Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_028896638.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_011196397.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_011195964.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028897050.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028893560.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_011187961.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889 "CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes" XP_028901025.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_011190190.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011180967.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011182275.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011192953.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028894606.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011183818.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_011189083.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174084 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_011187515.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011191031.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011194742.1 24 Reactome: R-HSA-5610783;Reactome: R-HSA-164378;Reactome: R-HSA-111931;Reactome: R-HSA-5610787;Reactome: R-HSA-163358;Reactome: R-HSA-983231;Reactome: R-HSA-422356;Reactome: R-HSA-5610780;Reactome: R-HSA-392517;Reactome: R-HSA-9634600;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-442720;Reactome: R-HSA-8963896;Reactome: R-HSA-9010642;Reactome: R-HSA-163615;KEGG: 04150+2.7.11.11;Reactome: R-HSA-381676;Reactome: R-HSA-5610785;Reactome: R-HSA-8853659;Reactome: R-HSA-5621575;Reactome: R-HSA-163560;Reactome: R-HSA-180024 "Degradation of GLI2 by the proteasome";"PKA activation in glucagon signalling";"PKA-mediated phosphorylation of CREB";"Hedgehog 'off' state";"PKA-mediated phosphorylation of key metabolic factors";"Factors involved in megakaryocyte development and platelet production";"Regulation of insulin secretion";"Degradation of GLI1 by the proteasome";"Rap1 signalling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"HDL assembly";"ROBO receptors bind AKAP5";"PKA activation";"mTOR signaling pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"GLI3 is processed to GLI3R by the proteasome";"RET signaling";"CD209 (DC-SIGN) signaling";"Triglyceride catabolism";"DARPP-32 events" XP_011182879.1 29 MetaCyc: PWY-3162;MetaCyc: PWY-6333;MetaCyc: PWY-5082;MetaCyc: PWY-6587;MetaCyc: PWY-6802;MetaCyc: PWY-5057;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5751;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5079;MetaCyc: PWY-6871;MetaCyc: PWY-7396;KEGG: 00260+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-7111 "L-tryptophan degradation V (side chain pathway)";"Acetaldehyde biosynthesis I";"L-methionine degradation III";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis";"L-valine degradation II";"Tyrosine metabolism";"Pyruvate fermentation to ethanol I";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Retinol metabolism";"Fatty acid degradation";"L-isoleucine degradation II";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol II";"Chloroalkane and chloroalkene degradation";"Serotonin degradation";"Phenylethanol biosynthesis";"Naphthalene degradation";"(S)-propane-1,2-diol degradation";"Metabolism of xenobiotics by cytochrome P450";"Noradrenaline and adrenaline degradation";"L-phenylalanine degradation III";"3-methylbutanol biosynthesis (engineered)";"Butanol and isobutanol biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"alpha-Linolenic acid metabolism";"L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)" XP_011180877.1 5 MetaCyc: PWY-7766;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_011176973.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011178333.2 13 MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-561 "Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_011188565.2 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_011186386.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011190465.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" XP_011185942.2 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_011185023.1 7 KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;MetaCyc: PWY-6352 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis" XP_028898437.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_028898686.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_011184038.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_011181857.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_011181074.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011180505.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis" XP_028893569.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011183941.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028900743.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_011187835.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028895783.1 11 Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660 "Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway" XP_011183094.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011191112.1 13 Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-380972 "Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_011184623.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011179527.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011184362.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_011185765.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028901891.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011192511.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_028898844.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011188119.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_028901834.1 7 MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183 "Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_011187261.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011187323.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_011188884.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_028897152.1 7 MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67 "3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system" XP_011187836.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028896402.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028894699.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_028894348.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_011178189.1 4 MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072 "Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization" XP_011179646.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73762 "RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation" XP_011182285.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011190054.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_011193541.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_028897712.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_011187103.1 11 Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-3214847 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome";"Ub-specific processing proteases";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones" XP_011185096.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" XP_011185077.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028900833.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011193875.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011177964.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011187248.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011184047.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_011189054.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011184615.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_011176805.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_011193401.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210 "G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_011176563.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_011178123.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011184423.1 15 Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568 "DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_028898997.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_011184799.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028898641.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011184202.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476 "TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1" XP_028895866.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403 "Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling" XP_011180684.2 3 Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation" XP_028896374.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011188169.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_011179057.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011182997.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_011180484.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Signaling by Hippo" XP_028898711.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011180123.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_028898484.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_011187253.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011187643.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011196889.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186079.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011195428.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899405.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_011192095.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_028893839.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011188885.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011185607.1 8 MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle" XP_011194393.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_011187734.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011183679.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_028900178.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011183356.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028893608.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_028900574.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011187208.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011184440.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_011183390.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_011179969.1 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" XP_011192245.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_011178479.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011193444.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_011194369.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011193094.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733 "NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_011190728.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_011188709.2 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_011193519.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011185542.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_011195936.1 7 KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456 "Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria" XP_028898050.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011178152.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028897060.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011192458.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_028895920.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_011179978.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028901833.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028897054.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011192802.1 10 MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055 "CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis" XP_011180993.1 15 KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7383 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Glycolysis";"Pyruvate metabolism";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_028901383.1 12 Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72702 "Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition" XP_011179883.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011183419.2 10 MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2 "Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism" XP_028894797.1 8 KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5173105 "Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation" XP_028897670.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_028896297.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_011183643.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011194485.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_011190014.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_011176998.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_028901262.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011196061.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51 "Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism" XP_011196564.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011177710.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-140875 "Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation" XP_028901757.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_028898071.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_028894178.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_028902221.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011190878.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_011178851.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_028897387.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011196663.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011191768.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011179602.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_011195241.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011179912.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011189134.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_011182904.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_011192259.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_028901836.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011196022.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011196203.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011179920.1 14 MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-181;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622 "Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Cyanoamino acid metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)" XP_011192198.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_011190423.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011190919.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011181765.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_011190604.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" XP_011188375.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_011196417.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_011179255.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_011193764.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_028899646.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_028900927.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_028901636.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_011190687.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028895812.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011182757.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011196310.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011189180.1 14 MetaCyc: PWY-5078;MetaCyc: PWY-5101;MetaCyc: PWY-5104;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5103;MetaCyc: PWY-5076;Reactome: R-HSA-70895;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767 "L-isoleucine degradation II";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"L-leucine degradation III";"Branched-chain amino acid catabolism";"Glucosinolate biosynthesis";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)" XP_011183605.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_028898893.1 6 KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_011178471.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011180569.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028899764.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_011187674.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_011178507.1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709 "N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins" XP_011193199.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_011183308.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_011183528.1 5 Reactome: R-HSA-936440;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233 "Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway" XP_028894218.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028897714.1 4 Reactome: R-HSA-112311;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Synthesis of PC" XP_011185618.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_028895322.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011191841.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899296.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_028896093.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_011192146.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011181708.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695 "Signal transduction by L1";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation" XP_011193154.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_011192638.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011186611.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011184534.1 5 Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225 "Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_011192512.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011194528.1 8 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_028899907.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_011194918.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51 "Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism" XP_011183932.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" XP_011178451.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011177711.1 6 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_011190365.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_028901942.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation" XP_028901118.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011181633.1 11 Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-1268020;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-3299685 "Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Mitochondrial protein import";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species" XP_028899378.1 4 KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558 "Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine" XP_011179314.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_028900784.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_028900466.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011187974.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_028895534.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_011194958.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_028899285.1 12 Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13 "Glycolysis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis" XP_011180810.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011196437.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_028900533.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_028898308.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788 "Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC" XP_011178153.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011192575.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_011193560.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_028898009.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_011195443.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011178827.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_011194733.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011184416.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_011179159.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011183718.1 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-6798695 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Neutrophil degranulation" XP_011179147.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_011183733.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011178981.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_028895086.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_011193543.1 31 MetaCyc: PWY-7746;MetaCyc: PWY-7858;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-7723;MetaCyc: PWY-6113;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-5971;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-7664;Reactome: R-HSA-75105;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-6519;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-6799;Reactome: R-HSA-199220;Reactome: R-HSA-163765;MetaCyc: PWY-5989 "Mycobacterial sulfolipid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Bacterial bioluminescence";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acyl-CoA biosynthesis";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)" XP_028901755.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_011186890.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_011184461.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_028897623.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011194954.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_028900998.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-201722 "NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex" XP_011184622.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011179157.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_011188470.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_011189066.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry" XP_011176943.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_028894159.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_028895788.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011177429.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_028899784.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_011195710.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_028897902.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028894117.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011179113.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_028899794.1 18 MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Linoleic acid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_028897640.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_028900738.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_028899762.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_011183820.1 5 Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_011186765.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_011179603.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-373753 "COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Nephrin family interactions" XP_028897545.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_028898466.1 7 KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_028896962.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_028901134.1 12 MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I" XP_011178990.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_011181252.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028900855.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011194221.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_011179641.2 13 Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_011189804.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028898853.1 14 Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402 "Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex" XP_011192272.1 4 KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism" XP_011178740.2 4 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis" XP_011178050.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011194588.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011181964.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_028894123.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011188564.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_011185644.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism" XP_011191356.1 3 Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_011182708.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_028893645.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444 "T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011197050.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_011191208.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" XP_011196149.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_011193190.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_028897702.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_028894265.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011195055.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_028901471.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins" XP_028897791.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011197061.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011194573.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_028900839.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011183535.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_028901431.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_011192879.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_011190122.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028899633.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_011178934.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181277.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011196054.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_011188260.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_011185094.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011180467.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011181320.1 16 Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1236394;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-1250347;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-1251985;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1963640 "SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"Nuclear signaling by ERBB4";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"GRB2 events in ERBB2 signaling" XP_011192063.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878 "Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport" XP_011179143.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028896280.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011192248.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011179671.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_011189188.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011187006.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_011190796.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_028899505.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_028897125.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011185570.1 10 Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953 "HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation" XP_011185651.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_011182465.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_028894355.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011179915.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" XP_011192520.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_011192217.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_011194195.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_011193759.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_011193183.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-8950505 "BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_028896342.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011190873.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_011183886.1 179 Reactome: R-HSA-2559585;Reactome: R-HSA-5696395;Reactome: R-HSA-168927;Reactome: R-HSA-901032;Reactome: R-HSA-8856825;Reactome: R-HSA-1236382;Reactome: R-HSA-2565942;Reactome: R-HSA-1358803;Reactome: R-HSA-180585;Reactome: R-HSA-937039;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-110312;Reactome: R-HSA-532668;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-174154;Reactome: R-HSA-168928;Reactome: R-HSA-5658442;Reactome: R-HSA-5656169;Reactome: R-HSA-8948747;Reactome: R-HSA-5654727;Reactome: R-HSA-2173795;Reactome: R-HSA-2173791;Reactome: R-HSA-174048;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-1295596;Reactome: R-HSA-9613829;Reactome: R-HSA-9010553;Reactome: R-HSA-3134975;Reactome: R-HSA-937072;Reactome: R-HSA-5357905;Reactome: R-HSA-2467813;Reactome: R-HSA-5696394;Reactome: R-HSA-2559580;Reactome: R-HSA-5656121;Reactome: R-HSA-9013507;Reactome: R-HSA-175474;Reactome: R-HSA-5676590;Reactome: R-HSA-1253288;Reactome: R-HSA-8876493;Reactome: R-HSA-5693565;Reactome: R-HSA-156902;Reactome: R-HSA-8948751;Reactome: R-HSA-2644606;Reactome: R-HSA-179409;Reactome: R-HSA-9014325;Reactome: R-HSA-9636383;Reactome: R-HSA-5654726;Reactome: R-HSA-211733;Reactome: R-HSA-72706;Reactome: R-HSA-983168;Reactome: R-HSA-192823;Reactome: R-HSA-201681;Reactome: R-HSA-5696397;Reactome: R-HSA-162588;Reactome: R-HSA-2672351;Reactome: R-HSA-174113;Reactome: R-HSA-72689;Reactome: R-HSA-5693607;Reactome: R-HSA-174490;Reactome: R-HSA-75815;Reactome: R-HSA-9013973;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-6791226;Reactome: R-HSA-3785653;Reactome: R-HSA-5654732;Reactome: R-HSA-937042;Reactome: R-HSA-8939902;Reactome: R-HSA-5675221;Reactome: R-HSA-9604323;Reactome: R-HSA-1169408;Reactome: R-HSA-5655862;Reactome: R-HSA-8875360;Reactome: R-HSA-8849469;Reactome: R-HSA-2979096;Reactome: R-HSA-6782135;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-450321;Reactome: R-HSA-195253;Reactome: R-HSA-168638;Reactome: R-HSA-5654733;Reactome: R-HSA-205043;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-975144;Reactome: R-HSA-2173788;Reactome: R-HSA-5675482;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-6804757;Reactome: R-HSA-977225;Reactome: R-HSA-917937;Reactome: R-HSA-2871837;Reactome: R-HSA-975957;Reactome: R-HSA-9646399;Reactome: R-HSA-6783310;Reactome: R-HSA-4641258;Reactome: R-HSA-5696400;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-4641263;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-6804760;Reactome: R-HSA-174084;Reactome: R-HSA-936964;Reactome: R-HSA-2173796;Reactome: R-HSA-8866652;Reactome: R-HSA-110320;Reactome: R-HSA-1799339;Reactome: R-HSA-5689901;Reactome: R-HSA-68827;Reactome: R-HSA-9633012;Reactome: R-HSA-8941858;Reactome: R-HSA-975956;Reactome: R-HSA-400253;Reactome: R-HSA-917729;Reactome: R-HSA-975110;Reactome: R-HSA-912631;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-69541;Reactome: R-HSA-2894862;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-9645460;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-3769402;Reactome: R-HSA-187577;Reactome: R-HSA-5685942;Reactome: R-HSA-2408557;Reactome: R-HSA-5689877;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-4608870;Reactome: R-HSA-3322077;Reactome: R-HSA-445989;Reactome: R-HSA-6782210;Reactome: R-HSA-5607761;Reactome: R-HSA-450302;Reactome: R-HSA-6804756;Reactome: R-HSA-156827;Reactome: R-HSA-182971;Reactome: R-HSA-5357956;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-936440;Reactome: R-HSA-5689896;Reactome: R-HSA-110314;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-209560;Reactome: R-HSA-937041;Reactome: R-HSA-2122948;Reactome: R-HSA-5205685;Reactome: R-HSA-975163;Reactome: R-HSA-1236974;Reactome: R-HSA-8863795;Reactome: R-HSA-9615710;Reactome: R-HSA-209543;Reactome: R-HSA-9033241;Reactome: R-HSA-8854050;Reactome: R-HSA-6781823;Reactome: R-HSA-180534;Reactome: R-HSA-6781827;Reactome: R-HSA-72764;Reactome: R-HSA-174178;Reactome: R-HSA-2691232;Reactome: R-HSA-8866654;Reactome: R-HSA-69231;Reactome: R-HSA-5362768;Reactome: R-HSA-9637628;Reactome: R-HSA-2122947 "Oncogene Induced Senescence";"Formation of Incision Complex in GG-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"ER Quality Control Compartment (ERQC)";"Cargo recognition for clathrin-mediated endocytosis";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of PLK1 Activity at G2/M Transition";"Downregulation of ERBB2:ERBB3 signaling";"Vif-mediated degradation of APOBEC3G";"IRAK1 recruits IKK complex";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translesion synthesis by REV1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"APC/C:Cdc20 mediated degradation of Securin";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of RAS by GAPs";"Termination of translesion DNA synthesis";"Regulation of PTEN localization";"Negative regulation of FGFR2 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Spry regulation of FGF signaling";"Chaperone Mediated Autophagy";"Regulation of expression of SLITs and ROBOs";"Regulation of innate immune responses to cytosolic DNA";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of TNFR1 signaling";"Separation of Sister Chromatids";"DNA Damage Recognition in GG-NER";"Oxidative Stress Induced Senescence";"Translesion synthesis by POLI";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Assembly Of The HIV Virion";"NIK-->noncanonical NF-kB signaling";"Downregulation of ERBB4 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Peptide chain elongation";"Regulation of PTEN stability and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"APC-Cdc20 mediated degradation of Nek2A";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of FGFR1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Antigen processing: Ubiquitination & Proteasome degradation";"Viral mRNA Translation";"TCF dependent signaling in response to WNT";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Budding and maturation of HIV virion";"Stimuli-sensing channels";"SCF-beta-TrCP mediated degradation of Emi1";"Formation of a pool of free 40S subunits";"Processing of DNA double-strand break ends";"Membrane binding and targetting of GAG proteins";"Ubiquitin-dependent degradation of Cyclin D";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Myoclonic epilepsy of Lafora";"Negative regulation of FGFR3 signaling";"IRAK2 mediated activation of TAK1 complex";"Regulation of RUNX2 expression and activity";"Negative regulation of MAPK pathway";"Negative regulation of NOTCH4 signaling";"ISG15 antiviral mechanism";"Translesion synthesis by POLK";"InlB-mediated entry of Listeria monocytogenes into host cell";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Dual incision in TC-NER";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of beta-catenin by the destruction complex";"NOD1/2 Signaling Pathway";"Negative regulation of FGFR4 signaling";"NRIF signals cell death from the nucleus";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Downregulation of TGF-beta receptor signaling";"Regulation of necroptotic cell death";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Regulation of TP53 Degradation";"Amyloid fiber formation";"Iron uptake and transport";"FCERI mediated NF-kB activation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Aggrephagy";"Fanconi Anemia Pathway";"Degradation of DVL";"Dual Incision in GG-NER";"UCH proteinases";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of FZD by ubiquitination";"G2/M Checkpoints";"Degradation of AXIN";"Regulation of TP53 Activity through Methylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Translesion Synthesis by POLH";"SRP-dependent cotranslational protein targeting to membrane";"Metalloprotease DUBs";"CDT1 association with the CDC6:ORC:origin complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of RUNX3 expression and activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Circadian Clock";"Endosomal Sorting Complex Required For Transport (ESCRT)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of signaling by CBL";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Stabilization of p53";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neddylation";"Defective CFTR causes cystic fibrosis";"Alpha-protein kinase 1 signaling pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Deactivation of the beta-catenin transactivating complex";"SCF(Skp2)-mediated degradation of p27/p21";"HDR through Homologous Recombination (HRR)";"Selenocysteine synthesis";"Josephin domain DUBs";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Asymmetric localization of PCP proteins";"Glycogen synthesis";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dectin-1 mediated noncanonical NF-kB signaling";"activated TAK1 mediates p38 MAPK activation";"Regulation of TP53 Activity through Phosphorylation";"L13a-mediated translational silencing of Ceruloplasmin expression";"EGFR downregulation";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases";"Recognition of DNA damage by PCNA-containing replication complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"NF-kB is activated and signals survival";"IKK complex recruitment mediated by RIP1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Pink/Parkin Mediated Mitophagy";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"ER-Phagosome pathway";"Downregulation of ERBB2 signaling";"Late endosomal microautophagy";"p75NTR recruits signalling complexes";"Peroxisomal protein import";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Formation of TC-NER Pre-Incision Complex";"Vpu mediated degradation of CD4";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Eukaryotic Translation Termination";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"Cyclin D associated events in G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Modulation by Mtb of host immune system";"NOTCH1 Intracellular Domain Regulates Transcription" XP_011187441.1 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" XP_011187087.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011178263.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_011196664.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_011183436.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_028901848.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_011192528.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_028896420.1 14 KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6728;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7279 "Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)" XP_011195425.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_011185529.1 2 KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_011187346.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_011192188.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_011196932.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_028893631.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_028893885.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011191647.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_011196467.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_011196532.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_011181528.1 10 MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524 "Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis";"PPARA activates gene expression";"Butanoate metabolism";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)" XP_011179430.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_028901414.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_028896366.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011185569.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events" XP_011193738.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011190185.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011181705.1 7 Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-114608 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation" XP_011182163.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028901013.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_028899399.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex" XP_011194687.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_011197146.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_011192072.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011195604.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028899619.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_011183136.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_011188625.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_011184301.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_028893488.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_011191719.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_011185566.1 4 MetaCyc: PWY-5874;Reactome: R-HSA-917937;Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18 "Heme degradation I";"Iron uptake and transport";"Heme degradation";"Porphyrin and chlorophyll metabolism" XP_028896724.1 13 Reactome: R-HSA-4085001;Reactome: R-HSA-2024096;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;KEGG: 00052+3.2.1.23;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23 "Sialic acid metabolism";"HS-GAG degradation";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Galactose metabolism";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sphingolipid metabolism" XP_011194287.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011190189.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011180426.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011182489.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_011190581.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011176525.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_028898563.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_028896303.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_028894698.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_028895663.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-432040 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_028899094.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_011177301.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_011184561.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105 "Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation" XP_028896764.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011187560.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_011194865.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011188903.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011192194.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_028895475.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_011190398.1 57 Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764 "UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Neutrophil degranulation";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling" XP_011196433.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_011189672.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028894259.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_028900792.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_028899756.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_011181711.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695 "Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation" XP_011195130.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_028900490.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011178148.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_011180419.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_028897053.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011183027.1 2 MetaCyc: PWY-6938;Reactome: R-HSA-430039 "NADH repair";"mRNA decay by 5' to 3' exoribonuclease" XP_028900181.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_011192818.1 16 Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-164939;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295 "EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Nef mediated downregulation of CD28 cell surface expression";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation" XP_011196957.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011184092.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733 "NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_011188115.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_011177978.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_028896357.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_028900931.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_011181853.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_011180571.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011192112.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_011182560.1 6 KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_028898364.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_011193398.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_011189300.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_011178712.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_011193257.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_028898868.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_028898156.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_011189458.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_011190532.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_011185927.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_011177065.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_011189990.1 23 Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-4086398 "ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Ca2+ pathway" XP_011196158.1 12 KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Stachyose degradation" XP_011177723.1 14 MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_011189984.1 23 Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-4086398 "ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway" XP_011177536.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_011194859.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011194626.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011196830.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895595.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_011181149.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_011181406.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_028893470.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011184861.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_028900404.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011179865.1 40 Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_028894144.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011185467.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis" XP_011177010.1 4 KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841 "Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_011185015.1 8 MetaCyc: PWY-8086;MetaCyc: PWY-5481;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism" XP_011179111.1 19 MetaCyc: PWY-6545;Reactome: R-HSA-380270;MetaCyc: PWY-7226;MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7176 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis" XP_011187530.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011187045.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011196935.1 7 Reactome: R-HSA-69205;MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3 "G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_011182183.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_028894381.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" XP_028900796.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_011189301.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_011191791.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011178528.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_028898480.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_011188906.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation" XP_011189940.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_028897753.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_011176818.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_011184777.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_028894121.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011195015.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_028893790.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_011192581.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_011195962.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_011195011.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_011188744.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011187586.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_011195736.1 9 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_028899895.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011177750.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_011197020.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011176480.1 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_028899111.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011196714.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_011196197.1 5 Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-162710 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011176918.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_028899183.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_011176700.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028898017.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_011177391.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028900542.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_028899887.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011181638.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport" XP_011187700.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_011195953.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_011178580.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011186968.2 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_011181486.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_011194927.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_011196819.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028897790.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011184940.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011188856.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011179678.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_011192905.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011188926.1 3 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III" XP_028900003.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011196886.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028900808.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_011190257.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028899600.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011193066.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801 "Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD" XP_028894115.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_011184208.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028893584.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011192180.1 19 MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;MetaCyc: PWY-8086;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-1622 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Methane metabolism";"Pyruvate metabolism";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)" XP_028895803.1 17 Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-4086398 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway" XP_011182030.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_028898257.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_011180923.1 11 MetaCyc: PWY-6174;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-922;MetaCyc: PWY-7102;MetaCyc: PWY-6859;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-5123;Reactome: R-HSA-191273 "Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway I";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis" XP_011184567.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_011187862.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_011184081.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_011181307.1 15 Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_028901995.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166 "Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade" XP_028898632.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_028894307.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_028899825.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_011184080.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028896185.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_011196531.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_011194711.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_028899342.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011180003.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028900453.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_011176737.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011186403.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes" XP_011180360.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_011192906.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_028895743.1 6 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_011184075.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011186669.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_011190171.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_011193134.1 8 MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Synthesis of PG";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_011178466.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_028899305.1 5 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)" XP_011193021.1 3 Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129 "Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)" XP_011180747.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011184317.1 3 Reactome: R-HSA-5173214;Reactome: R-HSA-189085;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Digestion of dietary carbohydrate";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028900922.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism" XP_011177733.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_011189027.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028893865.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011191386.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011192938.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_028894443.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011194932.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_011180362.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_028897115.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_011177162.1 6 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-416993 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors" XP_028900827.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011182070.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011180753.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011192392.1 83 Reactome: R-HSA-389359;Reactome: R-HSA-5654706;Reactome: R-HSA-2428933;Reactome: R-HSA-8851805;Reactome: R-HSA-5654695;Reactome: R-HSA-2424491;Reactome: R-HSA-9634285;Reactome: R-HSA-5654726;Reactome: R-HSA-5654700;Reactome: R-HSA-2029482;Reactome: R-HSA-2179392;Reactome: R-HSA-182971;Reactome: R-HSA-5654704;Reactome: R-HSA-210993;Reactome: R-HSA-5654732;Reactome: R-HSA-5655302;Reactome: R-HSA-391160;Reactome: R-HSA-8875555;Reactome: R-HSA-5654733;Reactome: R-HSA-8853334;Reactome: R-HSA-5655253;Reactome: R-HSA-5663213;Reactome: R-HSA-2219530;Reactome: R-HSA-8865999;Reactome: R-HSA-8875360;Reactome: R-HSA-74749;Reactome: R-HSA-9026519;Reactome: R-HSA-1839117;Reactome: R-HSA-2730905;Reactome: R-HSA-5654720;Reactome: R-HSA-5673001;Reactome: R-HSA-112412;Reactome: R-HSA-9028731;Reactome: R-HSA-5654710;Reactome: R-HSA-1433559;Reactome: R-HSA-912526;Reactome: R-HSA-8875656;Reactome: R-HSA-1236382;Reactome: R-HSA-8853338;Reactome: R-HSA-1963640;Reactome: R-HSA-180336;Reactome: R-HSA-983695;Reactome: R-HSA-8856825;Reactome: R-HSA-5654689;Reactome: R-HSA-9607240;Reactome: R-HSA-1250347;Reactome: R-HSA-5654727;Reactome: R-HSA-512988;Reactome: R-HSA-9027284;Reactome: R-HSA-8856828;Reactome: R-HSA-5655291;Reactome: R-HSA-6807004;Reactome: R-HSA-1963642;Reactome: R-HSA-2871796;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-167044;Reactome: R-HSA-8983432;Reactome: R-HSA-354194;Reactome: R-HSA-74751;Reactome: R-HSA-109704;Reactome: R-HSA-179812;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-5654719;Reactome: R-HSA-9034864;Reactome: R-HSA-5654693;Reactome: R-HSA-1295596;Reactome: R-HSA-9028335;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-5654688;Reactome: R-HSA-180292;Reactome: R-HSA-388841;Reactome: R-HSA-2871809;Reactome: R-HSA-1250196;Reactome: R-HSA-9645135;Reactome: R-HSA-5654699;Reactome: R-HSA-8851907;Reactome: R-HSA-5637810;Reactome: R-HSA-6811558;Reactome: R-HSA-375165;Reactome: R-HSA-5654712 "CD28 dependent Vav1 pathway";"FRS-mediated FGFR3 signaling";"SHC-related events triggered by IGF1R";"MET activates RAS signaling";"PI-3K cascade:FGFR2";"DAP12 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR2 signaling";"Regulation of actin dynamics for phagocytic cup formation";"EGFR Transactivation by Gastrin";"EGFR downregulation";"SHC-mediated cascade:FGFR3";"Tie2 Signaling";"Negative regulation of FGFR3 signaling";"Signaling by FGFR1 in disease";"Signal regulatory protein family interactions";"MET activates RAP1 and RAC1";"Negative regulation of FGFR4 signaling";"Signaling by FGFR3 fusions in cancer";"Signaling by FGFR2 in disease";"RHO GTPases Activate WASPs and WAVEs";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET activates PTPN11";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signal attenuation";"Activated NTRK2 signals through RAS";"Signaling by cytosolic FGFR1 fusion mutants";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI-3K cascade:FGFR4";"RAF/MAP kinase cascade";"SOS-mediated signalling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR3";"Regulation of KIT signaling";"Interleukin receptor SHC signaling";"MET receptor recycling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by FGFR3 point mutants in cancer";"GRB2 events in ERBB2 signaling";"SHC1 events in EGFR signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR1";"FLT3 Signaling";"SHC1 events in ERBB4 signaling";"Negative regulation of FGFR2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Erythropoietin activates RAS";"Clathrin-mediated endocytosis";"Signaling by FGFR4 in disease";"Negative regulation of MET activity";"PI3K events in ERBB2 signaling";"FCERI mediated MAPK activation";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"Signalling to RAS";"Interleukin-15 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Insulin receptor signalling cascade";"PI3K Cascade";"GRB2 events in EGFR signaling";"Downstream signal transduction";"Regulation of signaling by CBL";"SHC-mediated cascade:FGFR4";"Activated NTRK3 signals through RAS";"FRS-mediated FGFR1 signaling";"Spry regulation of FGF signaling";"Activated NTRK2 signals through PI3K";"RET signaling";"Signaling by SCF-KIT";"SHC-mediated cascade:FGFR1";"GAB1 signalosome";"Costimulation by the CD28 family";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB2 signaling";"STAT5 Activation";"SHC-mediated cascade:FGFR2";"MET activates PI3K/AKT signaling";"Constitutive Signaling by EGFRvIII";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"NCAM signaling for neurite out-growth";"FRS-mediated FGFR4 signaling" XP_028901442.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_011189476.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_028900788.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins" XP_011192636.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011176976.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028898979.1 14 KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417 "Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" XP_011189869.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011184321.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011189620.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_011189942.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_011180305.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_011185079.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011179557.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011187267.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_011179844.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011184096.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_028898161.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_028899135.1 23 Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-392451 "G alpha (s) signalling events";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G-protein activation";"G beta:gamma signalling through PI3Kgamma" XP_011178741.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-174154 "Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin" XP_028896909.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_028895323.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011181280.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_011193705.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011192703.1 6 MetaCyc: PWY-6309;MetaCyc: PWY-7765;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651 "L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_028902067.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_011194282.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011185074.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011182878.1 29 MetaCyc: PWY-5078;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00010+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-3162;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-6587;MetaCyc: PWY-5082;MetaCyc: PWY-6333;KEGG: 00592+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-7111;MetaCyc: PWY-5076;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-6871;MetaCyc: PWY-5079;MetaCyc: PWY-6342 "L-isoleucine degradation II";"Fatty acid degradation";"Chitin degradation to ethanol";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Glycolysis / Gluconeogenesis";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol II";"L-tryptophan degradation V (side chain pathway)";"Salidroside biosynthesis";"Tyrosine metabolism";"L-valine degradation II";"Pyruvate fermentation to ethanol III";"L-methionine degradation III";"Acetaldehyde biosynthesis I";"alpha-Linolenic acid metabolism";"Glycine, serine and threonine metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"L-leucine degradation III";"Metabolism of xenobiotics by cytochrome P450";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"Phenylethanol biosynthesis";"Chloroalkane and chloroalkene degradation";"Serotonin degradation";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Noradrenaline and adrenaline degradation" XP_011196093.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_028899998.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_028900793.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_011176971.1 3 MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_011191080.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_011189873.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" XP_028898958.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation" XP_011193504.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex" XP_011182962.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_028899402.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011196052.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I" XP_011189073.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_028897944.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028899967.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_011182283.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011176475.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-196299 "EML4 and NUDC in mitotic spindle formation";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" XP_028893646.1 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747 "Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated" XP_028902168.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028899981.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011186865.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_028899788.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_011176487.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_028896910.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_011194371.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011191692.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_011186858.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028898342.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011186900.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-174411 "Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere" XP_011190740.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_011190735.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_011176806.1 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416 "Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_011181946.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011179081.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_028900999.1 26 Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158 "Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor" XP_011192914.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_011179731.1 13 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series" XP_028894425.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_028895912.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_011179345.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011192869.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205 "Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes" XP_011184812.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894600.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging" XP_028898827.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011187001.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_011196782.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_011195637.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_011183897.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011185606.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription" XP_011177685.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_028896422.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_011188619.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011190582.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_011188934.1 14 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-1632852;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"Macroautophagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy" XP_028898757.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_011180860.1 9 KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590 "Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione conjugation" XP_011190153.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241 "Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Peroxisomal protein import" XP_011194076.1 10 Reactome: R-HSA-437239;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Recycling pathway of L1";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_011191707.2 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_011185001.1 8 KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27 "Propanoate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate metabolism" XP_011189993.1 23 Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-4086398 "ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Ca2+ pathway" XP_011187816.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_011176541.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028900835.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_028898341.1 6 Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-73930;Reactome: R-HSA-110362 "PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair" XP_011180561.1 4 KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475 "Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_011191277.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895819.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_011185197.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011178659.1 8 Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Photosynthesis";"Insulin receptor recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_028900477.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237 "Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2" XP_011193808.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011186646.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011192247.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011195164.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_011187834.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_028896228.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_011180744.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028899997.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_011196010.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_028896091.1 3 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_011177722.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_028894208.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028894209.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028897380.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011190507.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_028900783.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_028899390.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_028895473.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_028895927.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_028899781.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_011196639.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011179472.2 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_011184887.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_011183305.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090 "Collagen degradation";"Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures" XP_011182579.1 12 Reactome: R-HSA-1251985;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-193692;Reactome: R-HSA-75893;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232 "Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Regulated proteolysis of p75NTR";"TNF signaling";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_011182504.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028898522.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_011192536.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_011177572.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_028895627.1 5 Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5205685;Reactome: R-HSA-977225 "Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation" XP_028894007.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_011193001.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_028901591.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_011192201.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028899771.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_011196381.1 6 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 00562+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)" XP_028900648.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011185974.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_011193749.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_011185198.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011190050.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1" XP_011195165.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_011193574.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_028896577.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011196710.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354 "Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy" XP_011181617.1 11 MetaCyc: PWY-5154;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;KEGG: 00250+6.3.5.5 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism" XP_011191560.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_011192366.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028896326.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_028895608.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_011179791.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894156.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180878.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_011195150.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_028898159.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_028899995.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_028900454.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_028895855.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation" XP_028893699.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" YP_004891171.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011194152.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_028901961.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_011194864.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011194502.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_028898690.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_028898867.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_011191612.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011192091.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011192288.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_011195591.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_011177063.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_028900500.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_028896365.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_028895643.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_028893889.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894201.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011185879.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_011194388.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_011182967.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_011178105.1 4 KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis" XP_028899905.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_011187562.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011179249.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-5632684 "Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state" XP_011193224.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_011194380.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_011196650.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_011186150.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011193210.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_011178443.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028898541.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011181741.1 13 MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2160916 "Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation" XP_011182686.1 18 KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7115;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;MetaCyc: PWY-5913 "Phenylalanine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)" XP_011194982.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-2565942;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_028901946.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_011182290.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028899977.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_011184005.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_011189085.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_011196659.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028899782.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_011188350.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_028896115.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_011176434.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC" XP_011182085.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_011189611.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_011183943.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011187333.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011195414.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_011191846.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028897639.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011190811.1 34 Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-9639288;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-6784531 "SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amino acids regulate mTORC1";"snRNP Assembly";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"HCMV Early Events";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus" XP_011182937.1 10 KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11 "Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_011177419.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011182870.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843 "Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation" XP_011176660.1 25 Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-437239 "COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1" XP_011182746.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_011176562.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_028896463.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011177434.1 29 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-5696400 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER" XP_011188833.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028895573.