";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions"
XP_035733544.1	10	Reactome: R-HSA-69205;KEGG: 00670+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184	"G1/S-Specific Transcription";"One carbon pool by folate";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_035730639.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035730300.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035723102.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_035723953.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035720251.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035721395.1	3	Reactome: R-HSA-5673001;Reactome: R-HSA-4420097;Reactome: R-HSA-167044	"RAF/MAP kinase cascade";"VEGFA-VEGFR2 Pathway";"Signalling to RAS"
XP_035738067.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035720932.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035717415.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035720298.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035735748.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035727212.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035740565.1	25	Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-381771;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-418217	"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"G alpha (q) signalling events";"G alpha (s) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta"
XP_035718959.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_035738026.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035729098.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_035731386.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035730872.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035722790.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_035723929.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035736451.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation"
XP_035719790.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Activation of RAC1";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035733763.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035721050.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035735920.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035726185.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035735946.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_035719564.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_035731345.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035733797.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035734229.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism"
XP_035731132.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035741949.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035743383.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183	"Streptomycin biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_035718996.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_035730248.1	52	Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-167152	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_035729202.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035726469.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_035728355.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035725695.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_035731352.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723501.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035721465.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035743910.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035727822.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902	"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity"
XP_035731527.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035727037.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035729917.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035733572.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035737918.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism"
XP_035739038.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035734780.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-1622;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1	"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"Methane metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Folate polyglutamylation";"Photorespiration ";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_035732730.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_035718064.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_035719733.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035742540.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels"
XP_035739271.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035743744.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_035720407.1	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_035727455.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035720955.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_035744213.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035727549.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035721189.1	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism"
XP_035734628.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035735635.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_035734464.1	8	KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis"
XP_035725876.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_035731541.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035724406.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042	"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_035739526.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035744088.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035723305.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035728598.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_035739954.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_035719222.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035727442.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035720942.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035723737.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_035742271.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035730611.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035731796.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035734153.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035727923.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035725212.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-428540	"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Downstream signal transduction";"Activation of RAC1"
XP_035737769.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
XP_035743767.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035718432.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035735097.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035734447.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035719380.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035740324.1	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_035729760.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035737920.1	7	KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500	"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle"
XP_035729501.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_035728966.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035736296.1	5	MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-532668;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_035743793.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035730840.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
XP_035738958.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_035733387.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_035738072.1	1	Reactome: R-HSA-156581	"Methylation"
XP_035728681.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035733676.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_035724613.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035718474.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035728749.1	8	KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27	"Propanoate metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis"
XP_035720198.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_035728286.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035733271.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035731878.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035736742.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_035739479.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_035736691.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_035741523.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-5981	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III"
XP_035725822.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035724393.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_035724254.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035723917.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035739572.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_035719547.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035724208.1	6	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_035728001.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_035717903.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-936440	"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling"
XP_035735918.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035734390.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035717152.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_035733908.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-8939211	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase";"ESR-mediated signaling"
XP_035730216.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha"
XP_035733526.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035722039.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560	"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Triglyceride catabolism"
XP_035719521.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_035733895.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_035730304.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_035739534.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_035724971.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035732910.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035736515.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_035724367.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035731255.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035723764.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_035738044.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035741596.1	3	KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_035718549.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035723886.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035724340.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_035741486.1	5	Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16	"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035731170.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719	"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Long-term potentiation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors"
XP_035726789.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_035722794.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5578749	"Nuclear import of Rev protein";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs"
XP_035744109.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_035741719.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035735924.1	17	Reactome: R-HSA-1834949;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-3270619;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586	"Cytosolic sensors of pathogen-associated DNA";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"IRF3-mediated induction of type I IFN";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence"
XP_035721054.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035719794.1	8	MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_035725568.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_035726641.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_035735556.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035740962.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035719701.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035719560.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_035733593.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_035744113.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035718037.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035735492.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035720341.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035735582.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_035741559.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035718822.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035736813.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_035733483.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035737281.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035728739.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_035721292.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_035735599.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035717711.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_035723480.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_035735716.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035726124.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035726965.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035738295.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_035735489.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035741452.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids"
XP_035727112.1	7	KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism"
XP_035744257.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_035720496.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035722537.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_035731723.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035730867.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035724891.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035732734.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_035734784.1	14	MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1	"Glycine betaine degradation I";"Methane metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate polyglutamylation";"Photorespiration ";"Glycine, serine and threonine metabolism"
XP_035742544.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-400206	"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha"
XP_035718060.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_035724804.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035736223.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_035729953.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035718212.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_035734460.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035731805.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035721785.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035726220.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6781823	"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex"
XP_035739950.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035726577.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035719049.1	13	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;MetaCyc: PWY-6351;Reactome: R-HSA-9027277	"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)"
XP_035719047.1	13	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-202433;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;MetaCyc: PWY-6351;Reactome: R-HSA-9027277	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Generation of second messenger molecules";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)"
XP_035735734.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_035742034.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_035739072.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035726579.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035729681.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035728501.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035743748.1	13	MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5	"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_035723135.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_035726472.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035743652.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_035718325.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035720457.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035734624.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035730140.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_035741023.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_035730414.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035743686.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035737914.1	7	Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2	"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis"
XP_035742072.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035739034.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035740263.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035724482.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035736015.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035730869.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035721371.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_035732165.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035717425.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035720776.1	12	Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-383280;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580	"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Nuclear Receptor transcription pathway";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence"
XP_035724777.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035723551.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
XP_035732556.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_035735597.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035721287.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035741557.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035727011.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_035729252.1	3	KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_035718039.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_035717764.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035729931.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035730244.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_035730838.1	5	MetaCyc: PWY-7185;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2	"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism"
XP_035721000.1	9	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol"
XP_035729286.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_035734439.1	3	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation"
XP_035733569.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035718276.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035744107.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035729001.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035731003.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_035726787.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_035732582.1	9	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-110314	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex"
XP_035718547.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035717845.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035724369.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035743635.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation"
XP_035720133.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035740454.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035740408.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035730350.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_035732918.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_035735602.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035720294.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035735744.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035737730.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035722037.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035724087.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_035725909.1	8	KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_035733548.1	7	MetaCyc: PWY-6614;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757	"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines"
XP_035743738.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_035722822.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035726653.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035721873.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_035724200.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035743473.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035734351.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035719549.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035723033.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035726077.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_035731870.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122	"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035720045.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035722907.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_035718794.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035743265.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_035727222.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035719212.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035737793.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035739799.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_035726214.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035728747.1	8	MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate"
XP_035731105.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_035720190.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035725068.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_035733392.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_035739516.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand"
XP_035718049.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_035738950.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-6708;Reactome: R-HSA-2142789	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
XP_035730234.1	10	Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-72702	"Recycling of eIF2:GDP";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"Ribosomal scanning and start codon recognition"
XP_035733389.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_035731943.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035729941.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035744223.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_035730193.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_035724607.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035723090.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035728721.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_035742799.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-167590	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation"
XP_035734449.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035735099.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade"
XP_035734166.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_035724104.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035721714.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035743769.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035739756.1	6	KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_035729768.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_035724191.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035725325.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035734542.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7291;Reactome: R-HSA-9033241	"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import"
XP_035733093.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730272.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035717835.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035727812.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035743920.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035725671.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_035726836.1	52	Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-76071;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-1834949;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-5617472	"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035723739.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035742030.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation"
XP_035719315.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035720502.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_035729332.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035733295.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035742612.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035724623.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035725733.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_035719470.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035724762.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035730647.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035731901.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035730144.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_035727276.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035738567.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035731422.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035737910.1	7	Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism"
XP_035730410.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035744025.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035740081.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035734788.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685	"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy"
XP_035736347.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035724808.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035725478.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_035738706.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035731529.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035727039.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035743918.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035727913.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035733871.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035728886.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035722876.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035730621.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035733782.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035737056.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035723941.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035719923.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035723802.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409	"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_035735793.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035726467.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159236	"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035723235.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035722923.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440	"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_035730226.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472	"PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035741947.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035744196.1	11	MetaCyc: PWY-7185;MetaCyc: PWY-7821;MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-6607;MetaCyc: PWY-5381	"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)"
XP_035733799.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035734227.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism"
XP_035741509.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035717501.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035731066.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035721004.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035734935.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035721058.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_035719798.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_035732985.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035717484.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035719751.1	12	KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142	"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_035725564.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035725812.1	5	Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109	"Methionine salvage pathway";"Regulation of the apoptosome activity";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_035733756.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035741513.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_035718405.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_035744159.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035735767.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035718743.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035719112.1	10	Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9	"Metabolism of folate and pterines";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes"
XP_035735726.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035730354.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035740882.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035742026.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism"
XP_035741376.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_035738069.1	31	MetaCyc: PWY-8047;MetaCyc: PWY-7388;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-7858;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-8049;Reactome: R-HSA-75105;MetaCyc: PWY-6519;MetaCyc: PWY-5989	"Bryostatin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)"
XP_035737734.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035720290.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035730134.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035718812.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035732961.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035725743.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442	"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Regulation of RAS by GAPs"
XP_035744123.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_035722996.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035732377.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035734636.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_035724875.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_035727537.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035729355.1	7	KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10	"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes"
XP_035732686.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035736337.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-5676590	"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Regulation of RAS by GAPs";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling"
XP_035726885.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_035734266.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8852276	"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_035723415.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_035724204.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway"
XP_035735914.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_035719959.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_035739040.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035740856.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035731874.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035726426.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035722959.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035724316.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035723931.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035736088.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_035720101.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035723252.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035736213.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_035742569.1	31	MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-7388;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-6799;MetaCyc: PWY-7858;Reactome: R-HSA-163765;Reactome: R-HSA-199220;MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-8012	"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis"
XP_035727794.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_035740065.1	60	KEGG: 00410+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77346;MetaCyc: PWY-7779;MetaCyc: PWY-7726;MetaCyc: PWY-6944;Reactome: R-HSA-77288;Reactome: R-HSA-77348;MetaCyc: PWY-7656;MetaCyc: PWY-5177;MetaCyc: PWY-7778;MetaCyc: PWY-7401;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-7216;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-6945;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-6883;MetaCyc: PWY-1361;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00720+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00640+4.2.1.17;Reactome: R-HSA-77350;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-5136;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00362+4.2.1.17;KEGG: 00280+4.2.1.17;Reactome: R-HSA-1482798;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094	"beta-Alanine metabolism";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Tryptophan metabolism";"Butanoate metabolism";"Fatty acid degradation";"Fatty acid elongation";"Fatty acid degradation";"Toluene degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Androstenedione degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"2-methylpropene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Lysine degradation";"Methyl ketone biosynthesis (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Tryptophan metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Pyruvate fermentation to butanol II (engineered)";"Benzoyl-coa degradation I (aerobic)";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Geraniol degradation";"Lysine degradation";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Fermentation to 2-methylbutanoate";"Propanoate metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Caprolactam degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Phenylalanine metabolism";"Caprolactam degradation";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Acyl chain remodeling of CL";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Geraniol degradation";"Fatty acid salvage"
XP_035725176.1	12	KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343	"Glycerolipid metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I"
XP_035730230.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035729598.1	12	MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683	"Sulfite oxidation III";"Selenocompound metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Selenate reduction";"Purine metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III"
XP_035741937.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_035741225.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_035728917.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035721710.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035723001.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_035734103.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_035729711.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035739569.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_035738271.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035734952.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035718733.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035737563.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_035736209.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035727122.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8051	"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I"
XP_035720296.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035742046.1	4	MetaCyc: PWY-6517;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59	"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_035717692.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035735746.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035725662.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035734309.1	17	MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_035728057.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035723729.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035719990.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_035735720.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035742020.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_035739085.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035738670.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_035736843.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035732680.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_035722990.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_035734630.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA"
XP_035720311.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035734012.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_035744143.1	11	MetaCyc: PWY-5659;MetaCyc: PWY-7456;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-882;KEGG: 00051+5.3.1.8	"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism"
XP_035725723.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035724475.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035718412.1	3	KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17	"Purine metabolism";"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism"
XP_035732728.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_035735785.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_035726169.1	13	Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-2201	"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Folate transformations I"
XP_035718796.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035717968.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035724310.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_035718519.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;MetaCyc: PWY-4661;Reactome: R-HSA-1855204;MetaCyc: PWY-6554;MetaCyc: PWY-6365	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"
XP_035731539.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035719933.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_035739514.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate"
XP_035738162.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035734980.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035718255.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035723007.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_035724690.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035731568.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_035734237.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035718242.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035723225.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_035733179.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035740777.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035742605.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035720515.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035720658.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_035720107.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035741245.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035739754.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_035720742.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035721599.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_035739708.1	5	KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;MetaCyc: PWY-7782	"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis"
XP_035732000.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_035743889.1	8	MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_035734164.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_035724106.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035729888.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035732575.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035743892.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035736970.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035718878.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5358749	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated"
XP_035725017.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738585.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_035730079.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_035743550.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_035741931.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035739605.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_035727142.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035741252.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035740087.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035738561.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035728719.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_035742036.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_035742183.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035725878.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_035731822.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035737465.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035728559.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483	"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1"
XP_035738883.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035742279.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_035737916.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism"
XP_035743684.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663	"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_035742528.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_035739036.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035728703.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-2151201	"HATs acetylate histones";"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis"
XP_035728880.1	4	KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation"
XP_035728452.1	9	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035722870.1	32	Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-167242	"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_035731455.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery"
XP_035718805.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035717507.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035725412.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035720223.1	7	Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_035739678.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035736459.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_035720774.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035718998.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035743972.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_035739775.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035717766.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Hyaluronan uptake and degradation"
XP_035719105.1	33	Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746	"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein"
XP_035741927.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035727174.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035730246.1	29	Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;Reactome: R-HSA-5685942;Reactome: R-HSA-6803207;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-5693548;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;Reactome: R-HSA-5693568	"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Stabilization of p53";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Sensing of DNA Double Strand Breaks";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035731212.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_035730220.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2151201	"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis"
XP_035725519.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035718662.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035729284.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_035723509.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_035727352.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_035735948.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-210500	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_035741235.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035731060.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035723947.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_035720732.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_035723402.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035741941.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035722517.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_035731388.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035727132.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035725759.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_035736712.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035718723.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_035739877.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035718566.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035720368.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_035738262.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035731470.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035742024.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway"
XP_035735724.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035741374.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_035730218.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035718142.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_035741033.1	5	MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841	"Folate transformations I";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)"
