Ceratitis capitata


The medfly has been an established lab organism for several decades, and is notable as being the closest non-drosophilid relative to Drosophila subject to genetic analysis, with broad chromosomal syntenic relationships established. It is also one of the most important agricultural pests worldwide due to its broad plant host range throughout tropical and sub-tropical regions.

Genetic studies have been driven by efforts to use genetic manipulation to improve the sterile insect technique which is used to control medfly and several other tephritid species through multi-tactical integrated pest management approaches. It was among the first non-drosophilid insects to have a polytene chromosomal genetic map created, having ~30 cloned genes mapped by in situ hybridization. It was also the first to have its germ-line efficiently transformed by a transposon-based vector system. It is now a model system for genetic manipulation in non-drosophilids, including functional genomics analysis, new vector systems for transgene stabilization, genomic targeting, and transgenic strains created for population control.

Data were generated as part of the Baylor College of Medicine's i5k pilot project.

Please cite the following publication when using this dataset:
Papanicolaou, Alexie, et al. "The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species." Genome Biology 17.1 (2016): 192.

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Organism Image
Feature Summary
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Contig N50
Scaffold N50
Number Of Genes
Community Contact
Community Contact: 
Al Handler|ahandler@ufl.edu
Image Credit
<a href="https://commons.wikimedia.org/wiki/User:Alvesgaspar">Alvesgaspar. </a> <a href="https://en.wikipedia.org/wiki/File:Fly_October_2008-4.jpg">View Source.</a> <a href="https://creativecommons.org/licenses/by-sa/3.0/deed.en">CC-BY-SA-3.0</a>

Assembly Information

Analysis Name Ceratitis capitata whole genome assembly, NCBI release
Software Baylor College of Medicine genome assembly pipeline, followed by NCBI GenBank and RefSeq processing (NA)
Source ccp_ref_Ccap_1.0
Date performed 2012-05-14
Materials & Methods NCBI genome assembly page
Baylor College of Medicine summary page


Assembly Metrics
Contig N50 45882
Scaffold N50 4060615
GC Content 35.74
Manual Annotations