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_011178458.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" XP_028899578.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_011177225.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_028897070.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028899703.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011190730.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011193337.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011180819.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_011180166.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_011192456.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894413.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011176653.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028893830.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011193487.1 5 Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695 "Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation" XP_028897772.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_011184898.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68884 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis" XP_028899982.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_028893702.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_011181598.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_011183725.1 7 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism" XP_011190027.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_011192917.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_011195760.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011191924.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_011181786.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028896460.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011190895.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011178853.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_011196235.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_011188858.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_028893577.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011177935.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011181703.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_028897467.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028895596.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_011196705.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_011191434.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011195045.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_011196510.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_028899893.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_028897505.1 26 Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907 "Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_011178448.1 11 Reactome: R-HSA-8964539;Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6964;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2 "Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism" XP_011193479.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_028894621.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_011179408.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_028899900.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_011187886.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_011176622.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011188143.1 5 MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_011182047.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_011182881.1 29 KEGG: 00260+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-7111;MetaCyc: PWY-5751;MetaCyc: PWY-6313;KEGG: 00625+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-6871;MetaCyc: PWY-5079;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-5486;KEGG: 00982+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5082;MetaCyc: PWY-6333;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-6587 "Glycine, serine and threonine metabolism";"Butanol and isobutanol biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Phenylethanol biosynthesis";"Serotonin degradation";"Chloroalkane and chloroalkene degradation";"Metabolism of xenobiotics by cytochrome P450";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"Noradrenaline and adrenaline degradation";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Chitin degradation to ethanol";"Retinol metabolism";"Fatty acid degradation";"Pyruvate fermentation to ethanol I";"Glycolysis / Gluconeogenesis";"L-isoleucine degradation II";"Pyruvate fermentation to ethanol II";"Drug metabolism - cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"L-methionine degradation III";"Acetaldehyde biosynthesis I";"Salidroside biosynthesis";"Tyrosine metabolism";"L-valine degradation II";"Pyruvate fermentation to ethanol III" XP_028897703.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_011194992.1 7 MetaCyc: PWY-7836;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839 "Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis" XP_011187890.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_028896960.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_011194566.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_028893953.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_028896662.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_028902102.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-381676 "Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_011187725.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357 "VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling" XP_011195501.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_028901200.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_011190866.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_011196297.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011182282.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011187811.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_028893664.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028893719.1 9 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_011191464.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660 "G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway" XP_028897374.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011178198.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_011177995.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011179134.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028893658.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011195668.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" XP_028898768.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_011182738.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011185944.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_011182284.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011193581.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028896667.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_028898682.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011195965.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011182665.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_011195075.1 5 MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154 "Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase" XP_028899602.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011192731.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_011196787.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011196731.1 14 Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-7254;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Respiratory electron transport" XP_028900224.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_011178220.1 4 Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292 "Hyaluronan uptake and degradation";"HS-GAG degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome" XP_011186576.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011189505.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_028900801.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001 "Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade" XP_028900840.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011193614.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_028896961.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_028902227.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_011179706.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028896428.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028900223.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_028893642.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257 "S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion" XP_028894030.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011187832.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_011179469.1 16 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-674695;Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167287 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Pre-transcription Events";"Neddylation";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery" XP_011179949.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011181240.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_028895706.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_011178938.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011180601.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_028901061.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_028901413.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011188437.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011192000.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_011196074.2 5 Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164 "MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade" XP_011178415.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_028901068.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_011179306.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_011192585.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_011187440.1 13 Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474244 "Signaling by PDGF";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"NCAM1 interactions";"Collagen degradation";"Laminin interactions";"Integrin cell surface interactions";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Extracellular matrix organization" XP_011178433.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011178984.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011188138.1 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I" XP_028897673.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_011184599.1 8 Reactome: R-HSA-6791462;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;Reactome: R-HSA-8950505;Reactome: R-HSA-71336;Reactome: R-HSA-163754;MetaCyc: PWY-1861 "TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_011191413.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_011192983.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_011179302.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_028896535.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011192595.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_028894257.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011192936.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_011196461.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_011195811.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028900252.1 13 KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52 "Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series" XP_011180740.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_028898213.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_028900611.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011179917.1 14 MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;KEGG: 00670+2.1.2.1;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-181 "Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Photorespiration " XP_011189764.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028899962.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_011193236.1 11 Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation" XP_011179904.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011194066.1 5 MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39 "Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Arginine and proline metabolism" XP_011196415.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_028893937.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_028897751.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_011194513.1 3 KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis" XP_011190459.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011178441.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028894567.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011190519.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_011185930.1 24 Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483 "Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Cilium Assembly";"Gap junction assembly";"RHO GTPases Activate Formins";"HCMV Early Events";"Activation of AMPK downstream of NMDARs" XP_028901440.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_028894895.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011196053.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I" XP_028896772.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_028899455.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011191025.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_028900572.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_028894862.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_028896069.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_028896668.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011185727.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_011176473.1 22 Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-432142 "CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL" XP_028894517.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_028899541.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011194617.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011185472.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_011181731.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_011193926.1 5 Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383 "Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_011193709.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_011189838.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214 "Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins" XP_011196416.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_011191943.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011196101.1 3 Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90 "Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_011193672.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_011176936.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011190943.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_028897856.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_028897801.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_011189140.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011192827.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028897063.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028894349.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204 "Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_011181590.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_028898608.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_028896923.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_011188315.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_011192932.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_028896731.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028902128.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011185276.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_011192026.1 7 Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606 "PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011191289.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_028894775.1 10 Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_011192432.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_011192750.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_028897312.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_028895251.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011180670.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_011178269.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_011186814.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_028893555.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011194273.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_028897735.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011184129.1 13 KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-2206308;Reactome: R-HSA-4085001 "Sphingolipid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"MPS IV - Morquio syndrome B";"Sialic acid metabolism" XP_028896340.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011176470.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025 "Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"EML4 and NUDC in mitotic spindle formation" XP_011192240.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_011196741.1 57 Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751 "FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Degradation of AXIN";"Neutrophil degranulation";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity" XP_011191538.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011181128.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011190476.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_028899973.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_011176989.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_011188338.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011186046.1 8 Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2 "Amino acids regulate mTORC1";"Oxidative phosphorylation";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Photosynthesis" XP_011177698.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011184273.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028894072.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_011181707.1 10 Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122 "Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_011196213.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_011181464.1 16 Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-5603041;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702;Reactome: R-HSA-975110;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-975138;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-6811558;Reactome: R-HSA-166058;Reactome: R-HSA-5603037 "MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"IRAK4 deficiency (TLR5)" XP_011188172.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_011177730.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_011187618.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_011177959.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_028895308.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_028895449.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011196009.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_028901173.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_011184344.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_011189018.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852 "Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy" XP_011179813.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028897528.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_011194773.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_011180637.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011196468.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_011180111.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011184513.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_028897587.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011177299.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_011188254.1 11 Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862 "Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_011193229.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_011182755.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_011196367.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011189598.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_011186886.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_028894763.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028900603.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_028893588.1 14 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.42;Reactome: R-HSA-75896;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;Reactome: R-HSA-9033241 "Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Peroxisomal protein import" XP_011177640.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011184460.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028896356.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011179606.1 7 Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695 "RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Neutrophil degranulation" XP_028897991.1 6 KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234 "Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III" XP_011183751.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_011190174.1 10 KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922 "Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_011192250.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011196706.1 13 KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-6545 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_028899885.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011183908.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_011191545.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011196408.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_011191775.1 8 MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179 "Adenine and adenosine salvage V";"Purine salvage";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine deoxyribonucleosides degradation I" XP_028899353.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_011183178.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011191072.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011192705.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_011178758.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_011189238.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011177431.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_028894084.1 6 KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism" XP_011177167.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events" XP_011194251.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_028897645.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_011178716.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_011179880.2 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_011184089.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684 "Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state" XP_028896678.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028896720.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_011182494.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_028897319.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_011187254.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011196956.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011195438.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_028894249.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_028893665.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895278.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_028893575.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028899354.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011189447.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011180438.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_011180539.1 17 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_011190990.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_011188155.1 4 KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Glycerol degradation I" XP_011194851.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946 "Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin" XP_028898134.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011190186.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011192749.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_011184665.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011183077.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695 "Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation" XP_011179013.1 3 KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" XP_011188054.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_011180625.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011190521.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_011190791.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_011189204.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_011191244.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011184079.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_011187681.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011178754.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028899915.1 2 Reactome: R-HSA-8981607;Reactome: R-HSA-203615 "Intracellular oxygen transport";"eNOS activation" XP_011190192.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028896439.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" YP_004891165.1 7 MetaCyc: PWY-3781;MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;Reactome: R-HSA-611105 "Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis";"Fe(II) oxidation";"Respiratory electron transport" XP_011193923.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011177729.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_011195914.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_011186339.1 5 KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668 "Glycerophospholipid metabolism";"Synthesis of PG";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I" XP_011180460.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028894521.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_011190844.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_011186425.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011177648.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination" XP_011186254.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_011177297.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_028896570.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_011197132.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011195461.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028900306.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_011193235.1 11 Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6796648 "RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_028900614.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011197055.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.42;Reactome: R-HSA-75896;MetaCyc: PWY-8055;MetaCyc: PWY-7411 "Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Peroxisomal protein import";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)" XP_011196925.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_028893682.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_011192200.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_028900000.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy" XP_011195080.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_011179610.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028894679.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_011183780.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_028896194.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028897506.1 26 Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629 "Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation" XP_028902188.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6362 "Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_011177378.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_028900807.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324 "Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"HSF1-dependent transactivation";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_028896450.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011179882.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011186024.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011195830.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state" XP_011189568.1 6 Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8957275 "RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation" XP_011194873.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_011179919.1 14 MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622 "Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"One carbon pool by folate";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Cyanoamino acid metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)" XP_011190376.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage" XP_028899776.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_028895572.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_028898010.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_011191152.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_011182555.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_011184225.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_028898975.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_011197125.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011193516.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011178742.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_011191278.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011186056.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_011192886.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_028900011.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_011177724.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_011186891.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_011190726.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_011193291.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_028899520.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_028901291.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011191223.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-5620922 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium" XP_011178815.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011183939.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011178713.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_011193355.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_011189790.1 3 Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_028899803.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_028894473.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_028895489.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_028901147.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011186343.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_028898543.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" XP_028894898.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_028897959.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011195886.1 6 KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433 "Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_011191857.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_011189536.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011184309.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011188521.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_011191578.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028895088.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011194829.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_028900474.1 29 Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_011190839.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695 "Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex" XP_011180063.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011183772.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_028893756.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174084 "Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_011190775.2 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011179574.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011188398.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_028899543.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028895693.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011194946.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766 "Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown" XP_028901018.1 6 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" XP_011182373.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028895962.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011193562.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011189026.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180635.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011178590.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011179950.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_011195712.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_028899274.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_011187782.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_028896699.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011187453.1 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" XP_011179103.1 12 MetaCyc: PWY-6936;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-1187;MetaCyc: PWY-7901;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601 "Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan" XP_011179037.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011185445.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_028899110.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_011192010.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011193661.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011176915.1 19 Reactome: R-HSA-8964616;Reactome: R-HSA-418885;Reactome: R-HSA-114604;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-428543;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-3928662;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-5627123;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220 "G beta:gamma signalling through CDC42";"DCC mediated attractive signaling";"GPVI-mediated activation cascade";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"Inactivation of CDC42 and RAC1";"Myogenesis";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"EPHB-mediated forward signaling";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"RHO GTPases activate PAKs";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins" XP_028893570.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011184904.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_028898264.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186748.1 13 Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-167590 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef Mediated CD4 Down-regulation" XP_028896126.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_011183330.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_011178956.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028894923.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011187752.1 7 MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25 "Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_028893547.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_011183519.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_011177868.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_011194234.1 7 Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid" XP_028900524.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011184764.1 4 MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906 "N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_011182229.1 2 Reactome: R-HSA-1461973;Reactome: R-HSA-1462054 "Defensins";"Alpha-defensins" XP_028896199.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion" XP_011178845.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_011179229.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028895846.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_028902118.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_011191248.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_028898053.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011180046.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011185616.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011177755.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Dual Incision in GG-NER" XP_028898846.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028899968.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_011192913.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028897176.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_028898767.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_028900329.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011194456.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011189314.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011177403.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_028896067.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_028895098.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_028900848.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_028899958.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_011194810.2 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_011177432.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_028898540.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011186149.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011177618.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_011190953.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_011194788.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_028899889.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011186753.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_011194505.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_028893789.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_028895107.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011192303.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_011189312.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_011189788.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_011195444.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028897407.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_028900849.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011194510.1 9 MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-5981 "1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III" XP_011187506.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_011182329.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028898076.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_011177052.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5218921 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"Downstream signal transduction";"VEGFR2 mediated cell proliferation" XP_011194976.2 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_011182709.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_011177763.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_011189118.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028898142.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_028900456.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_011191462.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011191200.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_011182710.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011188722.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_011185466.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_028900176.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011177322.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_028899979.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_028896776.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_028900034.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011194860.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011176481.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-196299 "EML4 and NUDC in mitotic spindle formation";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" XP_011181739.1 13 KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101 "Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation" XP_028894162.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011194045.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011178128.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_011181692.1 42 MetaCyc: PWY-5136;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7779;MetaCyc: PWY-7216;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00623+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-6583;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-5789;MetaCyc: PWY-6946;MetaCyc: PWY-7654;MetaCyc: PWY-7401;MetaCyc: PWY-7726;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.35 "Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Spodoptera littoralis pheromone biosynthesis";"Methyl tert-butyl ether degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Androstenedione degradation";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Toluene degradation";"Phenylalanine metabolism";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Fatty acid degradation";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Geraniol degradation";"2-methylpropene degradation";"Tryptophan metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Fatty acid salvage";"Limonene and pinene degradation";"Caprolactam degradation";"Fermentation to 2-methylbutanoate";"Glutaryl-coa degradation";"Fatty acid elongation" XP_028900283.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011190553.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028896481.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_011191589.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181803.1 5 Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_011185852.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_011186594.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_028894900.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_028894620.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_028894390.1 10 MetaCyc: PWY-7003;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1 "Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms" XP_011190526.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_028900416.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_011176676.1 11 MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism" XP_028899741.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_028901019.1 6 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" XP_011192014.1 7 Reactome: R-HSA-446193;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6470;MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-5633231;MetaCyc: PWY-6385 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)" XP_011182367.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011181052.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028900607.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011193189.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_011196670.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011187822.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028896666.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011187299.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_011186335.1 5 Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621 "Pyrimidine salvage";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine catabolism" XP_028899802.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_011182205.1 6 KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020 "Photosynthesis";"Cristae formation";"ATP biosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import" XP_011190168.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187 "Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress" XP_011180839.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011182527.1 5 Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530 "PI3K Cascade";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_028894409.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011187383.1 18 KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5913;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1 "Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis" XP_028894280.1 8 MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_011190125.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011194199.1 7 KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11 "Fructose and mannose metabolism";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis" XP_011190709.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_011189824.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011178913.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_011178398.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_011176939.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_028899699.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011186227.1 5 Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_011184003.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_011195086.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011195407.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011195059.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_011191125.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_028897704.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011176464.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_011186546.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011191204.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122 "G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_011178834.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_028897240.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011176524.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011178573.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_011188284.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829 "Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy" XP_011180613.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_011191066.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_011178397.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_011194739.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011195469.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011185637.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_028894167.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_011188626.1 6 MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168 "Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)" XP_011180770.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_028894288.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_011190309.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_028897496.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011185022.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_011196868.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_028899780.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_011184710.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_011181576.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_028901733.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011179416.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_011184693.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_028897040.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_011197144.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_028895864.1 5 KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3 "Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism" XP_011177741.1 5 MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5381 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)" XP_011191497.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011184443.1 5 Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225 "Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_011185913.1 10 Reactome: R-HSA-1660499;MetaCyc: PWY-6352;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Inositol phosphate metabolism";"mTOR signaling pathway";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection" XP_011180485.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_011194961.1 4 KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_011191132.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_011181185.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_028899757.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_028893876.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693565;MetaCyc: PWY-7511 "Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination" XP_011179431.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_028899969.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011190936.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_028901677.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028894762.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011184858.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011188265.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_011178807.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_011192495.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_028897076.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895630.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_028895455.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_011186683.1 6 KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-3341 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)" XP_011195600.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011194181.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_011181512.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" XP_011190995.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_011192457.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_011195825.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011195919.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011188049.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_011188792.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_011183823.1 5 KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" XP_028893653.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-2467813 "Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids" XP_011195621.1 1 Reactome: R-HSA-1632852 "Macroautophagy" YP_004891172.1 7 KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-6692;Reactome: R-HSA-611105;MetaCyc: PWY-5083;Reactome: R-HSA-6799198 "Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Fe(II) oxidation";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis" XP_028898048.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028897266.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_028894076.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_028893576.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011191046.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_011194362.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_011190224.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690 "SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"HCMV Early Events" XP_011179402.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_028894792.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028894177.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_011186255.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_028899894.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_028900455.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_011178201.1 8 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6" XP_011196217.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_011191595.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX" XP_011186415.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011185469.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_028896725.1 13 KEGG: 00600+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;Reactome: R-HSA-4085001 "Sphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Sialic acid metabolism" XP_011195817.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_028894890.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011182957.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3" XP_028893556.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_028894819.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700 "Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_028899114.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011179980.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028898799.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781 "Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis" XP_011183859.1 8 Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-6798695 "Surfactant metabolism";"Purine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Neutrophil degranulation" XP_028900405.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011183300.1 24 Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-500657 "G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Presynaptic function of Kainate receptors" XP_011193008.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_011189206.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011192504.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_011194988.1 7 MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7838 "Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis" XP_011191705.2 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_011185075.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028899647.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_028901143.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011182357.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_011184624.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011187089.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_011177619.1 4 MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_011180515.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300 "Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_028895281.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011186419.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_011190994.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_011186971.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_028899271.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_028896429.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011191559.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_011187265.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011196430.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_011178406.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_028897276.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028895362.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011186925.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_011176656.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011181723.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_028894910.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011180059.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_028898027.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_011185128.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011186710.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028896370.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011191575.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011194889.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011186011.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011178561.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_028895335.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1 "Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Purine metabolism" XP_011194895.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_011177488.1 11 KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_011191990.1 2 Reactome: R-HSA-203615;Reactome: R-HSA-8981607 "eNOS activation";"Intracellular oxygen transport" XP_028894223.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028899956.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_011192451.1 17 Reactome: R-HSA-9022692;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;KEGG: 05170+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-174178;Reactome: R-HSA-5663220;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025 "Regulation of MECP2 expression and activity";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Human immunodeficiency virus 1 infection";"Mitotic Prometaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RHO GTPases Activate Formins";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation" XP_028895468.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028900790.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_028896304.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_011176474.1 22 Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340 "Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex" XP_011188892.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028900843.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011177754.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_011177760.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_011182868.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619 "2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN" XP_028898683.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011181187.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_028895648.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011196647.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_028896294.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_011190164.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_011179400.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011185962.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011190959.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_011184678.1 18 MetaCyc: PWY-6608;MetaCyc: PWY-6644;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;KEGG: 00983+2.4.2.3;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5695;Reactome: R-HSA-73621;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-73614 "Guanosine nucleotides degradation III";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Purine metabolism";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Drug metabolism - other enzymes";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Pyrimidine catabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage" XP_028897458.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028897694.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_028894243.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011191175.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_028901779.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_028899319.1 4 Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_011185697.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011195043.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_028900451.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_028902233.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_028894785.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_011197012.1 6 KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780 "Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism" XP_011192742.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_011194916.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_011179730.1 13 Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_011194857.1 18 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-72689 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits" XP_011185455.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_011196210.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011184732.1 8 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_028898458.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011189240.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011193271.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_028894071.1 3 Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis" XP_011180169.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028899508.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_011181136.1 5 Reactome: R-HSA-205043;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-209560 "NRIF signals cell death from the nucleus";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival" XP_011180528.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011194129.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011189446.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011188830.1 14 MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5 "Anandamide biosynthesis I";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_011186029.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_011186021.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320 "Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation" XP_011181588.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_011193226.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_011177121.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_028899641.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011196906.1 1 Reactome: R-HSA-419771 "Opsins" XP_011195062.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011192088.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_011184215.1 5 Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_028894410.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011184152.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4 "Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_011183592.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011186592.1 4 MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051 "Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_011186884.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011193948.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_028899118.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_011182376.1 9 MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533 "4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis" XP_011182006.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_011188146.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_028897114.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_011178360.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206302;Reactome: R-HSA-2024101 "HS-GAG degradation";"MPS I - Hurler syndrome";"CS/DS degradation" XP_011178095.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_011191436.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_011185053.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011194246.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011192331.1 7 Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921 "Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation" XP_028896196.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926 "G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_011192532.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_028900744.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_028896957.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_028898018.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011179038.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_011197011.1 13 Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802955 "Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_028896358.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011180239.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_011188152.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011194200.1 7 KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263 "Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism";"Gluconeogenesis" XP_011192145.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011188924.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028896259.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_011197091.2 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" XP_011192904.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_028900494.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011194108.1 26 Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568 "FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase" XP_011193347.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011180464.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_028896920.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_011189064.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_011197069.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011188932.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_028894506.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_028894133.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation" XP_011190810.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011188198.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_011187540.1 52 Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-749476;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-5250924;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-113418 "TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"B-WICH complex positively regulates rRNA expression";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex" XP_011187311.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_011190001.2 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_011188804.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_028894401.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_011196723.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180668.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_011187339.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_011184216.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_028896404.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028900475.1 11 Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-975634 "Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport" XP_028900342.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_028897391.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011177193.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" XP_011183560.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011183824.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084 "Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_011176499.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028896532.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011184121.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011179371.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011195119.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011189992.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389957 "BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_028897949.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011187263.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011190016.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_011195222.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_011190980.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_011194782.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_028900005.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy" XP_011192716.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination" XP_011177295.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_011193622.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_011183903.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011187329.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_028896416.1 3 Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_011182372.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028895664.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_028894258.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011193944.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_011187821.1 17 Reactome: R-HSA-6783310;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607 "Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Thermogenesis";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Meiotic synapsis";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Processing of DNA double-strand break ends" XP_028893942.1 1 Reactome: R-HSA-376172 "DSCAM interactions" XP_011195328.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_011180499.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011191579.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028900035.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011189227.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559 "Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway" XP_011177427.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_011176903.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_011179901.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_028897713.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_028899851.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028896677.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011192649.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_011185085.1 16 Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168 "APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011181261.1 17 MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle" XP_028894031.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028900064.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011185614.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_028901044.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_011190700.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_011188551.2 3 Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_011184772.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_028902180.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028899132.1 8 Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111463 "Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs" XP_011194795.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_011190141.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_028902157.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028900649.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011195459.1 6 MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II" XP_011191922.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_011186687.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_011181755.1 13 Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117 "EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"RHO GTPases Activate ROCKs" XP_011195013.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_028895477.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011190838.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-180910 "Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs" XP_011187647.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011184335.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_011183582.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011177233.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011179683.1 14 Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_028899313.1 7 MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183 "Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_028902163.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_028896921.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_028900153.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011186599.1 4 KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202 "Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism";"Metabolism of polyamines" XP_011182214.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_028899546.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011185118.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_011187178.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_028894524.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011195032.1 33 Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377 "SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Transcriptional regulation by small RNAs";"HCMV Early Events";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"snRNP Assembly";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins" XP_028898708.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011185448.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_011187676.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_028897778.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_011178271.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_011192023.2 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_011194928.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_028896287.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_011196973.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_028899521.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_011185916.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028894735.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011182702.2 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_011190434.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" XP_028900299.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_011182273.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_028895756.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_028898927.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028899346.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_011189848.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;MetaCyc: PWY-6983 "Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis" XP_028895692.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028900549.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_011179224.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011176877.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011190710.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_011189798.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_011191298.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011179555.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916 "MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation" XP_028898812.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_011188114.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_028894740.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011186637.1 6 MetaCyc: PWY-6731;MetaCyc: PWY-5941;MetaCyc: PWY-6737;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238 "Starch degradation III";"Glycogen degradation II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II" XP_011186655.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_028893491.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_028900748.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_028896103.1 12 Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-193692;Reactome: R-HSA-2122948 "Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"Collagen degradation";"TNF signaling";"Signaling by EGFR";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_011183609.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011192209.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011180487.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_011179330.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783 "Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome" XP_028897359.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_011184651.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_011184318.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011188274.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_011177252.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011191428.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011196290.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_028894826.1 12 Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-2821;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-801 "Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion" XP_028902101.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production" XP_028898195.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472 "SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011180434.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011189057.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_011178099.1 12 MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6978;MetaCyc: PWY-5857 "Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_028896664.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011196791.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011187762.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_011196396.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_011180174.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011184447.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028900679.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_011188064.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_028894197.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011184058.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011187510.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_011192304.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_011192346.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_028901943.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594 "G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events" XP_011179083.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011195012.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_028895628.1 5 Reactome: R-HSA-5689877;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-983168 "Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011186564.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011186196.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_028894113.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186085.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_011194271.1 3 Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078 "GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" XP_011191421.