XP_035735465.1	10	Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-9617324	"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_035722994.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_035734634.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_035732684.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_035720080.1	21	Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7219;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_035740623.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035723125.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_035727878.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035722901.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035721473.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035725527.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_035718335.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035742877.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035727255.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
XP_035720207.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035735916.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035730399.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035734264.1	24	Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-190861	"RHO GTPases Activate Formins";"Recycling pathway of L1";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly"
XP_035733183.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035724206.1	6	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_035717523.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035719031.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035722529.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)"
XP_035734672.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035724314.1	10	MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292	"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Other glycan degradation";"HS-GAG degradation";"Galactose metabolism";"MPS VII - Sly syndrome"
XP_035723180.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035728288.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035721635.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_035726424.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035735189.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_035741903.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_035736656.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035728727.1	10	MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol"
XP_035720196.1	6	MetaCyc: PWY-5497;MetaCyc: PWY-7442;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-6606	"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II"
XP_035726639.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_035724197.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035730161.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813	"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids"
XP_035729513.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035733678.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_035731923.1	9	Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695	"mTOR signalling";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Neutrophil degranulation"
XP_035725053.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035718531.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_035725677.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035728968.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035730619.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740573.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_035734849.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_035739750.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_035731695.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035736319.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_035729402.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_035719679.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035728689.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035734522.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_035729947.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035731751.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
XP_035736002.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_035724163.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035729509.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_035720339.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035743940.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035731798.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_035719066.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035743508.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035734453.1	8	KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_035726248.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_035724899.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035719832.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035721961.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035733085.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035724450.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_035722832.1	11	Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-1268020;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-5628897	"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Mitochondrial protein import";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes"
XP_035727274.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035728115.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035724882.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035718132.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_035734147.1	5	Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168	"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_035721377.1	13	Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-1660662;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-4341670;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2022857	"Neutrophil degranulation";"HS-GAG degradation";"Glycosphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Other glycan degradation";"MPS IV - Morquio syndrome B";"Defective NEU1 causes sialidosis";"Galactose metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation"
XP_035731112.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_035735395.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108	"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_035728949.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035729687.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035724856.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035723023.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035721748.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_035726872.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035727805.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035720857.1	2	Reactome: R-HSA-6809371;Reactome: R-HSA-6805567	"Formation of the cornified envelope";"Keratinization"
XP_035728884.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_035720451.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_035740258.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035725029.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035738704.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035717215.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035720498.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035737688.1	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_035718677.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035722041.1	6	MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560	"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Triglyceride catabolism"
XP_035735718.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035717445.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035729225.1	14	MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4	"Anandamide biosynthesis II";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PC";"Ether lipid metabolism";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism"
XP_035723717.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035720770.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035717559.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035744233.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_035738879.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035726781.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_035742283.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035727170.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035733514.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736801.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4	"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_035736942.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035730224.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919	"Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils"
XP_035718541.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_035735558.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035735481.1	13	KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952	"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions"
XP_035731064.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035721006.1	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035719713.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_035717486.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035743930.1	5	KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6	"Purine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism"
XP_035739283.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035741551.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035741488.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation"
XP_035722713.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_035740659.1	6	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_035729937.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035724328.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035741598.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_035733128.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035738220.1	17	MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381	"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pyruvate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Propanoate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_035736802.1	12	MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism"
XP_035738577.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035735456.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035725468.1	6	Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_035717498.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035744102.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035718449.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_035724734.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035722784.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_035718555.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035726516.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035740969.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035741586.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035734049.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_035718618.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_035718829.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035721282.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035740785.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035725853.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_035742214.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035741545.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035735850.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035733583.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_035737258.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_035736768.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_035731735.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035735482.1	13	Reactome: R-HSA-6802946;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948	"Signaling by moderate kinase activity BRAF mutants";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Signaling by high-kinase activity BRAF mutants";"Human cytomegalovirus infection";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Thermogenesis";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants"
XP_035718715.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035738965.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_035738124.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035719343.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035738810.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035736739.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_035721962.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035740173.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035725574.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035722831.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035724881.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035728813.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035739824.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_035727661.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_035742077.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035722343.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-416482	"FCERI mediated MAPK activation";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events"
XP_035727986.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035718398.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117	"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis"
XP_035724597.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035729650.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035721795.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035730700.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_035722042.1	6	MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3	"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerophospholipid metabolism"
XP_035727103.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035743657.1	4	KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;MetaCyc: PWY-4261	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Glycerol degradation I"
XP_035739444.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035743154.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035720703.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_035742110.1	9	MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18	"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism"
XP_035737659.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_035739077.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_035728809.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_035728515.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_035734909.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730277.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_035723088.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_035718532.1	2	Reactome: R-HSA-3785653;Reactome: R-HSA-3322077	"Myoclonic epilepsy of Lafora";"Glycogen synthesis"
XP_035734547.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7858	"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II"
XP_035740736.1	17	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-167246	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Th1 and Th2 cell differentiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript"
XP_035731864.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035731786.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_035724744.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_035743800.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_035736001.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_035730495.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035737995.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_035722217.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035731752.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
XP_035734039.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_035731745.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035729584.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035729401.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_035728604.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_035733062.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035724910.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176408	"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase"
XP_035738666.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_035741535.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_035729494.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035727570.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_035732330.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035722153.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035742434.1	7	MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism"
XP_035718141.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035719333.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035730670.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_035721324.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_035738261.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035736681.1	4	MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_035727005.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035722333.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_035726904.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035720673.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035743175.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_035717159.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035732609.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_035723823.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035719153.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377	"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins"
XP_035719902.1	4	MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_035741423.1	6	MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism"
XP_035734068.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_035722827.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_035734325.1	6	KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25	"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism"
XP_035722610.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_035740948.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035739434.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_035741843.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_035733885.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035718624.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-8854214	"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs"
XP_035718127.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035734671.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035736415.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_035742579.1	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_035717196.1	12	Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035740075.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_035729015.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_035719610.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_035723157.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035719827.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_035723608.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_035727935.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035722421.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035743367.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_035726195.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035738224.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-6722;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679	"Carnitine metabolism";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Propanoate metabolism";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis"
XP_035727219.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035734733.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035725646.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035735762.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events"
XP_035729360.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035743092.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035743971.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035725817.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035740724.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_035728770.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_035725411.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035722780.1	17	Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110314	"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_035724730.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035729088.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035721977.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_035721361.1	1	Reactome: R-HSA-419771	"Opsins"
XP_035722819.1	39	Reactome: R-HSA-6811558;Reactome: R-HSA-5654221;Reactome: R-HSA-5654720;Reactome: R-HSA-5654704;Reactome: R-HSA-5654219;Reactome: R-HSA-5654712;Reactome: R-HSA-5654699;Reactome: R-HSA-5654719;Reactome: R-HSA-5655253;Reactome: R-HSA-5654732;Reactome: R-HSA-5654228;Reactome: R-HSA-190373;Reactome: R-HSA-5654693;Reactome: R-HSA-5654688;Reactome: R-HSA-5658623;Reactome: R-HSA-2219530;Reactome: R-HSA-5654733;Reactome: R-HSA-5654726;Reactome: R-HSA-190371;Reactome: R-HSA-109704;Reactome: R-HSA-5654710;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-5654687;Reactome: R-HSA-2033514;Reactome: R-HSA-2033519;Reactome: R-HSA-5655302;Reactome: R-HSA-5654227;Reactome: R-HSA-5654727;Reactome: R-HSA-5654689;Reactome: R-HSA-1257604;Reactome: R-HSA-1839122;Reactome: R-HSA-190322;Reactome: R-HSA-190375;Reactome: R-HSA-8853338;Reactome: R-HSA-1839130;Reactome: R-HSA-190372;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade: FGFR1";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR2";"SHC-mediated cascade:FGFR4";"Signaling by FGFR2 in disease";"Negative regulation of FGFR3 signaling";"Phospholipase C-mediated cascade, FGFR4";"FGFR1c ligand binding and activation";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR1";"FGFRL1 modulation of FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR1 signaling";"FGFR3b ligand binding and activation";"PI3K Cascade";"PI-3K cascade:FGFR3";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"Downstream signaling of activated FGFR1";"FGFR3 mutant receptor activation";"Activated point mutants of FGFR2";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade, FGFR3";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR1";"PIP3 activates AKT signaling";"Signaling by activated point mutants of FGFR1";"FGFR4 ligand binding and activation";"FGFR2c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"Signaling by activated point mutants of FGFR3";"FGFR3c ligand binding and activation";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade"
XP_035740192.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035741942.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035731139.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035723401.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_035739397.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035727131.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035743254.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_035727398.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_035720731.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_035718661.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035735854.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035727351.1	15	Reactome: R-HSA-176034;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167200	"Interactions of Tat with host cellular proteins";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_035733228.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035729823.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035738814.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035727829.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_035742426.1	7	MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_035725570.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035743613.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis"
XP_035721336.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035727715.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_035721565.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_035731168.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946	"RAF activation";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants"
XP_035738562.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035731427.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035739846.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035738185.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035728498.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035720766.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_035732175.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035724767.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035744098.1	8	KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;MetaCyc: PWY-2301;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6580	"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_035728451.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035728588.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035731616.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035739440.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035721199.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035726026.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035742114.1	9	Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533	"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Gliotoxin biosynthesis"
XP_035724928.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035725935.1	7	Reactome: R-HSA-212436;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035720507.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035724506.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035720949.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035729705.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_035727166.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-9609690	"RHO GTPases Activate Formins";"Recycling pathway of L1";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Gap junction assembly";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"HCMV Early Events"
XP_035727449.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035742846.1	4	Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-210991	"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions"
XP_035717774.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_035741974.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035727127.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035727624.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944	"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2"
XP_035738828.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_035734743.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035733214.1	52	Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-1834949;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic sensors of pathogen-associated DNA";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_035734957.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_035738161.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035731860.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035718935.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation"
XP_035724726.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035733306.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035743275.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035724740.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_035719253.1	6	MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_035739128.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035724379.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035741932.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035727141.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035727853.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035741251.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035739493.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_035718227.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035735316.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035738603.1	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_035743497.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_035717296.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_035728159.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_035724914.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035723257.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_035718005.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035729490.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035720741.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035732334.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035717755.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_035743779.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_035725119.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941	"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses"
XP_035729778.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_035736903.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035720312.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035738218.1	17	MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;Reactome: R-HSA-163765;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Carnitine metabolism";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Biotin transport and metabolism"
XP_035738356.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035732108.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035731323.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035740615.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035722505.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035738083.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035725661.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_035717691.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_035725103.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035730010.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202	"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition"
XP_035732372.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035737348.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_035720288.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035740558.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035718620.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_035717515.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730632.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035723109.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035733444.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035726030.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035735100.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade"
XP_035720939.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035727439.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035740887.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035738399.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_035729347.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035728207.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183	"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_035725945.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_035721587.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_035741257.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035742867.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035732318.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035719268.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_035740734.1	17	Reactome: R-HSA-113418;Reactome: R-HSA-674695;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167246;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167152;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167242	"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"T cell receptor signaling pathway";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Th1 and Th2 cell differentiation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_035723303.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035723298.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_035724746.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_035734662.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_035725309.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_035731866.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035723932.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035721804.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035721858.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_035742461.1	10	MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_035739148.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_035723251.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035727453.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035724720.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_035721275.1	11	Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035722638.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035734998.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase"
XP_035740772.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_035724688.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035727121.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I"
XP_035735310.1	24	Reactome: R-HSA-202424;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-2871837;KEGG: 04926+2.7.11.1	"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"Integrin signaling";"RHO GTPases activate PKNs";"Activation of AKT2";"FCERI mediated NF-kB activation";"Relaxin signaling pathway"
XP_035729712.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_035731460.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery"
XP_035720378.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035734951.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_035738272.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035718247.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035719307.1	3	Reactome: R-HSA-4086400;Reactome: R-HSA-4608870;Reactome: R-HSA-373080	"PCP/CE pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)"
XP_035736284.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_035723002.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_035738167.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035729496.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_035735475.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_035732299.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_035737856.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_035742148.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035722735.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_035727868.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035741650.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_035721326.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035741109.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035733238.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035725693.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_035728353.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035742436.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_035721340.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035718811.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035726906.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035728294.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035736964.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_035717722.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_035731343.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735690.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035739830.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_035741113.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035734017.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_035719988.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035733765.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035728045.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035739436.1	11	Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-8862803;Reactome: R-HSA-2871796;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FCERI mediated MAPK activation";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression"
XP_035733668.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856	"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling"
XP_035717233.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035736180.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035719239.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035728978.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035725667.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035743346.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_035740563.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035738838.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_035735454.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_035736717.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035725626.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035719786.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035734878.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_035735408.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035717413.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035721393.1	3	Reactome: R-HSA-5673001;Reactome: R-HSA-167044;Reactome: R-HSA-4420097	"RAF/MAP kinase cascade";"Signalling to RAS";"VEGFA-VEGFR2 Pathway"
XP_035727137.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035723955.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035727634.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897	"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes"
XP_035721208.1	7	MetaCyc: PWY-6470;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-5265	"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)"
XP_035723942.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_035720737.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457	"Ca2+ pathway";"Rap1 signalling";"cGMP effects"
XP_035732806.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035741584.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035739138.1	11	KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545	"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_035722419.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035720305.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035727357.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035724736.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035718667.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035731390.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035722786.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_035731217.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035742304.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035740910.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_035726605.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035737081.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035743977.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_035719752.1	12	MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Methane metabolism"
XP_035721092.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035737979.1	9	KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation"
XP_035727264.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035738095.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_035721367.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_035717502.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035733418.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035731153.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism"
XP_035725576.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035733834.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_035739595.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_035733248.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_035727849.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035731074.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035738126.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035739485.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors"
XP_035742611.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_035720501.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_035729331.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs"
XP_035718313.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035721150.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_035720484.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035728851.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035728143.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events"
XP_035727984.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035721609.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035737601.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154	"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin"
XP_035731447.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_035741015.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_035733872.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035722249.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_035739169.1	6	KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_035739446.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035730622.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035734759.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_035739420.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_035720760.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035736023.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035726046.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383	"Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_035717243.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035726020.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_035740082.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035718309.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035730526.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035740730.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035725634.1	15	Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-113418	"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex"
XP_035736007.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035739781.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035721783.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035741209.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035733138.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035741976.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035727626.1	16	Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408	"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_035731803.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_035734270.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497	"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Cilium Assembly";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_035729942.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035730908.1	6	MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336	"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_035729407.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035733391.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_035719211.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035733304.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035727811.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035718839.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035735314.1	24	Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"RSK activation";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"mTOR signaling pathway";"RHO GTPases activate PKNs";"Integrin signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_035731628.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035730271.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_035736937.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035722139.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
YP_009915668.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035724916.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035731725.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035726018.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035724192.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035728722.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_035717294.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035736729.1	5	KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527	"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism";"Stachyose degradation"
XP_035741608.1	7	Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system"
XP_035734053.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_035726963.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035741654.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_035738293.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740793.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035732336.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035734386.1	4	MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_035721344.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035725849.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_035728290.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035723198.1	18	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035736815.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_035738354.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_035744115.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035733595.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_035739248.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation"
XP_035738308.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_035727221.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035735163.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035731578.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035718147.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_035734132.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035736184.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035738267.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035726997.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035736376.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_035733446.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035742834.1	32	Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery"
XP_035734352.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035720098.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035727012.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_035735450.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8	"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism"
XP_035739300.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035736513.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_035729932.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035740726.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_035738226.1	17	Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2	"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Propanoate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes"
XP_035733893.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_035727630.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519	"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression"
XP_035725644.1	15	Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242	"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_035718429.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_035737297.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_035723552.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_035722860.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154	"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin"
XP_035721250.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Macroautophagy"
XP_035720533.1	3	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation"
XP_035731301.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_035718160.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159236	"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035737633.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035739639.1	13	Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Signaling by PDGF";"Extracellular matrix organization";"Anchoring fibril formation";"Laminin interactions";"ECM proteoglycans";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Collagen degradation"
XP_035732458.1	6	Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035732581.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035733461.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035742300.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035722149.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035739269.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035732404.1	9	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"MAP2K and MAPK activation"
XP_035736947.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035743256.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_035740914.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035724395.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035725868.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_035727260.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035729319.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738144.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035727693.1	18	Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-6783984;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00020+1.8.1.4	"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glycine, serine and threonine metabolism";"Lysine catabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation";"Citrate cycle (TCA cycle)"
XP_035718672.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-6683;MetaCyc: PWY-5340	"Selenocompound metabolism";"Sulfite oxidation III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Monobactam biosynthesis";"Purine metabolism";"Sulfur metabolism";"Selenate reduction";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation"
XP_035725839.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035719323.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Cilium Assembly";"Gap junction assembly";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_035721334.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035724615.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_035732320.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_035744009.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035738816.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035743651.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035742668.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_035721108.1	20	Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210	"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_035721657.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035727980.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_035726877.1	29	Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-6782210	"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_035735065.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035728502.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_035739116.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035743795.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035739071.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035731117.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_035718137.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035721372.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_035731614.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035742989.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035734335.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_035722837.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_035724887.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035741778.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_035720764.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268	"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_035739668.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483	"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs"
XP_035739424.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_035727667.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_035724504.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen degradation"
XP_035720425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035724481.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035724558.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035727925.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035742238.1	8	Reactome: R-HSA-163754;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;MetaCyc: PWY-1861	"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_035737106.1	11	Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455	"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism"
XP_035722431.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation"
XP_035717776.1	4	Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane"
XP_035726024.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035734155.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_035742116.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_035735771.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167290	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation"
XP_035738410.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_035719551.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_035740660.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_035737016.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_035725886.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis"
XP_035732195.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_035723568.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035724438.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation"
XP_035724773.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035729064.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751	"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated"
XP_035725845.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_035736725.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_035717122.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035732462.1	6	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"ESR-mediated signaling"
XP_035733582.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_035736628.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035725590.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035717560.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035744119.1	3	Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035734770.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823	"Regulation of PTEN localization";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex"
XP_035725852.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_035741553.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035721283.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035740230.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_035725480.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_035733716.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035740267.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035728812.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035735048.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035722135.1	7	MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367	"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_035722342.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-114604	"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade"
XP_035744266.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035738767.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377	"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins"
XP_035719342.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035738928.1	16	Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-1042;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723	"Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Rubisco shunt"
XP_035741041.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035739377.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-73762;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"RNA Polymerase I Transcription Initiation";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling"
XP_035722355.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_035726344.1	10	KEGG: 04660+2.7.10.2;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5357905	"T cell receptor signaling pathway";"Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TNFR1 signaling"
XP_035734857.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035730856.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035731729.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035720868.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_035740172.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035742645.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035724814.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint"
XP_035739652.1	9	KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism"
XP_035720147.1	13	Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764	"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling"
XP_035732040.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_035720702.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_035739748.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-111465	"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins"
XP_035732026.1	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_035724469.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_035721997.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035722043.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6118;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3	"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophospholipid metabolism"
XP_035736229.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_035718051.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_035727102.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035738793.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_035739946.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035741066.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035742985.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_035734159.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035724448.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_035744241.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_035718533.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_035731921.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035727929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035720429.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035734600.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_035724619.1	12	MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108	"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V"
XP_035732093.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_035720849.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035744005.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035742946.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_035737797.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035728957.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035728405.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-1855204	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_035735676.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035719090.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035724828.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism"
XP_035725835.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035730197.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035743799.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035729798.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035743516.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-4420097	"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"p38MAPK events";"DSCAM interactions";"VEGFA-VEGFR2 Pathway"
XP_035738740.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035727594.1	11	Reactome: R-HSA-114604;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-9008059;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-912694;Reactome: R-HSA-512988	"GPVI-mediated activation cascade";"PD-1 signaling";"Platelet sensitization by LDL";"Interleukin-37 signaling";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Signal regulatory protein family interactions";"PECAM1 interactions";"Regulation of IFNA signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_035731753.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_035723060.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_035722332.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-174411	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere"
XP_035732548.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035718845.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035729470.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_035735271.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035723037.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035719903.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_035741422.1	6	KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_035726657.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035723822.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035717276.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035722145.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035735038.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035721877.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_035717909.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035720672.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035722152.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035721471.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_035722903.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035725917.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035740621.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035719145.1	12	MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_035719332.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035740375.1	7	Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-166208	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling"
XP_035741529.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_035733918.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035743295.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_035717521.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035719919.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035735954.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_035723549.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_035724136.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_035718886.1	4	MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14	"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism"
XP_035724218.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035723907.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035741842.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_035734368.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035729876.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_035724356.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785	"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of DVL";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome"
XP_035727305.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_035736614.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035739097.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_035723511.1	3	Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_035736866.1	19	Reactome: R-HSA-525793;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663213	"Myogenesis";"Rho GTPase cycle";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs"
XP_035740167.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035720221.1	7	KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation"
XP_035725760.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_035740664.1	6	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_035740428.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035717790.1	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_035736784.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035744166.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035735622.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins"
XP_035718102.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035735763.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035729212.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035725929.1	42	Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-5625886;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-9610379;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-212300;Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-977225;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519	"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Late Events";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"PRC2 methylates histones and DNA";"HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Amyloid fiber formation";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"RMTs methylate histone arginines";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression"
XP_035734732.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035733946.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035743093.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_035719235.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_035727098.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035741105.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035732756.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_035737387.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041	"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle"
XP_035720576.1	7	KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation"
XP_035742362.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035717812.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_035738734.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035721061.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035736460.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_035717564.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035718721.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035725594.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_035734774.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757	"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation"
XP_035729388.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_035740234.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_035741943.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035737038.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035717733.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_035738563.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035724416.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035733265.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035722739.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_035729822.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035741870.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035723470.1	6	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-201722	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex"
XP_035732295.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035735479.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035742918.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035737526.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035736055.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_035732044.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035724965.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_035741476.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035726779.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723876.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035738881.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035729442.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035717222.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035730408.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_035743900.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_035725737.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_035735016.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035734755.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035739556.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_035727886.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035726208.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_035719252.1	6	Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_035724079.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_035739165.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_035728521.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_035720667.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_035730106.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035724981.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035720164.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035718305.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035738865.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035741003.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035734604.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035737567.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling"
XP_035724666.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_035738910.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035734742.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035718737.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035733281.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035739489.1	16	Reactome: R-HSA-5603037;Reactome: R-HSA-5603041;Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-5602498;Reactome: R-HSA-1236974;Reactome: R-HSA-975110;Reactome: R-HSA-975138;Reactome: R-HSA-975155;Reactome: R-HSA-166058;Reactome: R-HSA-5602680;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-209543;Reactome: R-HSA-9020702	"IRAK4 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 deficiency (TLR2/4)";"ER-Phagosome pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 dependent cascade initiated on endosome";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"p75NTR recruits signalling complexes";"Interleukin-1 signaling"
XP_035742556.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035742165.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_035727845.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035721605.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035727852.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035741933.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035722094.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_035727480.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_035720980.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_035738602.1	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_035723064.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035733006.1	13	KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883	"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II"
XP_035736217.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_035739492.1	16	Reactome: R-HSA-5602498;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-5603037;Reactome: R-HSA-3134963;Reactome: R-HSA-975871;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-166058;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680	"MyD88 deficiency (TLR2/4)";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)"
XP_035725378.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035726609.1	5	Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035730263.1	6	Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-162594	"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_035732904.1	7	MetaCyc: PWY-7841;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_035740869.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035736447.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035738082.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035736333.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236974	"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Degradation of DVL";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway"
XP_035731322.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035738099.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035720260.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035725721.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035718594.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035744141.1	4	Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801	"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
XP_035736902.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035720313.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035743040.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_035737975.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_035718501.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035737530.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035735950.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_035721020.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035722370.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035726613.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_035734311.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035730297.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035720309.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035744127.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035725747.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis"
XP_035725102.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035732373.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035730633.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035736827.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035733652.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_035736610.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035734663.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_035741064.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_035727452.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035720103.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005	"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport"
XP_035723933.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035740438.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035727880.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035720231.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_035739550.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_035739944.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035732179.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035743708.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_035719225.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_035731598.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035733930.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_035725939.1	7	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-212436	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway"
XP_035723302.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035736211.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035738465.1	26	Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-8866654;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-1362277;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-69205;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-6804114;Reactome: R-HSA-5655862;Reactome: R-HSA-4615885;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-174417	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Translesion synthesis by POLI";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Transcription of E2F targets under negative control by DREAM complex";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"G1/S-Specific Transcription";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLK";"SUMOylation of DNA replication proteins";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis"
XP_035723003.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript"
XP_035735674.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035723178.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035728270.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035732018.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035719937.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_035727825.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035742944.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_035722280.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_035742550.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022692	"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity"
XP_035740773.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_035734697.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_035736139.1	4	MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Selenocompound metabolism"
XP_035737561.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_035718731.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035720986.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_035734101.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_035721569.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_035723990.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_035731135.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_035733680.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035717274.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035725689.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_035736427.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_035719729.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_035722815.1	39	Reactome: R-HSA-5654719;Reactome: R-HSA-5655253;Reactome: R-HSA-5654732;Reactome: R-HSA-5654704;Reactome: R-HSA-5654720;Reactome: R-HSA-5654219;Reactome: R-HSA-5654712;Reactome: R-HSA-5654699;Reactome: R-HSA-5654221;Reactome: R-HSA-6811558;Reactome: R-HSA-190371;Reactome: R-HSA-190373;Reactome: R-HSA-5654688;Reactome: R-HSA-5658623;Reactome: R-HSA-5654693;Reactome: R-HSA-2219530;Reactome: R-HSA-5654733;Reactome: R-HSA-5654726;Reactome: R-HSA-5654228;Reactome: R-HSA-5654689;Reactome: R-HSA-5654727;Reactome: R-HSA-1257604;Reactome: R-HSA-5655302;Reactome: R-HSA-5654227;Reactome: R-HSA-5654687;Reactome: R-HSA-5654700;Reactome: R-HSA-2033514;Reactome: R-HSA-2033519;Reactome: R-HSA-109704;Reactome: R-HSA-5654710;Reactome: R-HSA-5654695;Reactome: R-HSA-5673001;Reactome: R-HSA-8853338;Reactome: R-HSA-190375;Reactome: R-HSA-1839130;Reactome: R-HSA-190372;Reactome: R-HSA-5654706;Reactome: R-HSA-1839122;Reactome: R-HSA-190322	"SHC-mediated cascade:FGFR4";"Signaling by FGFR2 in disease";"Negative regulation of FGFR3 signaling";"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR4";"Phospholipase C-mediated cascade: FGFR1";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR2";"Phospholipase C-mediated cascade, FGFR2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FGFR3b ligand binding and activation";"FGFR1c ligand binding and activation";"SHC-mediated cascade:FGFR1";"FGFRL1 modulation of FGFR1 signaling";"FRS-mediated FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR1 signaling";"Phospholipase C-mediated cascade, FGFR4";"PI-3K cascade:FGFR1";"Negative regulation of FGFR2 signaling";"PIP3 activates AKT signaling";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade, FGFR3";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR2 signaling";"FGFR3 mutant receptor activation";"Activated point mutants of FGFR2";"PI3K Cascade";"PI-3K cascade:FGFR3";"PI-3K cascade:FGFR2";"RAF/MAP kinase cascade";"Signaling by FGFR3 point mutants in cancer";"FGFR2c ligand binding and activation";"Signaling by activated point mutants of FGFR3";"FGFR3c ligand binding and activation";"FRS-mediated FGFR3 signaling";"Signaling by activated point mutants of FGFR1";"FGFR4 ligand binding and activation"
XP_035722960.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035731342.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035724172.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035743046.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_035719815.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_035733993.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035719960.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_035744121.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035730258.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035728352.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035730204.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919	"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils"
XP_035741959.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_035718884.1	6	Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"Neddylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035728053.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_035732997.1	19	MetaCyc: PWY-6545;Reactome: R-HSA-380320;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_035718766.1	4	MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_035737536.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_035735956.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_035727215.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035740562.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035726199.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling"
XP_035721026.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_035724134.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_035717998.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035726182.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035744147.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_035741996.1	7	KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;MetaCyc: PWY-3561	"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Choline biosynthesis III"
XP_035741112.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035736616.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035743085.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035724308.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035718507.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_035719513.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035735791.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_035717519.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035742091.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_035725884.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725	"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_035723943.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_035732510.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_035735642.1	28	Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-3371453;Reactome: R-HSA-68962;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"Termination of translesion DNA synthesis";"Meiotic recombination";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Regulation of HSF1-mediated heat shock response";"Activation of the pre-replicative complex";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_035717412.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035733940.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035718727.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035723105.1	7	Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456	"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation"
XP_035722921.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_035721392.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_035720935.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035717759.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_035720227.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035723517.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035740161.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035739058.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035729066.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348	"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex"
XP_035717503.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035718741.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035731090.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_035740619.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035734243.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035730573.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_035741511.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035718692.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035726458.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035741923.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_035726581.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_035728142.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378	"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling"
XP_035718312.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035727188.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035744264.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035720685.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569	"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"HCMV Early Events";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_035724621.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035731332.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035737585.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_035724375.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035717878.1	13	Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_035738887.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_035730854.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_035718009.1	9	KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-1042	"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)"
XP_035741876.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035726320.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546	"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling"
XP_035731152.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_035743036.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_035725731.1	10	MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7922;MetaCyc: PWY-7661;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;Reactome: R-HSA-913709	"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation of mucins"
XP_035739684.1	6	Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788	"Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling"
XP_035726346.1	10	KEGG: 04660+2.7.10.2;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5357905	"T cell receptor signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"TNFR1-induced NFkappaB signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TNFR1 signaling"
XP_035723870.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035741470.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035720620.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035721612.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035724816.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation"
XP_035721030.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035740083.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035737277.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035738615.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_035717242.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035743279.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_035743906.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_035733873.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736837.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_035718013.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_035740218.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_035736022.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035718939.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035731919.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035721516.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-73930	"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_035728998.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035717174.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035726256.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035735014.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035721799.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035735381.1	42	Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-2559586;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-212300;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-3214847	"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"DNA Damage/Telomere Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"Estrogen-dependent gene expression";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Opening";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"PRC2 methylates histones and DNA";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"HATs acetylate histones"
XP_035737791.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035728951.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035727884.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035724167.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035721782.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_035734606.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035730191.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035740285.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_035743750.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_035729943.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035726318.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6783310	"Neutrophil degranulation";"Fanconi Anemia Pathway"
XP_035733934.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_035731802.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_035738785.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035732775.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035730104.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035720449.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035724193.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035731768.1	7	Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035736735.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9029569	"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_035723679.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035735670.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035717345.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_035736307.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_035727115.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_035742508.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035720618.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035738969.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_035742940.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_035722284.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_035742554.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035733004.1	19	MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6	"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism"
XP_035725673.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035738746.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035741212.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035740577.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)"
XP_035719284.1	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
XP_035740220.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_035736638.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035733091.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035722096.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_035717527.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035740789.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035733187.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035738289.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035732906.1	7	MetaCyc: PWY-5129;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836	"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis"