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011182020.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis" XP_028899031.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_028895757.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_011189752.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_011181488.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_011196634.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028894204.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028898335.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011182368.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379 "Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres" XP_011189603.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_011185902.1 7 Reactome: R-HSA-2151201;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613 "Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Cristae formation" XP_011187864.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011185834.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186069.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962 "Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex" XP_011180334.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011179380.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_028898741.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_011182153.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_028899993.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_028894702.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593 "MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity" XP_011191118.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-9603505;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6796648 "RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_011193336.1 29 Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-69541;Reactome: R-HSA-69473;Reactome: R-HSA-6803204;Reactome: R-HSA-5693565;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-3371453;Reactome: R-HSA-6803207;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-349425;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Stabilization of p53";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Methylation";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_011177999.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011189839.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885 "ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins" XP_011180799.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_011186560.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_011195687.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011182815.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011180013.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028901405.1 8 MetaCyc: PWY-7979;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_011182774.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_011191546.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011177492.1 11 Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302 "VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation" XP_011180137.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011184151.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_028896197.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926 "G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_011182559.1 6 KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484 "Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)" XP_028899724.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_011181858.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_011197124.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011179344.2 13 MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5913 "Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)" XP_028895600.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_028898421.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_011189670.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_011195610.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_028894599.1 5 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_011185838.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028895527.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011178538.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_028894195.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011194232.1 7 Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12 "Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)" XP_028894678.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_028901802.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011181977.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR" XP_011188534.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_011178053.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028898286.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_028900832.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_011192330.1 7 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism" XP_028902132.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011186570.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_011196169.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_011190066.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107 "HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_011195245.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011189168.1 7 Reactome: R-HSA-9018896;Reactome: R-HSA-2142691;Reactome: R-HSA-9023661;Reactome: R-HSA-9018681;Reactome: R-HSA-9018676;Reactome: R-HSA-9020265;Reactome: R-HSA-6798695 "Biosynthesis of E-series 18(S)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of protectins";"Biosynthesis of D-series resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Neutrophil degranulation" XP_011191984.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028898832.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011178478.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011181415.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6796648 "RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_028901971.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_011195492.2 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_011189504.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_011192271.2 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_011188815.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_011182274.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011193470.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028895789.1 6 MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_028900448.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011182728.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_028900378.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011179142.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011180266.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011192889.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028895222.1 3 Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457 "Ca2+ pathway";"Rap1 signalling";"cGMP effects" XP_011185002.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_028893933.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_028897948.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011178794.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_028894402.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_011187900.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028899113.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_028893447.1 13 MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-6383 "Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" XP_011181648.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-174154 "Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin" XP_011191852.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_011181734.1 15 Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519 "Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression" XP_011179484.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011188006.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_011176988.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_011177847.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6722 "3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis" XP_011179237.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_028901452.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_028897631.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028901921.1 11 Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660 "Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway" XP_011182319.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176407 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_011176961.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011187381.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011189534.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949 "2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA" XP_011192009.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011189548.1 10 Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111459 "Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage" XP_011187564.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_011194582.1 7 Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;Reactome: R-HSA-2151201 "Cristae formation";"Photosynthesis";"ATP biosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis" XP_011179198.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_028896683.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011187585.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_028894180.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011180012.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011182737.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_011179105.1 12 MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-6842 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II" XP_011179108.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_011190169.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_028899651.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_028901292.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011189079.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_028893554.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011184905.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_028894893.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_011189340.1 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" XP_028900518.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011188526.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_011188522.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011181343.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028899510.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_011184182.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_011185196.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028896288.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011190047.1 17 Reactome: R-HSA-1433557;Reactome: R-HSA-69601;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-75035 "Signaling by SCF-KIT";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Thermogenesis";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_028894909.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011179723.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011184902.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_011177839.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_011196701.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011193774.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011182896.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_011192950.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_028894741.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_028896401.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011189342.1 14 Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-450520;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-69273 "Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition" XP_028898845.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011178576.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_028901441.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_028897117.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_028896709.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_011185509.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028894814.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_011186473.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism" XP_028894225.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011185732.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011181725.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011190407.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_011191823.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_011196422.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-113418 "Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex" XP_028896853.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-3000170;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;MetaCyc: PWY-7221;Reactome: R-HSA-212676;KEGG: 00230+2.7.4.8 "Nephrin family interactions";"Syndecan interactions";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Guanosine ribonucleotides de novo biosynthesis";"Dopamine Neurotransmitter Release Cycle";"Purine metabolism" XP_028894946.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_011196494.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_011185204.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_028899495.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_011196275.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011187337.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_011182566.1 6 MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_028900610.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011181657.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_028900606.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011177088.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011178759.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028893571.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011183476.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011192402.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7858 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II" XP_028896872.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_011192969.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" XP_011197148.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028898309.1 18 MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" XP_011193201.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_011189565.1 7 Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080 "Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)" XP_011186561.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_011192631.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011182540.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011194917.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I" XP_028893910.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_011192243.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011190420.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_011189871.1 18 MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Methane metabolism";"Pyruvate metabolism";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)" XP_011192555.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_028893956.1 5 Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_028894217.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011195246.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_011181943.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028895704.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_011190848.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_028900889.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_028897463.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011185859.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_011177832.1 9 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation" XP_011180742.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_028895598.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_028902051.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011194790.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011190933.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011178496.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459 "Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_028899832.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011193524.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_028896351.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011187456.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_028893854.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011197147.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_011192452.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_028901618.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028898109.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_028894525.1 15 Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-9009391 "Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"G alpha (q) signalling events";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Signaling by SCF-KIT";"RET signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling" XP_011186906.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_011195775.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011178359.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011176941.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011194175.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028901781.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_011187889.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011190614.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_011188627.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246 "Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_011177906.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011178088.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_011196386.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_011190570.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011186864.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_011178566.1 3 Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859 "Protein methylation";"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade" XP_011192440.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)" XP_028899551.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122 "G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_011184207.1 9 MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;Reactome: R-HSA-196780 "Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism" XP_011180507.1 7 Reactome: R-HSA-1989781;Reactome: R-HSA-77346;Reactome: R-HSA-77348;MetaCyc: PWY-7094;KEGG: 00071+1.3.8.7;KEGG: 00280+1.3.8.7;Reactome: R-HSA-77288 "PPARA activates gene expression";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid salvage";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids" XP_011193521.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_028898016.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_011178619.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028896569.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_028896128.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011180547.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_011183011.1 7 MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;Reactome: R-HSA-70221;Reactome: R-HSA-6798695 "Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation" XP_011191097.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011185260.1 17 MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_028900570.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011193896.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011179764.1 13 MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5913 "TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)" XP_028899483.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011196711.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011177470.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011194832.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011182497.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011192999.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011188337.1 11 Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942 "Telomere C-strand synthesis initiation";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)" XP_011195561.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011182190.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028898712.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5620924;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Macroautophagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Intraflagellar transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_011191420.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011180011.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011194275.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011187678.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011179333.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_011183091.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028896873.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_011191048.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_011178069.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_028897775.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_028896331.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011197053.1 14 KEGG: 00564+2.3.1.15;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.42;Reactome: R-HSA-75896;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453 "Glycerophospholipid metabolism";"Peroxisomal protein import";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis" XP_011178732.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_028894613.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011185990.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011189433.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011177009.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_028896968.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180793.1 4 Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_011193360.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_028899057.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011178898.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011196648.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_028894916.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_028901808.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011190094.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011178483.1 15 Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-416476;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-2219530 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"RET signaling";"Interleukin receptor SHC signaling";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"G alpha (q) signalling events";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_011178790.1 8 KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1 "Fructose and mannose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_028900079.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_011195725.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_011190195.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028899910.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_028898604.1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_028897049.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028894504.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_028901679.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011183348.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028895533.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_011192576.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_011195386.2 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_011194110.1 26 Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3214847 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"HATs acetylate histones" XP_011184521.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_011187675.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_028901724.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011194034.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_028897586.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_028896291.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_028897696.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_011176477.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558 "RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011193947.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_011187623.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028901508.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011183312.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_011181244.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_028894256.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011177191.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_011191702.2 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_011190166.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_011180261.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_011177094.1 12 Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972 "Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_028899706.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011190262.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011176500.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011177636.1 5 Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex" XP_028897752.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_028894508.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011183125.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_011192689.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_011178939.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028896531.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011191700.2 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_011177188.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011186327.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_011183907.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_011190400.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_028896761.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011196073.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964 "MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_028894033.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011179101.1 12 MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6936 "Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)" XP_028897122.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011178582.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011177118.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-432720 "WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis" XP_028895193.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011190707.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_028897776.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_028895807.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028899881.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011178738.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_011188852.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011191899.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_011178989.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_011196725.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011190704.1 4 Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519 "Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression" XP_011182819.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_011192531.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_011187288.1 13 KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-8086;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2 "Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism" XP_011176484.1 3 Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_011184101.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_028896711.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011183366.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011197101.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011184511.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_028897701.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_011196211.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_028896579.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011183422.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_011195745.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193518.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011190055.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_011193673.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_011191098.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011184730.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_011186612.1 13 MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Purine metabolism" XP_011190460.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011186889.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_011177799.1 6 MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11 "Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_011187954.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions" XP_011187946.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_011186568.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424 "SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling" XP_028901520.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555 "MET receptor recycling";"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1" XP_011194787.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_028893874.1 7 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-983168 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011177835.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_011188038.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_028894883.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700 "MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_028894160.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_011195442.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_011184043.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_011188399.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination" XP_011188259.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_011196051.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I" XP_028901298.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011192015.1 4 KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_011176523.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_028900900.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028899740.1 6 MetaCyc: PWY-622;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-7900 "Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_028895338.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418594 "Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation";"G alpha (i) signalling events" XP_028894962.1 7 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_011185762.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011182532.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_011182300.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism" XP_011181241.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_028895594.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_011196999.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_028898052.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011177566.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011190609.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028897578.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839 "Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE" XP_011177834.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;MetaCyc: PWY-7511 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Protein ubiquitination" XP_011177588.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_028895360.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011191267.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011195123.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_011197066.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011180926.1 13 Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-3928665 "MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells" XP_011195452.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028898834.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_028901203.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_028898334.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011193965.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_028893652.1 22 Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011190500.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011181567.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_011193010.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation" XP_011192687.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_011186475.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_011178912.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_028896462.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028901082.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_011178674.1 8 Reactome: R-HSA-73614;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-7193 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I" XP_011179938.1 6 KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368 "Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_028898291.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_011187688.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_011185704.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_028894696.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_028897535.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_011183408.1 10 KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7198;MetaCyc: PWY-7210;Reactome: R-HSA-69205;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-3841;MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate" XP_011186926.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178408.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_011196444.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028897401.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" YP_004891175.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011189067.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011183752.1 7 KEGG: 00730+3.6.1.15;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545 "Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_011187104.1 11 Reactome: R-HSA-5689880;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161 "Ub-specific processing proteases";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation" XP_011187251.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011194713.1 4 KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" XP_011192674.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_011189209.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_011179896.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_011186505.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_011185490.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011183252.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011190527.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway" XP_028902129.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011187276.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport" XP_011181036.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_011184453.1 22 MetaCyc: PWY-621;Reactome: R-HSA-70263;MetaCyc: PWY-8013;Reactome: R-HSA-70171;MetaCyc: PWY-5054;MetaCyc: PWY-6981;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-3801;MetaCyc: PWY-7347;MetaCyc: PWY-622;MetaCyc: PWY-5659;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5514;KEGG: 00010+5.3.1.9;KEGG: 00520+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-6992;Reactome: R-HSA-6798695;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-5384 "Sucrose degradation III (sucrose invertase)";"Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis";"D-sorbitol biosynthesis I";"Chitin biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis III";"Starch biosynthesis";"GDP-mannose biosynthesis";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"TP53 Regulates Metabolic Genes";"1,5-anhydrofructose degradation";"Neutrophil degranulation";"Pentose phosphate pathway";"Sucrose biosynthesis II";"Sucrose degradation IV (sucrose phosphorylase)" XP_011189132.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes" XP_011194398.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011179601.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972 "mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_028894624.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_028898839.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011196295.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011194777.1 182 Reactome: R-HSA-5655862;Reactome: R-HSA-8849469;Reactome: R-HSA-8875360;Reactome: R-HSA-6782135;Reactome: R-HSA-2979096;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-937042;Reactome: R-HSA-8939902;Reactome: R-HSA-5675221;Reactome: R-HSA-9604323;Reactome: R-HSA-1169408;Reactome: R-HSA-205043;Reactome: R-HSA-5654733;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-450321;Reactome: R-HSA-195253;Reactome: R-HSA-168638;Reactome: R-HSA-977225;Reactome: R-HSA-2173788;Reactome: R-HSA-975144;Reactome: R-HSA-1169091;Reactome: R-HSA-5675482;Reactome: R-HSA-5632684;Reactome: R-HSA-6804757;Reactome: R-HSA-917937;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5654726;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-8948751;Reactome: R-HSA-5693565;Reactome: R-HSA-2644606;Reactome: R-HSA-9014325;Reactome: R-HSA-179409;Reactome: R-HSA-9636383;Reactome: R-HSA-162588;Reactome: R-HSA-5696397;Reactome: R-HSA-983168;Reactome: R-HSA-192823;Reactome: R-HSA-201681;Reactome: R-HSA-5693607;Reactome: R-HSA-75815;Reactome: R-HSA-174490;Reactome: R-HSA-9013973;Reactome: R-HSA-2672351;Reactome: R-HSA-174113;Reactome: R-HSA-72689;Reactome: R-HSA-5654732;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-3785653;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9613829;Reactome: R-HSA-3134975;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-1295596;Reactome: R-HSA-5696394;Reactome: R-HSA-2559580;Reactome: R-HSA-937072;Reactome: R-HSA-5357905;Reactome: R-HSA-2467813;Reactome: R-HSA-9013507;Reactome: R-HSA-175474;Reactome: R-HSA-5656121;Reactome: R-HSA-1253288;Reactome: R-HSA-8876493;Reactome: R-HSA-5676590;Reactome: R-HSA-8856825;Reactome: R-HSA-901032;Reactome: R-HSA-168927;Reactome: R-HSA-2559585;Reactome: R-HSA-72702;Reactome: R-HSA-5696395;Reactome: R-HSA-180585;Reactome: R-HSA-937039;Reactome: R-HSA-202424;Reactome: R-HSA-1236382;Reactome: R-HSA-2565942;Reactome: R-HSA-1358803;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-110312;Reactome: R-HSA-532668;Reactome: R-HSA-5654727;Reactome: R-HSA-2173795;Reactome: R-HSA-174048;Reactome: R-HSA-2173791;Reactome: R-HSA-168928;Reactome: R-HSA-5658442;Reactome: R-HSA-5656169;Reactome: R-HSA-8948747;Reactome: R-HSA-8854050;Reactome: R-HSA-209543;Reactome: R-HSA-9033241;Reactome: R-HSA-6781823;Reactome: R-HSA-1236974;Reactome: R-HSA-8863795;Reactome: R-HSA-9615710;Reactome: R-HSA-72764;Reactome: R-HSA-6781827;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-2691232;Reactome: R-HSA-8866654;Reactome: R-HSA-9637628;Reactome: R-HSA-2122947;Reactome: R-HSA-69231;Reactome: R-HSA-5362768;Reactome: R-HSA-6804756;Reactome: R-HSA-182971;Reactome: R-HSA-156827;Reactome: R-HSA-5607761;Reactome: R-HSA-450302;Reactome: R-HSA-72649;Reactome: R-HSA-349425;Reactome: R-HSA-5357956;Reactome: R-HSA-5689896;Reactome: R-HSA-1234176;Reactome: R-HSA-936440;Reactome: R-HSA-2122948;Reactome: R-HSA-5205685;Reactome: R-HSA-975163;Reactome: R-HSA-110314;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-209560;Reactome: R-HSA-937041;Reactome: R-HSA-2894862;Reactome: R-HSA-69541;Reactome: R-HSA-975110;Reactome: R-HSA-912631;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-9645460;Reactome: R-HSA-69017;Reactome: R-HSA-5689877;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-5685942;Reactome: R-HSA-4608870;Reactome: R-HSA-3322077;Reactome: R-HSA-445989;Reactome: R-HSA-6782210;Reactome: R-HSA-975957;Reactome: R-HSA-9646399;Reactome: R-HSA-6783310;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-4641263;Reactome: R-HSA-69481;Reactome: R-HSA-6804760;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-936964;Reactome: R-HSA-174084;Reactome: R-HSA-2173796;Reactome: R-HSA-8866652;Reactome: R-HSA-975956;Reactome: R-HSA-400253;Reactome: R-HSA-917729;Reactome: R-HSA-1799339;Reactome: R-HSA-5689901;Reactome: R-HSA-9633012;Reactome: R-HSA-68827;Reactome: R-HSA-8941858 "Translesion synthesis by POLK";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"InlB-mediated entry of Listeria monocytogenes into host cell";"Dual incision in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"IRAK2 mediated activation of TAK1 complex";"Regulation of RUNX2 expression and activity";"Negative regulation of MAPK pathway";"Negative regulation of NOTCH4 signaling";"ISG15 antiviral mechanism";"NRIF signals cell death from the nucleus";"Negative regulation of FGFR4 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of beta-catenin by the destruction complex";"NOD1/2 Signaling Pathway";"Amyloid fiber formation";"Downregulation of TGF-beta receptor signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"Regulation of necroptotic cell death";"Hedgehog 'on' state";"Regulation of TP53 Degradation";"Iron uptake and transport";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of FGFR1 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of PTEN stability and activity";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TICAM1,TRAF6-dependent induction of TAK1 complex";"APC-Cdc20 mediated degradation of Nek2A";"Prevention of phagosomal-lysosomal fusion";"Budding and maturation of HIV virion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Antigen processing: Ubiquitination & Proteasome degradation";"Viral mRNA Translation";"TCF dependent signaling in response to WNT";"Processing of DNA double-strand break ends";"Ubiquitin-dependent degradation of Cyclin D";"Membrane binding and targetting of GAG proteins";"TICAM1-dependent activation of IRF3/IRF7";"Stimuli-sensing channels";"SCF-beta-TrCP mediated degradation of Emi1";"Formation of a pool of free 40S subunits";"Negative regulation of FGFR3 signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Myoclonic epilepsy of Lafora";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Chaperone Mediated Autophagy";"Regulation of innate immune responses to cytosolic DNA";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Spry regulation of FGF signaling";"DNA Damage Recognition in GG-NER";"Oxidative Stress Induced Senescence";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of TNFR1 signaling";"Separation of Sister Chromatids";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Assembly Of The HIV Virion";"Translesion synthesis by POLI";"Downregulation of ERBB4 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"NIK-->noncanonical NF-kB signaling";"Cargo recognition for clathrin-mediated endocytosis";"ER Quality Control Compartment (ERQC)";"TICAM1, RIP1-mediated IKK complex recruitment";"Oncogene Induced Senescence";"Ribosomal scanning and start codon recognition";"Formation of Incision Complex in GG-NER";"Vif-mediated degradation of APOBEC3G";"IRAK1 recruits IKK complex";"Downstream TCR signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of PLK1 Activity at G2/M Transition";"Downregulation of ERBB2:ERBB3 signaling";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translesion synthesis by REV1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of FGFR2 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of RAS by GAPs";"Termination of translesion DNA synthesis";"Regulation of PTEN localization";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"p75NTR recruits signalling complexes";"Peroxisomal protein import";"Formation of TC-NER Pre-Incision Complex";"ER-Phagosome pathway";"Downregulation of ERBB2 signaling";"Late endosomal microautophagy";"Eukaryotic Translation Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"Modulation by Mtb of host immune system";"NOTCH1 Intracellular Domain Regulates Transcription";"Cyclin D associated events in G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of TP53 Activity through Phosphorylation";"EGFR downregulation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Dectin-1 mediated noncanonical NF-kB signaling";"activated TAK1 mediates p38 MAPK activation";"Translation initiation complex formation";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR1-induced NFkappaB signaling pathway";"Ovarian tumor domain proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulators of DDX58/IFIH1 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Pink/Parkin Mediated Mitophagy";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Recognition of DNA damage by PCNA-containing replication complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"NF-kB is activated and signals survival";"IKK complex recruitment mediated by RIP1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Stabilization of p53";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of signaling by CBL";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"Defective CFTR causes cystic fibrosis";"Alpha-protein kinase 1 signaling pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Josephin domain DUBs";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"HDR through Homologous Recombination (HRR)";"Asymmetric localization of PCP proteins";"Glycogen synthesis";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Aggrephagy";"Fanconi Anemia Pathway";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of FZD by ubiquitination";"G2/M Checkpoints";"Regulation of TP53 Activity through Methylation";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"UCH proteinases";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Autodegradation of Cdh1 by Cdh1:APC/C";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Circadian Clock";"Endosomal Sorting Complex Required For Transport (ESCRT)";"SRP-dependent cotranslational protein targeting to membrane";"Metalloprotease DUBs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity" XP_011176759.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011194010.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_028893650.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558 "RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011191915.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_028898753.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_028900605.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_028899049.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011176920.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011182931.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148 "Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011186428.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178761.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011181620.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028899365.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_028901001.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation" XP_011187732.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_011188353.1 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177 "Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II" XP_028901837.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_011182291.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028895528.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_028901795.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028901477.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011197138.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_011187958.2 6 Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110357 "Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1" XP_011189640.1 10 MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-5030;Reactome: R-HSA-196757 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"L-histidine degradation III";"Metabolism of folate and pterines" XP_011186020.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_011187956.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions" XP_028894512.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011194868.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011177166.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway" XP_028894338.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895668.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378 "PKA activation";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling" XP_011196553.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_028900737.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_028896397.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011181309.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-176034 "HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins" XP_011184813.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011190779.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_011177097.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_028897819.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011197013.1 6 KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780 "Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism" XP_011181706.1 7 Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381042 "ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression" XP_011182087.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_011192286.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_011185815.1 29 Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-3371511;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-69473 "Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"HSF1 activation";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint" XP_028898019.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011179772.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_011180536.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_011191580.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_028895460.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558 "Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011177115.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011185629.1 3 Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_011197110.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_011189119.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_028896534.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011191678.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_028895666.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_011190567.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011178473.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-68949 "Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Neddylation";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Orc1 removal from chromatin" XP_028894346.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_011178887.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011179547.1 10 KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096 "Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"HS-GAG degradation" XP_011190645.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Degradation of AXIN";"Regulation of PTEN stability and activity";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_028901886.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_011197065.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_028898874.1 6 MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122 "Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis" XP_011178485.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_028900380.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011178199.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011186256.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_011180140.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_011189870.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011191594.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_011191194.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011191427.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028894614.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011190012.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_011191613.1 14 MetaCyc: PWY-7254;MetaCyc: PWY-6728;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403 "TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)" XP_011190547.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_011183883.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-5683826 "Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine salvage";"Surfactant metabolism" XP_011188629.1 5 KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336;Reactome: R-HSA-6798695 "Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation" XP_011177103.1 7 MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-31;Reactome: R-HSA-70635 "Urea cycle";"Arginine biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Canavanine degradation";"Urea cycle" XP_011182431.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_011196434.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_028897539.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_011189991.1 23 Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392170 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12" XP_011185267.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011187962.1 17 Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-1834949;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3270619;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Cytosolic sensors of pathogen-associated DNA";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRF3-mediated induction of type I IFN";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_028896198.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926 "G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_011188826.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011192089.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_011179910.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3301854 "Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly" XP_011184519.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_028894242.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011185588.1 13 Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928662 "NRAGE signals death through JNK";"Rho GTPase cycle";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"MAPK6/MAPK4 signaling";"Human immunodeficiency virus 1 infection";"EPHB-mediated forward signaling" XP_028899710.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011196996.1 9 Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_011184516.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_028897538.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_011182151.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_011186523.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_011179521.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011196875.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_028899560.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193741.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_011195746.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899909.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_011190599.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011186901.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011184583.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_011184437.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_011176619.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011193669.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_028898035.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_028897138.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011182707.1 4 KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17 "Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis" XP_011185471.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)" XP_011187340.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_011179286.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_011177004.1 3 Reactome: R-HSA-936837;KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "Ion transport by P-type ATPases";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_028900526.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028900548.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_011189141.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_011182072.1 6 Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6" XP_028898521.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_011179666.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_011187153.2 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_011179520.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113 "Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Neutrophil degranulation";"Degradation of AXIN";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1" XP_011177578.1 12 MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-6708;Reactome: R-HSA-2142789 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis" XP_011180429.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_011189457.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation" XP_011190666.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_011191779.1 8 KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-74217 "Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine salvage" XP_028894205.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028899896.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011180647.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_011177838.1 10 Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459 "Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_011196216.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378 "Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling" XP_011186294.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_011191760.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_028901601.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_011176954.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_011194252.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011194236.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_011186796.1 9 MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70263 "Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis" XP_011186038.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011193905.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_011193465.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_011187085.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028902159.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011197046.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011193273.2 9 MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_011187813.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011196997.1 13 Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809 "Ca2+ pathway";"DAG and IP3 signaling";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization" XP_011187264.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028900135.1 83 Reactome: R-HSA-8865999;Reactome: R-HSA-2219530;Reactome: R-HSA-74749;Reactome: R-HSA-9026519;Reactome: R-HSA-8875360;Reactome: R-HSA-8875555;Reactome: R-HSA-8853334;Reactome: R-HSA-5654733;Reactome: R-HSA-5655253;Reactome: R-HSA-5663213;Reactome: R-HSA-1433559;Reactome: R-HSA-5673001;Reactome: R-HSA-5654720;Reactome: R-HSA-1839117;Reactome: R-HSA-2730905;Reactome: R-HSA-5654710;Reactome: R-HSA-112412;Reactome: R-HSA-9028731;Reactome: R-HSA-2424491;Reactome: R-HSA-9634285;Reactome: R-HSA-2179392;Reactome: R-HSA-182971;Reactome: R-HSA-5654700;Reactome: R-HSA-5654726;Reactome: R-HSA-2029482;Reactome: R-HSA-5654706;Reactome: R-HSA-389359;Reactome: R-HSA-2428933;Reactome: R-HSA-5654695;Reactome: R-HSA-8851805;Reactome: R-HSA-5655302;Reactome: R-HSA-391160;Reactome: R-HSA-210993;Reactome: R-HSA-5654704;Reactome: R-HSA-5654732;Reactome: R-HSA-9034864;Reactome: R-HSA-5654693;Reactome: R-HSA-5654719;Reactome: R-HSA-1295596;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-9028335;Reactome: R-HSA-8983432;Reactome: R-HSA-1257604;Reactome: R-HSA-167044;Reactome: R-HSA-109704;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-74751;Reactome: R-HSA-6811558;Reactome: R-HSA-5637810;Reactome: R-HSA-1250196;Reactome: R-HSA-9645135;Reactome: R-HSA-5654699;Reactome: R-HSA-8851907;Reactome: R-HSA-375165;Reactome: R-HSA-5654712;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-2871809;Reactome: R-HSA-388841;Reactome: R-HSA-180292;Reactome: R-HSA-5654688;Reactome: R-HSA-5654689;Reactome: R-HSA-8856825;Reactome: R-HSA-180336;Reactome: R-HSA-983695;Reactome: R-HSA-912526;Reactome: R-HSA-1236382;Reactome: R-HSA-8853338;Reactome: R-HSA-8875656;Reactome: R-HSA-1963640;Reactome: R-HSA-9027284;Reactome: R-HSA-6807004;Reactome: R-HSA-2871796;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-5655291;Reactome: R-HSA-8856828;Reactome: R-HSA-9607240;Reactome: R-HSA-512988;Reactome: R-HSA-1250347;Reactome: R-HSA-5654727 "MET activates PTPN11";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signal attenuation";"Activated NTRK2 signals through RAS";"InlB-mediated entry of Listeria monocytogenes into host cell";"MET activates RAP1 and RAC1";"Signaling by FGFR3 fusions in cancer";"Negative regulation of FGFR4 signaling";"Signaling by FGFR2 in disease";"RHO GTPases Activate WASPs and WAVEs";"Regulation of KIT signaling";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR4";"Signaling by cytosolic FGFR1 fusion mutants";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI-3K cascade:FGFR3";"SOS-mediated signalling";"Activated NTRK2 signals through FRS2 and FRS3";"DAP12 signaling";"Constitutive Signaling by Overexpressed ERBB2";"EGFR Transactivation by Gastrin";"EGFR downregulation";"FRS-mediated FGFR2 signaling";"Negative regulation of FGFR1 signaling";"Regulation of actin dynamics for phagocytic cup formation";"FRS-mediated FGFR3 signaling";"CD28 dependent Vav1 pathway";"SHC-related events triggered by IGF1R";"PI-3K cascade:FGFR2";"MET activates RAS signaling";"Signaling by FGFR1 in disease";"Signal regulatory protein family interactions";"Tie2 Signaling";"SHC-mediated cascade:FGFR3";"Negative regulation of FGFR3 signaling";"Activated NTRK3 signals through RAS";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR4";"Spry regulation of FGF signaling";"Downstream signal transduction";"Regulation of signaling by CBL";"Activated NTRK2 signals through PI3K";"Interleukin-15 signaling";"PIP3 activates AKT signaling";"Signalling to RAS";"PI3K Cascade";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Insulin receptor signalling cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by EGFRvIII";"SHC1 events in ERBB2 signaling";"STAT5 Activation";"SHC-mediated cascade:FGFR2";"MET activates PI3K/AKT signaling";"NCAM signaling for neurite out-growth";"FRS-mediated FGFR4 signaling";"RET signaling";"Signaling by SCF-KIT";"FCERI mediated Ca+2 mobilization";"Costimulation by the CD28 family";"GAB1 signalosome";"SHC-mediated cascade:FGFR1";"PI-3K cascade:FGFR1";"Cargo recognition for clathrin-mediated endocytosis";"SHC1 events in EGFR signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Interleukin receptor SHC signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by FGFR3 point mutants in cancer";"MET receptor recycling";"GRB2 events in ERBB2 signaling";"Erythropoietin activates RAS";"Negative regulation of MET activity";"FCERI mediated MAPK activation";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by FGFR4 in disease";"Clathrin-mediated endocytosis";"FLT3 Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB4 signaling";"Negative regulation of FGFR2 signaling" XP_011178491.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011186479.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_011177559.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011190431.1 5 MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_011179376.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_011181413.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011190537.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011192846.1 20 MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7291 "6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)" XP_011194292.1 3 KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism" XP_011180173.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011188901.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011190246.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_011179775.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011184183.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_011191094.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_028894221.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028896332.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011187070.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011191989.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_028901542.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1 "Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_011186558.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_028895311.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_011182308.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_011191515.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011181038.1 5 Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes" XP_028893610.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_028893589.1 14 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.42;Reactome: R-HSA-75896;MetaCyc: PWY-7411;MetaCyc: PWY-8055;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.15 "Glycerolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Peroxisomal protein import";"Glycerophospholipid metabolism" XP_028900993.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657 "NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes" XP_028894163.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_011181780.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_011193751.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_028894953.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_011177087.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028901174.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011185945.1 57 Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-532668;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425 "Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1" XP_011184314.1 3 Reactome: R-HSA-189085;Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011190566.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011191034.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011191748.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_011179293.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_011182669.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011180780.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_011194253.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011187508.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_028894407.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_028900449.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011193559.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_028899698.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011180367.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011189502.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_011181394.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590 "Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling" XP_011188882.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_011196231.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011189120.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_011195756.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011183879.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011177250.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028898876.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632 "O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_011185176.1 11 Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-72163;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_011195550.1 17 MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-6609;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6627 "Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Salinosporamide A biosynthesis" XP_011191070.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011193000.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011177343.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011177739.1 5 MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653 "Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_011185698.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011192887.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425 "CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1" XP_011181961.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028894738.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011187455.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011176952.1 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_028895889.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_028893796.1 10 MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5849 "Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis" XP_011190851.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_011180767.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011196907.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028896080.1 6 Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_011179937.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_028897823.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_028894801.1 57 Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells" XP_028898945.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_011193043.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011187105.1 11 Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953 "HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_028901277.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781 "Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression" XP_011182580.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-75893;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-193692 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"TNF signaling";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Regulated proteolysis of p75NTR" XP_028893882.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_028899328.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_028893609.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011178846.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_011193063.1 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7726 "Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_011178729.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_028899682.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011182676.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_028893452.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_011195724.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_011186690.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028899760.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555 "Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events" XP_011177497.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_028898707.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028901379.1 12 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling" XP_011190193.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028900734.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_011193671.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_011193039.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011190331.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_028898072.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_028899558.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178136.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism" XP_028898828.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011189116.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_028899048.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011185202.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_028900902.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011185646.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001 "Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism" XP_028895948.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011180491.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028898365.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_028896335.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011196240.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_011188947.1 9 Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_028899361.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_011196309.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011192118.1 4 MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75 "Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_011181321.1 16 Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1251985;Reactome: R-HSA-1250342;Reactome: R-HSA-1963640;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-1250347;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394 "ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Nuclear signaling by ERBB4";"PI3K events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB4 signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Signaling by ERBB4" XP_011195771.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011178622.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011179815.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011182923.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_028902103.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-432040 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_011185160.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011183162.1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-193681;Reactome: R-HSA-5626978 "Glycosphingolipid metabolism";"Ceramide signalling";"TNFR1-mediated ceramide production" XP_011177047.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits" XP_011183531.1 5 Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042 "Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle" XP_011182678.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_011181346.1 1 Reactome: R-HSA-419771 "Opsins" XP_028895302.1 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate" XP_011185626.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011195686.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011177453.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028899702.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011181592.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011181591.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028894598.1 5 Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_011177267.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011182855.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR" XP_011196638.1 5 MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I" XP_011194274.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" XP_011188044.1 7 MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism" XP_011189316.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_011187324.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011179482.1 5 KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis" XP_011176911.1 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_028898829.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011190081.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011177828.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_011186850.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_011180537.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_028897077.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011187359.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011178255.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_028897157.1 32 Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-9018519 "Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression" XP_011197049.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028900729.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_028901568.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_011188046.1 13 MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9 "L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Folate polyglutamylation";"One carbon pool by folate";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate" XP_028897635.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011196462.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_011191617.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_011184906.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_011190857.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_028902229.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_011179487.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011191199.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_011179477.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011191917.1 4 Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895 "Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis" XP_028896200.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926 "G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_011196139.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_028894949.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_011182912.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191 "Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PC" XP_011189633.1 11 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane" XP_011193893.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011187621.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_011193152.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039 "Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex" XP_011186471.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_011181462.1 16 Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-166058;Reactome: R-HSA-3134963;Reactome: R-HSA-975138;Reactome: R-HSA-209543;Reactome: R-HSA-975110;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-5602498;Reactome: R-HSA-1257604 "IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"p75NTR recruits signalling complexes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"PIP3 activates AKT signaling" XP_028901137.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_011176944.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011195580.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_011192704.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_028897719.1 5 KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3 "Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes" XP_011178209.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination" XP_011183741.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_011190596.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011194855.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_028896282.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028896842.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_011193480.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_011191909.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_028899283.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011185031.1 5 Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000 "Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"RAF activation" XP_011187626.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011191807.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011178180.1 17 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_011187108.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_028894354.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_011192111.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_011182042.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_011185161.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028894138.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011179850.1 10 Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;MetaCyc: PWY-7849;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695 "Non-integrin membrane-ECM interactions";"Purine metabolism";"Retinoid cycle disease events";"Amyloid fiber formation";"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation" XP_011188197.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028894638.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_011182369.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379 "Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres" XP_011179326.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_011182148.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_028898162.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_028900078.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_028898607.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_011187161.1 6 MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085 "Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate" XP_011187574.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis" XP_011193124.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011194794.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_011179647.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases" XP_028894380.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" XP_011178714.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_028896205.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028896130.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028897789.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_028896605.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation" XP_011190061.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_011188486.1 15 Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939 "HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)" XP_011192059.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878 "Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport" XP_028900492.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011178118.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_011193718.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_028898635.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_028897975.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011183314.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_028894194.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028901838.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_011193356.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_011183291.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011193016.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_011182682.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_011183737.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011191932.1 8 MetaCyc: PWY-7573;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5739 "GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis" XP_011180441.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011189552.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-983712 "Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Ion channel transport" XP_011190501.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011192907.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011177035.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_011190490.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028894531.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011190571.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011182938.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011196708.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_028900002.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295 "Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"MHC class II antigen presentation" XP_011193900.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028899406.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184 "Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_028900575.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_028893969.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_028894872.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_011183115.1 5 MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_011183315.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_028898794.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_011192543.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_028894389.1 10 MetaCyc: PWY-7003;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1 "Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis" XP_011182222.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_011182044.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_011186277.1 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_011195711.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_011191443.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_028895271.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011185837.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011176745.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_028894264.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_028896716.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_028900327.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011197098.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028897116.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_011188794.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_011191643.2 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302 "Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)" XP_011186315.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028900007.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_028901572.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_011179466.1 18 Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167242 "RNA Polymerase II Transcription Elongation";"mRNA Capping";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_011181989.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_028901375.1 12 Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208 "Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling" XP_011193593.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_028896732.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011179783.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_011184057.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011196431.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_011184041.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_011196486.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_011187370.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_011182301.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_011195614.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011192007.1 3 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_011193293.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4 "Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism" XP_011180969.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_011188275.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_028894224.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011182068.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011181319.1 11 Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110314 "Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_011185754.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_011192982.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_028894157.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_011177226.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_011192208.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011187357.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028899360.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011185696.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_011184184.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_028901474.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011179378.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_011181105.1 20 MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7574 "6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II" XP_011191848.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011182965.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_011176494.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028896403.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011179315.1 18 MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7205 "Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation" XP_028896924.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_011179193.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_011187733.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011187566.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011179181.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011193677.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-438066 "HSF1-dependent transactivation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_011182900.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011180529.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_011194671.1 8 KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1 "Fructose and mannose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_011187838.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011190148.1 9 Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_011188432.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_028894463.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660 "Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway" XP_011182321.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011193285.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_011189473.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011196551.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011177490.1 11 Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1 "VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection" XP_011179817.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894663.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011188053.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_011187110.1 11 Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_028899352.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_028896075.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_011178278.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_011183119.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_011189572.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_011178254.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_028896243.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_011194055.1 5 KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_028895243.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011192566.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028896712.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_028896996.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_011188561.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011179861.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011195128.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011189307.1 6 Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-913709 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins" XP_028901973.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011189058.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-437239 "RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1" XP_011185650.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_028894161.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_028896847.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_011177846.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_011193909.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_028893659.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria" XP_028897499.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_011182147.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028901678.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011186344.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_011190373.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage" XP_011196930.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_011178182.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011192012.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_011190942.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling" XP_011177830.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_011188173.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_011179407.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_028895339.1 11 Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660 "Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway" XP_011181868.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"T cell receptor signaling pathway" XP_011178677.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028894170.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_011177907.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011178117.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_028896369.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_028901075.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_011192427.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_011182562.1 6 KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484 "Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_028900220.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51 "Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Glycerophospholipid metabolism" XP_028901513.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I" XP_011181186.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_028895873.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_011177637.1 5 Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex" XP_028896359.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011187955.1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen chain trimerization" XP_011180649.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_028897773.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011196776.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_011191264.1 5 Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-5358346 "XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis" XP_011187378.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_028900547.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_011195688.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011178638.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_011186688.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011181265.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011193348.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_011178477.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011192912.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_011190013.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_011190743.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011180259.1 5 Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-917937 "Neddylation";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport" XP_011189004.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_011181649.1 6 KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395 "Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation" XP_028897237.1 11 Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-5610787 "G alpha (s) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Hedgehog 'off' state" XP_028894717.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification" XP_011192991.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_028901799.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011184049.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_028895199.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011187009.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_011178673.1 8 Reactome: R-HSA-73614;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-7193 "Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I" XP_028897408.1 3 Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13 "G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_011189231.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13 "Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism" XP_028895761.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_028897351.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_011177576.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011192109.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_011196023.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028899457.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028895890.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_028894213.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011187976.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_011185182.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028897642.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_011188968.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011185567.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_011187580.1 56 Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_011194964.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011191081.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_028896679.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011186300.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_011180449.1 52 Reactome: R-HSA-749476;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-73762;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_028899162.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028894472.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_028896092.1 3 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" XP_011196777.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_011185270.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_011189121.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_011192980.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011183478.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011180442.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028897318.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_011187573.1 4 KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922 "Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis" XP_011186885.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_011196789.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011183161.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_011191190.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_011192522.1 5 Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_028897807.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011195876.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_028901827.1 17 KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-6608;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-5532;MetaCyc: PWY-4202 "Purine metabolism";"Purine catabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)" XP_011188223.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011179878.2 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_011197010.1 13 Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802955 "Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_011185072.1 11 MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6963;MetaCyc: PWY-6964;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210455 "L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism" XP_011183949.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011187290.1 13 MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-6969 "Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_011187584.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_011190584.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011189051.1 7 MetaCyc: PWY-6855;Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906 "Chitin degradation I (archaea)";"Pentose phosphate pathway";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_011178731.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_011178412.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_028898669.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_028901998.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417 "Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" XP_028895591.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_011182024.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_028900847.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_011187980.1 4 KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I" XP_011177210.1 5 Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_011184550.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_011191820.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_011193907.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_011180366.1 20 KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724 "Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"Human papillomavirus infection";"Amino acids regulate mTORC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription" XP_011181361.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_011191444.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_028900815.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011192003.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_028899112.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011187072.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_028897466.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011180603.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011179732.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes" XP_028895626.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246 "Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript" XP_028893469.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011192567.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011189074.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_011193517.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_028897836.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_028898288.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011190188.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011187638.1 30 Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-2894862;Reactome: R-HSA-5610785;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-917937;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264 "Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"Iron uptake and transport";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation" XP_028896715.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_011189228.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559 "Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway" XP_028894244.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011189372.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_011187371.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011185761.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011195468.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028893911.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_011177206.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011193019.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_011190191.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011191144.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_011192819.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_011182299.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_011187197.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_011183164.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011186852.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_011196768.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011191672.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011188795.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011182374.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011192203.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_028895817.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028894963.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-5673001 "Neutrophil degranulation";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade" XP_011179220.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028896688.1 19 KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383 "Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Gluconeogenesis";"Pyruvate metabolism";"Methane metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_011179761.1 24 Reactome: R-HSA-2871837;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;Reactome: R-HSA-202424;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;Reactome: R-HSA-444257;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400 "FCERI mediated NF-kB activation";"Integrin signaling";"VEGFR2 mediated vascular permeability";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"Downstream TCR signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"PIP3 activates AKT signaling";"RSK activation";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer" XP_011189844.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011190761.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_028897390.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011187878.1 8 Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159 "HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling" XP_011191706.2 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_028893906.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011176574.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_028901307.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028897894.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_011194956.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011196718.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" XP_011184033.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_011192242.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011180756.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011180407.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424 "SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling" XP_011181035.1 5 Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events" XP_028896663.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_028895366.1 11 Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2 "Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway" XP_011181784.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" XP_028897317.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_011182018.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403 "Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling" XP_011191280.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178396.1 29 Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-5696395 "RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER" XP_028901924.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "tRNA processing in the nucleus";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_011188322.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_028901927.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_011179884.1 15 MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-6886 "Rubisco shunt";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)" XP_011190447.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011179271.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_028898447.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_011182529.1 26 Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483 "Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"Activation of AMPK downstream of NMDARs" XP_011178080.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_011191949.1 3 KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3 "Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism" XP_011177053.1 5 Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662 "VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling" XP_028895954.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011195121.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011190607.1 4 KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558 "Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine" XP_028895300.1 6 MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900 "Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_011192390.1 83 Reactome: R-HSA-512988;Reactome: R-HSA-1250347;Reactome: R-HSA-5654727;Reactome: R-HSA-9607240;Reactome: R-HSA-2871796;Reactome: R-HSA-6807004;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-8856828;Reactome: R-HSA-5655291;Reactome: R-HSA-9027284;Reactome: R-HSA-1963640;Reactome: R-HSA-912526;Reactome: R-HSA-8875656;Reactome: R-HSA-1236382;Reactome: R-HSA-8853338;Reactome: R-HSA-8856825;Reactome: R-HSA-5654689;Reactome: R-HSA-180336;Reactome: R-HSA-983695;Reactome: R-HSA-388841;Reactome: R-HSA-2871809;Reactome: R-HSA-5654688;Reactome: R-HSA-180292;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-375165;Reactome: R-HSA-5654712;Reactome: R-HSA-5637810;Reactome: R-HSA-6811558;Reactome: R-HSA-5654699;Reactome: R-HSA-1250196;Reactome: R-HSA-9645135;Reactome: R-HSA-8851907;Reactome: R-HSA-109704;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-74751;Reactome: R-HSA-8983432;Reactome: R-HSA-167044;Reactome: R-HSA-1257604;Reactome: R-HSA-9028335;Reactome: R-HSA-9034864;Reactome: R-HSA-5654693;Reactome: R-HSA-5654719;Reactome: R-HSA-1295596;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-5654732;Reactome: R-HSA-210993;Reactome: R-HSA-5654704;Reactome: R-HSA-5655302;Reactome: R-HSA-391160;Reactome: R-HSA-2428933;Reactome: R-HSA-8851805;Reactome: R-HSA-5654695;Reactome: R-HSA-5654706;Reactome: R-HSA-389359;Reactome: R-HSA-2179392;Reactome: R-HSA-182971;Reactome: R-HSA-5654726;Reactome: R-HSA-5654700;Reactome: R-HSA-2029482;Reactome: R-HSA-2424491;Reactome: R-HSA-9634285;Reactome: R-HSA-5654710;Reactome: R-HSA-112412;Reactome: R-HSA-9028731;Reactome: R-HSA-5654720;Reactome: R-HSA-5673001;Reactome: R-HSA-1839117;Reactome: R-HSA-2730905;Reactome: R-HSA-1433559;Reactome: R-HSA-5654733;Reactome: R-HSA-8853334;Reactome: R-HSA-5655253;Reactome: R-HSA-5663213;Reactome: R-HSA-8875555;Reactome: R-HSA-74749;Reactome: R-HSA-9026519;Reactome: R-HSA-8875360;Reactome: R-HSA-8865999;Reactome: R-HSA-2219530 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB4 signaling";"Negative regulation of FGFR2 signaling";"FLT3 Signaling";"FCERI mediated MAPK activation";"Negative regulation of MET activity";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Clathrin-mediated endocytosis";"Signaling by FGFR4 in disease";"Erythropoietin activates RAS";"GRB2 events in ERBB2 signaling";"Interleukin receptor SHC signaling";"MET receptor recycling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by FGFR3 point mutants in cancer";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR1";"SHC1 events in EGFR signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Costimulation by the CD28 family";"FCERI mediated Ca+2 mobilization";"SHC-mediated cascade:FGFR1";"GAB1 signalosome";"RET signaling";"Signaling by SCF-KIT";"NCAM signaling for neurite out-growth";"FRS-mediated FGFR4 signaling";"Constitutive Signaling by EGFRvIII";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-mediated cascade:FGFR2";"SHC1 events in ERBB2 signaling";"STAT5 Activation";"MET activates PI3K/AKT signaling";"PI3K Cascade";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Insulin receptor signalling cascade";"Interleukin-15 signaling";"Signalling to RAS";"PIP3 activates AKT signaling";"Activated NTRK2 signals through PI3K";"Activated NTRK3 signals through RAS";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR4";"Spry regulation of FGF signaling";"Downstream signal transduction";"Regulation of signaling by CBL";"Negative regulation of FGFR3 signaling";"Tie2 Signaling";"SHC-mediated cascade:FGFR3";"Signaling by FGFR1 in disease";"Signal regulatory protein family interactions";"SHC-related events triggered by IGF1R";"MET activates RAS signaling";"PI-3K cascade:FGFR2";"FRS-mediated FGFR3 signaling";"CD28 dependent Vav1 pathway";"EGFR Transactivation by Gastrin";"EGFR downregulation";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR2 signaling";"Regulation of actin dynamics for phagocytic cup formation";"DAP12 signaling";"Constitutive Signaling by Overexpressed ERBB2";"PI-3K cascade:FGFR3";"SOS-mediated signalling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR4";"RAF/MAP kinase cascade";"Signaling by cytosolic FGFR1 fusion mutants";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of KIT signaling";"Negative regulation of FGFR4 signaling";"Signaling by FGFR3 fusions in cancer";"Signaling by FGFR2 in disease";"RHO GTPases Activate WASPs and WAVEs";"MET activates RAP1 and RAC1";"Signal attenuation";"Activated NTRK2 signals through RAS";"InlB-mediated entry of Listeria monocytogenes into host cell";"MET activates PTPN11";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_011193609.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_011187793.1 12 Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-451308 "Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor" XP_028899461.1 20 MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;Reactome: R-HSA-75105;MetaCyc: PWY-7384;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5538;Reactome: R-HSA-1268020 "Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Mitochondrial protein import" XP_011190727.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_011178103.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_028894830.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113 "Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1" XP_028900984.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011179611.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_028896250.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_028896271.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_011177314.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_011181745.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028894124.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011176506.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_028896440.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_011188135.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_028898830.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028896396.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011190940.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_011185322.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_011182701.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011186350.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_011188862.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011194875.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028895471.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011190941.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling" XP_011186151.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011190938.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling" XP_028900903.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011178625.1 7 Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472 "HCMV Early Events";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011180020.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_011191124.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_028900834.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_028899187.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_011178588.1 57 Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684 "Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Neddylation";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state" XP_028897893.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_011186750.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_028899509.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_028901851.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_028895916.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011180777.1 11 Reactome: R-HSA-69231;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-2029482 "Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation" XP_011182767.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_011195627.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028894313.1 10 Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-427413 "MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression" XP_011179759.1 24 Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-444257;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1 "CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"Integrin signaling";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"RSK activation";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Downstream TCR signaling";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"RHO GTPases activate PKNs";"Activation of AKT2";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection" XP_011179604.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-6798695 "Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Neutrophil degranulation" XP_028899712.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_011188517.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_028899992.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_011183564.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_011187798.1 7 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I" XP_011195426.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011191844.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899002.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011187622.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins" XP_011189581.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_028897500.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_011179138.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028900376.1 8 Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_028895708.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011197145.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011176683.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321 "FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_011187664.1 3 Reactome: R-HSA-6807505;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011183955.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_011180129.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_011177259.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011180632.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011193200.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656 "TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling" XP_028901756.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_028895677.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011178743.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_011192714.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011181023.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_011191275.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_028896296.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_028901356.1 8 KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1 "Glycolysis / Gluconeogenesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Fructose and mannose metabolism" XP_011182880.1 29 MetaCyc: PWY-5076;MetaCyc: PWY-7111;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-6871;MetaCyc: PWY-5079;MetaCyc: PWY-5751;MetaCyc: PWY-6313;KEGG: 00625+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00071+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-5082;MetaCyc: PWY-6333;MetaCyc: PWY-6802;MetaCyc: PWY-5057;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-3162 "L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Glycine, serine and threonine metabolism";"Butanol and isobutanol biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Noradrenaline and adrenaline degradation";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Phenylethanol biosynthesis";"Serotonin degradation";"Chloroalkane and chloroalkene degradation";"Metabolism of xenobiotics by cytochrome P450";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"Drug metabolism - cytochrome P450";"Chitin degradation to ethanol";"Fatty acid degradation";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Glycolysis / Gluconeogenesis";"L-isoleucine degradation II";"L-methionine degradation III";"Acetaldehyde biosynthesis I";"Salidroside biosynthesis";"L-valine degradation II";"Tyrosine metabolism";"Pyruvate fermentation to ethanol III";"L-tryptophan degradation V (side chain pathway)" XP_011177639.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011196208.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_011193612.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_011193649.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011194342.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028895318.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011185561.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_011187249.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011196328.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-6369;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6362 "Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_011185615.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011178685.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_028901805.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011187081.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011183219.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-203927 "Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis" XP_011191401.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011181748.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011182902.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" XP_028901476.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011191715.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_011180775.1 11 Reactome: R-HSA-69231;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-2029482 "Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation" XP_028894523.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_011193047.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_028898118.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_011179156.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_011189605.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011188123.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_028894811.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_028898877.1 6 Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632 "O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_011187660.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_011180526.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_011181072.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_028893607.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028899637.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_011195799.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_011186352.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation" XP_028897367.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_011190606.1 4 Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism" XP_011176776.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011183423.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_028895474.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011186639.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_011194957.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_028894263.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011191850.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_028898771.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_028894511.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011196079.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041 "MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1" XP_011179528.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_011190273.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_028895368.1 11 KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-2029482 "T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation" XP_011191946.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011184438.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_028894933.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916 "MPS VII - Sly syndrome";"HS-GAG degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation" XP_011184099.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_028899790.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_011192127.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011178565.1 3 Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60 "Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation" XP_011186518.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs" XP_011185158.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011183126.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_028900730.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_011193736.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_028900140.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_011184585.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_011180519.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028897777.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_011178143.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011187174.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_028901453.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_011189286.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011193768.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_028896279.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011184046.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_011191096.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807 "T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling" XP_011190040.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_011188799.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011195667.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_028895865.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism" XP_028900841.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011182913.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028900752.1 19 Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046 "Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"Chylomicron clearance";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Chylomicron remodeling";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Platelet sensitization by LDL";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"VLDL clearance" XP_028900712.1 25 Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"HCMV Early Events";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic" XP_028902099.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_011195419.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_028896268.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_028900467.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028895736.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_011181595.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028895566.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011179561.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_011195763.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin" XP_028900746.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_028898023.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_028900740.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_028900782.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_011192820.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764 "Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Degradation of AXIN";"Neutrophil degranulation";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling" XP_011196038.1 6 KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599 "Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate" XP_028897837.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011187984.2 4 MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing" XP_028896473.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_028900254.1 13 Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_011193346.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011191011.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_028894932.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23 "Neutrophil degranulation";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" XP_011182528.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade" XP_011182544.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_028899785.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_011178571.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_011192380.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_028894462.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011186216.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_011177346.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_011193639.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011187837.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028900109.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028899733.1 9 MetaCyc: PWY-6983;MetaCyc: PWY-6703;MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-5663;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16 "Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis" XP_011190683.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_011188166.1 31 MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-7723;MetaCyc: PWY-6113;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-7746;MetaCyc: PWY-7858;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-6799;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-5989;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7664;Reactome: R-HSA-75105;MetaCyc: PWY-8047 "Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Bacterial bioluminescence";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis" XP_011186924.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_011196888.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028894779.1 10 Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148 "Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011194341.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011193789.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011193025.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_028894509.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_028893672.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_028893586.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_011188092.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_011181751.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_011177890.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_011180486.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_011177938.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011178899.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011191796.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_011195242.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028894919.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_028901531.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011177095.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_011188864.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011182760.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_011192393.1 83 Reactome: R-HSA-389359;Reactome: R-HSA-5654706;Reactome: R-HSA-5654695;Reactome: R-HSA-8851805;Reactome: R-HSA-2428933;Reactome: R-HSA-9634285;Reactome: R-HSA-2424491;Reactome: R-HSA-2029482;Reactome: R-HSA-5654700;Reactome: R-HSA-5654726;Reactome: R-HSA-182971;Reactome: R-HSA-2179392;Reactome: R-HSA-210993;Reactome: R-HSA-5654704;Reactome: R-HSA-5654732;Reactome: R-HSA-391160;Reactome: R-HSA-5655302;Reactome: R-HSA-8875555;Reactome: R-HSA-5663213;Reactome: R-HSA-5654733;Reactome: R-HSA-5655253;Reactome: R-HSA-8853334;Reactome: R-HSA-2219530;Reactome: R-HSA-8865999;Reactome: R-HSA-8875360;Reactome: R-HSA-9026519;Reactome: R-HSA-74749;Reactome: R-HSA-2730905;Reactome: R-HSA-1839117;Reactome: R-HSA-5673001;Reactome: R-HSA-5654720;Reactome: R-HSA-9028731;Reactome: R-HSA-112412;Reactome: R-HSA-5654710;Reactome: R-HSA-1433559;Reactome: R-HSA-1236382;Reactome: R-HSA-8853338;Reactome: R-HSA-8875656;Reactome: R-HSA-912526;Reactome: R-HSA-1963640;Reactome: R-HSA-983695;Reactome: R-HSA-180336;Reactome: R-HSA-8856825;Reactome: R-HSA-5654689;Reactome: R-HSA-9607240;Reactome: R-HSA-1250347;Reactome: R-HSA-5654727;Reactome: R-HSA-512988;Reactome: R-HSA-9027284;Reactome: R-HSA-8856828;Reactome: R-HSA-5655291;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-6807004;Reactome: R-HSA-2871796;Reactome: R-HSA-167044;Reactome: R-HSA-1257604;Reactome: R-HSA-8983432;Reactome: R-HSA-74751;Reactome: R-HSA-354194;Reactome: R-HSA-109704;Reactome: R-HSA-179812;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-1295596;Reactome: R-HSA-5654719;Reactome: R-HSA-5654693;Reactome: R-HSA-9034864;Reactome: R-HSA-9028335;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-180292;Reactome: R-HSA-5654688;Reactome: R-HSA-2871809;Reactome: R-HSA-388841;Reactome: R-HSA-8851907;Reactome: R-HSA-5654699;Reactome: R-HSA-1250196;Reactome: R-HSA-9645135;Reactome: R-HSA-5637810;Reactome: R-HSA-6811558;Reactome: R-HSA-5654712;Reactome: R-HSA-375165 "CD28 dependent Vav1 pathway";"FRS-mediated FGFR3 signaling";"PI-3K cascade:FGFR2";"MET activates RAS signaling";"SHC-related events triggered by IGF1R";"Constitutive Signaling by Overexpressed ERBB2";"DAP12 signaling";"Regulation of actin dynamics for phagocytic cup formation";"FRS-mediated FGFR2 signaling";"Negative regulation of FGFR1 signaling";"EGFR downregulation";"EGFR Transactivation by Gastrin";"Tie2 Signaling";"SHC-mediated cascade:FGFR3";"Negative regulation of FGFR3 signaling";"Signal regulatory protein family interactions";"Signaling by FGFR1 in disease";"MET activates RAP1 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR4 signaling";"Signaling by FGFR2 in disease";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET activates PTPN11";"InlB-mediated entry of Listeria monocytogenes into host cell";"Activated NTRK2 signals through RAS";"Signal attenuation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Signaling by cytosolic FGFR1 fusion mutants";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR4";"Activated NTRK2 signals through FRS2 and FRS3";"SOS-mediated signalling";"PI-3K cascade:FGFR3";"Regulation of KIT signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by FGFR3 point mutants in cancer";"MET receptor recycling";"Interleukin receptor SHC signaling";"GRB2 events in ERBB2 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"SHC1 events in EGFR signaling";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR1";"FLT3 Signaling";"SHC1 events in ERBB4 signaling";"Negative regulation of FGFR2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Erythropoietin activates RAS";"Clathrin-mediated endocytosis";"Signaling by FGFR4 in disease";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Negative regulation of MET activity";"FCERI mediated MAPK activation";"Signalling to RAS";"PIP3 activates AKT signaling";"Interleukin-15 signaling";"Insulin receptor signalling cascade";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI3K Cascade";"GRB2 events in EGFR signaling";"Downstream signal transduction";"Regulation of signaling by CBL";"Spry regulation of FGF signaling";"SHC-mediated cascade:FGFR4";"FRS-mediated FGFR1 signaling";"Activated NTRK3 signals through RAS";"Activated NTRK2 signals through PI3K";"Signaling by SCF-KIT";"RET signaling";"GAB1 signalosome";"SHC-mediated cascade:FGFR1";"FCERI mediated Ca+2 mobilization";"Costimulation by the CD28 family";"MET activates PI3K/AKT signaling";"SHC-mediated cascade:FGFR2";"SHC1 events in ERBB2 signaling";"STAT5 Activation";"Constitutive Signaling by EGFRvIII";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR4 signaling";"NCAM signaling for neurite out-growth" XP_011182953.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_011185822.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_028900728.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_028894950.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_028896353.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_028899976.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011193811.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_011191198.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_011184740.1 4 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_011178819.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011188407.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_011188307.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_011178829.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_011193850.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_011178444.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011183530.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288 "MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1" XP_028898404.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_011192934.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_028898022.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011193525.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011196931.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_028896398.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011185377.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_011179922.1 14 MetaCyc: PWY-3661;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-181;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622 "Glycine betaine degradation I";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Cyanoamino acid metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)" XP_028894207.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028894190.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011176546.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028895590.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_011196864.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_028894520.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_011193608.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_028894291.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_011185522.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011182354.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_011188351.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_011192008.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011176950.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"Thermogenesis";"Relaxin signaling pathway" XP_011191068.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_028896956.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_011177942.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_028897774.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_028901175.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011190409.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_028896464.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011182961.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_028899522.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_011185829.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011181521.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Stachyose degradation" XP_028896082.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011189470.2 1 Reactome: R-HSA-400253 "Circadian Clock" XP_028896371.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011195589.1 4 Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-156581 "rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"Methylation" XP_011178727.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_011189936.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_011184648.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011183817.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011183583.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028898689.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_011189030.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028893884.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_011186303.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_028894697.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_011192128.1 3 Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis" XP_011189639.1 10 MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-5030;Reactome: R-HSA-196757 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"L-histidine degradation III";"Metabolism of folate and pterines" XP_028896839.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-75815 "Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D" XP_011191062.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation" XP_028900831.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_028901919.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555 "Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events" XP_028894908.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_028895304.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011180765.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_028893530.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011190321.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases" XP_028900065.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011193685.2 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_028894290.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER" XP_011177069.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193203.1 6 MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation" XP_011192246.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011193188.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_028902131.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011192325.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011195620.1 1 Reactome: R-HSA-1632852 "Macroautophagy" YP_004891169.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011191010.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_028898051.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011190367.1 12 MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis" XP_011190861.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_028895321.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011177721.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II" XP_011190910.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_011195153.1 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_028900602.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011195463.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178357.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_011179278.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_011189306.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632 "O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_011195161.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_028895915.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_028896281.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011189762.1 5 Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-879415 "Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling" XP_011191789.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011183896.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011177168.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway" XP_011178707.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_028900612.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_028899369.1 17 KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743 "Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate cycle" XP_011192213.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011180659.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_011182581.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_011183309.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011177384.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_011185775.1 12 MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-7230;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5855 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_028899975.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_011189288.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011195789.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028899766.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_011184850.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_011190167.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_011185286.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_028901091.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_011189344.1 14 Reactome: R-HSA-2173788;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-69273 "Downregulation of TGF-beta receptor signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition" XP_011176810.1 24 Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-381676 "ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_011192065.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025 "Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation" XP_011184742.1 4 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_028897530.1 52 Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-73780;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167246 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Chain Elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript" XP_011196156.1 12 Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599 "Glycogen synthesis";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Stachyose degradation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_011189440.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" XP_011177900.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453 "Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response" XP_028897552.1 10 MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153 "3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection" XP_011181986.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_011196578.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_028899986.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_011196338.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011178439.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011178361.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096 "CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation" XP_011188917.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_028895754.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_011193615.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_028899640.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011188263.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-193692 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR" XP_028901276.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781 "Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression" XP_011189663.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_011188411.1 12 MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-196780;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism";"One carbon pool by folate" XP_011181256.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028893880.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_011177013.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028896721.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_028896980.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin" XP_028893855.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028896743.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_011177889.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_011194166.1 6 KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_011193486.1 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883 "Neutrophil degranulation";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG" XP_011176871.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_028901002.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657 "NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes" XP_011184677.1 18 MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-5532;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.3;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6644;MetaCyc: PWY-6608;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6627;KEGG: 00983+2.4.2.3;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611 "Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Pyrimidine catabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine metabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Salinosporamide A biosynthesis";"Drug metabolism - other enzymes";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V" XP_028899179.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011190778.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_028894226.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011185195.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028902121.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_011178245.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011179847.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011189029.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011197078.1 33 MetaCyc: PWY-6802;MetaCyc: PWY-6333;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7013;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-3162;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6587;MetaCyc: PWY-5057;KEGG: 00350+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-5082;MetaCyc: PWY-5078;MetaCyc: PWY-5480;KEGG: 00010+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00982+1.1.1.1;KEGG: 00626+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5751;MetaCyc: PWY-5079;MetaCyc: PWY-6871;Reactome: R-HSA-71384;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-7111;MetaCyc: PWY-5076 "Salidroside biosynthesis";"Acetaldehyde biosynthesis I";"Fatty acid degradation";"Chitin degradation to ethanol";"(S)-propane-1,2-diol degradation";"Chloroalkane and chloroalkene degradation";"Noradrenaline and adrenaline degradation";"Glycine, serine and threonine metabolism";"Protein S-nitrosylation and denitrosylation";"L-tryptophan degradation V (side chain pathway)";"Methane metabolism";"Pyruvate fermentation to ethanol III";"L-valine degradation II";"Tyrosine metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"L-methionine degradation III";"L-isoleucine degradation II";"Pyruvate fermentation to ethanol I";"Glycolysis / Gluconeogenesis";"Retinol metabolism";"Pyruvate fermentation to ethanol II";"Drug metabolism - cytochrome P450";"Naphthalene degradation";"Metabolism of xenobiotics by cytochrome P450";"Serotonin degradation";"Phenylethanol biosynthesis";"L-phenylalanine degradation III";"3-methylbutanol biosynthesis (engineered)";"Ethanol oxidation";"alpha-Linolenic acid metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"L-leucine degradation III" XP_011187352.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_011190531.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_028900211.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_011193450.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_011189229.1 10 MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism" XP_028900284.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_011184303.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028900001.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy" XP_011181939.1 4 Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4719377 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_028899884.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011185814.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_011179918.1 14 Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-181;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00680+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622 "Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Folate polyglutamylation";"Folate transformations II (plants)";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Methane metabolism";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)" XP_011192577.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_011184224.1 20 Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5685942 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)" XP_011188379.1 5 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_028901094.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-3000484 "VLDL assembly";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Clathrin-mediated endocytosis";"LDL clearance";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors" XP_011193230.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_011183569.1 7 MetaCyc: PWY-6471;Reactome: R-HSA-4549356;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13 "Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis" XP_011182188.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_011181582.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011184767.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_028896423.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_028898875.1 6 Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632 "O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_028898835.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011195513.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011196060.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51 "Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism" XP_028894474.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011184652.1 56 Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813 "Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids" XP_011182328.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011182318.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028900921.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism" XP_011189351.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562 "Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria" XP_011193901.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011191116.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_011182086.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_028896741.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_011190438.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_011185316.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011185554.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011181724.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_028897057.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011192056.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"RUNX3 regulates WNT signaling" XP_011193418.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_028899267.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_011193963.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_028895248.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_011179324.1 6 Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16 "Circadian Clock";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation" XP_011179881.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" YP_004891167.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_011194910.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_028897908.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028897784.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_011177219.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_028899485.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011187776.1 13 Reactome: R-HSA-202433;Reactome: R-HSA-1855204;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11 "Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system" XP_011182933.