XP_035735495.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_035722964.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035734052.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_035720398.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035731739.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035726962.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035738292.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035719125.1	3	MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581	"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_035718719.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035721295.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_035738938.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_035718596.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035734978.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035741549.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035740792.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-164944;Reactome: R-HSA-4420097;Reactome: R-HSA-8849471	"Regulation of actin dynamics for phagocytic cup formation";"Nef and signal transduction";"VEGFA-VEGFR2 Pathway";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_035720219.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035717541.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035718880.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-196299	"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade"
XP_035728170.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035734353.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035743471.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035721871.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_035737879.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_035724130.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_035740810.1	18	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_035725911.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_035738008.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035718559.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035740965.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035734294.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_035734133.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035735162.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035741037.1	5	MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate"
XP_035730348.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_035727288.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035744164.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_035725880.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_035723553.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035719717.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035734329.1	6	KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52	"Methane metabolism";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_035737632.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035740666.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035735883.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_035733944.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035729933.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035720439.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035743018.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_035727013.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_035740079.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035723713.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_035717335.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035724838.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035722888.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035736745.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_035732754.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_035735561.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_035725719.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035736752.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740118.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035722557.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_035738736.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035739575.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_035717566.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035727009.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway"
XP_035732085.1	9	MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Pyruvate metabolism";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_035737999.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035730499.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035723027.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035738948.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_035741539.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_035738500.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_035743997.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_035718057.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions"
XP_035723205.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035731749.1	6	Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36	"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_035724414.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_035739680.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism"
XP_035741474.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_035723874.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035725215.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_035735536.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_035724140.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_035720468.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035740261.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035727968.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-532668;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-349425	"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Degradation of DVL";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_035728519.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_035737524.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035734905.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035734457.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035734851.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Regulation of RAS by GAPs";"Degradation of DVL";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_035741047.1	17	MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methylaspartate cycle";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_035739967.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035734898.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035728412.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_035727107.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035722778.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-69166	"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate"
XP_035726473.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035727604.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035739334.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_035738808.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035721989.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035741022.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-69166	"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate"
XP_035727691.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_035743077.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035735438.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035731682.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035729505.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035720335.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035739073.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035737079.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035721238.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection"
XP_035718080.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035728685.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035743444.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_035734886.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035721424.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035740177.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035740674.1	6	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_035744011.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035742334.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_035719347.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_035723042.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_035737118.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane"
XP_035730615.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035724593.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_035735224.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_035728817.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER"
XP_035724483.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035737236.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_035742108.1	9	MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis"
XP_035723784.1	12	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Signaling by FGFR1 in disease";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"NRAGE signals death through JNK"
XP_035733891.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_035722896.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035725857.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_035727259.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035718196.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035730395.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_035741466.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035736511.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035726769.1	10	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035732861.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_035718912.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035729253.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035729394.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035717127.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035721639.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation"
XP_035737631.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035717624.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035724048.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_035731303.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_035739250.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041	"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle"
XP_035719580.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035731002.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_035743214.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification"
XP_035727296.1	17	Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Human papillomavirus infection";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"Meiotic synapsis";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Fanconi Anemia Pathway";"mTOR signaling pathway";"Processing of DNA double-strand break ends"
XP_035718600.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035738573.1	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
XP_035740956.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035731974.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_035736751.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035732583.1	9	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_035733275.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035723129.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_035718339.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035717853.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_035722580.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_035728266.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_035717715.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035738204.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035738258.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035735448.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035734098.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035740791.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035738291.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035734051.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_035722823.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035740642.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_035725600.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_035723841.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035719823.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035732846.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035723074.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_035732617.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-211976	"PPARA activates gene expression";"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"Endogenous sterols"
XP_035732820.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035742344.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035719337.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035725912.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_035726645.1	10	KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_035722157.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035722608.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035725196.1	10	Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_035717166.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_035717449.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035743472.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035720677.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035741168.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035721872.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_035723610.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_035723827.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035738875.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035723032.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035722337.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_035732885.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035722360.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035731942.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035731801.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_035727809.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035719088.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_035742406.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_035733254.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_035721781.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_035731894.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035730916.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035730192.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035741359.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035735382.1	6	MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6787450	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion"
XP_035737792.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035719213.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730189.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035728952.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035733393.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_035724038.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_035725368.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035733092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730273.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_035728986.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035724895.1	6	Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-6922	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis"
XP_035722209.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035734543.1	20	MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-5136	"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_035730724.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035733367.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042	"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle"
XP_035721418.1	1	Reactome: R-HSA-2408557	"Selenocysteine synthesis"
XP_035741211.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_035743818.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035727813.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035723217.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_035724954.1	14	MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_035724540.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035742800.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_035720270.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035733089.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035737627.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035735218.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035717131.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_035719209.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035725080.1	42	MetaCyc: PWY-5109;MetaCyc: PWY-7656;MetaCyc: PWY-5177;MetaCyc: PWY-7401;MetaCyc: PWY-7778;KEGG: 00640+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7726;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00410+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-5136;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-7216;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606	"Fermentation to 2-methylbutanoate";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Propanoate metabolism";"Lysine degradation";"Androstenedione degradation";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"beta-Alanine metabolism";"Tryptophan metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Fatty acid elongation";"Toluene degradation";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Fatty acid salvage";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_035724763.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035731198.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035725732.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035729074.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_035741249.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035730500.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_035721595.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_035743426.1	12	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"G alpha (q) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035717227.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035720759.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035721826.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035743440.1	8	MetaCyc: PWY-7199;MetaCyc: PWY-6556;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine metabolism"
XP_035728853.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035728141.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (s) signalling events"
XP_035721840.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943	"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_035718311.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035732579.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035738589.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_035724622.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035733344.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035720503.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035731331.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035742613.1	20	Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110314	"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_035743617.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_035721420.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035740670.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035718259.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035742330.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-381038	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes"
XP_035721446.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_035729610.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_035719015.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_035735220.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035737828.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035742609.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035717241.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035731423.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370	"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Galactose catabolism"
XP_035735577.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_035728468.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_035742150.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035723578.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_035721611.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035728127.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333	"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035727207.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_035722922.1	9	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035735789.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_035721391.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_035717411.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035733800.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035724479.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035721304.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_035743062.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_035718515.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035721216.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035731535.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035735641.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_035721138.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)"
XP_035743397.1	12	MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5856;KEGG: 00130+2.1.1.222+2.1.1.64	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_035723803.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398	"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway"
XP_035735792.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_035741512.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_035740277.1	52	Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73772	"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape"
XP_035718691.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035740520.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_035719401.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035725813.1	5	MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome"
XP_035730736.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035718742.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035734737.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035718604.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035727368.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035738777.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035717788.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035718107.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035729217.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035735627.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035737218.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035717685.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_035722494.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_035733406.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035723464.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_035737136.1	5	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_035740162.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035741239.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5610787	"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state"
XP_035718813.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035728351.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035725691.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_035725658.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035725604.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035735666.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035744122.1	3	Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035721830.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035727349.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167200	"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_035740883.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035728131.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_035731341.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035719113.1	10	MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-5497;Reactome: R-HSA-196757	"L-histidine degradation III";"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines"
XP_035724171.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035729437.1	10	Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091	"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells"
XP_035742779.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035732824.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035735079.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA"
XP_035721436.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035742340.1	19	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-8876725;Reactome: R-HSA-975957;Reactome: R-HSA-3214858	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Protein methylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines"
XP_035730173.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035736455.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_035722650.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035742326.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes"
XP_035726181.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_035741111.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035730008.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events"
XP_035732077.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism"
XP_035719650.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035731327.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_035723614.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6798695;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Neutrophil degranulation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_035735236.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035719109.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168333	"snRNP Assembly";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_035739779.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035732306.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035725259.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_035739497.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_035718774.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035738158.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035738607.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_035723301.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035731890.1	9	Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801	"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD"
XP_035741638.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035744049.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035727857.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035723253.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035727451.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035734378.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420	"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi"
XP_035742463.1	10	KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis"
XP_035739804.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_035726097.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035717636.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035731459.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation"
XP_035719364.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_035731545.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035729784.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035743493.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_035720998.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_035727498.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_035737562.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_035734747.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035718732.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_035734953.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_035729460.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035734102.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_035743128.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035742587.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035721867.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_035728715.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_035739275.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_035717266.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035724544.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035737146.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_035742804.1	13	Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-8856828	"WNT5A-dependent internalization of FZD4";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis"
XP_035731586.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035737814.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035728829.1	4	MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202	"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_035736901.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035739320.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035736842.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035735660.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035718502.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035738979.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035728264.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035739346.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035744142.1	4	KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801	"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion"
XP_035734939.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035726187.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_035725722.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035734013.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_035727329.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035725663.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids"
XP_035738081.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035723111.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035731321.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035729323.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813	"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids"
XP_035724010.1	4	Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583	"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_035731675.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035732844.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035725697.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_035722656.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035739385.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035717164.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_035732668.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035723988.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_035721430.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035733698.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_035731347.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723239.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035718413.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_035737838.1	17	MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217	"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Purine salvage"
XP_035735230.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035731433.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_035730914.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035731896.1	15	Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_035734741.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035722298.1	5	MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)"
XP_035721861.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_035744029.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035733256.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_035742404.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035719251.1	6	MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_035743867.1	13	MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7102	"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_035721467.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_035717630.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035719298.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035727035.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035731525.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035738163.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035733299.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035723307.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035717260.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_035739491.1	16	Reactome: R-HSA-5602680;Reactome: R-HSA-1257604;Reactome: R-HSA-166058;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-975138;Reactome: R-HSA-975155;Reactome: R-HSA-1236974;Reactome: R-HSA-5602498	"MyD88 deficiency (TLR5)";"PIP3 activates AKT signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 dependent cascade initiated on endosome";"ER-Phagosome pathway";"MyD88 deficiency (TLR2/4)"
XP_035735308.1	24	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-9634635;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;Reactome: R-HSA-202424	"Relaxin signaling pathway";"RHO GTPases activate PKNs";"Integrin signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"Thermogenesis";"GPVI-mediated activation cascade";"mTOR signaling pathway";"Human cytomegalovirus infection";"RSK activation";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-stimulated signaling through PRKCZ";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"VEGFR2 mediated cell proliferation";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"Downstream TCR signaling"
XP_035738694.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_035741253.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035728984.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035723735.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035727143.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_035727851.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035732269.1	16	Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1236394;Reactome: R-HSA-5673001;Reactome: R-HSA-1250347;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-1250342;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1251985	"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB4";"RAF/MAP kinase cascade";"SHC1 events in ERBB4 signaling";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Nuclear signaling by ERBB4"
XP_035739404.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_035738197.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035730726.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035720957.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_035727457.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035720405.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035726004.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_035724956.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025	"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions"
XP_035737140.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035726058.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035735134.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035734968.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035741578.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035742182.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035734949.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_035736832.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_035741229.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035729821.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035734507.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035721846.1	9	Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade"
XP_035743446.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_035717247.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035732834.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035732248.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035739565.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035721820.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035742336.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_035743840.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_035728453.1	8	Reactome: R-HSA-4608870;Reactome: R-HSA-8856828;Reactome: R-HSA-4086398;Reactome: R-HSA-4641263;Reactome: R-HSA-373080;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-5340588	"Asymmetric localization of PCP proteins";"Clathrin-mediated endocytosis";"Ca2+ pathway";"Regulation of FZD by ubiquitination";"Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"RNF mutants show enhanced WNT signaling and proliferation"
XP_035721426.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035729847.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability"
XP_035731157.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-936837	"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"RAF activation";"HSF1-dependent transactivation";"Ion homeostasis";"Long-term potentiation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases"
XP_035727190.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035740676.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035742156.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_035731705.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035738882.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035729441.1	4	Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_035735240.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035737234.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_035728702.1	3	Reactome: R-HSA-2151201;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Transcriptional activation of mitochondrial biogenesis";"UCH proteinases";"HATs acetylate histones"
XP_035742565.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_035728147.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_035739199.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035723864.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035718194.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035741464.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035743973.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_035727978.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_035718101.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035731213.1	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol"
XP_035734731.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035723419.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_035722894.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035740038.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_035729396.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035735375.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035731088.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_035723512.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035741725.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035725413.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035720222.1	7	KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_035721210.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035732649.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated"
XP_035717626.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035740954.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035723745.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035731209.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035727133.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035731976.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_035741803.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035744270.1	11	Reactome: R-HSA-72163;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-8941856	"mRNA Splicing - Major Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling"
XP_035737350.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_035736713.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035718722.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_035730730.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035727294.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035727353.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035737130.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_035729359.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_035718663.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035741780.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300	"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_035727086.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035726710.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_035735167.1	1	Reactome: R-HSA-419771	"Opsins"
XP_035741032.1	5	MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate"
XP_035719331.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035718143.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325	"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis"
XP_035718851.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_035735428.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035733565.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035721472.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_035722151.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035726680.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_035718898.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035728260.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_035740622.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035741421.1	6	MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_035723821.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_035738310.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_035717849.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035720671.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035724014.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035722331.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-176187	"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress"
XP_035720325.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035732840.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035735272.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035738263.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035733336.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035734673.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035720068.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035726625.1	13	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse"
XP_035741841.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_035743248.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_035717429.1	5	Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16	"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035729249.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_035732169.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035726967.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-205043	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"NRIF signals cell death from the nucleus"
XP_035738297.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035718035.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035728630.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_035723847.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035717522.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035732611.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_035720380.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035735234.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035723616.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035735848.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_035730910.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_035725052.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035736019.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035730865.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_035729512.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035732304.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035718776.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035725978.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_035744242.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_035722535.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_035743418.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035723211.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_035721818.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035729786.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_035721629.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035739806.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035734911.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035743649.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035736178.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035730744.1	7	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_035734523.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_035731807.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035717264.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035729648.1	11	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-8866654	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"IRF3-mediated induction of type I IFN";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035740534.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035728980.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Estrogen-dependent gene expression";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
XP_035721787.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035724162.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035735350.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_035739400.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035725201.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035737816.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035719970.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_035724546.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035732973.1	42	Reactome: R-HSA-5693607;Reactome: R-HSA-606279;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-2559586;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-1912408;Reactome: R-HSA-5693565;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-212300;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-3214847	"Processing of DNA double-strand break ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"DNA Damage/Telomere Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"Estrogen-dependent gene expression";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Opening";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"Pre-NOTCH Transcription and Translation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"PRC2 methylates histones and DNA";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"HATs acetylate histones"
XP_035742806.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_035735130.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035737144.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_035717672.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035731584.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035724883.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_035740171.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035741042.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_035719341.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035734445.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035735095.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035737660.1	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_035734452.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035718086.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3232118;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)"
XP_035722341.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035734880.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_035732830.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035743424.1	12	Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482	"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"DCC mediated attractive signaling";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"G alpha (12/13) signalling events"
XP_035727663.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_035725329.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035743668.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035728811.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035717839.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035724561.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_035744170.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035734486.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035727101.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035739795.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation"
XP_035738408.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035735244.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035728640.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613	"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation"
XP_035739651.1	9	Reactome: R-HSA-8963684;KEGG: 00950+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5	"Tyrosine catabolism";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism"
XP_035720701.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_035726873.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035741460.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035721306.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_035736943.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035739256.1	10	KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_035719890.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035726940.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_035721214.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_035742299.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035722712.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_035725851.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_035740950.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035718606.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035739282.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035731257.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035729638.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035727290.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035730734.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035736517.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_035737637.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035733404.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035724536.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035723466.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377	"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_035732461.1	6	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling"
XP_035717121.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_035733458.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_035737293.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035741784.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035729307.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_035725905.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_035719254.1	3	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_035735219.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035733088.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035742807.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_035727762.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035726252.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035719208.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_035724547.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035724909.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168	"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035737817.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035730911.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035733213.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035734744.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035730523.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_035721419.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035725369.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035727623.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling"
XP_035731806.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035722208.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors"
XP_035741973.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035720585.1	9	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-416476	"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events"
XP_035739807.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035721648.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_035724913.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035724039.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_035741358.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035732217.1	17	Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-5689880;Reactome: R-HSA-4086398;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956	"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"Ub-specific processing proteases";"Ca2+ pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway"
XP_035735131.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035730188.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035720495.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035738742.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035734910.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035723062.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_035738604.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_035718777.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035717356.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_035728981.1	16	Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548	"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks"
XP_035727854.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035739401.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035719089.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035727808.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035723617.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes"
XP_035738084.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738311.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_035731324.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944	"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2"
XP_035720670.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035737227.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_035741169.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035737570.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035735618.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035724380.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035729472.1	4	KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate"
XP_035732841.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035738296.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035726966.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035732447.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_035735715.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035730673.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-7254	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)"
XP_035736904.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035717448.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035729228.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782	"Anandamide biosynthesis I";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Ether lipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Plasmalogen biosynthesis"
XP_035740519.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_035726681.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_035722150.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035732333.1	4	Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9	"Peroxisomal protein import";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism"
XP_035718592.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035741485.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_035723885.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035718456.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_035720381.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035732827.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035741595.1	3	KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_035733443.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_035717161.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035735555.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_035740503.1	5	KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;MetaCyc: PWY-6580;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism"
XP_035738259.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035734099.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035735449.1	8	Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244	"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation"
XP_035736782.1	5	Reactome: R-HSA-964975;MetaCyc: PWY-7204;Reactome: R-HSA-6798695;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_035735127.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035730215.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472	"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035719891.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035726941.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035731318.1	4	Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-3232142;Reactome: R-HSA-8951664	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of ubiquitinylation proteins";"Neddylation"
XP_035723128.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_035718338.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035724537.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035727875.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035741867.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035737636.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035740662.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_035736516.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_035722858.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_035741461.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035740723.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_035718191.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035731256.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035733896.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_035738774.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035719497.1	37	Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-983170;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-2132295;Reactome: R-HSA-9639288;Reactome: R-HSA-9648025;Reactome: R-HSA-204005;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531	"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"snRNP Assembly";"MHC class II antigen presentation";"Amino acids regulate mTORC1";"EML4 and NUDC in mitotic spindle formation";"COPII-mediated vesicle transport";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus"
XP_035718607.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035734734.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035738223.1	17	Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-6722;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789	"Biotin transport and metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Propanoate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Carnitine metabolism";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_035722891.1	8	MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_035742364.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035725589.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035732460.1	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035743301.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035735853.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035733490.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035721638.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_035728285.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035724049.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_035732129.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_035739257.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_035726768.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_035721735.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035727258.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035740951.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035725850.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_035743253.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_035740232.1	5	KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism"
XP_035719275.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_035725592.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035721307.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_035717562.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035731299.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_035738732.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035723493.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_035727291.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035722340.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2871809;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-114604	"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"FCERI mediated Ca+2 mobilization";"Rho GTPase cycle";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade"
XP_035742109.1	9	MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450"
XP_035734881.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035732831.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035737119.1	6	Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368	"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_035728810.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035728627.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035719326.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_035740170.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035743614.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_035719340.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035738813.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035734487.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035737661.1	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_035729824.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035730452.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-5690	"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)"
XP_035728792.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell"
XP_035721239.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035717773.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035737231.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_035731795.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_035732042.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035737078.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035742113.1	9	MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18	"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione metabolism"
XP_035720700.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_035743505.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_035720883.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_035738809.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035721988.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035735439.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035727100.1	7	Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035736871.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756	"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation"
XP_035722779.1	17	Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942	"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)"
XP_035724743.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions"
XP_035719250.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_035724957.1	5	Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873	"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation"
XP_035724405.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)"
XP_035725875.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_035720956.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_035717631.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-8849471	"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_035729861.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035731863.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035737624.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035730727.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035738196.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035742490.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-9018519	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression"
XP_035734740.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035738912.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035721860.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_035722250.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378	"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling"
XP_035723306.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035729493.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035720999.1	9	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035728603.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_035727499.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_035730689.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731	"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_035721466.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_035731458.1	16	Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035737141.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035733257.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_035717261.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035742525.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_035727850.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035731897.1	15	Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_035738159.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035727482.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_035735266.1	5	Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383	"Gluconeogenesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_035723824.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035719154.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325	"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis"
XP_035718995.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_035741424.1	6	KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-7761	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_035741668.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035723110.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035728218.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695	"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Neutrophil degranulation"
XP_035720674.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035730312.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035726903.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035732070.1	10	KEGG: 00130+2.1.1.163;MetaCyc: PWY-5844;MetaCyc: PWY-5849;MetaCyc: PWY-7996;MetaCyc: PWY-5895;Reactome: R-HSA-2142789;MetaCyc: PWY-5892;MetaCyc: PWY-5839;MetaCyc: PWY-5890;MetaCyc: PWY-5891	"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis"
XP_035719108.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_035731320.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035739778.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_035719073.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035724011.1	4	KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate"
XP_035731346.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035736900.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035718808.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035719334.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035743042.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_035739321.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_035730009.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035735661.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035718854.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035742433.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_035725696.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_035723653.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_035738025.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035735078.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035735952.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_035740566.1	25	Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-381771;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-9009391	"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (s) signalling events";"G alpha (q) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling"
XP_035732117.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_035735231.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035729430.1	30	Reactome: R-HSA-69202;Reactome: R-HSA-8876198;Reactome: R-HSA-198693;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-9634638;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-8948751;Reactome: R-HSA-5674400;Reactome: R-HSA-6804758;Reactome: R-HSA-8941332;Reactome: R-HSA-389513;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-6804759;Reactome: R-HSA-211163;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-199418;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-111447;Reactome: R-HSA-69656;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1358803	"Cyclin E associated events during G1/S transition";"RAB GEFs exchange GTP for GDP on RABs";"AKT phosphorylates targets in the nucleus";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN stability and activity";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Activity through Acetylation";"RUNX2 regulates genes involved in cell migration";"CTLA4 inhibitory signaling";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Association with Co-factors";"AKT-mediated inactivation of FOXO1A";"Human cytomegalovirus infection";"mTOR signaling pathway";"Negative regulation of the PI3K/AKT network";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of localization of FOXO transcription factors";"Activation of BAD and translocation to mitochondria";"Cyclin A:Cdk2-associated events at S phase entry";"Relaxin signaling pathway";"Downregulation of ERBB2:ERBB3 signaling"
XP_035725659.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport"
XP_035719372.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_035726186.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035739347.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035738207.1	6	MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-191273	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis"
XP_035735945.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_035718623.1	7	Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_035728399.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_035736612.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035741844.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_035739433.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_035721431.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035727087.1	1	Reactome: R-HSA-419771	"Opsins"
XP_035726598.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035735620.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_035724733.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035722783.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_035719800.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_035721211.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035727369.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035718659.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035717789.1	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_035718100.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035734730.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035717627.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035721139.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035735685.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035737131.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_035733584.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_035717124.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035741781.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_035732819.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035743390.1	7	MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702	"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phytate degradation I"
XP_035725854.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_035737351.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_035744271.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035741649.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_035735788.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism"
XP_035730731.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035732725.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035735227.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_035722344.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-194840;Reactome: R-HSA-2871796	"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"Rho GTPase cycle";"FCERI mediated MAPK activation"
XP_035728146.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787	"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state"
XP_035728469.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination"
XP_035731336.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035721821.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035742608.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035737829.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035728814.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035740677.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_035723472.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_035731156.1	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_035729846.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
XP_035721427.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035735005.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035742705.1	12	Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381033;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-114608;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-6798695	"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Platelet degranulation";"IRE1alpha activates chaperones";"PERK regulates gene expression";"Neutrophil degranulation"
XP_035719344.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_035718258.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035726342.1	10	Reactome: R-HSA-5357905;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2	"Regulation of TNFR1 signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"T cell receptor signaling pathway"
XP_035718875.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358751	"APC truncation mutants have impaired AXIN binding";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated"
XP_035732578.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035727338.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_035738588.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_035717577.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_035735241.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035738498.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035720758.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_035732229.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035717246.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035720704.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_035721847.1	9	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Synaptic adhesion-like molecules"
XP_035741248.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035743902.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_035739443.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035727158.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_035720655.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
XP_035743841.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_035727104.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_035738857.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148	"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035740345.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_035731199.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035729885.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_035739337.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035736862.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035737137.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035732512.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035737634.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_035735640.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035733407.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035720534.1	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism"
XP_035744162.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_035730305.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035733894.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_035725643.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035721390.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035734736.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035736514.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035743139.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035733942.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035740276.1	52	Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-167172	"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome"
XP_035735811.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035731089.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_035717647.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035732648.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358751	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated"
XP_035717144.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555	"Downstream signal transduction";"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1"
XP_035718983.1	7	MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-70221;Reactome: R-HSA-6798695	"Glycogen degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation"
XP_035721217.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_035718690.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_035719400.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035740039.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_035723418.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_035740913.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_035731092.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_035732403.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035727979.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_035728126.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035735247.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_035717571.1	57	Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5610785	"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of DVL";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome"
XP_035724519.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_035739198.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_035728140.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_035718310.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035721841.1	13	Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism"
XP_035737849.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase"
XP_035731330.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035724412.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035727601.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035730501.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_035738143.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035743616.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
XP_035726023.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035717240.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035743168.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_035723872.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035738035.1	18	MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_035741472.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035743427.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035721610.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035720763.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_035736020.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035739423.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035721421.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035740671.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035740325.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_035728869.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_035729611.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_035742331.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035734948.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_035727450.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035727882.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035734969.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035731587.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035737147.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_035737644.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035737702.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_035717172.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035743149.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035717267.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035733932.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_035721866.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_035742586.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035735309.1	24	Reactome: R-HSA-202424;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-2871837;KEGG: 04926+2.7.11.1	"Downstream TCR signaling";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"mTOR signaling pathway";"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Integrin signaling";"RHO GTPases activate PKNs";"Activation of AKT2";"FCERI mediated NF-kB activation";"Relaxin signaling pathway"
XP_035734720.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035731891.1	9	Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801	"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD"
XP_035721784.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035733298.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035734746.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035717293.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_035736061.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_035724232.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_035722282.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_035742552.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels"
XP_035725310.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035727856.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035739586.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239	"Cilium Assembly";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1"
XP_035734785.1	14	KEGG: 00630+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201	"Glyoxylate and dicarboxylate metabolism";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Methane metabolism";"One carbon pool by folate";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Folate transformations I"
XP_035732735.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_035744028.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_035735313.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1	"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"GPVI-mediated activation cascade";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"Integrin signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Relaxin signaling pathway"
XP_035738606.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_035742545.1	10	Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-427413	"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression"
XP_035722299.1	5	MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)"
XP_035725475.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035739496.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035719282.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_035732307.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035724805.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035723238.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035722962.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035731340.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035724170.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_035737839.1	17	MetaCyc: PWY-7179;MetaCyc: PWY-6620;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5532	"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine salvage";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)"
XP_035738086.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035735237.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035723071.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_035731326.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_035732076.1	9	MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Pyruvate metabolism";"Gluconeogenesis"
XP_035739341.1	10	MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-5484	"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_035738201.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035721343.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035723989.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_035725690.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_035740794.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035735980.1	8	MetaCyc: PWY-7400;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-4984;Reactome: R-HSA-70635	"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Urea cycle"
XP_035742327.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_035726964.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035738294.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035741653.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_035736279.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_035726125.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035734054.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_035736906.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035719962.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_035738045.1	18	MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_035729436.1	10	Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837	"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation"
XP_035732239.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035727328.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035717230.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035736183.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035724017.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035722795.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-5578749	"Nuclear import of Rev protein";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs"
XP_035735667.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035717987.1	7	MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840	"Ophthalmate biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis"
XP_035738978.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035719795.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035735164.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035721055.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-113418;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-77588;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-159227;Reactome: R-HSA-72163;Reactome: R-HSA-975956;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72086;Reactome: R-HSA-975957;Reactome: R-HSA-8851708	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"Formation of the Early Elongation Complex";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Capping";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Signaling by FGFR2 IIIa TM"
XP_035734938.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_035726180.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_035722651.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035738052.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_035741110.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035727771.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_035737630.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035735644.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_035743735.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_035722863.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035739251.1	10	MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842	"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II"
XP_035727633.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692	"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity"
XP_035733890.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_035721394.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035742319.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035727297.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_035717414.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035736510.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035735453.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_035739303.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_035732860.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_035742298.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035727310.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_035720048.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484	"Chylomicron remodeling";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"LDL clearance";"Post-translational protein phosphorylation";"Chylomicron clearance";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Retinoid metabolism and transport";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Scavenging by Class F Receptors"
XP_035717140.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035727263.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035733586.1	30	Reactome: R-HSA-5676590;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-2122947;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-2644607;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5684264	"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Circadian Clock";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Iron uptake and transport";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_035717126.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_035724029.1	34	Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-69202;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-8939236;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-69656;Reactome: R-HSA-77075;Reactome: R-HSA-69273;Reactome: R-HSA-6782210	"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Cyclin E associated events during G1/S transition";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin A/B1/B2 associated events during G2/M transition";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_035719581.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035741128.1	7	Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-2173796	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G0 and Early G1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_035741467.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035718197.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035718601.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035725856.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_035722897.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035742303.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035741430.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035738409.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_035718314.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035718081.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035727983.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035720483.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035743988.1	15	Reactome: R-HSA-9665249;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-9665251;Reactome: R-HSA-9665247;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-1227986;Reactome: R-HSA-5637810;Reactome: R-HSA-8863795;Reactome: R-HSA-1236382;Reactome: R-HSA-9652282;Reactome: R-HSA-9665233;Reactome: R-HSA-9665246	"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2";"Constitutive Signaling by EGFRvIII";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to neratinib"