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897 "RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes" XP_028895369.1 11 Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-5685938 "Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)" XP_011186316.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_011195575.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011189821.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011188861.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011182740.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011189311.1 6 KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433 "Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_011178129.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_011189124.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_011195430.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011190028.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_011177789.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011197113.1 11 MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055 "Plasmalogen biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_028901918.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555 "Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events" XP_028899273.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_028896939.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011191419.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028896062.1 40 Reactome: R-HSA-5617472;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-75955 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation" XP_011184998.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011185217.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_011179695.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011192182.1 5 MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781 "Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)" XP_011191312.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_011184330.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-9609736;Reactome: R-HSA-3000170;MetaCyc: PWY-7221;Reactome: R-HSA-6794361;Reactome: R-HSA-212676;KEGG: 00230+2.7.4.8 "Nephrin family interactions";"Assembly and cell surface presentation of NMDA receptors";"Syndecan interactions";"Guanosine ribonucleotides de novo biosynthesis";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Purine metabolism" XP_028896805.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_011176467.1 5 KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661 "Propanoate metabolism";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation" XP_028896648.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_011185583.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_011196632.1 3 MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_011182101.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_028898444.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_028899761.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_011186638.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_028899964.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_011187380.1 10 MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms" XP_028901154.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011179914.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-879415 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling" XP_011185649.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_011179554.1 10 KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096 "Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"HS-GAG degradation" XP_028894561.1 20 MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6920 "Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)" XP_011181587.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_011196037.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_011177272.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_011195857.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_011195239.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011190605.1 4 Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism" XP_011182551.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011192164.1 3 KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"Glycine degradation";"One carbon pool by folate" XP_011197131.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011183596.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_011187975.1 4 MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_011187427.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_011187662.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination" XP_011181712.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122 "Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_011179230.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011187517.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-6807505;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation" XP_011193142.1 8 KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "Glycerophospholipid metabolism";"Synthesis of PG";"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_028901117.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011188050.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_011196798.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_028896717.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011185861.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-201722;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"UCH proteinases" XP_011181296.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_028895576.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011189866.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028896774.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_028895200.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_011196429.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_011184851.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_011179916.1 14 KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622 "One carbon pool by folate";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate transformations II (plants)";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)" XP_011189597.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_028899300.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011196882.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_011196914.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_011183936.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_011179370.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_011194886.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_011188067.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_028898440.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_011186563.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_028896064.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_011179106.1 12 MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-1187;MetaCyc: PWY-7901;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6936;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309 "Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_028897953.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_011178987.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_028895705.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_011195263.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_011194033.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_028896855.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_011190011.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_028901382.1 12 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_011179123.1 10 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_028894623.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_011191501.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011189112.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011191689.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Hedgehog 'off' state" XP_028898527.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_028899559.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011186851.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_011177091.1 7 MetaCyc: PWY-6352;MetaCyc: PWY-7625;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11 "3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_028900006.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011178004.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_028898777.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028894736.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011191628.1 30 Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-2564830;Reactome: R-HSA-72086;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Cytosolic iron-sulfur cluster assembly";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_011179760.1 24 Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-5218920;Reactome: R-HSA-5218921;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5625740;Reactome: R-HSA-1257604;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-392451 "CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"FCERI mediated NF-kB activation";"VEGFR2 mediated vascular permeability";"VEGFR2 mediated cell proliferation";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"RHO GTPases activate PKNs";"PIP3 activates AKT signaling";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"G beta:gamma signalling through PI3Kgamma" XP_011182673.1 3 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_011184798.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011178147.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_028898259.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_028896533.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011193318.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011194896.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_011196003.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_028898720.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_011190916.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_011181721.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_011191786.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_028899606.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604 "VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling" XP_028896713.1 4 KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931 "Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_011178578.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011179866.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_011187030.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_028894566.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011176910.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011179476.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011180283.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_028897643.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011176497.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_028897072.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011178236.1 7 Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-5674400 "Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer" XP_011190377.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011189212.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193009.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_011196870.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway" XP_011187100.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_011186431.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_028897797.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_011197056.1 14 KEGG: 00564+2.3.1.15;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.42;Reactome: R-HSA-75896;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453 "Glycerophospholipid metabolism";"Peroxisomal protein import";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis" XP_011183299.1 24 Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-4086398 "ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Ca2+ pathway" XP_011187216.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011184737.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_028894756.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569 "TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_028895301.1 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_028901624.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes" XP_028900473.1 20 MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-735 "10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis" XP_028896333.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011187407.1 58 Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5689901;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Neddylation";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"G2/M Checkpoints";"Degradation of AXIN";"Neutrophil degranulation";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Metalloprotease DUBs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_011182041.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_028898013.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_011188613.2 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_011191985.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_028896714.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_028896705.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_028896364.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011187861.1 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7416 "Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_011190522.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_011190855.1 4 Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation" XP_011182563.1 6 MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism" XP_011178546.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_011176953.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_011190781.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011179879.2 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_028898605.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_011181054.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_011180754.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011180809.1 7 Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-3561 "Role of phospholipids in phagocytosis";"Synthesis of PA";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PG";"Choline biosynthesis III" XP_011196029.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_011188164.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_011190435.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)" XP_011195172.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011184013.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870 "Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins" XP_011181370.1 8 Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-432040 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_011184339.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_028896330.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011192437.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_011195333.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803 "Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing" XP_011186019.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Anchoring fibril formation" XP_011182670.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011189843.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_028899527.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_011187780.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_028901151.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028895599.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_011187953.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011186976.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_011179637.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_028893583.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011182735.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011177922.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_011184337.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011177784.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011176424.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011189674.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_028897013.1 11 Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;Reactome: R-HSA-6804756 "Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation" XP_028897124.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011185157.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_011179664.1 3 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification" XP_028899883.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011191093.1 1 MetaCyc: PWY-6938 "NADH repair" XP_011189765.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_028899491.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_028899557.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011196529.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011188264.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_011190782.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_028901514.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782 "Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis" XP_011179531.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_011186367.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_011176604.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_011187022.1 27 Reactome: R-HSA-111367;Reactome: R-HSA-975956;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-73856;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159227;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-159230;Reactome: R-HSA-975957;Reactome: R-HSA-6803529;Reactome: R-HSA-77595;Reactome: R-HSA-6807505 "SLBP independent Processing of Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Formation of the Early Elongation Complex";"mRNA Capping";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of the SLBP independent Mature mRNA";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"FGFR2 alternative splicing";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes" XP_028899152.1 17 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-75035;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1433557;Reactome: R-HSA-69601;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Transcriptional Regulation by E2F6";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Thermogenesis";"Activation of ATR in response to replication stress";"Signaling by SCF-KIT";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_011187779.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_011193320.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011185832.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011183183.1 4 KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism" XP_011178107.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011180718.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028894200.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011192632.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899545.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028893611.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_028902134.1 13 Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-5689877;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895 "Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Protein methylation";"Ovarian tumor domain proteases";"Josephin domain DUBs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Aggrephagy";"Neutrophil degranulation";"HSF1 activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis" XP_011191776.1 8 MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6611 "Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage V" XP_011191542.1 3 Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism" XP_011192624.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_011190046.1 17 Reactome: R-HSA-75035;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-1433557 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Signaling by SCF-KIT" XP_028897051.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011179194.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_011189087.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569 "TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_011179415.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_011181702.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_028898929.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_028894141.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011194288.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011181029.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025 "Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"EML4 and NUDC in mitotic spindle formation" XP_011188798.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011188816.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_011195573.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011194934.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555 "MET receptor recycling";"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1" XP_011189835.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_011176840.2 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_028898639.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011192997.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011192501.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011180965.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011194113.1 26 Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657 "Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes" XP_011194015.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_028894008.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_028897406.1 3 Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_011177840.1 10 Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-983231 "SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production" XP_011178151.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_011190849.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_011192389.1 83 Reactome: R-HSA-6807004;Reactome: R-HSA-2871796;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-5655291;Reactome: R-HSA-8856828;Reactome: R-HSA-9027284;Reactome: R-HSA-512988;Reactome: R-HSA-1250347;Reactome: R-HSA-5654727;Reactome: R-HSA-9607240;Reactome: R-HSA-8856825;Reactome: R-HSA-5654689;Reactome: R-HSA-180336;Reactome: R-HSA-983695;Reactome: R-HSA-1963640;Reactome: R-HSA-912526;Reactome: R-HSA-8853338;Reactome: R-HSA-1236382;Reactome: R-HSA-8875656;Reactome: R-HSA-375165;Reactome: R-HSA-5654712;Reactome: R-HSA-6811558;Reactome: R-HSA-5637810;Reactome: R-HSA-1250196;Reactome: R-HSA-9645135;Reactome: R-HSA-5654699;Reactome: R-HSA-8851907;Reactome: R-HSA-388841;Reactome: R-HSA-2871809;Reactome: R-HSA-5654688;Reactome: R-HSA-180292;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-9028335;Reactome: R-HSA-5654693;Reactome: R-HSA-5654719;Reactome: R-HSA-9034864;Reactome: R-HSA-1295596;Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-109704;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-74751;Reactome: R-HSA-8983432;Reactome: R-HSA-167044;Reactome: R-HSA-1257604;Reactome: R-HSA-5655302;Reactome: R-HSA-391160;Reactome: R-HSA-5654732;Reactome: R-HSA-5654704;Reactome: R-HSA-210993;Reactome: R-HSA-2179392;Reactome: R-HSA-182971;Reactome: R-HSA-5654700;Reactome: R-HSA-5654726;Reactome: R-HSA-2029482;Reactome: R-HSA-2424491;Reactome: R-HSA-9634285;Reactome: R-HSA-2428933;Reactome: R-HSA-5654695;Reactome: R-HSA-8851805;Reactome: R-HSA-5654706;Reactome: R-HSA-389359;Reactome: R-HSA-1433559;Reactome: R-HSA-5654710;Reactome: R-HSA-112412;Reactome: R-HSA-9028731;Reactome: R-HSA-5654720;Reactome: R-HSA-5673001;Reactome: R-HSA-1839117;Reactome: R-HSA-2730905;Reactome: R-HSA-74749;Reactome: R-HSA-9026519;Reactome: R-HSA-8875360;Reactome: R-HSA-8865999;Reactome: R-HSA-2219530;Reactome: R-HSA-8853334;Reactome: R-HSA-5654733;Reactome: R-HSA-5655253;Reactome: R-HSA-5663213;Reactome: R-HSA-8875555 "Negative regulation of MET activity";"FCERI mediated MAPK activation";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Signaling by FGFR4 in disease";"Clathrin-mediated endocytosis";"Erythropoietin activates RAS";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB4 signaling";"Negative regulation of FGFR2 signaling";"FLT3 Signaling";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR1";"SHC1 events in EGFR signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"GRB2 events in ERBB2 signaling";"Interleukin receptor SHC signaling";"Signaling by FGFR3 point mutants in cancer";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"MET receptor recycling";"NCAM signaling for neurite out-growth";"FRS-mediated FGFR4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by EGFRvIII";"SHC1 events in ERBB2 signaling";"STAT5 Activation";"SHC-mediated cascade:FGFR2";"MET activates PI3K/AKT signaling";"Costimulation by the CD28 family";"FCERI mediated Ca+2 mobilization";"SHC-mediated cascade:FGFR1";"GAB1 signalosome";"RET signaling";"Signaling by SCF-KIT";"Activated NTRK2 signals through PI3K";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR4";"Activated NTRK3 signals through RAS";"Spry regulation of FGF signaling";"Regulation of signaling by CBL";"Downstream signal transduction";"PI3K Cascade";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Insulin receptor signalling cascade";"Interleukin-15 signaling";"Signalling to RAS";"PIP3 activates AKT signaling";"Signaling by FGFR1 in disease";"Signal regulatory protein family interactions";"Negative regulation of FGFR3 signaling";"SHC-mediated cascade:FGFR3";"Tie2 Signaling";"EGFR Transactivation by Gastrin";"EGFR downregulation";"FRS-mediated FGFR2 signaling";"Negative regulation of FGFR1 signaling";"Regulation of actin dynamics for phagocytic cup formation";"DAP12 signaling";"Constitutive Signaling by Overexpressed ERBB2";"SHC-related events triggered by IGF1R";"PI-3K cascade:FGFR2";"MET activates RAS signaling";"FRS-mediated FGFR3 signaling";"CD28 dependent Vav1 pathway";"Regulation of KIT signaling";"PI-3K cascade:FGFR3";"SOS-mediated signalling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR4";"RAF/MAP kinase cascade";"Signaling by cytosolic FGFR1 fusion mutants";"Role of LAT2/NTAL/LAB on calcium mobilization";"Signal attenuation";"Activated NTRK2 signals through RAS";"InlB-mediated entry of Listeria monocytogenes into host cell";"MET activates PTPN11";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by FGFR3 fusions in cancer";"Negative regulation of FGFR4 signaling";"Signaling by FGFR2 in disease";"RHO GTPases Activate WASPs and WAVEs";"MET activates RAP1 and RAC1" XP_028895068.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011176876.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028901423.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_028895755.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_011188503.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_011184358.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_028901081.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011176547.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028902127.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011182060.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_028894602.1 5 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_011193591.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011196879.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168271 "Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus" XP_011189069.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011177689.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_011179609.1 17 Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-174411 "Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere" XP_011180934.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_011180057.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_011180004.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_028896292.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_011186388.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_028894626.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276 "Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_011180745.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_028897194.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_028894166.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_011195453.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899960.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_011190996.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_011180253.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_011192612.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011182336.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_028898021.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011191896.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011190887.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011195803.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_028895771.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011182366.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_028899544.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011194067.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028899911.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_011179849.1 10 MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864 "Urate conversion to allantoin I";"Retinoid metabolism and transport";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Purine metabolism";"Retinoid cycle disease events" XP_011185619.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011190608.1 4 KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558 "Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine" XP_028895821.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_011184385.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_011185576.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_011187677.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011180006.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186280.1 15 Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-9664565;Reactome: R-HSA-9665246;Reactome: R-HSA-9665250;Reactome: R-HSA-9665251;Reactome: R-HSA-9665245;Reactome: R-HSA-5637810;Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-9634285;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282 "Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Overexpressed ERBB2";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling" XP_028898435.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_028899725.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_011185511.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_028900163.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_011195759.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_011178365.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011192996.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011179617.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_028901144.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_011184517.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_028902123.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_028898793.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_028898878.1 6 KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122 "Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis" XP_011181867.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"ESR-mediated signaling" XP_011182159.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_011182697.1 18 MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5913;MetaCyc: PWY-6638 "(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III" XP_028897916.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_028896328.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011181714.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011196428.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_011179862.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028899904.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_028900154.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958 "Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_011196550.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_011186896.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_011176659.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_011178494.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011182814.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_011196215.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_028898869.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_011192273.1 4 KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I" XP_011193958.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_028899769.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition" XP_028895172.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_011179762.1 24 Reactome: R-HSA-5607764;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;Reactome: R-HSA-2871837;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;Reactome: R-HSA-392451;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740 "CLEC7A (Dectin-1) signaling";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"FCERI mediated NF-kB activation";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Downstream TCR signaling";"Activation of AKT2";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs" XP_011188618.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011183700.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_028898640.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011191143.2 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_028896073.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_028895274.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011192723.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011190847.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_028896899.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011187557.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_011177387.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028900458.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_011178411.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_011178261.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_028898710.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_011178596.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011178012.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_011176507.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148 "Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011197139.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_028895897.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_011189123.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_011195960.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011178133.1 4 MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_011191365.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_028898265.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011192633.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178288.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle" XP_028899726.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_011184093.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011193213.1 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131 "Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_028895758.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_011192915.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_011193648.1 56 Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113 "Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Neddylation";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1" XP_011196970.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011184903.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_011188436.1 17 Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_011189494.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_011180961.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011186581.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_011185971.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_011195565.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_011193587.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_011185991.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011182901.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011188283.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_028895953.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011177939.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011192401.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_028897501.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_011192550.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_028896875.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_011196094.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_011195473.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_028899835.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_011196268.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011184414.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_028899292.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_011191686.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_028901830.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_011178409.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase" XP_028895367.1 11 Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-8939236 "Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_011189551.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling" XP_011180829.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011185776.1 12 MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5856;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-5855 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_011187401.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_028893695.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_028899518.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_028896942.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028900992.1 26 Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production" XP_011194405.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028896754.1 8 Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Activation of RAC1";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_028895521.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011188145.1 7 MetaCyc: PWY-7234;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_011188349.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_011188292.1 30 Reactome: R-HSA-8941332;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8948751;Reactome: R-HSA-392451;Reactome: R-HSA-9634638;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-8876198;Reactome: R-HSA-111447;Reactome: R-HSA-389513;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-199418;Reactome: R-HSA-198323;Reactome: R-HSA-6804758;Reactome: R-HSA-6804759;Reactome: R-HSA-389357;Reactome: R-HSA-9614399;Reactome: R-HSA-5218920;Reactome: R-HSA-69202 "RUNX2 regulates genes involved in cell migration";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN stability and activity";"G beta:gamma signalling through PI3Kgamma";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"RAB GEFs exchange GTP for GDP on RABs";"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"AKT phosphorylates targets in the nucleus";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the cytosol";"Regulation of TP53 Activity through Acetylation";"Regulation of TP53 Activity through Association with Co-factors";"CD28 dependent PI3K/Akt signaling";"Regulation of localization of FOXO transcription factors";"VEGFR2 mediated vascular permeability";"Cyclin E associated events during G1/S transition" XP_028899834.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_028901635.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011186672.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193056.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028896277.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028895364.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011188848.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011188376.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_011196059.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782 "Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis" XP_028899775.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_028895914.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011179421.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_028901804.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028900692.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_028899705.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011178508.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network" XP_011182743.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028894629.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168 "Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028894412.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_028899375.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_028902228.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_011180195.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_011177927.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_011188378.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_011187336.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_028900246.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_011196909.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011185089.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_028897314.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_011178310.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_028901977.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011177903.1 17 Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-674695;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery" XP_011181127.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028899572.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028893633.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_028899972.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"RUNX3 regulates WNT signaling" XP_011187948.1 8 Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-71336;Reactome: R-HSA-5659996 "RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P" XP_011189025.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_011181508.1 6 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination" XP_028896902.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028901883.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011188336.1 37 Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-9639288;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-983170;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-204005;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-2132295;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"snRNP Assembly";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Viral Messenger RNA Synthesis";"HCMV Early Events";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"COPII-mediated vesicle transport";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"MHC class II antigen presentation";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011185823.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657 "NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes" XP_011186010.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_011188865.1 11 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-383280;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Generic Transcription Pathway";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_011190184.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011192799.1 57 Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-350562 "Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Neddylation";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)" XP_028897058.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028896036.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade" XP_011180409.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011193322.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011181481.1 6 Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781 "Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"PPARA activates gene expression" XP_011190724.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_028900842.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_028901717.1 7 KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020 "Photosynthesis";"Cristae formation";"ATP biosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import" XP_011191811.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_011190449.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011180322.1 7 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-5685938 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)" XP_011193949.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_011196883.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_028900562.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_011193780.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186000.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_028898679.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011185836.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011176602.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_011187800.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_011196703.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_011189082.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_011185465.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_028899852.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_028902226.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_011182936.1 10 MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-1042 "Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Galactose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)" XP_011186596.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_011197005.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_011181675.1 6 MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_011187545.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011180179.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_028899266.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_028897031.1 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_011187616.1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-174154 "Defective CFTR causes cystic fibrosis";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin" XP_011192803.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055 "Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis" XP_011195487.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011185560.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_028896346.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011180636.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011193269.2 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_011186869.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_028896355.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011178279.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_011195002.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_011192187.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_028893843.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_011188267.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_011179509.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011195006.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_011185688.1 9 Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69205 "Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"G1/S-Specific Transcription" XP_011194222.1 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255 "UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis" XP_028901376.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975957 "mTORC1-mediated signalling";"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_028897821.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193390.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_028900403.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011182561.1 6 MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11 "Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism" XP_028894122.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028901063.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_028899767.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_011177658.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011192593.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" XP_011190225.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_011195556.1 17 MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6627;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-6644;Reactome: R-HSA-6798695 "Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine salvage";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Purine metabolism";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation" XP_011179836.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism" XP_011195818.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011176837.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011191310.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028900298.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_011181619.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028900544.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_011187559.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011183399.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_011184568.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_011186888.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_011184780.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028899819.1 8 MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6611 "Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage V" XP_011195921.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_011181663.1 17 Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-937042 "IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex" XP_011181800.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011181028.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025 "Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"EML4 and NUDC in mitotic spindle formation" XP_028896430.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011177798.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_011190425.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011196365.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_011182496.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_028901026.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_011183726.1 7 Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16 "Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_011196441.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011187641.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011186371.1 16 Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-674695;Reactome: R-HSA-8951664 "RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Pre-transcription Events";"Neddylation" XP_011177571.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011194301.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation" XP_011194877.1 6 KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" XP_011190111.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_011184054.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_028894505.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_011187679.1 15 Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174048 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_028897151.1 7 Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane" XP_011189076.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_011179139.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011194567.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011194080.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_028897014.1 3 MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96 "L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis" XP_011188250.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011187896.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_011177993.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" XP_011190263.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028899229.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011190053.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_011191634.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-3878781 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)" XP_028901934.1 12 Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9 "Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Glycogen synthesis";"Glycerolipid metabolism" XP_011196330.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6361;Reactome: R-HSA-1855167 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol" XP_011186555.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_011193513.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_011179129.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_011192258.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_011196943.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_028897201.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011179412.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_011187050.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_028896195.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_011181208.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011179856.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_028900864.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011182915.1 14 MetaCyc: PWY-8052;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4 "2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PE";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism" XP_011192300.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_011187771.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186920.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_011185665.1 4 Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030 "Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis" XP_011187000.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011185371.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_028900996.1 26 Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-9614657 "Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes" XP_028901626.1 16 Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884 "Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX" XP_028895941.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011193227.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_011185233.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_011177937.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011196436.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_011195418.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011182980.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-428930 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor" XP_028900525.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028901045.1 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255 "UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis" XP_011180160.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011195021.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_028901616.1 4 KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221 "Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis" XP_011187255.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011182911.1 14 MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4 "Plasmalogen biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PC";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism" XP_011182149.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_028900803.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-5578775 "RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis" XP_011193323.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011191087.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011181611.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_011196678.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_011194184.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011179559.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_028900216.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_011189985.1 23 Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-432040 "Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_028902230.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_011196926.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011195330.1 11 KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-882;MetaCyc: PWY-3881;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-5659 "Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"GDP-mannose biosynthesis" XP_028897326.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_011179107.1 12 KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-801;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-1187;MetaCyc: PWY-7901 "Selenocompound metabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine" XP_011177720.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_011196421.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73762 "RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation" XP_011176779.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011194989.1 7 Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7841 "Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Neolacto-series glycosphingolipids biosynthesis" XP_011181375.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_011179838.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism" XP_011184466.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_011178161.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_028900244.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011195371.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_011190319.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_011176975.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011187897.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_011191935.1 13 KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545 "Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_011182045.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_011185201.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_011181026.1 22 Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-195253 "APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex" XP_028894843.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_011193006.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_011182734.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-1236978 "ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_028897278.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011176902.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011181205.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_028900257.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011189172.1 28 Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-5693607 "Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Meiotic recombination";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends" XP_028896208.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028896676.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_011182244.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011194365.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_011194965.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011197014.1 6 Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;MetaCyc: PWY-7382;MetaCyc: PWY-6987 "Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_011192592.1 13 MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916 "Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation" XP_011183873.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_011180296.1 5 Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94 "Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_011178111.1 4 MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_011194546.1 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_028894787.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692 "MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity" XP_011176978.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_028894145.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_028894006.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_011193314.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011178556.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_011182043.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_028901211.1 9 MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-7411 "Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)" XP_028897913.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_011179219.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011193729.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011180814.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_011188624.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028897389.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_028899490.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_011186348.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011187887.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_028895966.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation" XP_011183589.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028894426.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_028897150.1 7 MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system" XP_011195448.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432722 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis" XP_028900802.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692 "Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity" XP_011179163.1 57 Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764 "UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Neutrophil degranulation";"Degradation of AXIN";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling" XP_011186478.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism" XP_028895752.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_028900535.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028899462.1 19 KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;Reactome: R-HSA-75105;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;MetaCyc: PWY-7384;Reactome: R-HSA-163765;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5538 "C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI" XP_011177245.1 5 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"EPHB-mediated forward signaling" XP_011182832.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_028900787.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA" XP_011179524.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_028902170.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011184409.1 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606 "TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_011184811.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181306.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-167246 "Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript" XP_011177485.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_011178401.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_011191076.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_028895881.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_028896225.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_011183702.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_028895810.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408 "SUMOylation of DNA damage response and repair proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"HCMV Early Events";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"snRNP Assembly";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism" XP_028899961.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_028900615.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_028899848.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011183195.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011195432.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028897311.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_028900067.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-917729 "Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_028896348.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_028899372.1 17 MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5744 "Candicidin biosynthesis";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation" XP_028899493.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_028901841.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_011192880.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_011196085.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_011177910.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_011187556.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011178287.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Nitrogen metabolism";"Reversible hydration of carbon dioxide" XP_011183882.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028896070.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_011186025.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_011182466.1 6 MetaCyc: PWY-7356;MetaCyc: PWY-6908;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-6898 "Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III" XP_028895882.1 3 Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation" XP_011188549.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011176655.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_028900592.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028894419.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_011191077.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_028897697.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_028895871.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_011195205.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011193904.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_011179226.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028895275.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028901470.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_028897695.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_028899108.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011182073.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_028897498.1 7 Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Ub-specific processing proteases";"UCH proteinases";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex" XP_011192826.1 6 KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6317 "Galactose metabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)" XP_028900613.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011187548.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_011184012.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702 "SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling" XP_011186080.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_011177379.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181268.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028895054.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028896874.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_028897580.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011192113.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_028899230.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028898217.1 30 Reactome: R-HSA-5610780;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-2565942;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2644607;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-69231 "Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition";"Prolactin receptor signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cyclin D associated events in G1" XP_028897536.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_028899150.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_011189626.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Activation of RAC1";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_028896285.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011192591.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" XP_028894214.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028901625.1 16 Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519 "Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression" XP_011195882.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028895613.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028900269.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011190652.1 17 MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Candicidin biosynthesis";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes" XP_028900213.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_011188266.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_011194450.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_011185609.1 10 Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011177425.1 9 Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097 "FCERI mediated MAPK activation";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway" XP_011189750.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events" XP_011193836.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_028901426.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_011195858.1 4 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_011196700.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011194267.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" XP_028898479.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_028899138.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_028893834.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921 "Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation" XP_011182966.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_011193942.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism" XP_011196218.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378 "Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling" XP_011189466.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-6799198 "Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis" XP_028894823.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_028896901.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011190748.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_028900749.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_011195091.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_011192701.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_011176511.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_011188823.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_011185947.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_028898212.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_011182046.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_011196884.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_011190039.2 16 KEGG: 00680+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1622 "Methane metabolism";"Glycolysis";"Rubisco shunt";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)" XP_011188158.1 4 KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Glycerol degradation I" XP_011189655.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_028894203.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011190888.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028899186.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011191556.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_028894312.1 10 Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-983231 "Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production" XP_011176708.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_028901353.1 8 KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Starch and sucrose metabolism" XP_011182584.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_028894255.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_028897754.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_028898029.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_028894737.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011182681.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_011178467.1 5 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation" XP_011182842.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_028899999.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_028900027.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_011183410.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011196908.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011181140.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011181516.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028896765.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011187275.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011181069.1 7 Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5635838 "HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Activation of SMO" XP_011180087.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011184150.1 11 Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518 "COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2" XP_011187007.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_011184684.1 5 Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630221 "Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing" XP_011188195.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_011178435.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409 "APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A" XP_028894408.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_028894733.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011185573.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028896693.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_011179576.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_011179860.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028898751.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700 "MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_011191117.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_011190790.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_011186784.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_011193218.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" XP_028898409.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011180743.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011185359.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_028894164.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" XP_011184621.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011179979.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011186224.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_011179696.1 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_011184230.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_011181145.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_011179857.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011184509.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_011191185.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028894196.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028896938.1 7 MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204 "3-phosphoinositide degradation";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol" XP_011194654.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_011194535.1 8 Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Signaling by Hippo";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_011195624.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011177892.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_028895225.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011180979.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_011177899.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_011197143.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_028897244.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011185218.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_011180167.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_011182934.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_028895665.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-442720 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_011180258.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_011191047.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_028899768.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_028897827.1 6 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6922 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis" XP_028893647.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358751 "RAF activation";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated" XP_028897589.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_028898258.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_011180321.1 12 Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_011184860.1 5 MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-7863;Reactome: R-HSA-196843 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism" XP_028901903.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028901680.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028894248.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011180546.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_028896399.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011191422.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011176777.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011185076.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011195171.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_011194550.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_028901468.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_011192357.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_028899492.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_011187602.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_011180146.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_011178116.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_011189063.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_011196686.1 13 MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-7410 "(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis" XP_028896283.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011187067.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_011194402.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_011196270.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011180582.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_028897960.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011180428.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011185621.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011190297.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011190636.1 5 Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "Regulation of PTEN stability and activity";"Protein ubiquitination";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_011180136.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_028902241.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_011186903.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_028893548.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_028898482.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_028899826.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_011186298.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_011177098.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_011194235.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_011181776.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_011191983.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011195310.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_011191908.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028895888.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_011183672.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation" XP_011182595.1 42 Reactome: R-HSA-3214847;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-3214815;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-977225;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-69473;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-2299718;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-427413 "HATs acetylate histones";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Amyloid fiber formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Condensation of Prophase Chromosomes";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NoRC negatively regulates rRNA expression" XP_028898049.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028898976.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_028898833.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011182476.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_028894158.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_011179071.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_028894931.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916 "MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation" XP_011196395.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_011177811.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_011187786.1 7 KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_011189401.2 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_011187888.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_011190127.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_028900031.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011190713.1 57 Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870 "Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins" XP_011192751.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_011189343.1 14 Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788 "Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling" XP_028893641.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011179816.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011187206.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028900646.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_011180495.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8875656 "RAB geranylgeranylation";"MET receptor recycling" XP_011189528.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_028895587.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_028898684.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011189230.1 10 MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842 "Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II" XP_011192845.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_011188544.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_011192890.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011189186.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_011184650.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_011177244.1 5 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"EPHB-mediated forward signaling" XP_011183993.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation" XP_011184765.1 4 MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" XP_028893696.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_028902225.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_011191279.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028900523.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011178768.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_028901735.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011183777.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011191273.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011182288.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis" XP_011196512.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_028896846.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_028896289.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011183591.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011185189.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_028899549.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_011178092.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011194858.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport" XP_011177104.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028895053.1 8 KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_011177491.1 11 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Relaxin signaling pathway" XP_011190095.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" XP_028893648.1 22 Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558 "Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011196378.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_011179137.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028896063.1 14 Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-6798695;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948 "EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Neutrophil degranulation";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_011192183.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011196952.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011194707.1 17 Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-8853884;Reactome: R-HSA-983168 "APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011189326.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_011184060.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_011188842.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011189313.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028897242.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011178983.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_028898157.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_028896045.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011184603.1 10 Reactome: R-HSA-3214847;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "HATs acetylate histones";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Ub-specific processing proteases";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_011186261.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_011196671.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011188423.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_011195023.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_011194399.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011192017.2 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_028898668.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_011176548.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028898211.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_028893644.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558 "Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011192332.1 7 Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2 "Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis" XP_011177196.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_028901787.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011193579.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_028896074.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_011177801.1 6 MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484 "Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_011183294.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011191354.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_028896775.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_011195975.1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_028893546.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_011176778.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011188883.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028897121.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011177997.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011187663.1 3 Reactome: R-HSA-6807505;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011194182.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_011178280.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_011197155.1 5 MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6 "UTP and CTP dephosphorylation I";"Purine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism" XP_011182582.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011180229.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_028896708.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_028896575.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028897603.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_028894198.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011177812.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_011177747.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_011186346.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_011181990.1 18 MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7176 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis" XP_011186031.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_011178407.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase" XP_011180988.1 6 MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Vitamin B6 metabolism";"Serine biosynthesis";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism" XP_028900751.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_011183355.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028898446.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_028897200.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028899778.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_028894119.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs" XP_028899347.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028894747.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_028900719.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_028895622.1 16 Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-1251985;Reactome: R-HSA-1250342;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558 "GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"Nuclear signaling by ERBB4";"PI3K events in ERBB4 signaling";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011187769.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028900502.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo" XP_011188020.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028893829.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028895266.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011183387.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346 "GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis" XP_011181578.2 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_011181790.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210 "G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_011178521.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_011177342.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028898529.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_011176471.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558 "Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_011191406.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011178663.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_028899310.1 7 MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25 "Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_028901064.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011178581.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011186984.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011183610.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695 "Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_011190236.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_028895913.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011178998.1 4 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782315 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol" XP_011187338.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_028898840.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011191299.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_028902011.1 6 MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_011196078.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade" XP_011179149.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_028896329.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011184198.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-4661;MetaCyc: PWY-6664 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis" XP_011190387.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028895514.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028894608.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011196198.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_011180256.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_028899763.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_011185549.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_028895196.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011184715.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_011183678.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_028897641.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011191819.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_011190951.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_011187451.1 5 Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787 "BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog 'off' state" XP_028896071.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_011193950.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism" XP_011184044.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_011179638.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_011192064.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011193357.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_028901849.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_011183406.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_028900239.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_028893626.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_028899636.1 3 Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-383280 "AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"Nuclear Receptor transcription pathway" XP_011178575.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_028893606.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011182557.1 6 MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11 "Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism" XP_011196400.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_011182414.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_011192933.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_028901803.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011189020.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_011188973.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011179144.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011188831.1 14 MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-7409 "Anandamide biosynthesis II";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_028901005.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;MetaCyc: PWY-7511 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination" XP_011193689.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_028894118.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_011190330.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_011195917.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_011189809.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803 "Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing" XP_028901000.1 26 Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-933541 "NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation" XP_011189460.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_028900096.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_028898525.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_011182929.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011195767.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_011183975.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits" XP_028899772.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_011191953.1 3 MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3 "Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism" XP_011194937.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555 "MET receptor recycling";"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1" XP_011183233.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028900828.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011180204.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_028900249.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011190156.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_028900260.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011191002.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_028896368.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011193228.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_011182783.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_011197009.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_028900070.1 5 MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_011187106.1 11 Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_028900151.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361 "Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_011181184.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_011187685.1 1 Reactome: R-HSA-419771 "Opsins" XP_011187547.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_028898781.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_011193798.1 5 Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events" XP_011187635.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011182542.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028894220.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011188533.1 33 Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"snRNP Assembly";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"RHO GTPases Activate Formins" XP_028894619.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_011194589.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141 "Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism" XP_011180506.1 12 MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70263;MetaCyc: PWY-1042 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)" XP_028894938.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011193592.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011188347.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_011195916.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_028895104.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028894328.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_011179341.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894179.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)" XP_028898483.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_028897497.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_011192195.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011178268.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_011194193.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011179223.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028897988.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_028899908.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_011187460.1 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" XP_011185725.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_011187382.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028896278.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011191930.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_028900452.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011183950.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011180968.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_011189868.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011176951.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011196709.1 8 Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-380972 "Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_028893671.1 13 Reactome: R-HSA-6802955;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants" XP_011186253.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_011180746.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011187374.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011180354.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_028894222.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011195454.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011180038.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193927.1 5 Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383 "Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_011194230.1 6 Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_011194712.1 4 MetaCyc: PWY-7887;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12 "Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_011176675.1 8 KEGG: 00220+4.3.2.1;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-7400;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-5154 "Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)" XP_011190140.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011193351.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_011178541.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028894912.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_011190123.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028895574.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011181207.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation" XP_011191082.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_028899403.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011186831.1 8 Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2 "Catecholamine biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis" XP_028894739.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011177034.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_011190076.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_011192902.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_011177482.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300 "Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_011184342.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_011194723.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_028896937.1 7 Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_011188872.1 6 Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391 "Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)" XP_028897068.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028895363.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011192241.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011190574.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028895244.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011181952.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011187620.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins" XP_011195571.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_011191701.2 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_028895252.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028900897.1 3 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_011196289.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_011195071.1 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011177479.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_011189780.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011186776.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011192702.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_011194155.2 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_011194331.1 58 Reactome: R-HSA-77288;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00281+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-6945;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17;Reactome: R-HSA-77348;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77285;MetaCyc: PWY-1361;KEGG: 00627+4.2.1.17;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7606;MetaCyc: PWY-6946;MetaCyc: PWY-5789;Reactome: R-HSA-77350;Reactome: R-HSA-77310;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7656;Reactome: R-HSA-1482798;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;Reactome: R-HSA-77305;MetaCyc: PWY-7216;MetaCyc: PWY-6944;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;Reactome: R-HSA-77346;KEGG: 00623+1.1.1.35 "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Geraniol degradation";"Fatty acid elongation";"Glutaryl-coa degradation";"Fatty acid salvage";"Butanoate metabolism";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"Caprolactam degradation";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Lysine degradation";"2-methylpropene degradation";"Fatty acid elongation";"Tryptophan metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Propanoate metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Benzoate degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Benzoyl-coa degradation I (aerobic)";"Aminobenzoate degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Carbon fixation pathways in prokaryotes";"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"Acyl chain remodeling of CL";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Toluene degradation" XP_028896163.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_028900214.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_011192210.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011177979.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178197.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_028898470.1 5 MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_011190205.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011178149.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028900534.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_011183437.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_028899484.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011187988.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_011192697.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_011179082.1 26 Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483 "Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Gap junction assembly";"RHO GTPases Activate Formins";"HCMV Early Events";"Activation of AMPK downstream of NMDARs" XP_011190575.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_011179605.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"RAF/MAP kinase cascade" XP_028893758.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_028900248.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011195940.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_011177528.1 6 KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_011179127.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_011179201.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_011191043.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011178183.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011190322.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011187601.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_028898795.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_011177683.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_028897325.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_011185097.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690 "Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events" XP_011180482.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_028898511.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_011196846.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_028896284.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011195451.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011186755.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_011197045.1 19 MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-5690 "Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Pyruvate metabolism";"Gluconeogenesis";"Methane metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)" XP_011183306.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation";"Collagen degradation" XP_028896207.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_011187767.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Regulation of PTEN localization" XP_028893585.1 9 Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors" XP_011178814.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_011178530.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_028896870.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_028894168.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_011188828.1 14 Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416 "Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_011194389.1 26 Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-6804114;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-8866654;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-1362277;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-4615885;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169 "Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"E3 ubiquitin ligases ubiquitinate target proteins";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"SUMOylation of DNA replication proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis" XP_011188525.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_011192405.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_028900850.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_028896680.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011182667.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_028895845.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230 "Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane" XP_011185816.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_028894471.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_028893726.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011180323.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_028894219.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028901491.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028897461.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011187331.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011196715.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" XP_028895331.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_011193760.1 5 KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_011189184.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_028902052.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011187204.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_028896295.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011178309.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_011187262.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011187978.1 4 MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_028899542.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028900536.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_011189480.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_011188089.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events" XP_011181033.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011187642.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011196878.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_011186482.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_011184331.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_028901573.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_011191099.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011196083.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_011189977.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_011176987.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011188397.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_011194391.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_011183758.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011188421.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011184679.1 18 KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6644;MetaCyc: PWY-6608;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6627;KEGG: 00983+2.4.2.3;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-5532;MetaCyc: PWY-4202 "Purine metabolism";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Pyrimidine catabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)" XP_011178911.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_011184518.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_011180453.2 14 MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_011182871.1 10 MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362 "Sulfite oxidation III";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Purine metabolism";"Transport and synthesis of PAPS" XP_011184967.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" YP_004891170.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_028894952.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_028901884.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_011185489.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_011190369.1 12 KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13 "Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism" XP_028896060.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_028900457.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_028901549.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7838 "Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis" XP_011191270.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_011190197.1 5 KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4 "Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Geraniol degradation";"Mevalonate degradation";"Valine, leucine and isoleucine degradation" XP_011193177.1 8 Reactome: R-HSA-4608870;Reactome: R-HSA-4641263;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398 "Asymmetric localization of PCP proteins";"Regulation of FZD by ubiquitination";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway" XP_011180420.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011181862.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_028900805.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-3371571 "Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"HSF1-dependent transactivation" XP_028895601.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_011192935.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_011183682.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_028894891.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_011186363.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC";"Glycerophospholipid metabolism" XP_028896019.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism" XP_011188203.1 4 Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16 "Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism" XP_028901623.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585 "Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence" XP_011191851.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_028898249.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920 "PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability" XP_028898772.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_011176796.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_028898452.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_011176472.1 22 Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-2467813 "APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids" XP_011178960.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011177659.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_011184714.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II" XP_028894012.1 6 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_011190155.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_028898560.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_011185419.1 33 Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5619107 "RHO GTPases Activate Formins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"snRNP Assembly";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_011188095.1 14 Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416 "Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_011184709.1 3 MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96 "Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis" XP_011179924.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577 "Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21" XP_011182867.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_028900567.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_028897462.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011179221.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011184275.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_028900144.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_011194006.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_028899160.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_028893850.1 9 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol" XP_011179885.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028900491.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011190469.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_028894044.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011186686.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_011195449.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011189270.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_011186035.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_011194771.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_011189731.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011196910.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_028893866.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011186566.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011182533.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_011189462.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011191544.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028896276.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_011191514.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011192625.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs" XP_028895977.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101 "HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation" XP_011191044.1 34 Reactome: R-HSA-69656;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-69202;Reactome: R-HSA-69273;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-8939236;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086 "Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"Cyclin E associated events during G1/S transition";"Cyclin A/B1/B2 associated events during G2/M transition";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping" XP_011187141.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_011194452.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_011186252.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_011192147.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011185617.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011188280.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011182019.1 5 Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling" XP_011196369.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_011179529.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_011180500.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_028896682.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011196934.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011192922.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011189078.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_011192062.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_028899055.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_011177841.1 10 Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9022692 "Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity" XP_028899608.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011184130.1 13 KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206308;Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670 "Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"MPS IV - Morquio syndrome B";"Sialic acid metabolism";"Sphingolipid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis" XP_011193830.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_011184776.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011195450.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011192429.1 22 MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7053;MetaCyc: PWY-7726;MetaCyc: PWY-5353;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_028896077.1 6 MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_011183701.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011196267.1 11 Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001 "PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade" XP_028894562.1 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387 "Oxidative phosphorylation";"Amino acids regulate mTORC1";"ATP biosynthesis";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Photosynthesis";"Insulin receptor recycling" XP_028895258.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011184410.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-1362409 "Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" XP_011183518.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_028897243.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011192534.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_011184512.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_011187084.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-159230 "Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA" XP_011181012.1 7 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-9033241;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Peroxisomal protein import";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_011181814.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011194343.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011193667.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_028896072.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_028896573.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011189459.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_011180457.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028900152.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828 "Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis" XP_011196781.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_011197079.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011193697.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011190629.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_011185938.1 7 Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.15 "Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis" XP_011181137.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028895597.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_011181959.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" XP_011181056.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_028898293.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_011188232.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_011187266.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011190749.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_011192535.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_028894522.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_011194270.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_011196554.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011181851.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011191067.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_011194828.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_011196200.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011177804.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_011190401.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_011183640.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011178706.1 8 KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_011181367.1 8 Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-432040 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_011192700.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011183606.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation" XP_011195228.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011189214.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_028894027.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011190264.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_011186037.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_011196371.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" NP_001291679.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_011180953.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011182377.1 20 Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121 "Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI" XP_011179109.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_011195707.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_011195868.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_011178739.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028898706.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028895228.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_011185622.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_028894728.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-426486 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis" XP_011193793.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_028897529.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_011180493.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028902126.1 13 MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736 "Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis" XP_028897018.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028899299.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011193935.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011192894.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_011189535.2 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_011176756.1 8 KEGG: 00220+6.3.4.5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5;MetaCyc: PWY-4984;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-7400;MetaCyc: PWY-5154 "Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Canavanine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)" XP_011182511.1 5 MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)" XP_011188117.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_011177810.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_028897644.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_011195794.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028898355.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_028897727.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878 "AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport" XP_011182752.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011189366.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_011190741.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex" XP_011178915.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_011179216.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028902236.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_011179550.1 10 Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292 "Hyaluronan uptake and degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"HS-GAG degradation";"MPS VII - Sly syndrome" XP_011183738.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_011188261.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_011188174.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011186382.2 5 Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16 "RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_028900994.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation" XP_011191137.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_028895707.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_011188321.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_011190139.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011196341.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011196944.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_028894966.1 13 KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-7533 "Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis" XP_028898214.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011192686.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_028901758.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028894405.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011194363.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_011193604.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828 "LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"VLDL clearance";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"LDL clearance";"Clathrin-mediated endocytosis" XP_028899892.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_028894649.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_028900063.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_011186481.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_011182142.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011194833.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_011185671.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_028899487.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011180970.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_028901432.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011178661.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Photosynthesis";"Amino acids regulate mTORC1";"ATP biosynthesis";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011176530.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028899707.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011196214.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_028894565.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011192053.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_028895279.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_011196068.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011182926.1 11 Reactome: R-HSA-109704;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-5668599;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;Reactome: R-HSA-1660499;Reactome: R-HSA-168138;Reactome: R-HSA-1660514 "PI3K Cascade";"Macroautophagy";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the plasma membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane" XP_011195776.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011179164.1 57 Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577 "Neutrophil degranulation";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21" XP_028898248.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757 "VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation" XP_011183884.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011181249.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011184226.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-198323 "Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTOR signalling";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol" XP_011186009.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_011184383.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation" XP_011180498.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_011183553.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_028901978.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028896681.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028897534.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_028895245.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_028897323.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_028894086.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_028898031.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis" XP_011194289.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_011178540.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011187833.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_011182370.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011178414.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_011190871.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_011180707.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011176946.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011184393.1 9 MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-5484 "Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)" XP_011186800.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_011177634.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472 "Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011183686.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011180060.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_028897055.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_028898135.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011181593.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011190911.1 5 Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;Reactome: R-HSA-9627069 "Formation of apoptosome";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity" XP_011193020.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_011182074.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane" XP_011180876.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_011191491.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_028896755.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Activation of RAC1" XP_028896574.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_028896959.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_028899742.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_028899714.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_028894247.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011176977.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011179404.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011189202.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis" XP_028898778.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028895370.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_028902048.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028897373.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011194042.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis" XP_028899824.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011184415.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_011188766.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011196394.1 6 KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Rubisco shunt";"Pentose phosphate pathway" XP_011179343.2 13 MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5913 "Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)" XP_011188936.1 14 Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Macroautophagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_011197073.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011190143.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011179691.1 13 MetaCyc: PWY-2261;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370 "Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Ascorbate recycling (cytosolic)" XP_011187259.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028899970.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_011192055.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011184640.1 10 Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856 "Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling" XP_028901807.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011177293.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_011191731.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011186569.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870 "Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins" XP_011195470.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011194508.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-7902 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis" XP_011190424.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_011187273.1 10 Reactome: R-HSA-72702;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"PERK regulates gene expression";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation" XP_011188907.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_028899779.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_011185442.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011191849.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193283.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_028899067.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214 "ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins" XP_028897956.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011190523.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_011188996.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_011197106.1 9 KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation" XP_011184584.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_011181812.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_011184554.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180630.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_028896762.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028901994.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade" XP_028900920.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_011179614.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_028894189.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028896352.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011179530.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis" XP_011190789.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_011195670.1 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III" XP_011178413.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_011181801.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_028896848.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_011189754.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_011185627.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_028902064.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation" XP_011181013.1 7 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9033241;Reactome: R-HSA-72163;Reactome: R-HSA-9010553 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Peroxisomal protein import";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs" XP_011184695.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_011176469.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221 "EML4 and NUDC in mitotic spindle formation";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway" XP_011184616.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_028899765.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_011193623.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_028899451.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_011180476.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_028899774.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_028896059.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_011191691.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568 "Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_028897324.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_011189137.1 15 Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402 "S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex" XP_011188189.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_011187619.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_011178323.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011183603.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_011189546.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_011182008.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_028898175.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_011184454.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011193781.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_028897464.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011176539.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011187252.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028896061.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_028901922.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_011190462.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_028899957.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_028899482.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011188319.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_011196039.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_011178316.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_028895361.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011194540.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_011180907.1 42 MetaCyc: PWY-7606;MetaCyc: PWY-5789;MetaCyc: PWY-6946;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-6583;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00623+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6944;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7779;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7654;MetaCyc: PWY-7401 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Propanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid degradation";"beta-Alanine metabolism";"Aminobenzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to butanol I";"Phenylalanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to hexanol (engineered)";"Toluene degradation";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Methyl tert-butyl ether degradation";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Glutaryl-coa degradation";"Fatty acid elongation";"Fermentation to 2-methylbutanoate";"Caprolactam degradation";"Fatty acid salvage";"Butanoate metabolism";"Limonene and pinene degradation";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Tryptophan metabolism";"2-methylpropene degradation";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)" XP_028897826.1 6 MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_011184936.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011179312.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_011194333.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011185905.2 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_011190788.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702 "SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling" XP_011176529.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011194009.1 4 KEGG: 00513+3.2.1.114;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_011187247.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011185194.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" XP_011190688.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_011187555.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_011179055.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011187176.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_028894087.1 9 Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-114604 "VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade" XP_011179225.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028898438.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011182289.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028900004.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy" XP_011190368.1 12 Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142 "Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_028897795.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Neddylation";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_011192404.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_011193443.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011194370.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011190812.1 34 Reactome: R-HSA-9639288;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749 "Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Separation of Sister Chromatids";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Transcriptional regulation by small RNAs" XP_011178773.1 12 KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13 "Carbon fixation in photosynthetic organisms";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway" XP_011196325.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011181775.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_011182152.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_028895642.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_011183457.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011191994.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_011193515.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011181323.1 16 Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1963640;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-1251985;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001 "Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"GRB2 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade" XP_028898957.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation" XP_011178427.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_011190904.1 19 MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;MetaCyc: PWY-7384;Reactome: R-HSA-75105;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172 "Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)" XP_011190414.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_011188725.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_011187109.2 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_011189444.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011196566.1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949 "G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin" XP_028897958.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_028900177.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011186704.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028896339.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011193123.1 9 KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-7003 "Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol" XP_011177055.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895605.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation" XP_028899351.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011187439.1 13 Reactome: R-HSA-2022090;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244 "Assembly of collagen fibrils and other multimeric structures";"Signaling by PDGF";"Collagen chain trimerization";"ECM proteoglycans";"Laminin interactions";"Collagen degradation";"NCAM1 interactions";"Anchoring fibril formation";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Extracellular matrix organization" XP_028896400.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011188829.1 14 MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-7409 "Anandamide biosynthesis II";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_011192811.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_011177909.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_011190187.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011190316.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_011182813.1 25 Reactome: R-HSA-8940973;Reactome: R-HSA-8931987;Reactome: R-HSA-8941284;Reactome: R-HSA-8935964;Reactome: R-HSA-8941858;Reactome: R-HSA-8936459;Reactome: R-HSA-8951911;Reactome: R-HSA-8877330;Reactome: R-HSA-8939242;Reactome: R-HSA-8939902;Reactome: R-HSA-8939243;Reactome: R-HSA-8878166;Reactome: R-HSA-8941333;Reactome: R-HSA-8941332;Reactome: R-HSA-8934593;Reactome: R-HSA-8941326;Reactome: R-HSA-8939256;Reactome: R-HSA-8939247;Reactome: R-HSA-8951936;Reactome: R-HSA-8949275;Reactome: R-HSA-8939246;Reactome: R-HSA-8939245;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236 "RUNX2 regulates osteoblast differentiation";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates expression of components of tight junctions";"Regulation of RUNX3 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX2 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional regulation by RUNX2";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates p14-ARF";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in BCR signaling";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_011182305.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168 "CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028900865.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011194075.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_011189826.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_011191618.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_011184743.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_011190780.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011184095.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_011188370.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_028900739.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_028895694.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011178933.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification" XP_011185643.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_011181073.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_011189566.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_011189811.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3371453 "SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response" XP_011195361.1 9 MetaCyc: PWY-6147;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_011180333.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_028900215.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_028895058.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011182495.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110312 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1" XP_011195385.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011180719.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028899603.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028901083.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" XP_011177276.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011195757.1 5 Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)" XP_028894829.1 57 Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870 "Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Neutrophil degranulation";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins" XP_028901826.1 17 MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-5532;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-6608;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611 "Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Purine catabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V" XP_028897388.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011194183.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_011192431.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409 "Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis" XP_011193432.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis" XP_011181566.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978 "ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_028895749.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_011190633.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_011183699.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011186399.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_011193929.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_011194286.1 5 MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)" XP_011180752.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011179458.2 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_011194250.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011192002.1 57 Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577 "Downstream TCR signaling";"Neutrophil degranulation";"G2/M Checkpoints";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Neddylation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21" XP_028900447.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_028895195.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028894612.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011193974.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism" XP_028893831.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011178168.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_028901473.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028897061.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011197063.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_028898441.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_011193107.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_011196457.1 4 KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Selenoamino acid metabolism" XP_028897654.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424 "SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling" XP_011187412.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_011189612.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_011177994.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_028898449.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011189298.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_028899709.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028897781.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028898378.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_011195833.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011181409.1 12 Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287 "TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery" XP_011194691.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "mTORC1-mediated signalling";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_028895310.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_011189136.1 15 Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-4641262 "S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_028893694.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_011189211.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972 "Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_011193472.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_011195431.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028900068.1 10 Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-917729;Reactome: R-HSA-5689880 "Inhibition of membrane repair";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases" XP_028894622.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_028896078.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_011177349.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_011185571.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_011189490.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_011193514.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011194557.1 4 Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108 "Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis" XP_028898420.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_011177228.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_011177751.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_028900030.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028897023.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_011180002.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_011182297.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_028899294.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_011189682.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_028896451.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011190154.1 12 Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane" XP_011193032.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-5651801 "POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair" XP_011188793.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_011190764.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_011186517.