XP_035728144.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378	"G alpha (s) signalling events";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling"
XP_035728647.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505	"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_035744262.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035719346.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_035739682.1	6	Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035729992.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035731073.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035730852.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_035731154.1	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_035740176.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035732837.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035743669.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035725328.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035729424.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_035717244.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035717838.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035733327.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035743076.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035736024.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035744010.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_035719385.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035727106.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_035729765.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_035730425.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723138.1	18	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_035727454.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035743745.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_035739942.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035737626.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035739801.1	15	Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-141430	"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_035721803.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035741062.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_035735634.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_035737640.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035718771.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035731800.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_035723304.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035736179.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035739407.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_035739955.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035740733.1	17	Reactome: R-HSA-113418;Reactome: R-HSA-674695;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167243;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167242	"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"T cell receptor signaling pathway";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_035722977.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035728987.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035723391.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035721628.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035724541.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035731406.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_035726937.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_035742801.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745	"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_035729418.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258	"Downstream TCR signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Degradation of DVL"
XP_035721819.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035736283.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_035717130.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_035735672.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035738722.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_035730917.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases"
XP_035742407.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035718065.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_035741210.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_035736018.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035740222.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_035719565.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_035728637.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_035731344.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035723826.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035719156.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-165054	"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA"
XP_035720676.1	6	Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-6174	"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)"
XP_035728293.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035728354.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035717167.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_035743249.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_035725197.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis"
XP_035729248.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_035725694.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_035717428.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation"
XP_035732168.1	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism"
XP_035719336.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_035734050.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_035738290.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035726960.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_035733198.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035720069.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_035725601.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035728172.1	13	KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism"
XP_035740564.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_035724132.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_035723611.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_035718882.1	6	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035733423.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_035717848.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035718899.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035741846.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399	"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Aggrephagy"
XP_035740812.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035726184.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_035735429.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035728267.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_035744124.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035730294.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035725602.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035743876.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035720350.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035733903.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035733145.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035737733.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035719918.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035723548.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_035725910.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_035740811.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035718597.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035733919.1	3	Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072	"Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels"
XP_035725865.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035741528.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_035741906.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035735521.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_035718881.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358751	"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated"
XP_035723030.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035732455.1	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035717540.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035717908.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035735039.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035733186.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_035728171.1	13	MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism"
XP_035717526.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035724203.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035723612.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes"
XP_035724131.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_035731926.1	29	Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167200	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_035742768.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_035730190.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035735068.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035738953.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585	"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of DVL";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G"
XP_035740576.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_035738747.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035736214.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_035732212.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035719362.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167200	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_035736306.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_035719097.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-418597	"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events"
XP_035724618.1	12	MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1	"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Propanoate metabolism"
XP_035739941.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035737790.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035742665.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035720848.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035739802.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035728950.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035744285.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_035727928.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035740221.1	5	MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_035720428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035732060.1	9	Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1	"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_035719063.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_035718734.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035733090.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035734607.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035737564.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_035734104.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_035724166.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_035725099.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035724449.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035735671.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035724542.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035739665.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483	"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Carnitine metabolism";"Lipophagy";"Activation of AMPK downstream of NMDARs"
XP_035723093.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_035742802.1	13	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8856828	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis"
XP_035721517.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-5651801	"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair"
XP_035742370.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_035730143.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_035739681.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism"
XP_035721683.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_035729072.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_035725734.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_035729991.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035740309.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_035734456.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035724624.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035733135.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035739749.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_035731728.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_035734850.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768	"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of DVL";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Degradation of AXIN";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_035726015.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035727914.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035732539.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_035723026.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035731371.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035730035.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035740260.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035732021.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035731625.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
YP_009915665.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035735049.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035731967.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035718865.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_035732568.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_035738737.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035742286.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035738305.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_035733598.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_035741605.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_035737384.1	10	KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Cyanoamino acid metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_035724574.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_035739252.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826	"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis"
XP_035719924.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035717706.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_035735794.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_035718602.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035722716.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_035718744.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_035722489.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_035719582.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035741514.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes"
XP_035720095.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035740667.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_035722582.1	5	MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-71336;Reactome: R-HSA-6798695	"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation"
XP_035740164.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035739094.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_035742931.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway"
XP_035719716.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035721003.1	9	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation"
XP_035728069.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_035721205.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035725740.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_035718506.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_035744120.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035719961.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035720308.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035738202.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035741997.1	7	KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Ether lipid metabolism";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA"
XP_035744146.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035720293.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035723991.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_035735743.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035735405.1	24	Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-420092	"G alpha (q) signalling events";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors"
XP_035735957.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_035737537.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695	"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation"
XP_035734875.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035722961.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035723958.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035720134.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035722652.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035742135.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_035727772.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035742342.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035738098.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_035733415.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035743047.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_035723034.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035721041.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035734316.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035721874.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_035736426.1	4	MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_035719652.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_035726608.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway"
XP_035722645.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035726654.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035731892.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035720987.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_035730194.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035733931.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_035730233.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_035741018.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_035734696.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_035736210.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035721709.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_035719936.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_035717171.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035731889.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_035726213.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_035720230.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_035727881.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035739488.1	44	Reactome: R-HSA-9649948;Reactome: R-HSA-375165;Reactome: R-HSA-5668599;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-74749;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-450341;Reactome: R-HSA-456926;Reactome: R-HSA-162658;Reactome: R-HSA-6802948;Reactome: R-HSA-5654727;Reactome: R-HSA-2559585;Reactome: R-HSA-6802946;Reactome: R-HSA-879415;Reactome: R-HSA-2559580;Reactome: R-HSA-5674499;Reactome: R-HSA-2871796;Reactome: R-HSA-444257;Reactome: R-HSA-5663213;Reactome: R-HSA-5674135;Reactome: R-HSA-8940973;Reactome: R-HSA-202670;Reactome: R-HSA-6802952;Reactome: R-HSA-1295596;Reactome: R-HSA-2029482;Reactome: R-HSA-198753;Reactome: R-HSA-112409;Reactome: R-HSA-445144;Reactome: R-HSA-881907;Reactome: R-HSA-5654726;Reactome: R-HSA-5675221;Reactome: R-HSA-5654733;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.24;Reactome: R-HSA-982772;Reactome: R-HSA-2559582;Reactome: R-HSA-6811558;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-5654732;Reactome: R-HSA-9627069;Reactome: R-HSA-8943724	"Signaling downstream of RAS mutants";"NCAM signaling for neurite out-growth";"RHO GTPases Activate NADPH Oxidases";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signal attenuation";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Activation of the AP-1 family of transcription factors";"Thrombin signalling through proteinase activated receptors (PARs)";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR2 signaling";"Oncogene Induced Senescence";"Signaling by moderate kinase activity BRAF mutants";"Advanced glycosylation endproduct receptor signaling";"Oxidative Stress Induced Senescence";"Negative feedback regulation of MAPK pathway";"FCERI mediated MAPK activation";"RSK activation";"RHO GTPases Activate WASPs and WAVEs";"MAP2K and MAPK activation";"RUNX2 regulates osteoblast differentiation";"ERKs are inactivated";"Signaling by BRAF and RAF fusions";"Spry regulation of FGF signaling";"Regulation of actin dynamics for phagocytic cup formation";"ERK/MAPK targets";"RAF-independent MAPK1/3 activation";"Signal transduction by L1";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative regulation of FGFR1 signaling";"Negative regulation of MAPK pathway";"Negative regulation of FGFR4 signaling";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Growth hormone receptor signaling";"Senescence-Associated Secretory Phenotype (SASP)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ESR-mediated signaling";"Frs2-mediated activation";"Negative regulation of FGFR3 signaling";"Regulation of the apoptosome activity";"Regulation of PTEN gene transcription"
XP_035737794.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035733001.1	4	Reactome: R-HSA-72203;Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-9610379	"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"HCMV Late Events"
XP_035720660.1	6	Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-922	"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I"
XP_035724945.1	12	KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II"
XP_035718730.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_035734100.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035742598.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-163765	"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression"
XP_035733286.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174430	"Termination of translesion DNA synthesis";"DNA replication initiation";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation"
XP_035736062.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035721713.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_035742551.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300	"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors"
XP_035722281.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_035742488.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_035741024.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_035734623.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035723295.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035730502.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_035739332.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_035726321.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin"
XP_035743907.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_035727602.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035738590.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_035721842.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_035726778.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035724620.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035719265.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_035720144.1	13	Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-937042;Reactome: R-HSA-2871837	"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation"
XP_035737909.1	7	KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2	"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism"
XP_035724817.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_035730409.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_035738845.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035742033.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359	"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation"
XP_035734762.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-2151201	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis"
XP_035738425.1	18	Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)"
XP_035742332.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_035735478.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_035743037.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_035721422.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035727865.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035742145.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035721278.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035741471.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035740264.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035720621.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035722635.1	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_035720375.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035739033.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035737913.1	7	KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539	"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism"
XP_035730413.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035737039.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035733941.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035730243.1	29	Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-2559586;Reactome: R-HSA-6803204;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-6803207;Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-349425;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-69541	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Stabilization of p53"
XP_035719769.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035743388.1	7	KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis"
XP_035727056.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035723782.1	12	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-416482	"Relaxin signaling pathway";"Signaling by FGFR1 in disease";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"G alpha (12/13) signalling events"
XP_035723799.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035719920.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_035744161.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035736861.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035729392.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035732511.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_035731091.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_035727099.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_035741510.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035718726.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_035740522.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_035728975.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035732695.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_035725928.1	42	Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-5625886;Reactome: R-HSA-212300;Reactome: R-HSA-3214815;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-1912408;Reactome: R-HSA-9610379;Reactome: R-HSA-3214842;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-3214858;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580	"DNA methylation";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA";"HDACs deacetylate histones";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Pre-NOTCH Transcription and Translation";"HCMV Late Events";"HDMs demethylate histones";"Meiotic synapsis";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"RMTs methylate histone arginines";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence"
XP_035719985.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035740160.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035735812.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035740429.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_035718938.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation"
XP_035736830.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_035740219.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1"
XP_035726341.1	10	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TNFR1 signaling";"T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035731918.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035725736.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_035741871.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035727273.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035739125.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035721822.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035743422.1	12	KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482	"Relaxin signaling pathway";"G alpha (q) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"DCC mediated attractive signaling";"G alpha (12/13) signalling events"
XP_035741477.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035734454.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035720416.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035738445.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859	"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly"
XP_035727916.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_035735255.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035738703.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035718008.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484	"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)"
XP_035743901.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_035742125.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035723024.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035738880.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035737541.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_035720792.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035727189.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035735242.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035730223.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha"
XP_035743679.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_035733921.1	5	MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_035736148.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035744193.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_035717655.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275	"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"LDL remodeling";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL assembly";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance";"Post-translational protein phosphorylation"
XP_035732105.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_035726459.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035740618.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035739059.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035724247.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_035717791.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_035725761.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_035721212.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035724576.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_035737386.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis"
XP_035717758.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_035738215.1	17	MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679	"Candicidin biosynthesis";"Carnitine metabolism";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis"
XP_035717704.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_035737174.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035729775.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_035735796.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_035721060.1	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_035741516.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580	"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence"
XP_035718720.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_035736461.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state"
XP_035730732.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035733947.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035744272.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035737352.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_035737345.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_035744167.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035741782.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_035720285.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035731063.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035733402.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035740166.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035736867.1	19	Reactome: R-HSA-983231;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-5627123;Reactome: R-HSA-182971;Reactome: R-HSA-525793;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-8950505;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-114604	"Factors involved in megakaryocyte development and platelet production";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"RHO GTPases activate PAKs";"EGFR downregulation";"Myogenesis";"Rho GTPase cycle";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade"
XP_035717518.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035739096.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_035721388.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035735503.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_035734297.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_035724309.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035721474.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035744140.1	4	MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22	"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism"
XP_035729085.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035725720.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035734633.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_035741034.1	5	MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate"
XP_035732683.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035735662.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035725746.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis"
XP_035718500.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035744126.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_035730296.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_035735723.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035726198.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_035742023.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation"
XP_035724012.1	4	Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_035741373.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_035717999.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035718075.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035730311.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035722680.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554	"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_035730259.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035727395.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035719967.1	9	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-110314	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex"
XP_035740853.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_035726423.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035724313.1	10	Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916	"HS-GAG degradation";"Other glycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation"
XP_035736611.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035735951.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_035733184.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_035717524.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035722371.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035735232.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035725688.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_035720631.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412	"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C"
XP_035734310.1	17	MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism"
XP_035722625.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035735998.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445	"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation"
XP_035719287.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035740574.1	5	Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_035736216.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_035721568.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_035731165.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"HSF1-dependent transactivation";"Long-term potentiation";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"RAF activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions"
XP_035736138.1	4	Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2	"Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_035738911.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035724693.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035732019.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035729862.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035736358.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035718736.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035737566.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-182218	"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation"
XP_035734106.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_035731716.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035725938.1	7	Reactome: R-HSA-212436;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression"
XP_035724925.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035724164.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_035727481.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_035743553.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035730107.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035722000.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035717262.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035720666.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_035731582.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035732178.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035740439.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_035737142.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_035719000.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035722575.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035727887.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035737335.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035739557.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_035735017.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315	"Methylation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol"
XP_035728585.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035744095.1	8	MetaCyc: PWY-6580;MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-6372;MetaCyc: PWY-2301	"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis"
XP_035741040.1	5	MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate"
XP_035737662.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_035742687.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035742184.1	4	MetaCyc: PWY-6906;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210	"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_035731377.1	19	KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;Reactome: R-HSA-75105;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II"
XP_035721996.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_035728518.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_035734450.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035737723.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_035738115.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035734882.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_035720469.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_035737274.1	6	MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism"
XP_035727969.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_035732832.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035736872.1	5	Reactome: R-HSA-6804756;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-1169408	"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"ISG15 antiviral mechanism"
XP_035730857.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035734856.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035738949.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;MetaCyc: PWY-5872	"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_035725395.1	7	KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7219;MetaCyc: PWY-7234	"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_035724868.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_035744172.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035728655.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613	"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation"
XP_035718050.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_035727785.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
XP_035741538.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035738766.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159236	"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035744267.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035728704.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-2151201	"HATs acetylate histones";"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis"
XP_035728758.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_035737998.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035730498.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035735531.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035738884.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035737232.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_035740266.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035721959.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035742729.1	7	MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;Reactome: R-HSA-71336	"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_035740119.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035722892.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035727008.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway"
XP_035725718.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035718192.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035727173.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035734065.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_035742280.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_035725615.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035720773.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035719550.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_035728879.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_035719892.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035722889.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035724839.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035718724.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_035717561.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035725591.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035727292.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035734771.1	8	Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Regulation of PTEN localization";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_035740103.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_035740952.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035739280.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035743933.1	5	MetaCyc: PWY-7210;Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I"
XP_035725887.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035739937.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035735335.1	10	Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111457	"Respiratory electron transport";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria"
XP_035737017.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035729283.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes"
XP_035730349.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_035736418.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_035727289.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035726682.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_035740620.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035724357.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
XP_035731265.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_035718558.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035736844.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-450520;Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"HuR (ELAVL1) binds and stabilizes mRNA";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035738009.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035729877.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035718504.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035723906.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035721315.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035732842.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035729471.1	4	KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_035737878.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035718887.1	4	KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621	"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism"