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_028895226.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028901008.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_011196612.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660 "Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway" XP_028902179.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011177428.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_028893703.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_011193345.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_028893643.1 22 Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion" XP_011178112.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_011186233.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028900464.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011190060.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_011195327.1 10 MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6527;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification" XP_011181710.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation" XP_011196251.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788 "TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_011194930.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_011192895.1 4 Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane" XP_011184210.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-174184 "Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_028900459.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_011192190.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_028900095.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_028897062.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011178760.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011191438.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011184338.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_028896327.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_028894734.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_011192249.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011189244.1 14 Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation" XP_028898792.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011176787.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_011191907.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028898603.1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_028897882.1 11 KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;Reactome: R-HSA-71403 "Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)" XP_011177965.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_028893698.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_028894210.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011187901.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028897310.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_028900259.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011193060.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation" XP_028896101.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6606;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608 "Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III" XP_011176801.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_028901605.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_011183739.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_028896129.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011177728.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs" XP_028898999.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_028895958.1 56 Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113 "Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1" XP_011184055.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_011180631.1 4 Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_011194007.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_011184727.1 7 KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;Reactome: R-HSA-2160456 "Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylketonuria" XP_028899182.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_011184639.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_011185470.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)" XP_011195995.1 7 KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-446205 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose" XP_011187977.1 4 MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_011181704.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_028900212.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_028893651.1 22 Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-432142 "CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL" XP_028899850.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894032.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011179401.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_028894049.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_011184553.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011191795.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_011192729.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_011178579.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011183134.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246 "Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript" XP_011178848.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011192570.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028898701.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" XP_011184059.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_028899713.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_028895330.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_011187086.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028894400.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_028894866.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011187191.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011192888.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684 "Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state" XP_011188886.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011192108.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_011192251.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_028898962.1 9 MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism" XP_028895780.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_028901778.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011187695.1 4 MetaCyc: PWY-7927;KEGG: 00920+2.8.1.1;Reactome: R-HSA-1614558;MetaCyc: PWY-5350 "Sulfide oxidation IV (mitochondria)";"Sulfur metabolism";"Degradation of cysteine and homocysteine";"Thiosulfate disproportionation IV (rhodanese)" XP_011187107.1 12 Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700 "Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_028898215.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011186677.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011177575.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_028894310.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017 "NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_011190552.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_011187015.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011184588.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_028895538.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_028897579.1 18 MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783 "Anandamide biosynthesis I";"Linoleic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation" XP_011190598.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011194974.1 22 MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-7053;MetaCyc: PWY-7726;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7725;MetaCyc: PWY-7035 "Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_028894700.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_011177120.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_028894507.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011195628.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_011185210.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_011179058.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028896686.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011193002.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011188717.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011187815.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_011183942.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011189577.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_028896344.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011182298.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_011186708.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180779.1 11 Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_011194269.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011189508.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028897064.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011194394.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_028897537.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_028898744.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_011194971.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180284.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_011180567.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events" XP_011197054.1 14 Reactome: R-HSA-75896;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.42;KEGG: 00564+2.3.1.15;Reactome: R-HSA-9033241;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782 "Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Peroxisomal protein import";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis" XP_011187061.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_011192801.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits" XP_011177160.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_028900609.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011178735.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011188021.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_011177178.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_011190508.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011187549.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_011186830.1 8 MetaCyc: PWY-5394;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;Reactome: R-HSA-209905;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2 "Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis II";"Folate biosynthesis" XP_011182733.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_011190245.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_011190661.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011193877.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_011178410.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_011183151.1 26 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-190840 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"RHO GTPases Activate Formins";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_011195427.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028894135.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_011176463.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_028895050.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_011186215.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_011194622.1 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_028894171.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_011184778.1 29 Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210 "Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_011176775.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028901357.1 8 KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_028899501.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-8948751 "Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Protein ubiquitination";"Regulation of PTEN stability and activity" XP_028897202.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028894260.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_028895750.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_011192677.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_011178711.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_011196084.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_011190183.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028896046.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011188850.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011188007.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011189785.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_011190138.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011177686.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011184514.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_028901278.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-381340 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_011191871.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_011187304.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028900545.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_011195772.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028898998.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_011184063.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011194043.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_011186418.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028899519.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_028900568.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_011183350.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_011180971.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_011185693.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_011191853.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_028896689.1 19 Reactome: R-HSA-70263;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-8086;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37 "Gluconeogenesis";"Methane metabolism";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms" XP_011189580.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_028901024.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_011189786.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_011187509.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_028899996.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_011196674.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_011190684.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_011189569.1 6 Reactome: R-HSA-2173796;Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011189924.2 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_011191598.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011177731.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis" XP_028900795.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_011182062.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_028897203.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011188211.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_011178730.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_028898143.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_011192207.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011188900.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258 "Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL" XP_011193775.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011185447.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_011184552.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011178762.2 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011187095.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_011184508.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_011189683.1 16 Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-9018519;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693565 "HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Estrogen-dependent gene expression";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_011196459.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011192362.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028901993.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011193862.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_011189629.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_028895476.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_011191496.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011192301.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_011179579.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011187143.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_011184763.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_028900546.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_028898164.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011187044.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011184538.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic" XP_011192252.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_028897622.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011187384.1 18 MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5913;MetaCyc: PWY-6638 "(R)-cysteate degradation";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III" XP_011192637.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011191845.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895223.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028894688.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011189689.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_028893596.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_011186904.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_011185482.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_011179374.2 57 Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258 "Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL" XP_028899906.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_011187842.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_011176909.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69205 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"G1/S-Specific Transcription" XP_028902152.1 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_028896818.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_011179607.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-264870 "Neutrophil degranulation";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins" XP_028894185.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028897377.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011180782.1 4 KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943 "Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates" XP_011181596.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011196013.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028901800.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028899398.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011190358.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_011185422.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_011177083.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_028900529.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_028900982.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028901534.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_028895043.1 24 Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-392451;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-5218920;Reactome: R-HSA-5218921;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;Reactome: R-HSA-5607764 "RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"PIP3 activates AKT signaling";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"FCERI mediated NF-kB activation";"VEGFR2 mediated vascular permeability";"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"CLEC7A (Dectin-1) signaling" XP_011180361.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_028899052.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_028894518.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028898033.1 13 Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-5607764 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling" XP_011187201.1 6 MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis" XP_011187004.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_011190529.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028893835.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921 "Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation" XP_028897863.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_011180007.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_028893632.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011183878.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011179168.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_028896349.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011189789.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_011182473.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692 "Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation" XP_011192149.1 6 Reactome: R-HSA-390247;Reactome: R-HSA-9603798;Reactome: R-HSA-5684045;Reactome: R-HSA-2046106;Reactome: R-HSA-1369062;Reactome: R-HSA-2046105 "Beta-oxidation of very long chain fatty acids";"Class I peroxisomal membrane protein import";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"alpha-linolenic acid (ALA) metabolism";"ABC transporters in lipid homeostasis";"Linoleic acid (LA) metabolism" XP_011193646.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_011190885.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011196168.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_028893649.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752 "S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated" XP_011188921.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_011186678.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011193539.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011186515.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011182306.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_028899980.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_028898666.1 14 Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416 "Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_011193575.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_028896338.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011182759.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_011194077.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_011197039.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_011192921.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_028901920.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418594 "PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation";"G alpha (i) signalling events" XP_028896838.1 56 Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-350562 "Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)" XP_028896578.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011191535.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028901377.1 12 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling" XP_011191931.1 8 MetaCyc: PWY-5739;Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-7573 "GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis" XP_011188899.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011187770.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028894601.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging" XP_011196055.1 14 MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51 "Anandamide biosynthesis II";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism" XP_011195416.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_011183617.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028902120.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011190277.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_011190902.1 5 MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)" XP_011196676.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_028899295.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_028896336.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011191500.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_028894191.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028895337.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555 "Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events" XP_011189139.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_011195129.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011181822.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011195515.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011190144.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_028901917.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events" XP_028894955.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_028900735.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_028895760.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_011183736.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011183282.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028902122.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_028902130.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_011193765.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_028898357.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation" XP_028898573.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_028898770.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_011178468.1 5 Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_011190691.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011185544.1 7 KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I";"UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_011189071.1 11 MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-7821;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-5695 "Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Tunicamycin biosynthesis";"Purine metabolism";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation I";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation" XP_011182021.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation" XP_028901935.1 12 KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343 "Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Glycogen synthesis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I" XP_011188719.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_011191923.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_011178405.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_028898070.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_028894641.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011190960.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_028894169.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_011196292.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_028896974.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_011176545.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011179577.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_028901939.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011178416.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011184586.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_028893849.1 9 Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_011190544.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_028898779.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_028895751.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_011178297.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_011180088.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011195465.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011191440.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_028897922.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_011181235.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_011177084.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-3214842 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones" XP_011177604.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_028896684.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011178126.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_011180781.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-174154 "Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin" XP_011195018.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_011192736.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011191887.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_011182939.1 10 KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_028895774.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011178749.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028897557.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_028900997.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-9617629 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation" XP_011176544.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011179399.2 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_011183357.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011196174.1 5 KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289 "Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Petrobactin biosynthesis" XP_011186451.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-159230 "Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA" XP_011191910.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_028897026.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036 "Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II" XP_011190597.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011191674.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_028900846.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011193831.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_028899959.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_011184661.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011184988.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_011179254.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011195467.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011184077.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011190375.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism" XP_011184213.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_028900880.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852 "Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy" XP_011179338.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_028893479.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028894023.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011188252.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_011177842.1 10 Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-427413 "MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression" XP_011177312.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_028896887.1 3 Reactome: R-HSA-5083635;Reactome: R-HSA-189085;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins" XP_028902036.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011185752.1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_028901806.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028899890.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011191358.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_028896341.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011190856.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_011186234.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_011187388.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_011194714.1 8 KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5173105 "Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation" XP_011186689.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028895448.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011182869.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation" XP_011179508.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011180675.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011196653.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011181599.1 33 Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-69273;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-69656;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-69231;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-73772 "Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_011181645.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_011194335.1 6 Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;MetaCyc: PWY-7511 "Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Protein ubiquitination" XP_011186593.1 40 Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167243 "Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery" XP_011186017.2 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation" XP_028901511.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-7587 "Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_011183467.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_011177587.1 3 Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389 "Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases" XP_028901135.1 12 KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4 "Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism" XP_028894254.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011195025.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_011179877.2 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_011192635.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_011178615.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011188348.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_011195066.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011188258.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_011192502.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_028900869.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_011181650.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_011178195.1 10 MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1 "Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Fructose and mannose metabolism" XP_028901893.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_011192353.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005 "Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+" XP_011181234.1 25 Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-381771;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-381676 "Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_028898020.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_028898032.1 6 MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis" XP_011196153.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_028895767.1 13 Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097 "RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway" XP_011186235.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_028899777.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_028897974.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011181583.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_028901378.1 12 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_028896334.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011177227.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_028893873.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607 "Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends" XP_011195557.1 17 MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-4202;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1 "Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Purine metabolism";"Purine catabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II" XP_028896065.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011181523.1 10 MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524 "Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Butanoate metabolism";"Mevalonate pathway III (archaea)" XP_011185819.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011187637.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011196691.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_028899886.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011178110.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011184897.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_028894399.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_011190705.2 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011190003.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_011183397.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_028898011.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_011192189.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_011188812.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028895811.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-180910 "Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs" XP_028899978.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_011192218.1 5 Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_028894500.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_011183581.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011180336.1 3 Reactome: R-HSA-71262;MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8 "Carnitine synthesis";"L-carnitine biosynthesis";"Lysine degradation" XP_028895695.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011184932.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_011184441.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_028900493.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011197004.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011176830.1 8 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;Reactome: R-HSA-5083633 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_028896840.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837 "Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation" XP_011193967.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_011188409.1 8 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_011188764.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_011181264.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_028898851.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_011187554.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011193308.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011178918.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_011180217.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011194987.1 7 MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836;MetaCyc: PWY-7838;Reactome: R-HSA-1660662 "Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism" XP_028902231.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_011191536.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011187042.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011193502.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_028899747.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011186351.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_011185987.1 5 Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853 "Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)" XP_011182758.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_028894329.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_028900794.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_011176540.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011179814.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181148.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_011183473.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_028898314.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_011181618.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_028901384.1 12 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-429947 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA" XP_028898443.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_011188825.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011190890.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_011192168.1 9 Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237 "Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2" XP_011196577.1 13 Reactome: R-HSA-8866654;Reactome: R-HSA-5358346;Reactome: R-HSA-110320;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-5689877;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog ligand biogenesis";"Translesion Synthesis by POLH";"Protein methylation";"Ovarian tumor domain proteases";"Josephin domain DUBs";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Neutrophil degranulation";"HSF1 activation";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_028897957.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011182160.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_028894689.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011197080.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_011188352.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_011182416.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577 "Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21" XP_028899550.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_028899425.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_028896773.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_028900932.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_011189842.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_028895667.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-432040 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_011182922.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"Macroautophagy" XP_011186088.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_011194118.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011187595.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-400206 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha" XP_011180058.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_028900032.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028900550.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_011195352.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_011193033.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_028899994.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_028895269.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_011187720.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_028899151.1 17 Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-75035;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Signaling by SCF-KIT";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Thermogenesis";"Activation of ATR in response to replication stress";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_011189582.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_028897590.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011186094.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011178832.1 7 Reactome: R-HSA-418594;Reactome: R-HSA-140837;Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_011182675.1 3 Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_011189302.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_028896104.1 12 Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-177929;Reactome: R-HSA-2122948 "Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"TNF signaling";"Regulated proteolysis of p75NTR";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_011182484.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011189571.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_011190624.1 9 Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962 "CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex" XP_028896665.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_011178897.1 3 MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)" XP_011181640.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_028895461.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513 "Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling" XP_028901355.1 8 KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1 "Fructose and mannose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_028895242.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_011190426.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011188868.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_011181146.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_011184007.1 52 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-73980;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167287 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Termination";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery" XP_028895513.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028901006.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_011183477.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011196649.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_011183597.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_011191441.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181430 "Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_028897402.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_011191524.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-389957 "Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_011183440.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_028897788.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011176835.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011188278.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_028900476.1 11 Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475 "HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_011182436.1 5 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_011187659.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_011181744.1 13 KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101 "Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation" XP_028898602.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_028900837.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_028899985.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_028901541.1 22 MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7049;MetaCyc: PWY-7606;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7727;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7726 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_011177822.2 5 MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761 "Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)" XP_011178608.1 7 Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472 "HCMV Early Events";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011193049.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-167238 "HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_011177504.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_028898415.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_028899119.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" YP_004891177.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_011178567.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011185071.1 11 MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539 "L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism" XP_011190439.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_011189170.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_028894193.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028897887.1 3 MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695 "Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation" XP_028900867.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_028898097.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_028898348.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181594.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011186905.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_011187920.1 5 MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;Reactome: R-HSA-75896 "Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis" XP_028895612.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011180090.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_028895354.1 4 KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_028901571.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_011196399.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_011185774.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011179235.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011188291.1 30 Reactome: R-HSA-389357;Reactome: R-HSA-9614399;Reactome: R-HSA-69202;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-199418;Reactome: R-HSA-6804758;Reactome: R-HSA-198323;Reactome: R-HSA-6804759;Reactome: R-HSA-9634638;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-8876198;Reactome: R-HSA-111447;Reactome: R-HSA-389513;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-392451 "CD28 dependent PI3K/Akt signaling";"Regulation of localization of FOXO transcription factors";"Cyclin E associated events during G1/S transition";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"AKT phosphorylates targets in the nucleus";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Activity through Acetylation";"AKT phosphorylates targets in the cytosol";"Regulation of TP53 Activity through Association with Co-factors";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"RAB GEFs exchange GTP for GDP on RABs";"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"RUNX2 regulates genes involved in cell migration";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Regulation of PTEN stability and activity";"G beta:gamma signalling through PI3Kgamma" XP_028900804.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-877300 "Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"HSF1-dependent transactivation";"Interferon gamma signaling" XP_028899421.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028901280.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-2426168 "PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)" XP_028893471.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_011195623.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_028894227.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_011191079.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_011194907.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_028897066.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011194381.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_011182375.1 9 MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533 "Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Glutathione conjugation";"Gliotoxin biosynthesis" XP_028895365.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011186347.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_028893700.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_011196783.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_028898310.1 18 MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4 "Anandamide biosynthesis I";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism" XP_011191195.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011182596.1 9 Reactome: R-HSA-2173791;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_011179409.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" XP_011188840.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011196573.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-442720 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_011178270.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_011184708.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099 "Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling" XP_011193219.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_011189846.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_011185127.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011176528.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028896742.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_028896461.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011194123.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_011187829.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_011189122.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_011177364.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011180633.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011193943.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_028894928.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_028896563.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_011185559.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" YP_004891166.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_011184346.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011193908.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_011193044.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011183479.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011194587.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011183341.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_011180501.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011195144.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944 "Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2" XP_011180929.1 14 Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290 "Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation" XP_011183114.1 5 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)" XP_011183703.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_011192568.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028901839.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011193910.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_028899109.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_011191540.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_011189072.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_028895049.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_011177940.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_028899181.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_028894211.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011185129.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_028900781.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_028898366.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011193564.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_011188243.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665 "Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells" XP_028894884.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_011191353.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_011181126.1 10 Reactome: R-HSA-4719377;Reactome: R-HSA-913709;MetaCyc: PWY-7661;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83 "Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis" XP_011196559.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011191704.2 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_011180750.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011177323.1 16 MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.4;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969 "Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_011180741.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_011178675.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011191095.1 3 Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691 "Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling" XP_028900421.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_011190233.1 8 Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472 "PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_011187393.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_011180178.1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response" XP_028901047.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_011195215.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_011190196.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_011185159.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011193017.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_011179553.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916 "MPS VII - Sly syndrome";"HS-GAG degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation" XP_011183685.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_028900300.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_011197074.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028900935.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock" XP_011187073.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_011189810.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response" XP_011193590.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_011179007.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_028895759.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_028902113.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011196382.1 6 MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_028896941.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011179049.1 18 MetaCyc: PWY-5046;KEGG: 00310+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-71403;KEGG: 00260+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-204174;Reactome: R-HSA-6783984;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-70895;KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00380+1.8.1.4 "2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine degradation";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Glycine, serine and threonine metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation";"Pyruvate metabolism";"Propanoate metabolism";"Tryptophan metabolism" XP_011181527.1 10 MetaCyc: PWY-7391;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174 "Isoprene biosynthesis II (engineered)";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)" XP_011189232.1 10 KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4041 "Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle" XP_028896571.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_028898270.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_028895267.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_011195939.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation" XP_011190988.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028900862.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_011180318.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_011186511.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399 "Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_011189345.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_028898634.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_011190049.1 17 Reactome: R-HSA-1433557;Reactome: R-HSA-69601;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-75035;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187 "Signaling by SCF-KIT";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Transcriptional Regulation by E2F6";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Thermogenesis";"Activation of ATR in response to replication stress" XP_011180769.1 14 MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)" XP_011191629.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_028902169.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011185070.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011194743.1 24 KEGG: 04150+2.7.11.11;Reactome: R-HSA-381676;Reactome: R-HSA-8853659;Reactome: R-HSA-5610785;Reactome: R-HSA-5621575;Reactome: R-HSA-163560;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-5610783;Reactome: R-HSA-111931;Reactome: R-HSA-5610787;Reactome: R-HSA-163358;Reactome: R-HSA-983231;Reactome: R-HSA-422356;Reactome: R-HSA-5610780;Reactome: R-HSA-392517;Reactome: R-HSA-9634600;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-442720;Reactome: R-HSA-8963896;Reactome: R-HSA-9010642;Reactome: R-HSA-163615 "mTOR signaling pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"RET signaling";"GLI3 is processed to GLI3R by the proteasome";"CD209 (DC-SIGN) signaling";"Triglyceride catabolism";"DARPP-32 events";"PKA activation in glucagon signalling";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of CREB";"Hedgehog 'off' state";"PKA-mediated phosphorylation of key metabolic factors";"Factors involved in megakaryocyte development and platelet production";"Regulation of insulin secretion";"Degradation of GLI1 by the proteasome";"Rap1 signalling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"HDL assembly";"ROBO receptors bind AKAP5";"PKA activation" XP_028894777.1 10 Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-380972 "Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_028900604.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011180563.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011182914.1 14 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782 "Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PC";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Plasmalogen biosynthesis" XP_011183313.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_011196442.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_011194615.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108 "RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_011184311.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011186355.1 5 Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621 "Pyrimidine salvage";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine catabolism" XP_011178574.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011184258.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011180418.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_028894241.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011189799.1 10 MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-4321;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;MetaCyc: PWY-5022 "4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation II";"L-glutamate degradation IV";"4-aminobutanoate degradation III";"beta-Alanine metabolism";"Degradation of GABA";"Propanoate metabolism";"4-aminobutanoate degradation V" XP_011177028.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_011186507.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_011193059.1 20 MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-6920 "Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)" XP_028898892.1 6 KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_028899120.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_011193662.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_011178134.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_011192665.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028896363.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011195189.1 5 KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20 "Carbon fixation pathways in prokaryotes";"Folate transformations I";"Metabolism of folate and pterines";"Folate transformations II (plants)";"One carbon pool by folate" XP_011197008.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011182565.1 6 KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11 "Methane metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis" XP_011189169.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_011177786.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028901354.1 8 KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171 "Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_028897674.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_011181345.1 1 Reactome: R-HSA-419771 "Opsins" XP_028900247.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_011192150.1 6 Reactome: R-HSA-390247;Reactome: R-HSA-9603798;Reactome: R-HSA-1369062;Reactome: R-HSA-2046106;Reactome: R-HSA-5684045;Reactome: R-HSA-2046105 "Beta-oxidation of very long chain fatty acids";"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis";"alpha-linolenic acid (ALA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Linoleic acid (LA) metabolism" XP_028896201.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_028894896.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_011190258.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011194876.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011176891.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011176423.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028900309.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_011193212.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-166208 "Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling" XP_011176508.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011176421.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_011184204.1 9 MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_011185926.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_028896958.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_011197070.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_028894628.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702 "SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling" XP_028899275.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_011191641.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_011181565.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011184859.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_011195429.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_011191460.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028894188.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_028899552.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043 "G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events" XP_011179207.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_011192004.1 19 Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423 "Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"Chylomicron clearance";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"VLDL clearance";"VLDL assembly" XP_011183412.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011193945.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_028901544.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits" XP_028894627.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-9020702 "SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling" XP_011181463.1 16 Reactome: R-HSA-166058;Reactome: R-HSA-6811558;Reactome: R-HSA-5603037;Reactome: R-HSA-3134963;Reactome: R-HSA-1236974;Reactome: R-HSA-975110;Reactome: R-HSA-975155;Reactome: R-HSA-209543;Reactome: R-HSA-975138;Reactome: R-HSA-5602498;Reactome: R-HSA-1257604;Reactome: R-HSA-975871;Reactome: R-HSA-9020702;Reactome: R-HSA-5602680;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"ER-Phagosome pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR2/4)";"PIP3 activates AKT signaling";"MyD88 cascade initiated on plasma membrane";"Interleukin-1 signaling";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1" XP_011196001.1 12 Reactome: R-HSA-1912408;Reactome: R-HSA-73762;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856 "Pre-NOTCH Transcription and Translation";"RNA Polymerase I Transcription Initiation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling" XP_011193889.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028898776.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011181756.1 13 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_011187624.2 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_028899786.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_028897313.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_011193140.1 52 Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-5250924;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-167242 "Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"B-WICH complex positively regulates rRNA expression";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_011186417.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028898773.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_011177829.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_028899984.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_028901587.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_028902244.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011181037.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_011196501.1 4 KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_028894206.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011183405.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011185441.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_011190256.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011192110.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_011188345.1 3 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_011177480.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_011186577.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_028895728.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_011177164.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway" XP_011187283.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" YP_004891168.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_011183608.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695 "HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_011188874.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_028896778.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_011193067.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237 "Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"HS-GAG biosynthesis";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2" XP_011178440.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028900319.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_011176893.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_011194180.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_011181713.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695 "Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation" XP_011178993.1 9 KEGG: 00350+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5 "Tyrosine metabolism";"Cysteine and methionine metabolism";"Tyrosine catabolism";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism" XP_011196928.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_011196874.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_028898680.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_028900708.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011195154.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes" XP_028897215.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028901840.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_011187572.1 4 MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism" XP_028896479.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_011192298.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_011189019.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_011177117.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011179218.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011179328.1 57 Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236 "Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_028898439.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_011190502.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011181347.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_028899933.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_011183978.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_011189315.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028898968.1 10 MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-3841 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Folate transformations II (plants)" XP_011188113.1 5 Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780 "GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome" XP_028897071.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011187578.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011178852.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_011189291.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011195566.1 13 KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5133 "Pyruvate metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Ethanol oxidation";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis" XP_011184535.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028898847.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011192299.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_011179467.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_011184195.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_011186912.1 11 MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7124;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;Reactome: R-HSA-71403 "TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)" XP_011181378.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_028896066.1 6 MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622 "Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)" XP_011188262.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_011195952.1 7 MetaCyc: PWY-6605;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;Reactome: R-HSA-6798695 "Adenine and adenosine salvage II";"Adenine salvage";"Purine salvage";"Glyphosate degradation III";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation" XP_028900222.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_028900979.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983 "ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)" XP_028898969.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011178605.1 13 KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_011188118.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_028896372.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011196271.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011178193.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_011181674.1 6 MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_011193158.1 33 Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-168325 "NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis" XP_011186353.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_011190162.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_028896900.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028898408.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011184856.1 7 MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine metabolism" XP_028897517.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028896631.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_011178442.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028897214.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028894837.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_028899974.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011185578.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_028894897.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_011187952.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028900008.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_011185563.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_028894314.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011192673.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_028900261.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028898398.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis" XP_011178667.1 8 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387 "ATP biosynthesis";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Photosynthesis";"Insulin receptor recycling" XP_011177296.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_028895947.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011186018.1 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" XP_011187046.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011180639.1 13 MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Citrate cycle (TCA cycle)" XP_011186421.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028896227.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_011177845.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_011176834.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_028896723.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695 "Keratan sulfate degradation";"Glycosphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Sialic acid metabolism";"Sphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation" XP_011191991.1 2 Reactome: R-HSA-8981607;Reactome: R-HSA-203615 "Intracellular oxygen transport";"eNOS activation" XP_011179977.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028898015.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_028896940.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011181525.1 10 MetaCyc: PWY-7391;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-6174 "Isoprene biosynthesis II (engineered)";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)" XP_011189550.1 10 Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-611105 "Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport" XP_028900262.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011177430.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_028896202.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_028896302.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_011188527.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_011177837.1 10 Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-427413 "MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression" XP_028894776.1 10 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_011186332.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_011182296.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_011192262.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_011195168.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_011182956.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028893683.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_011191391.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_011192666.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011185766.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011176713.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_011187074.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_011192810.1 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes" XP_011181843.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011178239.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899604.