XP_035735270.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035724137.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_035720218.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035728674.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035738312.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_035717495.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035738939.1	12	MetaCyc: PWY-5857;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;MetaCyc: PWY-5870	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_035741548.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035734979.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035731738.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_035725916.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_035725192.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035717162.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035717520.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_035721876.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_035731635.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_035717277.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035738288.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035743476.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035720382.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_035718615.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172	"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome"
XP_035726656.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035723036.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_035730025.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035734197.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_035744240.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035734694.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_035730912.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_035731920.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035730196.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035742509.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035720619.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_035735677.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035737796.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035739513.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69091	"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Polymerase switching"
XP_035731769.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_035727761.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_035719934.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_035726251.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-5696397;Reactome: R-HSA-5649702	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_035728982.1	16	Reactome: R-HSA-5685942;Reactome: R-HSA-9018519;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938	"HDR through Homologous Recombination (HRR)";"Estrogen-dependent gene expression";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)"
XP_035743943.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035720448.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-5789	"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_035740241.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035739402.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035738741.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035723061.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_035731985.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_035730600.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035721798.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035733284.1	11	Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-68952	"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"DNA replication initiation"
XP_035726002.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_035741067.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035739947.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035737759.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_035728999.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035720603.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_035732679.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035732823.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035723609.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_035728291.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035733447.1	13	KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-2261;MetaCyc: PWY-7533	"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis"
XP_035737732.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035735159.1	8	Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2	"Transferrin endocytosis and recycling";"ATP biosynthesis";"Ion channel transport";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Photosynthesis"
XP_035738266.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035730352.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_035723150.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-380972	"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035718146.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_035725603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035730345.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_035741199.1	14	MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)"
XP_035722820.1	39	Reactome: R-HSA-5673001;Reactome: R-HSA-1839122;Reactome: R-HSA-190322;Reactome: R-HSA-190375;Reactome: R-HSA-8853338;Reactome: R-HSA-5654706;Reactome: R-HSA-190372;Reactome: R-HSA-1839130;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-5654689;Reactome: R-HSA-5654727;Reactome: R-HSA-1257604;Reactome: R-HSA-5654710;Reactome: R-HSA-109704;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-5654687;Reactome: R-HSA-2033514;Reactome: R-HSA-2033519;Reactome: R-HSA-5654688;Reactome: R-HSA-5654693;Reactome: R-HSA-5658623;Reactome: R-HSA-2219530;Reactome: R-HSA-190373;Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-190371;Reactome: R-HSA-5654228;Reactome: R-HSA-5654219;Reactome: R-HSA-5654699;Reactome: R-HSA-5654712;Reactome: R-HSA-5654720;Reactome: R-HSA-5654704;Reactome: R-HSA-5655253;Reactome: R-HSA-5654719;Reactome: R-HSA-5654732;Reactome: R-HSA-6811558;Reactome: R-HSA-5654221	"RAF/MAP kinase cascade";"Signaling by activated point mutants of FGFR1";"FGFR4 ligand binding and activation";"FGFR2c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"FRS-mediated FGFR3 signaling";"FGFR3c ligand binding and activation";"Signaling by activated point mutants of FGFR3";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"PI-3K cascade:FGFR1";"Negative regulation of FGFR2 signaling";"PIP3 activates AKT signaling";"PI-3K cascade:FGFR3";"PI3K Cascade";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"Downstream signaling of activated FGFR1";"FGFR3 mutant receptor activation";"Activated point mutants of FGFR2";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR1 signaling";"FGFRL1 modulation of FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"FGFR3b ligand binding and activation";"Phospholipase C-mediated cascade, FGFR4";"Phospholipase C-mediated cascade: FGFR1";"SHC-mediated cascade:FGFR2";"FRS-mediated FGFR4 signaling";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR3";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR4";"Negative regulation of FGFR3 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2"
XP_035727285.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035735339.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035718814.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035740949.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035734069.1	9	MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_035729175.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex"
XP_035732157.1	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation"
XP_035739578.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_035724202.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035734676.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035732337.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035724835.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035736748.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_035730174.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035732705.1	12	MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-7233	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_035738945.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_035742819.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_035729783.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_035719363.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_035720192.1	3	MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_035733390.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_035719210.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035739803.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_035743401.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis"
XP_035723254.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035742464.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_035724917.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035722210.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035736936.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035740731.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035734271.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_035718438.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_035736281.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_035742803.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900	"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_035738986.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035723092.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_035729406.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035724543.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035725218.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_035727810.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035727627.1	16	Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569	"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_035723089.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_035727965.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-159236	"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035741977.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035734954.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_035733217.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_035734908.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035741361.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035733343.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035728808.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_035731989.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035729334.1	7	KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11	"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methane metabolism"
XP_035720504.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_035728854.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035724425.1	3	Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis"
XP_035718083.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035742117.1	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_035727981.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035737658.1	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_035738788.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_035730155.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_035737107.1	11	MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-5675;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963	"L-glutamine biosynthesis III";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I"
XP_035727666.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_035741385.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035738685.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_035735349.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_035728995.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035736265.1	10	MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;KEGG: 00280+2.3.3.10	"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Butanoate metabolism";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Valine, leucine and isoleucine degradation"
XP_035724886.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035730142.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_035722836.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_035732675.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035729073.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168	"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)"
XP_035730335.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_035718136.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035720887.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_035732321.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035739117.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035724480.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_035736635.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035740312.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1"
XP_035721656.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035741320.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_035734483.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035738817.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035727236.1	5	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_035737515.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_035720615.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035742505.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035733042.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035732347.1	17	Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition"
XP_035724845.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_035726511.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035723804.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580	"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence"
XP_035720395.1	11	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-72163;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-8941856;Reactome: R-HSA-210744	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"mRNA Splicing - Major Pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_035737259.1	14	Reactome: R-HSA-70895;KEGG: 00290+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5104;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5057;MetaCyc: PWY-5108;MetaCyc: PWY-5078;MetaCyc: PWY-7767;MetaCyc: PWY-5101;MetaCyc: PWY-5103	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine biosynthesis";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis IV";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"Cysteine and methionine metabolism";"L-leucine degradation III";"L-valine degradation II";"L-isoleucine biosynthesis V";"L-isoleucine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis III"
XP_035739253.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I"
XP_035722861.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176407	"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_035731300.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_035721298.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_035734975.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035730531.1	57	Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling"
XP_035721303.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_035735451.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035736946.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035718619.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_035734048.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_035727631.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459	"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035738005.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035742253.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035722583.1	5	MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-6798695;Reactome: R-HSA-71336	"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"Pentose phosphate pathway"
XP_035727261.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_035740968.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035721002.1	9	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035737296.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_035732580.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035742301.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035738227.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_035718603.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_035740727.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035733129.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035725814.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035725120.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_035735107.1	5	KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis"
XP_035741795.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035743347.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_035735742.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035725666.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events"
XP_035723073.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_035720292.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035733505.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_035738398.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_035735604.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035719110.1	33	Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142	"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins"
XP_035723108.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_035720938.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035735691.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-174154	"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Regulation of RAS by GAPs";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin"
XP_035740445.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
XP_035722824.1	9	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69205	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"G1/S-Specific Transcription"
XP_035741651.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_035737349.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035718124.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-8854050	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_035734016.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_035731830.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_035740559.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035720289.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035718810.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035738203.1	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_035721341.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035736181.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035737770.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035739042.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035726455.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035743778.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_035725118.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN"
XP_035742437.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_035738219.1	17	MetaCyc: PWY-6722;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679	"Candicidin biosynthesis";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Propanoate metabolism";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis"
XP_035722653.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035739055.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_035735515.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_035740486.1	7	Reactome: R-HSA-499943;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Thiamine metabolism";"Pyrimidine metabolism";"Purine metabolism"
XP_035742343.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035732364.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035729497.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_035719214.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035738166.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035742460.1	10	KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis"
XP_035726212.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_035718246.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035719306.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4086400	"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"PCP/CE pathway"
XP_035720688.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_035731893.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation"
XP_035737451.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_035724378.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_035728338.1	8	Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472	"HCMV Early Events";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_035729804.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035717258.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035739129.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035729275.1	10	MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis";"Galactose metabolism"
XP_035731867.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035738715.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_035724747.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_035740215.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_035724102.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035721712.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035736063.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_035738829.1	11	MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-7560;MetaCyc: PWY-5123;Reactome: R-HSA-191273;MetaCyc: PWY-6859;MetaCyc: PWY-6383;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7102;MetaCyc: PWY-922	"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Methylerythritol phosphate pathway II";"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway I"
XP_035727814.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035742784.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_035727120.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_035735311.1	24	Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"RSK activation";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"RHO GTPases activate PKNs";"Integrin signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_035731461.1	16	Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Tat-mediated HIV elongation arrest and recovery"
XP_035734950.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_035730723.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035734544.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-735;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6	"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism"
XP_035741256.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035730274.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint"
XP_035729330.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_035742610.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_035743705.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_035742827.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035722472.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_035721151.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035739841.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_035731595.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035743443.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_035727448.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_035739074.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035742032.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359	"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation"
XP_035724929.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035722579.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_035731840.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_035730503.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_035739333.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_035744099.1	8	MetaCyc: PWY-6580;MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-2301;MetaCyc: PWY-6372	"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_035734622.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035728589.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_035727603.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035726474.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035728499.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035739447.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation"
XP_035743654.1	4	KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I";"Formation of xylulose-5-phosphate"
XP_035729609.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_035740435.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_035731169.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719	"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Interferon gamma signaling";"Long-term potentiation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors"
XP_035739827.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_035731420.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_035724594.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035737912.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035726021.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_035730412.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_035738624.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_035742333.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035738127.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_035733578.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035728456.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_035733229.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035732015.1	19	Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-432142	"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"LDL clearance";"Post-translational protein phosphorylation";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Platelet sensitization by LDL"
XP_035723175.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035740673.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035725577.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885	"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins"
XP_035721423.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035739421.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035720761.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_035723800.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_035731304.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_035725416.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035730255.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035729393.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035731391.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035743976.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_035729254.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035743209.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex"
XP_035736165.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035731138.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035730242.1	29	Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-349425;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;Reactome: R-HSA-6803204;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-6803207;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-69541;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-5693571	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Human papillomavirus infection";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Relaxin signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Stabilization of p53";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Nonhomologous End-Joining (NHEJ)"
XP_035718118.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_035722818.1	39	Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-5654688;Reactome: R-HSA-5658623;Reactome: R-HSA-5654693;Reactome: R-HSA-2219530;Reactome: R-HSA-190373;Reactome: R-HSA-190371;Reactome: R-HSA-5654228;Reactome: R-HSA-5654219;Reactome: R-HSA-5654699;Reactome: R-HSA-5654712;Reactome: R-HSA-5654704;Reactome: R-HSA-5654720;Reactome: R-HSA-5654732;Reactome: R-HSA-5655253;Reactome: R-HSA-5654719;Reactome: R-HSA-6811558;Reactome: R-HSA-5654221;Reactome: R-HSA-5673001;Reactome: R-HSA-190322;Reactome: R-HSA-1839122;Reactome: R-HSA-5654706;Reactome: R-HSA-190372;Reactome: R-HSA-1839130;Reactome: R-HSA-190375;Reactome: R-HSA-8853338;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-1257604;Reactome: R-HSA-5654689;Reactome: R-HSA-5654727;Reactome: R-HSA-5654695;Reactome: R-HSA-109704;Reactome: R-HSA-5654710;Reactome: R-HSA-2033514;Reactome: R-HSA-2033519;Reactome: R-HSA-5654700;Reactome: R-HSA-5654687	"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"SHC-mediated cascade:FGFR1";"FGFRL1 modulation of FGFR1 signaling";"FRS-mediated FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFR1c ligand binding and activation";"FGFR3b ligand binding and activation";"Phospholipase C-mediated cascade, FGFR4";"Phospholipase C-mediated cascade: FGFR1";"SHC-mediated cascade:FGFR2";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR4";"Negative regulation of FGFR3 signaling";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR2";"RAF/MAP kinase cascade";"FGFR4 ligand binding and activation";"Signaling by activated point mutants of FGFR1";"FRS-mediated FGFR3 signaling";"FGFR3c ligand binding and activation";"Signaling by activated point mutants of FGFR3";"FGFR2c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"PIP3 activates AKT signaling";"PI-3K cascade:FGFR1";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR2";"PI3K Cascade";"PI-3K cascade:FGFR3";"FGFR3 mutant receptor activation";"Activated point mutants of FGFR2";"FRS-mediated FGFR2 signaling";"Downstream signaling of activated FGFR1"
XP_035725641.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035723783.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-5655302;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-1839117;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Signaling by FGFR1 in disease";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Signaling by cytosolic FGFR1 fusion mutants";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_035721535.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035731216.1	9	KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035722787.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_035724737.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035718666.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_035727356.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035739217.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035718981.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035732807.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035717854.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC"
XP_035743088.1	12	MetaCyc: PWY-601;MetaCyc: PWY-801;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6309;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-6936	"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)"
XP_035718079.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035733464.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035732584.1	9	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_035738574.1	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
XP_035727136.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035729971.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_035727218.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_035719787.1	8	Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Activation of RAC1";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035725124.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_035717995.1	7	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2	"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism"
XP_035736716.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035737080.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035742847.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_035718308.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035724507.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035727664.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_035743423.1	12	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Rho GTPase cycle";"G alpha (q) signalling events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"NRAGE signals death through JNK"
XP_035734655.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035720506.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_035726027.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_035734758.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035731617.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035730812.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035724766.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035725571.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035739427.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_035720767.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_035724884.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_035727272.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035722248.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events"
XP_035739168.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis"
XP_035742441.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035731426.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035721654.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035735243.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035738147.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035742427.1	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_035724115.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035728882.1	4	KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
XP_035727234.1	5	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_035739441.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_035722872.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035721213.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_035736889.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_035722781.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5651801	"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair"
XP_035733419.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035724731.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035721360.1	1	Reactome: R-HSA-419771	"Opsins"
XP_035737978.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_035744189.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035719649.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035732407.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035736944.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035739396.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035729977.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_035744192.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035731210.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241	"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_035722649.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035730222.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035743970.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035725621.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_035722418.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035731062.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035737294.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035741783.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events"
XP_035720730.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_035731397.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_035718660.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_035721209.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035739139.1	11	KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine metabolism"
XP_035733403.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035727350.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-6796648	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes"
XP_035725816.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035730733.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_035725647.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events"
XP_035737353.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_035739359.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation"
XP_035735409.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035734879.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_035727130.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035729346.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_035719116.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_035738264.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035728979.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035724013.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_035719992.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_035735722.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035732699.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_035736187.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_035742022.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-164378	"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation in glucagon signalling"
XP_035733669.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035742837.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_035717690.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_035719238.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035718816.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035742431.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282	"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_035740425.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_035718144.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_035738672.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_035735663.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035721321.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_035732682.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035722992.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_035734632.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_035719989.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_035733988.1	10	KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;MetaCyc: PWY-5691;Reactome: R-HSA-975634;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;Reactome: R-HSA-977225	"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Amyloid fiber formation"
XP_035735233.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035735101.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-6811558	"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_035734262.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion"
XP_035738357.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035724009.1	4	KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate"
XP_035730011.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_035726422.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_035740852.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_035730176.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035718621.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_035724312.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_035734674.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035738160.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_035731861.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_035729863.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035727869.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035723256.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_035742149.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_035724692.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035743496.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_035732298.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_035724741.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553	"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs"
XP_035720379.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035735317.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_035739860.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-69481	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Degradation of DVL";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints"
XP_035736934.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035724689.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035722639.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035734999.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148	"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035737143.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_035729581.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_035731583.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_035726679.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLI"
XP_035725354.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_035728197.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035743459.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_035739149.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_035721859.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_035733307.1	26	Reactome: R-HSA-5621575;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722	"CD209 (DC-SIGN) signaling";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex"
XP_035723299.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_035724727.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035728601.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_035720740.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_035729491.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_035732002.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857	"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation"
XP_035734956.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_035725637.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035740533.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_035727140.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_035741250.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035734524.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035743890.1	8	MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168	"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_035736972.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035717263.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_035727126.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035730405.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035732319.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_035739111.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035724445.1	5	Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_035732833.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035742239.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035741779.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Ub-specific processing proteases"
XP_035737663.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_035739669.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-6804756	"Activation of AMPK downstream of NMDARs";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation"
XP_035738811.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035743656.1	4	MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_035722830.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_035742988.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_035724880.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_035724596.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035727987.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035742076.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035729795.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_035731444.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_035737233.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_035724486.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035729651.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035717328.1	2	Reactome: R-HSA-83936;Reactome: R-HSA-2564830	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Cytosolic iron-sulfur cluster assembly"
XP_035744173.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_035731077.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035728454.1	8	Reactome: R-HSA-373080;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-5340588;Reactome: R-HSA-4608870;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263;Reactome: R-HSA-4086398	"Class B/2 (Secretin family receptors)";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Asymmetric localization of PCP proteins";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Ca2+ pathway"
XP_035724825.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;Reactome: R-HSA-1475029	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide"
XP_035725838.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035725414.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_035729318.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740378.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035719893.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035731306.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_035722893.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035738221.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6679	"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Propanoate metabolism";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis"
XP_035732545.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_035736940.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035731214.1	9	Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035742307.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035743974.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_035732459.1	6	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling"