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028898233.1 6 Reactome: R-HSA-5083625;Reactome: R-HSA-913709;Reactome: R-HSA-5621480;Reactome: R-HSA-977068;Reactome: R-HSA-5083636;Reactome: R-HSA-5083632 "Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)";"O-linked glycosylation of mucins";"Dectin-2 family";"Termination of O-glycan biosynthesis";"Defective GALNT12 causes colorectal cancer 1 (CRCS1)";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_011187840.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028895843.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane" XP_028899370.1 17 MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Candicidin biosynthesis";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes" XP_011180612.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_028895459.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-68877 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase" XP_011181856.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_028900895.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_028894528.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011177805.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_011189555.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_028895887.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_011185126.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_011177700.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_011182587.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_028899963.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_011187646.1 30 Reactome: R-HSA-5676590;Reactome: R-HSA-69231;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2644607;Reactome: R-HSA-187577;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2565942;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2894862;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050 "NIK-->noncanonical NF-kB signaling";"Cyclin D associated events in G1";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF(Skp2)-mediated degradation of p27/p21";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of PLK1 Activity at G2/M Transition";"Prolactin receptor signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_028894356.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_011195613.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011188918.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1 "Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_011181958.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" XP_011179263.1 1 Reactome: R-HSA-419771 "Opsins" XP_011180957.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_011184345.1 14 MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_011190084.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011187289.1 13 MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-8086;Reactome: R-HSA-71403 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)" XP_011196842.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011177815.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011189867.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_028898946.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_011185610.1 10 Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590 "CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling" XP_011196063.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_011187669.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_011184196.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_011194511.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle" XP_011180236.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011194507.1 9 MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-7902;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94 "CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism" XP_028901415.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_028895961.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028898158.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_028902045.1 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122 "Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis" XP_011181847.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_011180089.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_028899965.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_028896718.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_028895691.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011196845.1 3 KEGG: 00330+2.3.1.57;MetaCyc: PWY-0;MetaCyc: PWY-6117 "Arginine and proline metabolism";"Putrescine degradation III";"Spermine and spermidine degradation I" XP_011188745.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_028902117.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011195626.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_011195719.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028896350.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011179851.1 10 Reactome: R-HSA-977225;Reactome: R-HSA-2453864;KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;MetaCyc: PWY-5691;MetaCyc: PWY-7849;MetaCyc: PWY-7394 "Amyloid fiber formation";"Retinoid cycle disease events";"Purine metabolism";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Urate conversion to allantoin II" XP_011187043.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028899371.1 17 KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-4381;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780 "Fatty acid biosynthesis";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Biotin transport and metabolism" XP_028901780.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_011180964.1 11 MetaCyc: PWY-6607;MetaCyc: PWY-6538;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-6596;MetaCyc: PWY-6606;Reactome: R-HSA-74259 "Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine catabolism" XP_028894216.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011178598.1 56 Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases" XP_011179222.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028897123.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_011180504.1 6 KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis" XP_011184964.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_011178962.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011177893.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_028900036.1 6 Reactome: R-HSA-1369062;Reactome: R-HSA-2046106;Reactome: R-HSA-5684045;Reactome: R-HSA-2046105;Reactome: R-HSA-390247;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"alpha-linolenic acid (ALA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Linoleic acid (LA) metabolism";"Beta-oxidation of very long chain fatty acids";"Class I peroxisomal membrane protein import" XP_011181397.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_028894411.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_028900238.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_011188285.1 30 Reactome: R-HSA-8941332;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8948751;Reactome: R-HSA-392451;Reactome: R-HSA-9634638;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-8876198;Reactome: R-HSA-111447;Reactome: R-HSA-389513;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-198693;Reactome: R-HSA-6804758;Reactome: R-HSA-198323;Reactome: R-HSA-6804759;Reactome: R-HSA-389357;Reactome: R-HSA-9614399;Reactome: R-HSA-69202;Reactome: R-HSA-5218920 "RUNX2 regulates genes involved in cell migration";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN stability and activity";"G beta:gamma signalling through PI3Kgamma";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"RAB GEFs exchange GTP for GDP on RABs";"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Activity through Acetylation";"AKT phosphorylates targets in the cytosol";"Regulation of TP53 Activity through Association with Co-factors";"CD28 dependent PI3K/Akt signaling";"Regulation of localization of FOXO transcription factors";"Cyclin E associated events during G1/S transition";"VEGFR2 mediated vascular permeability" XP_011190170.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_011180942.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_011187575.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism" XP_011195309.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_011182674.1 3 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_028894822.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_011191056.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_011189088.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426486 "Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis" XP_011189242.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028894662.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028895593.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_011192244.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_011192797.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011184771.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_028899209.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028897459.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_011178914.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028894125.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011182051.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_011195574.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011179478.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-437239 "RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1" XP_011187843.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011183901.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011178806.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_028895952.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011183787.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_011189498.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_011180411.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_028899770.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane" XP_028897880.1 6 Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993 "Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors" XP_028900806.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-936837 "Interferon gamma signaling";"HSF1-dependent transactivation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases" XP_011192663.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_028895592.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_028897588.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011183570.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011193125.1 8 KEGG: 04660+3.1.3.16;KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"Glycerophospholipid metabolism";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation" XP_028896905.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_011184766.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_011189958.1 3 Reactome: R-HSA-4085001;MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38 "Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis" XP_011192892.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" XP_011176600.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_011187010.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_011179600.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011190374.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_011177454.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism" XP_028901418.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011195387.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_028899704.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011193354.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_011188723.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_011184604.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_011177054.1 5 Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442 "VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs" XP_011187390.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_011178747.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_011176972.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028894186.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011181517.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011196558.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011188893.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_011177410.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011177493.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028899268.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_011178630.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_011184883.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state" XP_028900829.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011193449.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_011190402.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_011184712.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972 "Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_011178917.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_011179133.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_028901558.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_011184042.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_011187379.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_011182361.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379 "Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans";"Molecules associated with elastic fibres" XP_028894510.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_011177692.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011184076.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011194538.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_028897700.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_011193616.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_011181962.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011181764.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_011195054.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_028901689.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011186001.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_028897765.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464 "Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins" XP_011196998.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-2029485 "Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis" XP_011182873.1 3 Reactome: R-HSA-8964058;Reactome: R-HSA-1369062;Reactome: R-HSA-9029569 "HDL remodeling";"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_028898633.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_011192998.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011195689.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" YP_004891176.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028900608.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011181002.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011193797.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_011177457.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011193860.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440 "Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_011193786.1 10 KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-5368286;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1 "Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Mitochondrial translation initiation";"Glycolysis / Gluconeogenesis";"Mitochondrial translation elongation";"Mitochondrial translation termination";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_011183116.1 5 MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_028901842.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_011186897.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_011188481.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_011176800.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_028902232.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_011193272.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_028897204.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028899700.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011187844.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028896286.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011184316.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011190656.1 17 MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780 "Jadomycin biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Biotin transport and metabolism" XP_011178184.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_011180265.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011185468.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_011188057.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_011190041.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_011184384.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_028900838.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_011185330.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028900745.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_028899500.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011183527.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_011186329.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_011188605.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_011189635.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_011177265.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_011188628.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159231 "Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_028893877.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-69473;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Protein ubiquitination" XP_028901035.1 7 KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11 "Fructose and mannose metabolism";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms" XP_011181940.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_028899971.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_011177458.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_011193358.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_028901595.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_028897868.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_011178256.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_011192752.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_028899133.1 8 Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-9627069 "Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity" XP_011192634.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181407.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_011192669.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011185630.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_028896079.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_011178402.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_011186516.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_028897783.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_028894527.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_028894245.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011191854.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_028893875.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693565;MetaCyc: PWY-7511 "Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination" XP_028896757.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Activation of RAC1";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_028900297.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_011178281.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_028894778.1 10 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_011181759.1 13 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416572;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"RHO GTPases Activate ROCKs";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011179532.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_011195758.1 5 Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35 "Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"Vitamin B6 metabolism" XP_011187947.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028895943.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028901559.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_011188192.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676 "Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle" XP_011182526.1 5 Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604 "PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling" XP_011178957.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011191703.2 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_028902119.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_028896710.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_028896360.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_028895917.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_028896337.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_028898451.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_028900423.1 3 Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane" XP_011189086.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944 "Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2" XP_028896405.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011185456.2 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_011187334.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_028893697.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_011180110.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_028901381.1 12 Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_028895487.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_011191302.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_011187069.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_011183058.1 4 Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5689880 "Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases" XP_011183958.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_011182155.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011190497.1 4 MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_028898167.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_011184064.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_028900814.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_011190657.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011187565.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011192373.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_011183669.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_028895939.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028896777.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_011180548.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_011189797.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_028899456.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011180133.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_028894951.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_028899364.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011193312.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972 "Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)" XP_028895820.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_011180708.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011197107.1 9 KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_011186749.1 13 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-182218 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation" XP_028898526.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_028899758.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_028895324.1 15 MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-7218 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Purine metabolism";"Glycolysis";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_011184340.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011178831.1 15 KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40 "Purine metabolism";"Glycolysis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis" XP_011176527.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028894706.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011186574.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_011187181.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011190993.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011187285.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_028895268.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_028893952.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_011184203.1 9 Reactome: R-HSA-196780;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146 "Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism" XP_011184040.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_011195632.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_028894475.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_011191742.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Synthesis of PA" XP_028895878.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_011194395.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_011179025.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_028900422.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011180247.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_011182785.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011195044.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011183900.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011195616.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028898520.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_028901619.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_011188950.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_028896373.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011187819.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_011186026.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_028901972.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_028895604.1 15 Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519 "Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression" XP_011179308.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_028893816.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011179195.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028901139.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_011194272.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" XP_028902022.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type" XP_011190359.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_011180623.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_028901263.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_011179651.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_011190651.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_028898495.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_011176927.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_011184930.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_011193425.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_028898028.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-975577;Reactome: R-HSA-913709 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation";"O-linked glycosylation of mucins" XP_011190410.1 24 Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_011191726.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_011181740.1 13 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series" XP_028897065.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011188607.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_011189713.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_028896685.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011190556.1 4 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_028897460.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_028895272.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011189563.1 8 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_011190075.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_028900764.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_028894892.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_011186680.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028898191.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011189989.1 23 Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-500657 "G beta:gamma signalling through BTK";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"Ca2+ pathway";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors" XP_011194568.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011184593.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011195240.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011196234.1 1 Reactome: R-HSA-419771 "Opsins" XP_028896362.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011194014.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011186685.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_028896854.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-3000170;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-6794361;Reactome: R-HSA-212676;KEGG: 00230+2.7.4.8 "Nephrin family interactions";"Syndecan interactions";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Purine metabolism" XP_011180165.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_028900966.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6811440 "Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network" XP_028898662.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011187859.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011196346.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011180053.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011195558.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028894424.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_011193097.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011193526.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_028896367.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011179621.1 9 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"Orc1 removal from chromatin" XP_028899639.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028898890.1 6 Reactome: R-HSA-5654706;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712 "FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling" XP_028900791.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_028899343.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_011190261.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028902100.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-381676 "Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_028899616.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_011189117.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_028899601.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011192441.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361 "Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_028900402.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_011187361.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_028900591.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_011191516.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_011183877.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011184004.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_011177439.1 4 KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion" XP_011188989.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_011179875.2 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_011178734.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_028893701.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_011179456.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895738.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_011190259.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011190625.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_011176781.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011187154.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_011179608.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_011187561.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_011190498.1 4 MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87 "Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis" XP_011197127.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028898667.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_028900012.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_028894874.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_011178988.2 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_011187373.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011192989.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_028897052.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_028895253.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011181112.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_011188420.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028896706.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_028893527.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_028893545.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_011176478.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257 "S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion" XP_011178450.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_011195166.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_011186297.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_028893777.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_011191064.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-6814122 "Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_011196352.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_028901835.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_028899818.1 8 MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6609 "Adenine and adenosine salvage V";"Surfactant metabolism";"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Adenine and adenosine salvage III" XP_028899293.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_028898432.1 13 MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5030;Reactome: R-HSA-196757;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate polyglutamylation" XP_011189487.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011179551.1 10 Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Neutrophil degranulation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_011185284.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166 "Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate" XP_011191249.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_011177516.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_011178771.1 33 Reactome: R-HSA-113418;Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-69273;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-69656;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-69231;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Formation of the Early Elongation Complex";"Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_011184122.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Activation of RAC1";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_011190080.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_028898092.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_011192148.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_011188970.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits" XP_028896143.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028900750.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_028899787.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_011187661.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_011191822.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_011187772.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011185302.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_011194778.1 182 Reactome: R-HSA-2691232;Reactome: R-HSA-8866654;Reactome: R-HSA-2122947;Reactome: R-HSA-9637628;Reactome: R-HSA-5362768;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-209543;Reactome: R-HSA-8854050;Reactome: R-HSA-9033241;Reactome: R-HSA-9615710;Reactome: R-HSA-8863795;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-6781827;Reactome: R-HSA-72764;Reactome: R-HSA-180534;Reactome: R-HSA-5689896;Reactome: R-HSA-936440;Reactome: R-HSA-1234176;Reactome: R-HSA-975163;Reactome: R-HSA-5205685;Reactome: R-HSA-2122948;Reactome: R-HSA-937041;Reactome: R-HSA-209560;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-110314;Reactome: R-HSA-182971;Reactome: R-HSA-156827;Reactome: R-HSA-6804756;Reactome: R-HSA-450302;Reactome: R-HSA-5607761;Reactome: R-HSA-72649;Reactome: R-HSA-5357956;Reactome: R-HSA-349425;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-5689877;Reactome: R-HSA-5685942;Reactome: R-HSA-187577;Reactome: R-HSA-6782210;Reactome: R-HSA-445989;Reactome: R-HSA-3322077;Reactome: R-HSA-4608870;Reactome: R-HSA-2894862;Reactome: R-HSA-69541;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-912631;Reactome: R-HSA-975110;Reactome: R-HSA-3769402;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-9645460;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-110320;Reactome: R-HSA-8866652;Reactome: R-HSA-2173796;Reactome: R-HSA-936964;Reactome: R-HSA-174084;Reactome: R-HSA-917729;Reactome: R-HSA-400253;Reactome: R-HSA-975956;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-9633012;Reactome: R-HSA-5689901;Reactome: R-HSA-1799339;Reactome: R-HSA-4641258;Reactome: R-HSA-6783310;Reactome: R-HSA-9646399;Reactome: R-HSA-975957;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-6804760;Reactome: R-HSA-4641263;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5696400;Reactome: R-HSA-977225;Reactome: R-HSA-6804757;Reactome: R-HSA-5675482;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-2173788;Reactome: R-HSA-975144;Reactome: R-HSA-2871837;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-6782135;Reactome: R-HSA-2979096;Reactome: R-HSA-8875360;Reactome: R-HSA-5655862;Reactome: R-HSA-8849469;Reactome: R-HSA-1169408;Reactome: R-HSA-5675221;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-937042;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-205043;Reactome: R-HSA-5654733;Reactome: R-HSA-168638;Reactome: R-HSA-195253;Reactome: R-HSA-450321;Reactome: R-HSA-9013973;Reactome: R-HSA-75815;Reactome: R-HSA-174490;Reactome: R-HSA-5693607;Reactome: R-HSA-72689;Reactome: R-HSA-174113;Reactome: R-HSA-2672351;Reactome: R-HSA-5654732;Reactome: R-HSA-3785653;Reactome: R-HSA-6791226;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-5654726;Reactome: R-HSA-72706;Reactome: R-HSA-9636383;Reactome: R-HSA-9014325;Reactome: R-HSA-179409;Reactome: R-HSA-2644606;Reactome: R-HSA-8948751;Reactome: R-HSA-156902;Reactome: R-HSA-5693565;Reactome: R-HSA-162588;Reactome: R-HSA-5696397;Reactome: R-HSA-201681;Reactome: R-HSA-192823;Reactome: R-HSA-983168;Reactome: R-HSA-175474;Reactome: R-HSA-9013507;Reactome: R-HSA-5656121;Reactome: R-HSA-8876493;Reactome: R-HSA-1253288;Reactome: R-HSA-5676590;Reactome: R-HSA-3134975;Reactome: R-HSA-9010553;Reactome: R-HSA-9613829;Reactome: R-HSA-1295596;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-2559580;Reactome: R-HSA-5696394;Reactome: R-HSA-5357905;Reactome: R-HSA-2467813;Reactome: R-HSA-937072;Reactome: R-HSA-174154;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-532668;Reactome: R-HSA-110312;Reactome: R-HSA-450408;Reactome: R-HSA-174048;Reactome: R-HSA-2173791;Reactome: R-HSA-2173795;Reactome: R-HSA-5654727;Reactome: R-HSA-8948747;Reactome: R-HSA-5656169;Reactome: R-HSA-5658442;Reactome: R-HSA-168928;Reactome: R-HSA-901032;Reactome: R-HSA-8856825;Reactome: R-HSA-168927;Reactome: R-HSA-72702;Reactome: R-HSA-5696395;Reactome: R-HSA-2559585;Reactome: R-HSA-202424;Reactome: R-HSA-937039;Reactome: R-HSA-180585;Reactome: R-HSA-1358803;Reactome: R-HSA-1236382;Reactome: R-HSA-2565942 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"NOTCH1 Intracellular Domain Regulates Transcription";"Modulation by Mtb of host immune system";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"p75NTR recruits signalling complexes";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Peroxisomal protein import";"Late endosomal microautophagy";"Downregulation of ERBB2 signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Eukaryotic Translation Termination";"Vpu mediated degradation of CD4";"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"Activated NOTCH1 Transmits Signal to the Nucleus";"IKK complex recruitment mediated by RIP1";"NF-kB is activated and signals survival";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Recognition of DNA damage by PCNA-containing replication complex";"EGFR downregulation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of TP53 Activity through Phosphorylation";"activated TAK1 mediates p38 MAPK activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Translation initiation complex formation";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Josephin domain DUBs";"HDR through Homologous Recombination (HRR)";"SCF(Skp2)-mediated degradation of p27/p21";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Glycogen synthesis";"Asymmetric localization of PCP proteins";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Stabilization of p53";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Regulation of signaling by CBL";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Deactivation of the beta-catenin transactivating complex";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Alpha-protein kinase 1 signaling pathway";"Neddylation";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Autodegradation of Cdh1 by Cdh1:APC/C";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Circadian Clock";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Metalloprotease DUBs";"SRP-dependent cotranslational protein targeting to membrane";"Degradation of DVL";"Fanconi Anemia Pathway";"Aggrephagy";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Degradation of AXIN";"G2/M Checkpoints";"Regulation of TP53 Activity through Methylation";"Regulation of FZD by ubiquitination";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"MAPK6/MAPK4 signaling";"Dual Incision in GG-NER";"Amyloid fiber formation";"Regulation of TP53 Degradation";"Regulation of necroptotic cell death";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Downregulation of TGF-beta receptor signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Dual incision in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"InlB-mediated entry of Listeria monocytogenes into host cell";"Translesion synthesis by POLK";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"ISG15 antiviral mechanism";"Negative regulation of MAPK pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"IRAK2 mediated activation of TAK1 complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"NRIF signals cell death from the nucleus";"Negative regulation of FGFR4 signaling";"NOD1/2 Signaling Pathway";"Degradation of beta-catenin by the destruction complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin-dependent degradation of Cyclin D";"Membrane binding and targetting of GAG proteins";"Processing of DNA double-strand break ends";"Formation of a pool of free 40S subunits";"SCF-beta-TrCP mediated degradation of Emi1";"Stimuli-sensing channels";"Negative regulation of FGFR3 signaling";"Myoclonic epilepsy of Lafora";"Major pathway of rRNA processing in the nucleolus and cytosol";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of FGFR1 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Prevention of phagosomal-lysosomal fusion";"TICAM1,TRAF6-dependent induction of TAK1 complex";"APC-Cdc20 mediated degradation of Nek2A";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PTEN stability and activity";"Peptide chain elongation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Budding and maturation of HIV virion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TCF dependent signaling in response to WNT";"Viral mRNA Translation";"Antigen processing: Ubiquitination & Proteasome degradation";"Assembly Of The HIV Virion";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Translesion synthesis by POLI";"InlA-mediated entry of Listeria monocytogenes into host cells";"Downregulation of ERBB4 signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of innate immune responses to cytosolic DNA";"Regulation of expression of SLITs and ROBOs";"Chaperone Mediated Autophagy";"Spry regulation of FGF signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Oxidative Stress Induced Senescence";"DNA Damage Recognition in GG-NER";"Regulation of TNFR1 signaling";"Separation of Sister Chromatids";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Translesion synthesis by REV1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Cyclin B";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Negative regulation of FGFR2 signaling";"Regulation of PTEN localization";"Termination of translesion DNA synthesis";"Regulation of RAS by GAPs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"ER Quality Control Compartment (ERQC)";"Cargo recognition for clathrin-mediated endocytosis";"TICAM1, RIP1-mediated IKK complex recruitment";"Ribosomal scanning and start codon recognition";"Formation of Incision Complex in GG-NER";"Oncogene Induced Senescence";"Downstream TCR signaling";"IRAK1 recruits IKK complex";"Vif-mediated degradation of APOBEC3G";"Downregulation of ERBB2:ERBB3 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of PLK1 Activity at G2/M Transition" XP_011191205.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_028894261.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_011189403.1 4 MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61 "Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_011187021.1 27 Reactome: R-HSA-6807505;Reactome: R-HSA-77595;Reactome: R-HSA-6803529;Reactome: R-HSA-975957;Reactome: R-HSA-159230;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-159227;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-191859;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-975956;Reactome: R-HSA-111367 "RNA polymerase II transcribes snRNA genes";"Processing of Intronless Pre-mRNAs";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"snRNP Assembly";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Capping";"Formation of the Early Elongation Complex";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SLBP independent Processing of Histone Pre-mRNAs" XP_011193286.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_011176914.1 19 Reactome: R-HSA-428543;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220;Reactome: R-HSA-5663213;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-983231 "Inactivation of CDC42 and RAC1";"Myogenesis";"DCC mediated attractive signaling";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins";"RHO GTPases Activate WASPs and WAVEs";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production" XP_011184578.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011180465.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_028898465.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_028902031.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_028896704.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_011180479.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867 "E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex" XP_028896922.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_011188194.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_028901676.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011183259.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011182052.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_028897987.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011181815.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_028896179.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606 "Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_028900465.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011190287.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_011182742.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_028895549.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_028896345.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_028901012.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_028901832.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_011186927.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028901093.1 19 Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Chylomicron remodeling";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL assembly";"VLDL clearance";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_028898108.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_011183604.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_011188949.1 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204 "Phosphatidylinositol signaling system";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol" XP_011190077.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_011182877.1 29 MetaCyc: PWY-5082;MetaCyc: PWY-6333;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-5057;MetaCyc: PWY-6587;MetaCyc: PWY-3162;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-7118;KEGG: 00071+1.1.1.1;KEGG: 00830+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5078;MetaCyc: PWY-6342;MetaCyc: PWY-6871;MetaCyc: PWY-5079;MetaCyc: PWY-5751;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-7111;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00592+1.1.1.1 "L-methionine degradation III";"Acetaldehyde biosynthesis I";"Tyrosine metabolism";"Salidroside biosynthesis";"L-valine degradation II";"Pyruvate fermentation to ethanol III";"L-tryptophan degradation V (side chain pathway)";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol II";"Chitin degradation to ethanol";"Fatty acid degradation";"Retinol metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol I";"L-isoleucine degradation II";"Noradrenaline and adrenaline degradation";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Phenylethanol biosynthesis";"Chloroalkane and chloroalkene degradation";"Serotonin degradation";"Metabolism of xenobiotics by cytochrome P450";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Glycine, serine and threonine metabolism";"Butanol and isobutanol biosynthesis (engineered)";"alpha-Linolenic acid metabolism" XP_011177670.1 3 KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_011185304.1 4 MetaCyc: PWY-4361;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_028895588.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_011187447.1 4 Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-196741;Reactome: R-HSA-3359462 "Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1" XP_028901681.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011189448.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011183421.1 10 MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842 "Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II" XP_011176825.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_028896963.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_011185446.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_011188502.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_028898165.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_011190762.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_011187305.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_028900785.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_028897241.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_028893905.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_028900845.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_011178737.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_028900836.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_011196912.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011183389.1 56 Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113 "Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1" XP_028898460.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_011181530.1 6 Reactome: R-HSA-8868766;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;MetaCyc: PWY-7286 "rRNA processing in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_011195795.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_011184675.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011190390.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028898450.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_011183232.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011194107.1 26 Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568 "Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase" XP_028899701.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_011186902.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_011181139.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_011178935.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011178665.1 20 MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-735 "6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis" XP_028895270.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_028896343.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_028896361.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_028901831.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_028895644.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_011176938.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_011196511.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_028896354.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_011194571.1 18 Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-1221632;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Meiotic synapsis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes" XP_028894311.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9022692 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity" XP_028899789.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_011177489.1 11 Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580 "activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence" XP_011180351.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_028896758.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Activation of RAC1";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_028898014.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_011196261.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_011192855.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_028901358.1 8 KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1 "Fructose and mannose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_011187495.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_028897059.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011190746.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_011189884.1 44 Reactome: R-HSA-5673001;Reactome: R-HSA-5674499;Reactome: R-HSA-6811558;Reactome: R-HSA-5668599;Reactome: R-HSA-375165;Reactome: R-HSA-8940973;Reactome: R-HSA-9627069;Reactome: R-HSA-198753;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5654733;Reactome: R-HSA-5663213;Reactome: R-HSA-982772;Reactome: R-HSA-1295596;Reactome: R-HSA-5675221;Reactome: R-HSA-170968;Reactome: R-HSA-5674135;Reactome: R-HSA-74749;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.24;Reactome: R-HSA-162658;Reactome: R-HSA-8939211;Reactome: R-HSA-6802955;Reactome: R-HSA-5654727;Reactome: R-HSA-6802946;Reactome: R-HSA-112409;Reactome: R-HSA-5654732;Reactome: R-HSA-202670;Reactome: R-HSA-450341;Reactome: R-HSA-881907;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-456926;Reactome: R-HSA-879415;Reactome: R-HSA-2871796;Reactome: R-HSA-3371453;Reactome: R-HSA-445144;Reactome: R-HSA-6802952;Reactome: R-HSA-2559585;Reactome: R-HSA-5654726;Reactome: R-HSA-2029482 "RAF/MAP kinase cascade";"Negative feedback regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate NADPH Oxidases";"NCAM signaling for neurite out-growth";"RUNX2 regulates osteoblast differentiation";"Regulation of the apoptosome activity";"ERK/MAPK targets";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Negative regulation of FGFR4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Growth hormone receptor signaling";"Spry regulation of FGF signaling";"Negative regulation of MAPK pathway";"Frs2-mediated activation";"MAP2K and MAPK activation";"Signal attenuation";"RSK activation";"mTOR signaling pathway";"Golgi Cisternae Pericentriolar Stack Reorganization";"ESR-mediated signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of FGFR2 signaling";"Signaling by moderate kinase activity BRAF mutants";"RAF-independent MAPK1/3 activation";"Negative regulation of FGFR3 signaling";"ERKs are inactivated";"Activation of the AP-1 family of transcription factors";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Thrombin signalling through proteinase activated receptors (PARs)";"Advanced glycosylation endproduct receptor signaling";"FCERI mediated MAPK activation";"Regulation of HSF1-mediated heat shock response";"Signal transduction by L1";"Signaling by BRAF and RAF fusions";"Oncogene Induced Senescence";"Negative regulation of FGFR1 signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_011176714.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028894212.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011190787.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-983168 "Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"G2/M Checkpoints";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011189128.1 33 Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107 "HCMV Early Events";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"snRNP Assembly";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_011182903.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_028895646.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_011181871.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_011180614.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_028894028.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_028899517.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_011185562.1 7 MetaCyc: PWY-3841;MetaCyc: PWY-6614;Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;KEGG: 00670+1.5.1.3 "Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"One carbon pool by folate" XP_028895844.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions" XP_028896841.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-9604323 "Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling" XP_011193003.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_028894773.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011185190.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_011189712.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_028899648.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_011190886.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_011189115.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_028896347.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_011193157.1 33 Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-159231 "Viral Messenger RNA Synthesis";"HCMV Early Events";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_028894085.1 9 Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-193648;Reactome: R-HSA-2871796 "VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"GPVI-mediated activation cascade";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"NRAGE signals death through JNK";"FCERI mediated MAPK activation" XP_028894844.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-9018519 "Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression" YP_004891173.1 7 MetaCyc: PWY-4302;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;Reactome: R-HSA-611105 "Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis";"Fe(II) oxidation";"Respiratory electron transport" XP_011179061.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_011181670.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028899891.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011193625.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_028895336.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1 "Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Purine metabolism" XP_028898510.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_028893458.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_028894140.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011188141.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_011191912.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_028896478.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_028900033.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028896219.1 14 KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4 "Sphingolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PC";"Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_028900543.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_011183365.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_028894199.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028895488.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_011182756.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899314.1 7 MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25 "Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_011193204.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118 "Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle" XP_028901084.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" XP_011189243.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_028894192.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028896730.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_011189304.1 6 KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290 "Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_028896480.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_011183600.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011189185.1 7 Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis" XP_011188406.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_011177963.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_011188520.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_028897883.1 11 MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7124;MetaCyc: PWY-5913 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)" XP_011178572.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_028898984.1 42 KEGG: 00360+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7656;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6946;MetaCyc: PWY-5789;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-6945;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7401;MetaCyc: PWY-7726;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883 "Phenylalanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Androstenedione degradation";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Fatty acid degradation";"Propanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"2-methylpropene degradation";"Tryptophan metabolism";"Geraniol degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"Fatty acid elongation";"Butanoate metabolism";"Fatty acid salvage";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)" XP_028898350.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028899833.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_011182433.1 5 KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_011178067.1 8 MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates" XP_028899506.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_028893670.1 13 Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802955 "Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_028896081.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_011180808.1 7 MetaCyc: PWY-3561;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166 "Choline biosynthesis III";"Synthesis of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PA" XP_028898688.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_028893725.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_011177794.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011187018.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_011189331.1 6 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism" XP_011179363.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_011192923.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_028900733.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_011190528.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011181715.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_011180591.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_011190905.1 19 KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-7384;Reactome: R-HSA-163765;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5172;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969 "Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_011195961.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_011177934.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_011190896.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_028900732.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_028894120.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_011179269.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011185781.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_011189988.1 23 Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_011188140.1 5 Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_011186795.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028899888.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_011188277.1 12 MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1 "Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Propanoate metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Methane metabolism" XP_028895949.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_011185024.1 8 KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27 "Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism" XP_028894152.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_028895249.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_028896076.1 6 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_028893693.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_028894947.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_028899903.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_011176833.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011176852.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_011191148.1 8 Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_011187587.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_011196406.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_011186853.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028897691.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011193557.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_028898665.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_011191712.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_028898448.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_028894848.1 5 Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-211981 "Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols";"Phase I - Functionalization of compounds";"Xenobiotics" XP_011182434.1 5 KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_011177526.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_028898442.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_028896719.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_011185052.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_011184436.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_011184935.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_028900478.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801 "Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD" XP_011187096.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_028896237.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_011182946.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_028896888.1 3 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214;Reactome: R-HSA-189085 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins";"Digestion of dietary carbohydrate" XP_028901885.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_028898349.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011179475.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_028901509.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_011176906.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-445355 "Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction" XP_011193438.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_011195379.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_011189125.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions" XP_011193523.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011182347.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_011187358.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_011186675.1 24 Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-418592 "Ca2+ pathway";"Presynaptic function of Kainate receptors";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1" XP_011179689.1 13 MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-2261 "4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle" XP_011178267.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_011177719.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_028898611.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_028898681.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_028894134.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_028900995.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-1368082;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RORA activates gene expression";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation" XP_011190159.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_011183468.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_011179056.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_028899773.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_028900450.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_011191555.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_011185699.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_011189084.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_028895746.1 13 KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916 "Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation" XP_011178812.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_028897693.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_011179005.2 9 Reactome: R-HSA-9657050;Reactome: R-HSA-9656255;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702 "Defective OGG1 Localization";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_011180531.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_011184045.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_011189062.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_028898769.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_028899983.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_011193198.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_011184711.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_011184990.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_011187183.1 13 Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-450321 "CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_028899708.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_011188808.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_028897955.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_028901801.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011183825.1 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_011197064.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_028900830.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_028899882.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_028898928.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_011181660.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_011192789.1 8 MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273 "Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_028898012.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_028900616.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_011195234.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_011185632.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_028899925.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_011190870.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_011186913.1 11 KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-5913 "Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)" XP_011195807.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_011178986.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_011186450.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_011178792.2 10 MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484 "Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Galactose metabolism";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)" XP_028896906.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_011178850.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_028901138.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_011186096.1 13 MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52 "Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis" XP_028900250.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_011177068.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_028894202.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028899759.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_011177240.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_011180648.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011196148.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_028894187.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_011178710.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_028896990.1 10 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription" XP_028896273.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_011182932.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_011181683.1 19 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-3214858;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"RMTs methylate histone arginines";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_011195320.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011193668.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_011178358.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_011182040.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_011181766.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_011193527.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_011178142.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_028894026.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_011179136.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_011196958.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_011183568.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_011177783.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011185672.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_028899486.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_011181025.1 22 Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex" XP_028900742.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_011187118.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits" XP_028900310.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_011185021.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_011180960.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_011181809.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_011196556.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_011178429.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_028893718.1 9 KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883 "Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II" XP_028899460.1 20 MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-75105;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-1268020 "Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Mitochondrial protein import" XP_028897945.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_028900328.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_011185833.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_028901380.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-450408 "mTORC1-mediated signalling";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_011184889.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011179593.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_011193805.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_028899615.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_028898709.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_028900134.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_011186472.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_011177813.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_028894215.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_028897069.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_028895051.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_011184069.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_011184212.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880 "Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases" XP_028900074.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_011186751.1 13 Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-177504 "VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling" XP_011196062.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis" XP_011195922.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_011196040.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_011193509.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_011185988.1 5 KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688 "Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism" XP_028896702.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_011188056.1 32 Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-72203 "RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA" XP_011196633.1 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_028897875.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_011192214.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_028899638.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_028900786.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins" XP_028895698.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_011183030.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_011192916.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"