XP_035718193.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_035740721.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_035723863.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_035727172.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035722148.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035741463.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_035742735.1	10	Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-201688	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Signal transduction by L1";"WNT mediated activation of DVL"
XP_035739268.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035741587.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035719461.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_035739638.1	13	Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-3000178;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157	"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen degradation";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Collagen chain trimerization";"Signaling by PDGF";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"ECM proteoglycans";"Anchoring fibril formation";"Laminin interactions"
XP_035735898.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035735851.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035718664.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_035727354.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035729282.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_035743298.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035727293.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035736714.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035735457.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_035743932.1	5	KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Neutrophil degranulation"
XP_035723581.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_035743251.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_035727134.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_035740953.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035740102.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_035722461.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_035738260.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035736680.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_035732843.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035720099.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035728475.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_035717197.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane"
XP_035725664.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_035738313.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_035723565.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_035735606.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_035727571.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035734014.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_035732331.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035718126.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035728263.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035731579.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_035718140.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035730671.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_035722826.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_035737243.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_035724057.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_035738309.1	10	KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05170+2.7.1.153	"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection";"mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Human immunodeficiency virus 1 infection"
XP_035739249.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_035718869.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_035720056.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035722420.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035725848.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_035717163.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_035736728.1	5	KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527	"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation"
XP_035719169.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_035734670.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035738667.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_035735978.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408	"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase"
XP_035721922.1	3	MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_035720910.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_035722391.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_035739512.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035726019.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035731629.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035741971.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035742403.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_035722138.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_035735045.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_035742745.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_035722216.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035718244.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035739419.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_035730521.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_035734585.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_035730913.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035728690.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035735133.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_035726003.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_035729400.1	7	Reactome: R-HSA-6782315;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716	"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035725350.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_035724911.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168	"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035720602.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035736000.1	13	MetaCyc: PWY-2261;MetaCyc: PWY-7533;MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-6370	"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)"
XP_035743801.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_035741208.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_035743942.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035733139.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_035739403.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_035721401.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_035737409.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_035741254.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_035730909.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_035730276.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_035734277.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_035734603.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035741004.1	4	KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_035719067.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035718530.1	2	Reactome: R-HSA-3785653;Reactome: R-HSA-3322077	"Myoclonic epilepsy of Lafora";"Glycogen synthesis"
XP_035733212.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_035741972.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035743665.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035724339.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Non-integrin membrane-ECM interactions"
XP_035729946.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035722392.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_035739511.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035729769.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_035724159.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-164378	"DARPP-32 events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling"
XP_035735098.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_035730160.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases"
XP_035734448.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_035738405.1	7	MetaCyc: PWY-7818;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis"
XP_035723063.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035731750.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_035725676.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_035738743.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_035739695.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_035743802.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_035741934.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035740243.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035718048.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_035743941.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035733388.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_035737594.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-176412	"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C"
XP_035724912.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-141430	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_035724196.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035725069.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_035720197.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_035736657.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_035731877.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035730672.1	14	MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1	"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism"
XP_035720314.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035724025.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035725038.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035718483.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035734382.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035718593.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_035732332.1	4	Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism"
XP_035722900.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035719548.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035724207.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes"
XP_035740413.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035729473.1	4	KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_035730264.1	6	Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-174437	"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand"
XP_035727479.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_035720206.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035735917.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035743739.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_035725526.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_035733907.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Estrogen-dependent gene expression";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_035730634.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035732374.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035736372.1	11	KEGG: 00240+6.3.5.5;Reactome: R-HSA-500753;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7790;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism"
XP_035726614.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_035724368.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_035737737.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_035739876.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_035743094.1	30	Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075	"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_035726780.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_035727016.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035727171.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035729936.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035736800.1	12	KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-6803	"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing"
XP_035738222.1	17	Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2	"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Glyoxylate assimilation";"Pyruvate metabolism";"Fatty acid biosynthesis";"Propanoate metabolism";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes"
XP_035735764.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035719195.1	20	Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210	"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_035743286.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_035717487.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035734438.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_035721007.1	9	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035736783.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_035718895.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_035740663.1	6	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_035720771.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035717597.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035725567.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_035718038.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_035740233.1	5	KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism"
XP_035743931.1	5	KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6	"Purine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism"
XP_035741944.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_035741550.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_035721280.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035730839.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_035743252.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_035734773.1	8	Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Regulation of PTEN localization";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_035725593.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_035717563.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035740194.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035735852.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_035735480.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_035726819.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035720065.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035726464.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035722538.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_035721960.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035732342.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035718676.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_035738812.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035721729.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-165159	"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"mTOR signalling"
XP_035738564.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035730868.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035729686.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_035732355.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035725975.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_035720450.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_035721376.1	13	Reactome: R-HSA-1660662;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.23	"Glycosphingolipid metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B";"Other glycan degradation";"Sialic acid metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_035734146.1	4	KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;MetaCyc: PWY-5874;Reactome: R-HSA-917937	"Porphyrin and chlorophyll metabolism";"Heme degradation";"Heme degradation I";"Iron uptake and transport"
XP_035729652.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035730147.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_035743749.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_035722040.1	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_035726229.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035728793.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_035717772.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-674695	"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events"
XP_035737953.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs"
XP_035742112.1	9	MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590	"Gliotoxin biosynthesis";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Glutathione conjugation"
XP_035732043.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_035720899.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_035726578.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035736208.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_035737764.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_035734079.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035724755.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035725016.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035739568.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_035724658.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_035721717.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035734666.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_035724742.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_035731862.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_035737425.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035724691.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035720106.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035729599.1	12	KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25	"Monobactam biosynthesis";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Selenocompound metabolism";"Sulfite oxidation III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Transport and synthesis of PAPS";"Purine metabolism"
XP_035736971.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035740776.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035731754.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_035727593.1	11	Reactome: R-HSA-9008059;Reactome: R-HSA-432142;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-389948;Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-912694;Reactome: R-HSA-512988	"Interleukin-37 signaling";"Platelet sensitization by LDL";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"PD-1 signaling";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"PECAM1 interactions";"Regulation of IFNA signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_035741930.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035734236.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035724515.1	11	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_035732286.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035729489.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_035723006.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_035728744.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035728602.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_035729492.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_035721557.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_035732001.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_035729582.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation"
XP_035733996.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_035738671.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_035732681.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_035720310.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035734631.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_035741728.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035736609.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035742432.1	7	MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_035718797.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_035732966.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035722904.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035719958.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_035726902.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035719904.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_035727975.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035726074.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_035719072.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_035740035.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_035719991.1	4	KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_035730260.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035735721.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_035718622.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-8854214	"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs"
XP_035736613.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035717379.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_035743355.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035724311.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_035722034.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035730012.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_035727530.1	8	Reactome: R-HSA-6787639;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5739;MetaCyc: PWY-7573;MetaCyc: PWY-66	"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)"
XP_035742474.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_035733959.1	10	Reactome: R-HSA-977225;Reactome: R-HSA-2453864;MetaCyc: PWY-7849;MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902	"Amyloid fiber formation";"Retinoid cycle disease events";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Neutrophil degranulation";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)"
XP_035738068.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_035720633.1	7	Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-201681	"WNT mediated activation of DVL";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"PCP/CE pathway";"TCF dependent signaling in response to WNT"
XP_035743135.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035735747.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035720297.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_035718763.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035719034.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_035735953.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_035721023.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_035744158.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_035744104.1	4	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neddylation";"Downregulation of ERBB2:ERBB3 signaling"
XP_035738049.1	17	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7187	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_035729097.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_035744191.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035718544.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_035730221.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035731775.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_035723946.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_035737098.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_035717793.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_035719799.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_035736497.1	4	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis"
XP_035724732.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035741554.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035741940.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_035721284.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035741508.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_035730247.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9010553	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs"
XP_035741926.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035736275.1	18	MetaCyc: PWY-7117;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6638	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Tyrosine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III"
XP_035733695.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_035731061.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_035717506.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035725572.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035727271.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035742442.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_035744200.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-5381;MetaCyc: PWY-6596;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-7821;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5	"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"Adenosine nucleotides degradation I";"Pyrimidine metabolism";"Purine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism"
XP_035729918.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035726343.1	10	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Regulation of TNFR1 signaling";"T cell receptor signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035743919.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035731528.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035727038.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035719295.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_035739037.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_035742549.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-400206	"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha"
XP_035725479.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_035724809.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035740045.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_035737917.1	7	Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539	"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate and glutamine metabolism"
XP_035723265.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035739822.1	5	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Purine metabolism"
XP_035723635.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_035743903.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_035739442.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_035722871.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_035734627.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035726055.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_035728597.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_035720643.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035735305.1	24	Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-202424;Reactome: R-HSA-5218921	"RHO GTPases activate PKNs";"Integrin signaling";"FCERI mediated NF-kB activation";"Activation of AKT2";"Relaxin signaling pathway";"RSK activation";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"mTOR signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation"
XP_035739455.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade"
XP_035740086.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035725758.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_035741985.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_035725642.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_035735766.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_035726915.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase"
XP_035722510.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_035743096.1	30	Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075	"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_035740159.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035727014.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_035733757.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_035730241.1	29	Reactome: R-HSA-69541;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-6803207;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-6804760;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942	"Stabilization of p53";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)"
XP_035733943.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035735884.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_035731389.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035729934.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035737435.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_035731392.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035736863.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035723940.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_035744163.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035740339.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport"
XP_035725655.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035735949.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle"
XP_035723508.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_035731067.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_035727670.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_035740196.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035718999.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_035744197.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_035741946.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035730227.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_035729091.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_035717500.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035718982.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_035726466.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271	"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_035739679.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_035732753.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_035736458.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_035732509.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation"
XP_035719750.1	12	MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism"
XP_035723714.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035734375.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035728887.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_035724413.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_035719471.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_035726323.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_035738142.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035730685.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035738707.1	11	Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-1268020;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-5628897	"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes"
XP_035742529.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_035736346.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035742031.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation"
XP_035738155.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_035741635.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_035719877.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_035743180.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_035733476.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035742278.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_035739842.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination"
XP_035728504.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035736320.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_035738566.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_035727277.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035741265.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_035739422.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_035730646.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_035731612.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035725879.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_035734144.1	5	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_035730620.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035730411.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_035726022.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_035740080.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180910	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs"
XP_035737523.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035741473.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_035723873.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_035728718.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_035730103.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_035732225.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_035729944.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035733933.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_035718879.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_035724663.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_035743557.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035730078.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_035723930.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035732007.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_035727883.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035743888.1	8	Reactome: R-HSA-191273;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34	"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
XP_035720100.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035735013.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035735939.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_035737703.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_035717173.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_035720659.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_035721598.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_035728916.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035737445.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_035741936.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_035738270.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_035733178.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035732280.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_035737825.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035734230.1	6	KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599	"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate"
XP_035726359.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_035725177.1	12	MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9	"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions"
XP_035719283.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_035725674.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_035735312.1	24	KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Activation of AKT2";"RHO GTPases activate PKNs";"Integrin signaling";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"RSK activation";"Thermogenesis";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_035722283.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_035742553.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_035731569.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_035721711.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_035737596.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_035734987.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_035726139.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035724194.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035742709.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_035724317.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_035721342.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_035727028.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_035731538.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_035732960.1	5	Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-209543	"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes"
XP_035723680.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_035719963.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_035726168.1	13	MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757	"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines"
XP_035738345.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_035739205.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035720316.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_035741652.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_035717969.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035741645.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_035722963.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_035735692.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_035734267.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_035720291.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_035737215.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035722997.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_035732376.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035717688.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_035725524.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035734293.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_035742205.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_035723728.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_035727365.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_035741377.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_035742027.1	11	Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170660	"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway"
XP_035736182.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_035739041.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_035740658.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_035718546.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_035727632.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569	"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_035726786.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_035727010.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway"
XP_035735452.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_035723889.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684	"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog 'on' state"
XP_035729930.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_035744106.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035735880.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_035718277.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_035729287.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_035735445.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_035738255.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_035739933.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_035723944.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_035722862.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_035735559.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_035719514.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_035727177.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035741165.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035729000.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_035727674.1	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_035721286.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_035741556.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_035730574.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_035742302.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_035738878.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035734244.1	3	Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60	"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation"
XP_035721001.1	9	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_035729575.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_035739003.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_035717504.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_035724776.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035719754.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_035735719.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_035725561.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_035727262.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_035729993.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_035731072.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_035739683.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock"
XP_035720499.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035733832.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785	"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome"
XP_035740259.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_035728075.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_035718670.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_035730141.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_035730853.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_035731958.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_035725028.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_035734414.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_035719085.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_035744263.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_035720850.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035727982.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_035728500.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_035743687.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035724457.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_035735215.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_035734140.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_035721370.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_035729967.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_035742990.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_035740084.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_035724898.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539	"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_035732023.1	17	Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-202424;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091	"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downstream TCR signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells"
XP_035721415.1	5	Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_035729508.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_035720338.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_035731799.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_035734272.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_035738951.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-6978	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II"
XP_035729940.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_035728688.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_035743753.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035719775.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035727655.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_035736318.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_035739943.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_035737949.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_035720104.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035722775.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_035734167.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035735435.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_035741063.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_035720191.1	6	MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497	"Guanosine nucleotides degradation II";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)"
XP_035724606.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_035730618.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_035728969.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_035737115.1	6	Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66	"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_035743921.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_035733679.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_035726735.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_035740774.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_035725670.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_035739517.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Activation of the pre-replicative complex"
XP_035742943.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_035735673.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035730715.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_035723004.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_035736282.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_035730203.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_035728289.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035725495.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_035722906.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_035733994.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_035722528.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_035725585.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_035726076.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_035742870.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163	"Protein ubiquitination";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway"
XP_035730351.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_035728292.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_035721739.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_035717273.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_035730398.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_035719906.1	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;Reactome: R-HSA-947581;MetaCyc: PWY-7887	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_035737731.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_035720087.1	4	KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_035732180.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_035727879.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_035730219.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha"
XP_035722036.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_035717916.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;MetaCyc: PWY-7511	"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination"
XP_035724133.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_035720369.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144	"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_035724201.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_035734350.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_035717192.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_035735911.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_035728054.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_035718883.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"